| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aleksander Talgøy Holten, Holten Aleksander Talgøy, Niels Christian Danbolt, Danbolt Niels Christian, Keiko Shimamoto, Vidar Gundersen, Gundersen Vida. Low-affinity excitatory amino acid uptake in hippocampal astrocytes: a possible role of Na+/dicarboxylate cotransporters. Glia. vol 56. issue 9. 2008-11-12. PMID:18442087. |
here we have visualized "low-affinity" excitatory amino acid uptake sites by incubating rat hippocampal slices with the glutamate analogue d-aspartate in the presence of pmb-tboa, which blocks the eaats. |
2008-11-12 |
2023-08-12 |
rat |
| Lucy M Elphick, Mohammad Hawat, Nick J Toms, Annika Meinander, Andrey Mikhailov, John E Eriksson, George E N Kas. Opposing roles for caspase and calpain death proteases in L-glutamate-induced oxidative neurotoxicity. Toxicology and applied pharmacology. vol 232. issue 2. 2008-11-06. PMID:18687350. |
oxidative glutamate toxicity in ht22 murine hippocampal cells is a model for neuronal death by oxidative stress. |
2008-11-06 |
2023-08-12 |
Not clear |
| André-Guilhem Calas, Olivier Richard, Sandra Même, Jean-Claude Beloeil, Bich-Thuy Doan, Thierry Gefflaut, William Même, Wim E Crusio, Jacques Pichon, Céline Montéco. Chronic exposure to glufosinate-ammonium induces spatial memory impairments, hippocampal MRI modifications and glutamine synthetase activation in mice. Neurotoxicology. vol 29. issue 4. 2008-11-05. PMID:18562008. |
since glutamate is the main neurotransmitter in hippocampus where it plays a crucial role in spatial memory, hippocampal mri texture and spatial memory alterations might be the consequences of hippocampal glutamate homeostasis modification revealed by increased gs activity in hippocampus. |
2008-11-05 |
2023-08-12 |
mouse |
| Kui Wang, Chao Zheng, Chen Wu, Ming Gao, Qiang Liu, Kechun Yang, Kevin Ellsworth, Lin Xu, Jie W. alpha-Chloralose diminishes gamma oscillations in rat hippocampal slices. Neuroscience letters. vol 441. issue 1. 2008-11-05. PMID:18597935. |
it is concluded that alpha-chloralose suppresses hippocampal gamma oscillations without significantly affecting basic synaptic transmission or ionotropic glutamate, choline and glycine receptor function. |
2008-11-05 |
2023-08-12 |
rat |
| Mayuko Takaki, Yuto Ueda, Taku Doi, Keiko Nagatomo, Yoshiya L Murashima, Hiroshi Kanna. Molecular regulation of antioxidant ability in the hippocampus of EL mice. Brain research. vol 1228. 2008-11-03. PMID:18621028. |
in this study, in addition to evaluating the extracellular glutamate concentration, we tried to determine whether or not changes in the expression of cystine/glutamate exchanger (xct) and glutamate transporter take place in the hipp of el. |
2008-11-03 |
2023-08-12 |
mouse |
| Mayuko Takaki, Yuto Ueda, Taku Doi, Keiko Nagatomo, Yoshiya L Murashima, Hiroshi Kanna. Molecular regulation of antioxidant ability in the hippocampus of EL mice. Brain research. vol 1228. 2008-11-03. PMID:18621028. |
i: during the interictal state, dialysate was collected from the ventral hipp using a microdialysis technique, and an extracellular concentration of glutamate ([glu](o)) was measured with hplc-ecd. |
2008-11-03 |
2023-08-12 |
mouse |
| Mayuko Takaki, Yuto Ueda, Taku Doi, Keiko Nagatomo, Yoshiya L Murashima, Hiroshi Kanna. Molecular regulation of antioxidant ability in the hippocampus of EL mice. Brain research. vol 1228. 2008-11-03. PMID:18621028. |
ii: the hippocampal expression of the glutamate transporter and xct was estimated by western blots. |
2008-11-03 |
2023-08-12 |
mouse |
| Francesco Errico, Silvia Rossi, Francesco Napolitano, Valeria Catuogno, Enza Topo, Gilberto Fisone, Antimo D'Aniello, Diego Centonze, Alessandro Usiell. D-aspartate prevents corticostriatal long-term depression and attenuates schizophrenia-like symptoms induced by amphetamine and MK-801. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 41. 2008-11-03. PMID:18842900. |
in the present study, we demonstrated that nonphysiological high levels of d-aspartate (1) increased in vivo nmdar activity, (2) attenuated prepulse inhibition deficits induced by amphetamine and mk-801 [(+)-5-methyl-10,11-dihydro-5h-dibenzo[a,d]-cyclohepten-5,10-imine hydrogen maleate], (3) produced striatal adaptations of glutamate synapses resembling those observed after chronic haloperidol treatment, and (4) enhanced hippocampal nmdar-dependent memory. |
2008-11-03 |
2023-08-12 |
mouse |
| Yang Zhang, Deepa V Venkitaramani, Clare M Gladding, Yongfang Zhang, Pradeep Kurup, Elek Molnar, Graham L Collingridge, Paul J Lombros. The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 42. 2008-10-29. PMID:18923032. |
we found that (rs)-3,5-dihydroxyphenylglycine (dhpg) stimulation triggered a dose-dependent increase in step translation in hippocampal slices and synaptoneurosomes, a process that requires stimulation of mglur5 (metabotropic glutamate receptor 5) and activation of mitogen-activated protein kinases and phosphoinositide-3 kinase pathways. |
2008-10-29 |
2023-08-12 |
mouse |
| Yang Zhang, Deepa V Venkitaramani, Clare M Gladding, Yongfang Zhang, Pradeep Kurup, Elek Molnar, Graham L Collingridge, Paul J Lombros. The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 42. 2008-10-29. PMID:18923032. |
dhpg-induced ampar internalization and tyrosine dephosphorylation of glur2 (glutamate receptor 2) was blocked by a substrate-trapping tat-step [c/s] protein in hippocampal slices and cultures. |
2008-10-29 |
2023-08-12 |
mouse |
| E B Shubenina, V S Kudrin, P M Klodt, A A Pokrovskiĭ, T A Gudasheva, T A Voronina, R U Ostrovskai. [Interstrain differences in the content of excitatory and inhibitory amino acids in the brain of DBA/2J, Balb/c and C57BL/6 mice: characteristics of the effect of a dipeptide antipsychotic drug dilept]. Eksperimental'naia i klinicheskaia farmakologiia. vol 71. issue 4. 2008-10-27. PMID:18819433. |
we have performed a comparative study of the content of glutamate (glu), aspartate (asp), taurine (tau), glycine (gly) and gamma-amino-butyric acid (gaba) in the cortex, hippocampus, and striatum of the dba/2j, balb/c and c57bl/6 mice brain. |
2008-10-27 |
2023-08-12 |
mouse |
| Wei Wang, Zhi Zhang, Jing Shang, Zhen-Zhou Jiang, Shu Wang, Yong Liu, Lu-Yong Zhan. Activation of group I metabotropic glutamate receptors induces long-term depression in the hippocampal CA1 region of adult rats in vitro. Neuroscience research. vol 62. issue 1. 2008-10-24. PMID:18602428. |
however, this synaptic depression could be completely abolished by application of metabotropic glutamate receptor (mglur) antagonist (s)-amethyl-4-carboxyphenylglycine (mcpg) which had no effect on that induced by the same protocol in the 16-day-old rat hippocampus. |
2008-10-24 |
2023-08-12 |
rat |
| Alexander Reznikov, Nadezhda Nosenko, Larisa Tarasenko, Petr Sinitsyn, Lyubov Polyakova, Tamara Mishunin. Neuroendocrine disorders in adult rats treated prenatally with hydrocortisone acetate. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 60. issue 6. 2008-10-23. PMID:18692998. |
male offspring exhibited a decrease of plasma corticosterone response to an acute stress (1h restraint) that was not accompanied by post-stress changes neither in the hypothalamic noradrenaline content nor hippocampal glutamate decarboxylase activity. |
2008-10-23 |
2023-08-12 |
rat |
| C J Peddie, H A Davies, F M Colyer, M G Stewart, J J Rodrígue. Dendritic colocalisation of serotonin1B receptors and the glutamate NMDA receptor subunit NR1 within the hippocampal dentate gyrus: an ultrastructural study. Journal of chemical neuroanatomy. vol 36. issue 1. 2008-10-14. PMID:18572381. |
dendritic colocalisation of serotonin1b receptors and the glutamate nmda receptor subunit nr1 within the hippocampal dentate gyrus: an ultrastructural study. |
2008-10-14 |
2023-08-12 |
Not clear |
| Mordhwaj S Parihar, Elizabeth A Kunz, Gregory J Brewe. Age-related decreases in NAD(P)H and glutathione cause redox declines before ATP loss during glutamate treatment of hippocampal neurons. Journal of neuroscience research. vol 86. issue 10. 2008-09-30. PMID:18438923. |
age-related decreases in nad(p)h and glutathione cause redox declines before atp loss during glutamate treatment of hippocampal neurons. |
2008-09-30 |
2023-08-12 |
rat |
| L R Gorbacheva, T P Storozhevykh, V G Pinelis, O N Davydova, S Ishiwata, S M Strukov. Activated protein C via PAR1 receptor regulates survival of neurons under conditions of glutamate excitotoxicity. Biochemistry. Biokhimiia. vol 73. issue 6. 2008-09-30. PMID:18620539. |
high concentrations of apc (>50 nm) induced the death of hippocampal neurons similarly to the toxic action of glutamate. |
2008-09-30 |
2023-08-12 |
Not clear |
| L R Gorbacheva, T P Storozhevykh, V G Pinelis, O N Davydova, S Ishiwata, S M Strukov. Activated protein C via PAR1 receptor regulates survival of neurons under conditions of glutamate excitotoxicity. Biochemistry. Biokhimiia. vol 73. issue 6. 2008-09-30. PMID:18620539. |
thus, apc at low concentrations, activating par1, prevents the death of hippocampal and cortical neurons under conditions of glutamate excitotoxicity. |
2008-09-30 |
2023-08-12 |
Not clear |
| Laurent Groc, Daniel Choquet, Francis Chaoulof. The stress hormone corticosterone conditions AMPAR surface trafficking and synaptic potentiation. Nature neuroscience. vol 11. issue 8. 2008-09-22. PMID:18622402. |
corticosterone facilitates hippocampal glutamate transmission, but the cellular pathways by which ampa receptor (ampar) signaling is adjusted remain elusive. |
2008-09-22 |
2023-08-12 |
rat |
| Idil Cavus, Jullie W Pan, Hoby P Hetherington, Walid Abi-Saab, Hitten P Zaveri, Kenneth P Vives, John H Krystal, Susan S Spencer, Dennis D Spence. Decreased hippocampal volume on MRI is associated with increased extracellular glutamate in epilepsy patients. Epilepsia. vol 49. issue 8. 2008-09-18. PMID:18410365. |
decreased hippocampal volume on mri is associated with increased extracellular glutamate in epilepsy patients. |
2008-09-18 |
2023-08-12 |
Not clear |
| Idil Cavus, Jullie W Pan, Hoby P Hetherington, Walid Abi-Saab, Hitten P Zaveri, Kenneth P Vives, John H Krystal, Susan S Spencer, Dennis D Spence. Decreased hippocampal volume on MRI is associated with increased extracellular glutamate in epilepsy patients. Epilepsia. vol 49. issue 8. 2008-09-18. PMID:18410365. |
temporal lobe epilepsy (tle) is associated with smaller hippocampal volume and with elevated extracellular (ec) glutamate levels. |
2008-09-18 |
2023-08-12 |
Not clear |