| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Idil Cavus, Jullie W Pan, Hoby P Hetherington, Walid Abi-Saab, Hitten P Zaveri, Kenneth P Vives, John H Krystal, Susan S Spencer, Dennis D Spence. Decreased hippocampal volume on MRI is associated with increased extracellular glutamate in epilepsy patients. Epilepsia. vol 49. issue 8. 2008-09-18. PMID:18410365. |
we investigated the relationship between the hippocampal volume and glutamate in refractory tle patients. |
2008-09-18 |
2023-08-12 |
Not clear |
| Patrick J Mulholland, Ezekiel P Carpenter-Hyland, Matthew C Hearing, Howard C Becker, John J Woodward, L Judson Chandle. Glutamate transporters regulate extrasynaptic NMDA receptor modulation of Kv2.1 potassium channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 35. 2008-09-18. PMID:18753382. |
because nmda-type glutamate receptors are critical regulators of synaptic plasticity, we investigated nmda receptor modulation of kv2.1 channels in rodent hippocampus and cortex. |
2008-09-18 |
2023-08-12 |
mouse |
| Anna Skórzewska, Andrzej Bidziński, Adam Hamed, Małgorzata Lehner, Danuta Turzyńska, Alicja Sobolewska, Jerzy Walkowiak, Adam Płaźni. Changes in hippocampal amino acid concentrations after chronic administration of corticosterone. Pharmacological reports : PR. vol 59. issue 6. 2008-09-17. PMID:18195468. |
the effects of acute rise in corticosterone concentration upon the levels of hippocampal glutamate (glu) are well described. |
2008-09-17 |
2023-08-12 |
rat |
| Anna Skórzewska, Andrzej Bidziński, Adam Hamed, Małgorzata Lehner, Danuta Turzyńska, Alicja Sobolewska, Jerzy Walkowiak, Adam Płaźni. Changes in hippocampal amino acid concentrations after chronic administration of corticosterone. Pharmacological reports : PR. vol 59. issue 6. 2008-09-17. PMID:18195468. |
much less is known about the effect of chronic elevation of glucocorticoids on hippocampal glutamate. |
2008-09-17 |
2023-08-12 |
rat |
| Anna Skórzewska, Andrzej Bidziński, Adam Hamed, Małgorzata Lehner, Danuta Turzyńska, Alicja Sobolewska, Jerzy Walkowiak, Adam Płaźni. Changes in hippocampal amino acid concentrations after chronic administration of corticosterone. Pharmacological reports : PR. vol 59. issue 6. 2008-09-17. PMID:18195468. |
to this end, we have compared the effects of acute and chronic (25 days), administration of corticosterone on the concentration of glutamate, and gamma-aminobutyric acid (gaba), in the dorsal hippocampus, in freely moving rats. |
2008-09-17 |
2023-08-12 |
rat |
| Anna Skórzewska, Andrzej Bidziński, Adam Hamed, Małgorzata Lehner, Danuta Turzyńska, Alicja Sobolewska, Jerzy Walkowiak, Adam Płaźni. Changes in hippocampal amino acid concentrations after chronic administration of corticosterone. Pharmacological reports : PR. vol 59. issue 6. 2008-09-17. PMID:18195468. |
the acute administration of corticosterone (20 mg/kg) produced an expected increase in hippocampal concentration of extracellular glutamate and a smaller but significant enhancement of local concentration of gaba. |
2008-09-17 |
2023-08-12 |
rat |
| Anna Skórzewska, Andrzej Bidziński, Adam Hamed, Małgorzata Lehner, Danuta Turzyńska, Alicja Sobolewska, Jerzy Walkowiak, Adam Płaźni. Changes in hippocampal amino acid concentrations after chronic administration of corticosterone. Pharmacological reports : PR. vol 59. issue 6. 2008-09-17. PMID:18195468. |
most interestingly, a challenge dose of corticosterone given to the animals chronically pretreated with this hormone almost completely depleted hippocampal glutamate, and decreased the glu/gaba ratio. |
2008-09-17 |
2023-08-12 |
rat |
| Anna Skórzewska, Andrzej Bidziński, Adam Hamed, Małgorzata Lehner, Danuta Turzyńska, Alicja Sobolewska, Jerzy Walkowiak, Adam Płaźni. Changes in hippocampal amino acid concentrations after chronic administration of corticosterone. Pharmacological reports : PR. vol 59. issue 6. 2008-09-17. PMID:18195468. |
in summary, the present study showed that chronic administration of corticosterone increased the hippocampal concentration of glutamate. |
2008-09-17 |
2023-08-12 |
rat |
| Takaaki Miyaji, Noriko Echigo, Miki Hiasa, Shigenori Senoh, Hiroshi Omote, Yoshinori Moriyam. Identification of a vesicular aspartate transporter. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 33. 2008-09-16. PMID:18695252. |
aspartate is an excitatory amino acid that is costored with glutamate in synaptic vesicles of hippocampal neurons and synaptic-like microvesicles (slmvs) of pinealocytes and is exocytosed and stimulates neighboring cells by binding to specific cell receptors. |
2008-09-16 |
2023-08-12 |
Not clear |
| Jee Hee Lee, Eun Ok Lee, Jihee Lee Kang, Young Hae Chon. Concomitant degradation of beta-catenin and GSK-3 beta potently contributes to glutamate-induced neurotoxicity in rat hippocampal slice cultures. Journal of neurochemistry. vol 106. issue 3. 2008-09-15. PMID:18445133. |
acute exposure of rat hippocampal slices to glutamate significantly induced cell death, as determined by media lactate dehydrogenase levels and pi staining. |
2008-09-15 |
2023-08-12 |
rat |
| Jee Hee Lee, Eun Ok Lee, Jihee Lee Kang, Young Hae Chon. Concomitant degradation of beta-catenin and GSK-3 beta potently contributes to glutamate-induced neurotoxicity in rat hippocampal slice cultures. Journal of neurochemistry. vol 106. issue 3. 2008-09-15. PMID:18445133. |
these findings together provide the first direct evidence that glutamate promotes the down-regulations of beta-catenin and gsk-3beta, which potently contribute to neurotoxicity in hippocampus during excitotoxic cell death, and a molecular basis for the protection afforded by calpeptin and apv from the neurotoxic effect of glutamate. |
2008-09-15 |
2023-08-12 |
rat |
| Chiara Ballini, Laura Della Corte, Marta Pazzagli, Maria Alessandra Colivicchi, Giancarlo Pepeu, Keith F Tipton, Maria Grazia Giovannin. Extracellular levels of brain aspartate, glutamate and GABA during an inhibitory avoidance response in the rat. Journal of neurochemistry. vol 106. issue 3. 2008-09-15. PMID:18466328. |
the extracellular levels of aspartate, glutamate and gaba were measured by microdialysis, coupled with an hplc method, in rat prefrontal cortex (mpfc) and ventral hippocampus (vh) before and during the performance of a step-down inhibitory task. |
2008-09-15 |
2023-08-12 |
rat |
| Tore Eid, Arko Ghosh, Yue Wang, Henning Beckström, Hitten P Zaveri, Tih-Shih W Lee, James C K Lai, Gauri H Malthankar-Phatak, Nihal C de Laneroll. Recurrent seizures and brain pathology after inhibition of glutamine synthetase in the hippocampus in rats. Brain : a journal of neurology. vol 131. issue Pt 8. 2008-09-15. PMID:18669513. |
an excess of extracellular glutamate in the hippocampus has been linked to the generation of recurrent seizures and brain pathology in patients with medically intractable mesial temporal lobe epilepsy (mtle). |
2008-09-15 |
2023-08-12 |
rat |
| Li-bin Zhan, Hua Sui, Xiao-guang Lu, Chang-kai Sun, Jian Zhang, Hui M. Effects of Zibu Piyin recipe on SNK-SPAR pathway in neuron injury induced by glutamate. Chinese journal of integrative medicine. vol 14. issue 2. 2008-09-08. PMID:18679602. |
to investigate the relationship between the excitotoxicity and serum-inducible kinase (snk) and spine-associated rap gtpase-activating protein (spar) pathway in primary hippocampal neuron injury induced by glutamate and furthermore, to explore the molecular mechanism of neuroprotection of zibu piyin recipe (zbpyr) and the relationship between zbpyr and the morphological regulation of dendritic spines. |
2008-09-08 |
2023-08-12 |
Not clear |
| András Csillag, Eszter Bálint, Agota Adám, Gergely Zacha. The organisation of the basal ganglia in the domestic chick (Gallus domesticus): anatomical localisation of DARPP-32 in relation to glutamate. Brain research bulletin. vol 76. issue 3. 2008-09-04. PMID:18498930. |
using quantitative electron microscopy of chick specimens double-labelled against glutamate and darpp-32 we observed direct synaptic connections between glutamate immunoreactive axon terminals and darpp-32 labelled dendrites in the mst and also in the posterolateral telencephalon (nidopallium caudolaterale, a prefrontal cortex equivalent region) and the hippocampus. |
2008-09-04 |
2023-08-12 |
chicken |
| Mark E Bardgett, Megan Points, Christian Ramsey-Faulkner, Jeff Topmiller, John Roflow, Travis McDaniel, Timberly Lamontagne, Molly S Griffit. The effects of clonidine on discrete-trial delayed spatial alternation in two rat models of memory loss. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 8. 2008-09-02. PMID:17882233. |
spatial memory impairments observed in alzheimer's disease and schizophrenia have been attributed to many factors, including glutamate hypofunction and reduced hippocampal volume. |
2008-09-02 |
2023-08-12 |
rat |
| Mark E Bardgett, Megan Points, Christian Ramsey-Faulkner, Jeff Topmiller, John Roflow, Travis McDaniel, Timberly Lamontagne, Molly S Griffit. The effects of clonidine on discrete-trial delayed spatial alternation in two rat models of memory loss. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 8. 2008-09-02. PMID:17882233. |
taken together, the data indicate that clonidine alleviates memory impairments produced by glutamate hypofunction, but not by hippocampal damage. |
2008-09-02 |
2023-08-12 |
rat |
| Takayoshi Masuoka, Shunsuke Saito, Chiaki Kame. Participation of hippocampal ionotropic glutamate receptors in histamine H(1) antagonist-induced memory deficit in rats. Psychopharmacology. vol 197. issue 1. 2008-08-29. PMID:18066536. |
participation of hippocampal ionotropic glutamate receptors in histamine h(1) antagonist-induced memory deficit in rats. |
2008-08-29 |
2023-08-12 |
rat |
| D J Sanderson, M A Good, P H Seeburg, R Sprengel, J N P Rawlins, D M Bannerma. The role of the GluR-A (GluR1) AMPA receptor subunit in learning and memory. Progress in brain research. vol 169. 2008-08-26. PMID:18394473. |
the expression of long-term potentiation (ltp) in the hippocampus, an experimental model of synaptic plasticity, requires the glur-a subunit of the ampa subtype of glutamate receptor. |
2008-08-26 |
2023-08-12 |
mouse |
| Rui M Barbosa, Cátia F Lourenço, Ricardo M Santos, Francois Pomerleau, Peter Huettl, Greg A Gerhardt, João Laranjinh. In vivo real-time measurement of nitric oxide in anesthetized rat brain. Methods in enzymology. vol 441. 2008-08-26. PMID:18554545. |
we report results from recordings in hippocampus and striatum upon stimulation of n-methyl-d-aspartate-subtype glutamate receptors. |
2008-08-26 |
2023-08-12 |
rat |