| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Reas Khan, Amee Krishnakumar, C S Paulos. Decreased glutamate receptor binding and NMDA R1 gene expression in hippocampus of pilocarpine-induced epileptic rats: neuroprotective role of Bacopa monnieri extract. Epilepsy & behavior : E&B. vol 12. issue 1. 2008-04-11. PMID:18086456. |
we investigated the neuroprotective role of b. monnieri extract in alteration of glutamate receptor binding and gene expression of nmda r1 in hippocampus of temporal lobe epileptic rats. |
2008-04-11 |
2023-08-12 |
rat |
| Juliette E Cheyne, Johanna M Montgomer. Plasticity-dependent changes in metabotropic glutamate receptor expression at excitatory hippocampal synapses. Molecular and cellular neurosciences. vol 37. issue 3. 2008-04-10. PMID:18191411. |
plasticity-dependent changes in metabotropic glutamate receptor expression at excitatory hippocampal synapses. |
2008-04-10 |
2023-08-12 |
Not clear |
| Miguel Salazar, José Antonio Pariente, Ginés María Salido, Antonio Gonzále. Ebselen increases cytosolic free Ca2+ concentration, stimulates glutamate release and increases GFAP content in rat hippocampal astrocytes. Toxicology. vol 244. issue 2-3. 2008-04-09. PMID:18237838. |
ebselen increases cytosolic free ca2+ concentration, stimulates glutamate release and increases gfap content in rat hippocampal astrocytes. |
2008-04-09 |
2023-08-12 |
rat |
| Joanna M Wierońska, Kinga Kłak, Agnieszka Pałucha, Piotr Brański, Andrzej Pil. Citalopram influences mGlu7, but not mGlu4 receptors' expression in the rat brain hippocampus and cortex. Brain research. vol 1184. 2008-04-08. PMID:17976546. |
earlier studies showed that chronic electroconvulsive shock (ecs) or imipramine treatment induced a sub-sensitivity of group i metabotropic glutamate receptors (mglurs) in the hippocampus as well as an increase in the receptor protein level in this structure. |
2008-04-08 |
2023-08-12 |
rat |
| I Kanter-Schlifke, A Toft Sørensen, M Ledri, E Kuteeva, T Hökfelt, M Kokai. Galanin gene transfer curtails generalized seizures in kindled rats without altering hippocampal synaptic plasticity. Neuroscience. vol 150. issue 4. 2008-04-08. PMID:17988802. |
short-term plasticity of mossy fiber-cornu ammonis (ca) 3 synapses was unaltered, as assessed by paired-pulse and frequency facilitation of field excitatory postsynaptic potentials (fepsps) in hippocampal slices, suggesting that despite high transgene galanin expression, overall release probability of glutamate in these synapses was unaffected. |
2008-04-08 |
2023-08-12 |
rat |
| Dmitri Leonoudakis, Pingwei Zhao, Eric C Beatti. Rapid tumor necrosis factor alpha-induced exocytosis of glutamate receptor 2-lacking AMPA receptors to extrasynaptic plasma membrane potentiates excitotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 9. 2008-04-08. PMID:18305246. |
our previous studies show that a major component of this response, the inflammatory cytokine tumor necrosis factor alpha (tnfalpha), causes a rapid increase in ampa glutamate receptors (ampars) on the plasma membrane of cultured hippocampal neurons. |
2008-04-08 |
2023-08-12 |
Not clear |
| Kentaro Matsuzaki, Kenichi Miyazaki, Seiichiro Sakai, Hiromu Yawo, Norihito Nakata, Shigeki Moriguchi, Kohji Fukunaga, Akihito Yokosuka, Yutaka Sashida, Yoshihiro Mimaki, Tohru Yamakuni, Yasushi Ohizum. Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus. European journal of pharmacology. vol 578. issue 2-3. 2008-04-03. PMID:17976577. |
nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase a-mediated phosphorylation of the ampa receptor subunit, glur1, and the postsynaptic receptor response to glutamate in murine hippocampus. |
2008-04-03 |
2023-08-12 |
Not clear |
| P F Simões, A P Silva, F C Pereira, E Marques, S Grade, N Milhazes, F Borges, C F Ribeiro, T R Maced. Methamphetamine induces alterations on hippocampal NMDA and AMPA receptor subunit levels and impairs spatial working memory. Neuroscience. vol 150. issue 2. 2008-04-03. PMID:17981398. |
in the present study, we investigated the effect of acute (30 mg/kg) versus escalating dose (ed) administration of meth on nmda receptor 1, nmda receptor 2 and glutamate receptor 2 (glur2) subunit expression in the hippocampus and on memory. |
2008-04-03 |
2023-08-12 |
rat |
| Simone Molz, Helena Decker, Tharine Dal-Cim, Carla Cremonez, Fabiano M Cordova, Rodrigo B Leal, Carla I Tasc. Glutamate-induced toxicity in hippocampal slices involves apoptotic features and p38 MAPK signaling. Neurochemical research. vol 33. issue 1. 2008-04-01. PMID:17616814. |
hippocampal slices exposed to 1 or 10 mm glutamate for 1 h and evaluated after 6 h, showed reduced cell viability, without altering membrane permeability. |
2008-04-01 |
2023-08-12 |
Not clear |
| Simone Molz, Helena Decker, Tharine Dal-Cim, Carla Cremonez, Fabiano M Cordova, Rodrigo B Leal, Carla I Tasc. Glutamate-induced toxicity in hippocampal slices involves apoptotic features and p38 MAPK signaling. Neurochemical research. vol 33. issue 1. 2008-04-01. PMID:17616814. |
glutamate-induced impairment of hippocampal cell viability was completely blocked by mk-801 (non-competitive antagonist of nmda receptors) and gams (antagonist of ka/ampa glutamate receptors). |
2008-04-01 |
2023-08-12 |
Not clear |
| Simone Molz, Helena Decker, Tharine Dal-Cim, Carla Cremonez, Fabiano M Cordova, Rodrigo B Leal, Carla I Tasc. Glutamate-induced toxicity in hippocampal slices involves apoptotic features and p38 MAPK signaling. Neurochemical research. vol 33. issue 1. 2008-04-01. PMID:17616814. |
in the present study we have shown that glutamate induces apoptosis in hippocampal slices and it causes an impairment of cell viability that was dependent of ionotropic and metabotropic receptors activation and, may involve the activation of p38 mapk pathway. |
2008-04-01 |
2023-08-12 |
Not clear |
| Jing-Jer Ke, Hsiun-Ing Chen, Chauying J Jen, Yu-Min Kuo, Chianfang G Cherng, Yen-Ping N Tsai, Ming-Che Ho, Chia-Wen Tsai, Lung Y. Mutual enhancement of central neurotoxicity induced by ketamine followed by methamphetamine. Toxicology and applied pharmacology. vol 227. issue 2. 2008-03-31. PMID:18076959. |
likewise, the subsequent treatment with methamphetamine exacerbated the ketamine-induced glutamatergic damage as indicated by reduced levels of the vesicular glutamate transporter in hippocampus and striatum and poor memory performance in the morris water maze. |
2008-03-31 |
2023-08-12 |
mouse |
| Liang Zhang, Jiwei He, Denis G M Jugloff, James H Eubank. The MeCP2-null mouse hippocampus displays altered basal inhibitory rhythms and is prone to hyperexcitability. Hippocampus. vol 18. issue 3. 2008-03-27. PMID:18058824. |
this reduction was not associated with alterations in the gross electrophysiological properties of hippocampal neurons, but was associated with a decreased level of spontaneous glutamate receptor-mediated synaptic currents in hippocampal ca3 neurons. |
2008-03-27 |
2023-08-12 |
mouse |
| Alexander Kulla, Denise Manahan-Vaugha. Modulation by group 1 metabotropic glutamate receptors of depotentiation in the dentate gyrus of freely moving rats. Hippocampus. vol 18. issue 1. 2008-03-18. PMID:17924526. |
activation of group 1 metabotropic glutamate receptors (mglurs) is critically required for both hippocampal long-term potentiation (ltp) and ltd in vivo, but their involvement in depotentiation is unclear. |
2008-03-18 |
2023-08-12 |
rat |
| P Maciejak, M Lehner, D Turzyńska, J Szyndler, A Bidziński, E Taracha, A Sobolewska, J Walkowiak, A Skórzewska, A Wisłowska, A Hamed, A Płaźni. The opposite role of hippocampal mGluR1 in fear conditioning in kindled and non-kindled rats. Brain research. vol 1187. 2008-03-17. PMID:18022605. |
in the present paper, we analyzed the effects of hippocampal mglur1 on the consolidation of a fear-conditioned response and on hippocampal glutamate and gaba concentration in rats subjected to the chemically-induced kindling of seizures. |
2008-03-17 |
2023-08-12 |
rat |
| José Carlos González, Javier Egea, María Del Carmen Godino, Francisco J Fernandez-Gomez, José Sánchez-Prieto, Luís Gandía, Antonio G García, Joaquín Jordán, Jesús M Hernández-Guij. Neuroprotectant minocycline depresses glutamatergic neurotransmission and Ca(2+) signalling in hippocampal neurons. The European journal of neuroscience. vol 26. issue 9. 2008-03-14. PMID:17986028. |
in an attempt to clarify this mechanism, we have studied here its effects on various electrophysiological parameters, ca(2+) signalling, and glutamate release, in primary cultures of rat hippocampal neurons, and in synaptosomes. |
2008-03-14 |
2023-08-12 |
rat |
| J V Negrete-Díaz, T S Sihra, J M Delgado-García, A Rodríguez-Moren. Kainate receptor-mediated presynaptic inhibition converges with presynaptic inhibition mediated by Group II mGluRs and long-term depression at the hippocampal mossy fiber-CA3 synapse. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 11. 2008-03-11. PMID:17510730. |
kainate receptors (kars) effect depression of glutamate release at hippocampal mossy fiber-ca3 (mf-ca3) synapses by a metabotropic action involving adenylyl cyclase (ac) inhibition, camp reduction, and diminished protein kinase a (pka) activation. |
2008-03-11 |
2023-08-12 |
Not clear |
| J V Negrete-Díaz, T S Sihra, J M Delgado-García, A Rodríguez-Moren. Kainate receptor-mediated presynaptic inhibition converges with presynaptic inhibition mediated by Group II mGluRs and long-term depression at the hippocampal mossy fiber-CA3 synapse. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 11. 2008-03-11. PMID:17510730. |
using hippocampal slices, we show here that kar activation interferes with the depression of glutamate release produced by group ii metabotropic glutamate receptor stimulation and low frequency stimulation (lfs)-induced long-term depression (ltd), also expressed through presynaptic ac/camp/pka at mf-ca3 synapses. |
2008-03-11 |
2023-08-12 |
Not clear |
| Josefine Andin, Martin Hallbeck, Abdul H Mohammed, Jan Marcusso. Influence of environmental enrichment on steady-state mRNA levels for EAAC1, AMPA1 and NMDA2A receptor subunits in rat hippocampus. Brain research. vol 1174. 2008-03-10. PMID:17854777. |
glutamatergic pathways are imperative for cognitive functions, such as memory, learning and long-term potentiation, and relies on the ampa and nmda glutamate receptors and the hippocampus, with its specific subregions, is an important anatomical substrate in this. |
2008-03-10 |
2023-08-12 |
rat |
| Josefine Andin, Martin Hallbeck, Abdul H Mohammed, Jan Marcusso. Influence of environmental enrichment on steady-state mRNA levels for EAAC1, AMPA1 and NMDA2A receptor subunits in rat hippocampus. Brain research. vol 1174. 2008-03-10. PMID:17854777. |
the glutamate signalling is also dependent on a fine-tuned transport system, in the hippocampus primarily achieved by the glutamate transporter eaac1. |
2008-03-10 |
2023-08-12 |
rat |