| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jie Zhou, Hongxing Wang, Yufang Xiong, Zixi Li, Youmei Feng, Juan Che. Puerarin attenuates glutamate-induced neurofilament axonal transport impairment. Journal of ethnopharmacology. vol 132. issue 1. 2011-02-09. PMID:20727960. |
since it has been postulated that pur protects the brain against glutamate (glu) neurotoxicity, we investigated the effects of pur on glu-induced axonal transport impairment in primary hippocampal neurons in this study. |
2011-02-09 |
2023-08-12 |
Not clear |
| Marcia D Antion, Louisa A Christie, Allison M Bond, Matthew B Dalva, Anis Contracto. Ephrin-B3 regulates glutamate receptor signaling at hippocampal synapses. Molecular and cellular neurosciences. vol 45. issue 4. 2011-02-07. PMID:20678574. |
ephrin-b3 regulates glutamate receptor signaling at hippocampal synapses. |
2011-02-07 |
2023-08-12 |
mouse |
| Brigitte Potier, Jean-Marie Billard, Sylvain Rivière, Pierre-Marie Sinet, Isabelle Denis, Gaelle Champeil-Potokar, Barbara Grintal, Anne Jouvenceau, Melanie Kollen, Patrick Duta. Reduction in glutamate uptake is associated with extrasynaptic NMDA and metabotropic glutamate receptor activation at the hippocampal CA1 synapse of aged rats. Aging cell. vol 9. issue 5. 2011-02-04. PMID:20569241. |
a decrease in the expression of the glial glutamate transporters glast and glt-1 and reduced glutamate uptake occur in the aged (24-27 months) sprague-dawley rat hippocampus. |
2011-02-04 |
2023-08-12 |
rat |
| Brigitte Potier, Jean-Marie Billard, Sylvain Rivière, Pierre-Marie Sinet, Isabelle Denis, Gaelle Champeil-Potokar, Barbara Grintal, Anne Jouvenceau, Melanie Kollen, Patrick Duta. Reduction in glutamate uptake is associated with extrasynaptic NMDA and metabotropic glutamate receptor activation at the hippocampal CA1 synapse of aged rats. Aging cell. vol 9. issue 5. 2011-02-04. PMID:20569241. |
glutamatergic excitatory postsynaptic potentials recorded extracellularly in ex vivo hippocampal slices from adult (3-5 months) and aged rats are depressed by dl-tboa, an inhibitor of glutamate transporter activity, in an n-methyl-d-aspartate (nmda)-receptor-dependent manner. |
2011-02-04 |
2023-08-12 |
rat |
| Brian Tucker, James E Olso. Glutamate receptor-mediated taurine release from the hippocampus during oxidative stress. Journal of biomedical science. vol 17 Suppl 1. 2011-02-01. PMID:20804584. |
glutamate receptor-mediated taurine release from the hippocampus during oxidative stress. |
2011-02-01 |
2023-08-12 |
Not clear |
| E Sherwood Brown, Liam Zaidel, Greg Allen, Roderick McColl, Miguel Vazquez, Wendy K Ring. Effects of lamotrigine on hippocampal activation in corticosteroid-treated patients. Journal of affective disorders. vol 126. issue 3. 2011-01-26. PMID:20580827. |
in animals, agents that decrease glutamate release attenuate the effects of corticosteroids on the hippocampus. |
2011-01-26 |
2023-08-12 |
human |
| Eva C Bunk, Hans-Georg König, Helena P Bonner, Brian P Kirby, Jochen H M Preh. NMDA-induced injury of mouse organotypic hippocampal slice cultures triggers delayed neuroblast proliferation in the dentate gyrus: an in vitro model for the study of neural precursor cell proliferation. Brain research. vol 1359. 2011-01-25. PMID:20478273. |
a brief exposure of 8-day-old hippocampal slice cultures to the glutamate receptor agonist n-methyl-d-aspartate (nmda; 20-50µm for 30 min) caused a selective excitotoxic injury in the ca1 subfield of the hippocampus that matured over a period of 24h. |
2011-01-25 |
2023-08-12 |
mouse |
| Emilia H Moscato, Ankit Jain, Xiaoyu Peng, Ethan G Hughes, Josep Dalmau, Rita J Balice-Gordo. Mechanisms underlying autoimmune synaptic encephalitis leading to disorders of memory, behavior and cognition: insights from molecular, cellular and synaptic studies. The European journal of neuroscience. vol 32. issue 2. 2011-01-25. PMID:20646055. |
recently, several novel, potentially lethal and treatment-responsive syndromes that affect hippocampal and cortical function have been shown to be associated with auto-antibodies against synaptic antigens, notably glutamate or gaba-b receptors. |
2011-01-25 |
2023-08-12 |
Not clear |
| Priscila Gubert, Daiana Silva Avila, Jessika Cristina Bridi, Sara Saurin, Thiago Henrique Lugokenski, Jardel Gomes Villarinho, Roselei Fachinetto, Maria Ester Pereira, Juliano Ferreira, João Batista Teixeira da Rocha, Félix Alexandre Antunes Soare. Low concentrations of methamidophos do not alter AChE activity but modulate neurotransmitters uptake in hippocampus and striatum in vitro. Life sciences. vol 88. issue 1-2. 2011-01-21. PMID:21075126. |
as the mechanism of its neurotoxic effects is not well understood, the aim of the present study was to evaluate the effects of meth on glutamate and gamma aminobutyric acid (gaba) uptake and correlate with cell viability and ache and na(+)/k(+)-atpase enzyme activities in striatum and hippocampus slices exposed to low concentrations (0.05 to 1.0 μm) of meth. |
2011-01-21 |
2023-08-12 |
Not clear |
| Eiki Takahashi, Kimie Niimi, Chitoshi Itakur. Subthreshold pharmacological and genetic approaches to analyzing CaV2.1-mediated NMDA receptor signaling in short-term memory. European journal of pharmacology. vol 645. issue 1-3. 2011-01-19. PMID:20670620. |
recently, the antiepileptic drug levetiracetam was reported to inhibit presynaptic ca(v)2.1 functions, reducing glutamate release in the hippocampus, although the precise physiological role of ca(v)2.1-regulated synaptic functions in cognitive performance at the system level remains unknown. |
2011-01-19 |
2023-08-12 |
mouse |
| Piotr Maciejak, Janusz Szyndler, Danuta Turzyńska, Alicja Sobolewska, Andrzej Bidziński, Karolina Kołosowska, Adam Płaźni. Time course of changes in the concentrations of amino acids in the brain structures of pentylenetetrazole-kindled rats. Brain research. vol 1342. 2011-01-18. PMID:20420810. |
at the fifth stage of kindling, glutamate was elevated in the amygdala, nucleus accumbens and piriform cortex, whereas alanine content was increased in the hippocampus, amygdala, striatum, nucleus accumbens and piriform cortex. |
2011-01-18 |
2023-08-12 |
rat |
| Eunkuk Park, Gi Ja Lee, Samjin Choi, Seok Keun Choi, Su Jin Chae, Sung Wook Kang, Hun-Kuk Par. Correlation between extracellular glutamate release and neuronal cell death in an eleven vessel occlusion model in rat. Brain research. vol 1342. 2011-01-18. PMID:20427014. |
unlike the small amount of brain damage in the 5-min group, the increased glutamate levels in the 10-min group resulted in ischemic cell death in the hippocampal region with the activation of cleaved caspase-3 and the inhibition of neuron-specific nuclear protein expression. |
2011-01-18 |
2023-08-12 |
rat |
| Andrew J Giessel, Bernardo L Sabatin. M1 muscarinic receptors boost synaptic potentials and calcium influx in dendritic spines by inhibiting postsynaptic SK channels. Neuron. vol 68. issue 5. 2011-01-18. PMID:21145006. |
within the hippocampus, machrs promote nmda-type glutamate receptor-dependent forms of long-term potentiation. |
2011-01-18 |
2023-08-12 |
Not clear |
| James M Stone, Oliver D Howes, Alice Egerton, Joseph Kambeitz, Paul Allen, David J Lythgoe, Ruth L O'Gorman, Mary A McLean, Gareth J Barker, Philip McGuir. Altered relationship between hippocampal glutamate levels and striatal dopamine function in subjects at ultra high risk of psychosis. Biological psychiatry. vol 68. issue 7. 2011-01-13. PMID:20638047. |
altered relationship between hippocampal glutamate levels and striatal dopamine function in subjects at ultra high risk of psychosis. |
2011-01-13 |
2023-08-12 |
human |
| Ralph Clinckers, Tine Zgavc, Katia Vermoesen, Alfred Meurs, Yvette Michotte, Ilse Smolder. Pharmacological and neurochemical characterization of the involvement of hippocampal adrenoreceptor subtypes in the modulation of acute limbic seizures. Journal of neurochemistry. vol 115. issue 6. 2011-01-04. PMID:20969569. |
interestingly, α(1a) -receptor stimulation and α(1d) -antagonism alone also inhibited seizures associated with respectively significant hippocampal gaba increases and glutamate decreases. |
2011-01-04 |
2023-08-12 |
Not clear |
| Torun Melø, Paolo Bigini, Ursula Sonnewald, Silvia Balosso, Alfredo Cagnotto, Sara Barbera, Sarah Uboldi, Annamaria Vezzani, Tiziana Mennin. Neuronal hyperexcitability and seizures are associated with changes in glial-neuronal interactions in the hippocampus of a mouse model of epilepsy with mental retardation. Journal of neurochemistry. vol 115. issue 6. 2011-01-04. PMID:21044073. |
however, ex vivo(13) c magnetic resonance spectroscopy, after simultaneous injection of [1-(13) c]glucose and [1,2-(13) c]acetate, followed by decapitation, showed decreased [1,2-(13) c]gaba formation from hippocampal astrocytic precursors and a marked reduction in [4,5-(13) c]glutamate derived from glutamine. |
2011-01-04 |
2023-08-12 |
mouse |
| Shi-Jie Liu, Robert Gasperini, Lisa Foa, David Henry Smal. Amyloid-beta decreases cell-surface AMPA receptors by increasing intracellular calcium and phosphorylation of GluR2. Journal of Alzheimer's disease : JAD. vol 21. issue 2. 2010-12-20. PMID:20571220. |
in the present study, we found that abeta significantly decreased levels of the cell-surface ampa-type glutamate receptor subunit 2 (glur2), and increased the concentration of free cytosolic calcium ion ([ca2+]i) in hippocampal neurons. |
2010-12-20 |
2023-08-12 |
Not clear |
| Neelima Bhargava, Mainak Das, Darin Edwards, Maria Stancescu, Jung-Fong Kang, James J Hickma. Coexpression of glutamate vesicular transporter (VGLUT1) and choline acetyltransferase (ChAT) proteins in fetal rat hippocampal neurons in culture. In vitro cellular & developmental biology. Animal. vol 46. issue 8. 2010-12-17. PMID:20632124. |
coexpression of glutamate vesicular transporter (vglut1) and choline acetyltransferase (chat) proteins in fetal rat hippocampal neurons in culture. |
2010-12-17 |
2023-08-12 |
rat |
| Masayuki Fukui, Hye Joung Choi, Bao Ting Zh. Mechanism for the protective effect of resveratrol against oxidative stress-induced neuronal death. Free radical biology & medicine. vol 49. issue 5. 2010-12-15. PMID:20542495. |
cultured ht22 cells, an immortalized mouse hippocampal neuronal cell line, were used as an in vitro model, and oxidative stress and neurotoxicity were induced in these neuronal cells by exposure to high concentrations of glutamate. |
2010-12-15 |
2023-08-12 |
mouse |
| Katsuhiro Kawaai, Keiko Tominaga-Yoshino, Tomoyoshi Urakubo, Naoko Taniguchi, Yasumitsu Kondoh, Hideo Tashiro, Akihiko Ogura, Tomoko Tashir. Analysis of gene expression changes associated with long-lasting synaptic enhancement in hippocampal slice cultures after repetitive exposures to glutamate. Journal of neuroscience research. vol 88. issue 13. 2010-12-06. PMID:20568283. |
analysis of gene expression changes associated with long-lasting synaptic enhancement in hippocampal slice cultures after repetitive exposures to glutamate. |
2010-12-06 |
2023-08-12 |
rat |