| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maria Lindskog, Li Li, Rachel D Groth, Damon Poburko, Tara C Thiagarajan, Xue Han, Richard W Tsie. Postsynaptic GluA1 enables acute retrograde enhancement of presynaptic function to coordinate adaptation to synaptic inactivity. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 50. 2011-05-12. PMID:21098665. |
prolonged blockade of ampa-type glutamate receptors in hippocampal neuron cultures leads to homeostatic enhancements of pre- and postsynaptic function that appear correlated at individual synapses, suggesting some form of transsynaptic coordination. |
2011-05-12 |
2023-08-12 |
Not clear |
| Pierre Lavenex, Steven G Sugden, Ryan R Davis, Jeffrey P Gregg, Pamela Banta Lavene. Developmental regulation of gene expression and astrocytic processes may explain selective hippocampal vulnerability. Hippocampus. vol 21. issue 2. 2011-05-06. PMID:20014383. |
here, we show that the expression of genes associated with glycolysis and glutamate metabolism in astrocytes and the coverage of excitatory synapses by astrocytic processes undergo significant decreases in the ca1 field of the monkey hippocampus during postnatal development. |
2011-05-06 |
2023-08-12 |
monkey |
| Francis Chaouloff, Laurent Gro. Temporal modulation of hippocampal excitatory transmission by corticosteroids and stress. Frontiers in neuroendocrinology. vol 32. issue 1. 2011-05-04. PMID:20647018. |
the first goal of this review is to detail the tonic and intrinsic effects of corticosteroid hormones on hippocampal excitatory transmission, glutamate receptor trafficking and expression, and synaptic plasticity, paying attention to their temporality (rapid and transient effects followed by slow and persistent genomic effects). |
2011-05-04 |
2023-08-12 |
Not clear |
| Bryony A Dickinson, Jihoon Jo, Heon Seok, Gi Hoon Son, Daniel J Whitcomb, Ceri H Davies, Morgan Sheng, Graham L Collingridge, Kwangwook Ch. A novel mechanism of hippocampal LTD involving muscarinic receptor-triggered interactions between AMPARs, GRIP and liprin-alpha. Molecular brain. vol 2. 2011-05-02. PMID:19534762. |
long-term depression (ltd) in the hippocampus can be induced by activation of different types of g-protein coupled receptors, in particular metabotropic glutamate receptors (mglurs) and muscarinic acetylcholine receptors (machrs). |
2011-05-02 |
2023-08-12 |
Not clear |
| Arabinda Das, Misty McDowell, Casey M O'Dell, Megan E Busch, Joshua A Smith, Swapan K Ray, Naren L Bani. Post-treatment with voltage-gated Na(+) channel blocker attenuates kainic acid-induced apoptosis in rat primary hippocampal neurons. Neurochemical research. vol 35. issue 12. 2011-04-28. PMID:21127971. |
injection of rats with kainic acid (ka), a non-n-methyl-d-aspartate (nmda) type glutamate receptor agonist, induces recurrent (delayed) convulsive seizures and subsequently hippocampal neurodegeneration, which is reminiscent of human epilepsy. |
2011-04-28 |
2023-08-12 |
human |
| Elvar M Eyjolfsson, Linn Hege Nilsen, Daniel Kondziella, Eiliv Brenner, Asta Håberg, Ursula Sonnewal. Altered 13C glucose metabolism in the cortico-striato-thalamo-cortical loop in the MK-801 rat model of schizophrenia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 31. issue 3. 2011-04-27. PMID:21081956. |
the largest reductions in glutamate labeling were detected in fcx and ptcx, whereas in hippocampus, striatum, and nac, (13)c labeling of glutamate was only slightly but significantly reduced. |
2011-04-27 |
2023-08-12 |
rat |
| Diogo Losch de Oliveira, Caren Bavaresco, Ben Hur Mussulini, Alice Fischer, Diogo Onofre Souza, Angela T S Wyse, Susana Wofchu. Early life LiCl-pilocarpine-induced status epilepticus reduces acutely hippocampal glutamate uptake and Na+/K+ ATPase activity. Brain research. vol 1369. 2011-04-21. PMID:20977896. |
early life licl-pilocarpine-induced status epilepticus reduces acutely hippocampal glutamate uptake and na+/k+ atpase activity. |
2011-04-21 |
2023-08-12 |
rat |
| Diogo Losch de Oliveira, Caren Bavaresco, Ben Hur Mussulini, Alice Fischer, Diogo Onofre Souza, Angela T S Wyse, Susana Wofchu. Early life LiCl-pilocarpine-induced status epilepticus reduces acutely hippocampal glutamate uptake and Na+/K+ ATPase activity. Brain research. vol 1369. 2011-04-21. PMID:20977896. |
status epilepticus-induced hippocampal neuronal loss is mainly associated with excitotoxicity induced by increased levels of extracellular glutamate which is normally neutralized by high-affinity uptake mechanism. |
2011-04-21 |
2023-08-12 |
rat |
| Diogo Losch de Oliveira, Caren Bavaresco, Ben Hur Mussulini, Alice Fischer, Diogo Onofre Souza, Angela T S Wyse, Susana Wofchu. Early life LiCl-pilocarpine-induced status epilepticus reduces acutely hippocampal glutamate uptake and Na+/K+ ATPase activity. Brain research. vol 1369. 2011-04-21. PMID:20977896. |
in this study, we investigated the effect of early-life-induced status epilepticus on hippocampal na(+)/k(+) atpase activity and glutamate uptake. |
2011-04-21 |
2023-08-12 |
rat |
| Diogo Losch de Oliveira, Caren Bavaresco, Ben Hur Mussulini, Alice Fischer, Diogo Onofre Souza, Angela T S Wyse, Susana Wofchu. Early life LiCl-pilocarpine-induced status epilepticus reduces acutely hippocampal glutamate uptake and Na+/K+ ATPase activity. Brain research. vol 1369. 2011-04-21. PMID:20977896. |
hippocampal na(+)/k(+) atpase activity and glutamate uptake were evaluated 1.5, 12 and 24 h after se induction. |
2011-04-21 |
2023-08-12 |
rat |
| Diogo Losch de Oliveira, Caren Bavaresco, Ben Hur Mussulini, Alice Fischer, Diogo Onofre Souza, Angela T S Wyse, Susana Wofchu. Early life LiCl-pilocarpine-induced status epilepticus reduces acutely hippocampal glutamate uptake and Na+/K+ ATPase activity. Brain research. vol 1369. 2011-04-21. PMID:20977896. |
in conclusion, se induced early in life causes short-term disruption in hippocampal na(+)/k(+) atpase activity and glutamate uptake, which may be related to neuronal death found in ca1 subfield. |
2011-04-21 |
2023-08-12 |
rat |
| Timothy B Johnstone, Zhenglin Gu, Ryan F Yoshimura, Anne-Sophie Villegier, Derk J Hogenkamp, Edward R Whittemore, Jin-Cheng Huang, Minhtam B Tran, James D Belluzzi, Jerrel L Yakel, Kelvin W Ge. Allosteric modulation of related ligand-gated ion channels synergistically induces long-term potentiation in the hippocampus and enhances cognition. The Journal of pharmacology and experimental therapeutics. vol 336. issue 3. 2011-04-21. PMID:21159751. |
postsynaptic α7 nachrs in the hippocampus regulate inhibitory gabaergic interneuron activity required for synchronization of pyramidal neurons in the ca1, whereas presynaptic α7 nachrs regulate glutamate release. |
2011-04-21 |
2023-08-12 |
rat |
| Sunil Kumar Hota, Kalpana Barhwal Hota, Dipti Prasad, Govindasamy Ilavazhagan, Shashi Bala Sing. Oxidative-stress-induced alterations in Sp factors mediate transcriptional regulation of the NR1 subunit in hippocampus during hypoxia. Free radical biology & medicine. vol 49. issue 2. 2011-04-19. PMID:20381604. |
the hippocampus, in particular, is highly vulnerable to hypoxic insult, which at least in part can be attributed to the occurrence of glutamate excitotoxicity. |
2011-04-19 |
2023-08-12 |
Not clear |
| Shuhua Xi, Li Guo, Rong Qi, Wenjuan Sun, Yaping Jin, Guifan Su. Prenatal and early life arsenic exposure induced oxidative damage and altered activities and mRNA expressions of neurotransmitter metabolic enzymes in offspring rat brain. Journal of biochemical and molecular toxicology. vol 24. issue 6. 2011-04-18. PMID:20376865. |
activity of acetylcholinesterase was significantly higher in 100 mg/l as-exposed pup's hippocampus than in control group on pnd 28 and 42. mrna expression of glutamate decarboxylase (gad(65) and gad(67)) in 100 mg/l as-exposed pup's cortex or hippocampus on pnd 28 and 42 were significantly higher than in control (p < 0.05). |
2011-04-18 |
2023-08-12 |
rat |
| K Hanamura, T Mizui, T Kakizaki, R T Roppongi, H Yamazaki, Y Yanagawa, T Shira. Low accumulation of drebrin at glutamatergic postsynaptic sites on GABAergic neurons. Neuroscience. vol 169. issue 4. 2011-04-18. PMID:20600648. |
in the present study, we used hippocampal neuronal cultures prepared from glutamate decarboxylase 67 (gad67)-gfp knock-in mice and analyzed the differences in the actin cytoskeleton at glutamatergic synapses contacting gabaergic and glutamatergic neurons. |
2011-04-18 |
2023-08-12 |
mouse |
| A H Iyo, A M Feyissa, A Chandran, M C Austin, S Regunathan, B Karolewic. Chronic corticosterone administration down-regulates metabotropic glutamate receptor 5 protein expression in the rat hippocampus. Neuroscience. vol 169. issue 4. 2011-04-18. PMID:20600666. |
chronic corticosterone administration down-regulates metabotropic glutamate receptor 5 protein expression in the rat hippocampus. |
2011-04-18 |
2023-08-12 |
rat |
| Rafal M Kaminski, Juan F Núñez-Taltavull, Bogusława Budziszewska, Władysław Lasoń, Maciej Gasior, Agustin Zapata, Toni S Shippenberg, Jeffrey M Witki. Effects of cocaine-kindling on the expression of NMDA receptors and glutamate levels in mouse brain. Neurochemical research. vol 36. issue 1. 2011-04-18. PMID:20927585. |
basal overflow of glutamate in the ventral hippocampus determined by microdialysis in freely moving animals also did not differ between cocaine-kindled and control groups. |
2011-04-18 |
2023-08-12 |
mouse |
| Janelle Drouin-Ouellet, Anna-Liisa Brownell, Martine Saint-Pierre, Caroline Fasano, Vincent Emond, Louis-Eric Trudeau, Daniel Lévesque, Francesca Cicchett. Neuroinflammation is associated with changes in glial mGluR5 expression and the development of neonatal excitotoxic lesions. Glia. vol 59. issue 2. 2011-04-14. PMID:21125661. |
we investigated the contribution of inflammation to the alteration of normal brain circuitries in the context of neuroexcitotoxicity following neonatal ventral hippocampal lesions in rats with ibotenic acid, an nmda glutamate receptor agonist. |
2011-04-14 |
2023-08-12 |
rat |
| Apirada Sucontphunt, Wanchai De-Eknamkul, Ubonthip Nimmannit, S Dan Dimitrijevich, Robert W Grac. Protection of HT22 neuronal cells against glutamate toxicity mediated by the antioxidant activity of Pueraria candollei var. mirifica extracts. Journal of natural medicines. vol 65. issue 1. 2011-03-31. PMID:20658198. |
pm extract was evaluated for its antioxidant and neuroprotective activities against glutamate toxicity in mouse hippocampal ht22 neuronal cells. |
2011-03-31 |
2023-08-12 |
mouse |
| Nicolas Kunz, Emily Jane Camm, Emmanuel Somm, Gregory Lodygensky, Stéphanie Darbre, Michel Lucien Aubert, Petra Susan Hüppi, Stéphane Vladimir Sizonenko, Rolf Gruette. Developmental and metabolic brain alterations in rats exposed to bisphenol A during gestation and lactation. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 29. issue 1. 2011-03-31. PMID:20955774. |
localized proton magnetic resonance spectroscopy ((1)h mrs) showed in the bpa-exposed rat a significant increase in glutamate concentration in the hippocampus as well as in the glu/asp ratio. |
2011-03-31 |
2023-08-12 |
rat |