| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fengling Pu, Tomohiro Kaneko, Makiko Enoki, Keiichi Irie, Takuya Okamoto, Yasuo Sei, Nobuaki Egashira, Ryozo Oishi, Kenichi Mishima, Hidetoshi Kamimura, Katsunori Iwasaki, Michihiro Fujiwar. Ameliorating effects of Kangen-karyu on neuronal damage in rats subjected to repeated cerebral ischemia. Journal of natural medicines. vol 64. issue 2. 2010-10-29. PMID:20155403. |
in vitro, kgkr (100-1000 microg/ml) dose-dependently suppressed hippocampal neuronal damage induced by both glutamate (100 microm) and kainate (1 mm). |
2010-10-29 |
2023-08-12 |
rat |
| Shan-xue Jin, Larry A Fei. Long-term potentiation in the CA1 hippocampus induced by NR2A subunit-containing NMDA glutamate receptors is mediated by Ras-GRF2/Erk map kinase signaling. PloS one. vol 5. issue 7. 2010-10-28. PMID:20661302. |
long-term potentiation in the ca1 hippocampus induced by nr2a subunit-containing nmda glutamate receptors is mediated by ras-grf2/erk map kinase signaling. |
2010-10-28 |
2023-08-12 |
Not clear |
| Yuki Kambe, Noritaka Nakamichi, Takeshi Takarada, Ryo Fukumori, Yukio Yoned. Induced tolerance to glutamate neurotoxicity through down-regulation of NR2 subunits of N-methyl-D-aspartate receptors in cultured rat striatal neurons. Journal of neuroscience research. vol 88. issue 10. 2010-10-26. PMID:20336776. |
we have previously shown differential vulnerabilities to glutamate (glu) excitotoxicity mediated by the n-methyl-d-aspartate (nmda) receptor (nmdar) between rat cortical and rat hippocampal neurons in culture. |
2010-10-26 |
2023-08-12 |
rat |
| Darin Edwards, Mainak Das, Peter Molnar, James J Hickma. Addition of glutamate to serum-free culture promotes recovery of electrical activity in adult hippocampal neurons in vitro. Journal of neuroscience methods. vol 190. issue 2. 2010-10-22. PMID:20452373. |
addition of glutamate to serum-free culture promotes recovery of electrical activity in adult hippocampal neurons in vitro. |
2010-10-22 |
2023-08-12 |
rat |
| Michaelangelo G Fuortes, Marjorie J Rico, Lisa R Merli. Distinctions between persistent and reversible group I mGluR-induced epileptiform burst prolongation. Epilepsia. vol 51. issue 8. 2010-10-22. PMID:20659148. |
we have previously shown that selective activation of group i metabotropic glutamate receptors (mglurs) results in long-lasting enhancement of synchronized network activity in the hippocampal slice. |
2010-10-22 |
2023-08-12 |
Not clear |
| Narinobu Juge, John A Gray, Hiroshi Omote, Takaaki Miyaji, Tsuyoshi Inoue, Chiaki Hara, Hisayuki Uneyama, Robert H Edwards, Roger A Nicoll, Yoshinori Moriyam. Metabolic control of vesicular glutamate transport and release. Neuron. vol 68. issue 1. 2010-10-22. PMID:20920794. |
consistent with these observations, acetoacetate reduced quantal size at hippocampal synapses and suppresses glutamate release and seizures evoked with 4-aminopyridine in the brain. |
2010-10-22 |
2023-08-12 |
Not clear |
| Yu-Zhen Pan, Linda Karr, Paul Ruteck. Ictal activity induced by group I metabotropic glutamate receptor activation and loss of afterhyperpolarizations. Neuropharmacology. vol 59. issue 1-2. 2010-10-20. PMID:20385148. |
exposure to the group i metabotropic glutamate receptor (mglur) agonist dihydroxyphenylglycine (dhpg) produces long-lasting changes in network excitability and epileptiform activity in the ca3 region of rat hippocampal slices that continues in the absence of the agonist and includes both interictal and more prolonged ictal-like activity. |
2010-10-20 |
2023-08-12 |
rat |
| Nora Laaris, Cameron H Good, Carl R Lupic. Delta9-tetrahydrocannabinol is a full agonist at CB1 receptors on GABA neuron axon terminals in the hippocampus. Neuropharmacology. vol 59. issue 1-2. 2010-10-20. PMID:20417220. |
cb1rs are found on glutamate and gaba neuron axon terminals in the hippocampus where they control neurotransmitter release. |
2010-10-20 |
2023-08-12 |
mouse |
| Nora Laaris, Cameron H Good, Carl R Lupic. Delta9-tetrahydrocannabinol is a full agonist at CB1 receptors on GABA neuron axon terminals in the hippocampus. Neuropharmacology. vol 59. issue 1-2. 2010-10-20. PMID:20417220. |
previous studies suggest that delta(9)-thc is a partial agonist of cb1rs on glutamate axon terminals in the hippocampus, whereas its effects on gaba terminals have not been described. |
2010-10-20 |
2023-08-12 |
mouse |
| Nora Laaris, Cameron H Good, Carl R Lupic. Delta9-tetrahydrocannabinol is a full agonist at CB1 receptors on GABA neuron axon terminals in the hippocampus. Neuropharmacology. vol 59. issue 1-2. 2010-10-20. PMID:20417220. |
furthermore, full agonist effects of delta(9)-thc on ipscs likely result from a much higher expression of cb1rs on gaba versus glutamate axon terminals in the hippocampus. |
2010-10-20 |
2023-08-12 |
mouse |
| Noritaka Nakamichi, Ryo Fukumori, Takeshi Takarada, Yuki Kambe, Tomomi Yamamoto, Nobuyuki Matsushima, Nobuaki Moriguchi, Yukio Yoned. Preferential inhibition by antidiarrheic 2-methoxy-4-methylphenol of Ca(2+) influx across acquired N-methyl-D-aspartate receptor channels composed of NR1/NR2B subunit assembly. Journal of neuroscience research. vol 88. issue 11. 2010-10-20. PMID:20623618. |
in our previous studies, particular phenolic ingredients, such as 2-methoxy-4-methylphenol (2m4mp), of the antidiarrheic drug wood creosote significantly prevented cell death by both hydrogen peroxide and glutamate in cultured rat hippocampal neurons. |
2010-10-20 |
2023-08-12 |
rat |
| Hua Sui, Xiao-Guang Lu, Li-Bin Zhan, Wan-Zhen Jiang, Xin Qi, Xiao-Yang Gong, Xin-Ping Ni. Decreased expression of spine-associated Rap guanosine triphosphatase-activating protein (SPAR) in glutamate-treated primary hippocampal neurons. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 17. issue 8. 2010-10-19. PMID:20547063. |
in the current study, we measured mrna and protein expression levels of spar and serum-inducible kinase (snk) in primary hippocampal neurons following glutamate treatment. |
2010-10-19 |
2023-08-12 |
Not clear |
| Hua Sui, Xiao-Guang Lu, Li-Bin Zhan, Wan-Zhen Jiang, Xin Qi, Xiao-Yang Gong, Xin-Ping Ni. Decreased expression of spine-associated Rap guanosine triphosphatase-activating protein (SPAR) in glutamate-treated primary hippocampal neurons. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 17. issue 8. 2010-10-19. PMID:20547063. |
expression of spar and snk was altered by glutamate treatment, indicating that the spar and snk signaling pathways may be involved in the damage to dendritic spines in hippocampal neurons following excitotoxicity induced by glutamate. |
2010-10-19 |
2023-08-12 |
Not clear |
| W Saskia van der Hel, Suzanne A M W Verlinde, Dimphna H M Meijer, Marina de Wit, Marije G Rensen, Koen L I van Gassen, Peter C van Rijen, Cees W M van Veelen, Pierre N E de Graa. Hippocampal distribution of vesicular glutamate transporter 1 in patients with temporal lobe epilepsy. Epilepsia. vol 50. issue 7. 2010-10-15. PMID:19389151. |
hippocampal distribution of vesicular glutamate transporter 1 in patients with temporal lobe epilepsy. |
2010-10-15 |
2023-08-12 |
human |
| Roelina Hagewoud, Robbert Havekes, Arianna Novati, Jan N Keijser, Eddy A Van der Zee, Peter Meerl. Sleep deprivation impairs spatial working memory and reduces hippocampal AMPA receptor phosphorylation. Journal of sleep research. vol 19. issue 2. 2010-10-08. PMID:20050994. |
in addition, we determined effects of sd on hippocampal glutamate alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptors and their regulatory pathways, which are crucially involved in working memory. |
2010-10-08 |
2023-08-12 |
mouse |
| Wei-Yi Ong, Ji-Hyun Kim, Xin He, Peng Chen, Akhlaq A Farooqui, Andrew M Jenne. Changes in brain cholesterol metabolome after excitotoxicity. Molecular neurobiology. vol 41. issue 2-3. 2010-10-08. PMID:20140539. |
intracerebroventricular injection of the potent glutamate analog kainate in rats results in increased cholesterol concentration in the hippocampus at short to medium time intervals, i.e., 3 days-1 week post-injection, as detected by gas chromatography-mass spectrometry in the lesioned hippocampus. |
2010-10-08 |
2023-08-12 |
rat |
| Claas Cassens, Ralf Kleene, Mei-Fang Xiao, Claudia Friedrich, Galina Dityateva, Claus Schafer-Nielsen, Melitta Schachne. Binding of the receptor tyrosine kinase TrkB to the neural cell adhesion molecule (NCAM) regulates phosphorylation of NCAM and NCAM-dependent neurite outgrowth. The Journal of biological chemistry. vol 285. issue 37. 2010-10-07. PMID:20605779. |
transfection of ncam-deficient hippocampal neurons with mutated ncam carrying an exchange of tyrosine by phenylalanine at position 734 leads to promotion of ncam-induced neurite outgrowth in comparison with that observed after transfection with wild-type ncam, whereas a reduction of neurite outgrowth was observed after transfection with mutated ncam, which carries an exchange of tyrosine by glutamate that mimics the phosphorylated tyrosine. |
2010-10-07 |
2023-08-12 |
Not clear |
| Dayan Knox, Shane A Perrine, Sophie A George, Matthew P Galloway, Israel Liberzo. Single prolonged stress decreases glutamate, glutamine, and creatine concentrations in the rat medial prefrontal cortex. Neuroscience letters. vol 480. issue 1. 2010-09-24. PMID:20546834. |
in order to address this, we used high-resolution magic angle spinning proton magnetic resonance spectroscopy (hr-mas (1)h mrs) ex vivo to assay levels of neurochemicals critical for energy metabolism (creatine and lactate), excitatory (glutamate and glutamine) and inhibitory (gamma amino butyric acid (gaba)) neurotransmission, and neuronal integrity (n-acetylaspartate (naa)) in the medial prefrontal cortex (mpfc), amygdala complex, and hippocampus of sps and control rats. |
2010-09-24 |
2023-08-12 |
rat |
| P A McCoy, L L McMaho. Sympathetic sprouting in visual cortex stimulated by cholinergic denervation rescues expression of two forms of long-term depression at layer 2/3 synapses. Neuroscience. vol 168. issue 3. 2010-09-21. PMID:20412838. |
several reports have shown that activation of muscarinic m1 receptors induces a long-term depression (mltd) at glutamate synapses in hippocampus and in several areas of cortex, including perirhinal and visual cortices. |
2010-09-21 |
2023-08-12 |
Not clear |
| Michelle C Potter, Greg I Elmer, Richard Bergeron, Edson X Albuquerque, Paolo Guidetti, Hui-Qiu Wu, Robert Schwarc. Reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 8. 2010-09-17. PMID:20336058. |
reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior. |
2010-09-17 |
2023-08-12 |
mouse |