| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Han-Seop Kim, Chang-Dae Bae, Joobae Par. Glutamate receptor-mediated phosphorylation of ezrin/radixin/moesin proteins is implicated in filopodial protrusion of primary cultured hippocampal neuronal cells. Journal of neurochemistry. vol 113. issue 6. 2010-08-06. PMID:20367752. |
previously, we reported the phosphorylation of moesin induced by electroconvulsive shock in rat brain and by glutamate in immortalized rat hippocampal cells. |
2010-08-06 |
2023-08-12 |
rat |
| Han-Seop Kim, Chang-Dae Bae, Joobae Par. Glutamate receptor-mediated phosphorylation of ezrin/radixin/moesin proteins is implicated in filopodial protrusion of primary cultured hippocampal neuronal cells. Journal of neurochemistry. vol 113. issue 6. 2010-08-06. PMID:20367752. |
in this study, we observed that glutamate induces phosphorylation of ezrin/radixin/moesin proteins (erm) in cultured hippocampal cells and that phosphorylated erm localizes at the newly formed filopodia of neurites. |
2010-08-06 |
2023-08-12 |
rat |
| Robert I Westphalen, Jieying Yu, Margarita Krivitski, Ting-Yu Jih, Hugh C Hemming. Regional differences in nerve terminal Na+ channel subtype expression and Na+ channel-dependent glutamate and GABA release in rat CNS. Journal of neurochemistry. vol 113. issue 6. 2010-08-06. PMID:20374421. |
na(v) coupling to transmitter release was determined by measuring the sensitivity of 4-aminopyridine (4ap)-evoked [(3)h]glutamate and [(14)c]gaba release to the specific na(v) blocker tetrodotoxin (ttx) for nerve terminals isolated from rat cerebral cortex, hippocampus, striatum and spinal cord. |
2010-08-06 |
2023-08-12 |
rat |
| Linda Karr, Yu-Zhen Pan, Paul A Ruteck. CB1 receptor antagonism impairs the induction of epileptiform activity by group I metabotropic glutamate receptor activation. Epilepsia. vol 51 Suppl 3. 2010-08-03. PMID:20618416. |
exposure to the group i metabotropic glutamate receptor (mglur) agonist dihydroxy phenylglycine (dhpg) induces epileptiform activity in the ca3 region of the hippocampus that persists following washout of dhpg. |
2010-08-03 |
2023-08-12 |
Not clear |
| Júlia D Moreira, Luisa Knorr, Marcelo Ganzella, Ana Paula Thomazi, Carolina G de Souza, Débora G de Souza, Carolina F Pitta, Tadeu Mello e Souza, Susana Wofchuk, Elaine Elisabetsky, Lúcia Vinadé, Marcos L S Perry, Diogo O Souz. Omega-3 fatty acids deprivation affects ontogeny of glutamatergic synapses in rats: relevance for behavior alterations. Neurochemistry international. vol 56. issue 6-7. 2010-07-29. PMID:20172010. |
additionally, hippocampal [(3)h]glutamate binding and uptake were assessed. |
2010-07-29 |
2023-08-12 |
rat |
| Adriana L Andrade, David J Ross. Simulated ischaemia induces Ca2+-independent glutamatergic vesicle release through actin filament depolymerization in area CA1 of the hippocampus. The Journal of physiology. vol 588. issue Pt 9. 2010-07-29. PMID:20211977. |
here we use simultaneous patch-clamp recording and ca(2+) imaging to monitor early changes in glutamate release and cytoplasmic [ca(2+)] ([ca(2+)](c)) in an in vitro slice model of hippocampal ischaemia. |
2010-07-29 |
2023-08-12 |
Not clear |
| Jie She. Impaired neurotransmitter release in Alzheimer's and Parkinson's diseases. Neuro-degenerative diseases. vol 7. issue 1-3. 2010-07-21. PMID:20173332. |
interestingly, our further genetic dissection in the hippocampal schaeffer collateral pathway highlighted the importance of presynaptic ps in the activity-dependent regulation of glutamate release and long-term potentiation induction via modulation of calcium release from intracellular stores. |
2010-07-21 |
2023-08-12 |
mouse |
| Ashok K Shetty, Bharathi Hattiangady, Muddanna S Ra. Vulnerability of hippocampal GABA-ergic interneurons to kainate-induced excitotoxic injury during old age. Journal of cellular and molecular medicine. vol 13. issue 8B. 2010-07-19. PMID:20141618. |
hippocampal inhibitory interneurons expressing glutamate decarboxylase-67 (gad-67) considerably decline in number during old age. |
2010-07-19 |
2023-08-12 |
rat |
| Randall L Woltjer, Kevin Duerson, Joseph M Fullmer, Paramita Mookherjee, Allison M Ryan, Thomas J Montine, Jeffrey A Kaye, Joseph F Quinn, Lisa Silbert, Deniz Erten-Lyons, James B Leverenz, Thomas D Bird, David V Pow, Kohichi Tanaka, G Stennis Watson, David G Coo. Aberrant detergent-insoluble excitatory amino acid transporter 2 accumulates in Alzheimer disease. Journal of neuropathology and experimental neurology. vol 69. issue 7. 2010-07-19. PMID:20535038. |
excitatory amino acid transporter 2 (eaat2) is the dominant glutamate transporter in cerebral cortex and hippocampus. |
2010-07-19 |
2023-08-12 |
human |
| Michael C Veronesi, Yanir Aldouby, Abraham J Domb, Michael J Kube. Thyrotropin-releasing hormone d,l polylactide nanoparticles (TRH-NPs) protect against glutamate toxicity in vitro and kindling development in vivo. Brain research. vol 1303. 2010-07-13. PMID:19766611. |
bioactivity/neuroprotection of d,l polylactide nanoparticles containing trh was assessed against glutamate toxicity in cultured rat fetal hippocampal neurons. |
2010-07-13 |
2023-08-12 |
human |
| Michele Bellesi, Fiorenzo Cont. The mGluR2/3 agonist LY379268 blocks the effects of GLT-1 upregulation on prepulse inhibition of the startle reflex in adult rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 6. 2010-07-12. PMID:20072121. |
recently, it has been shown that ceftriaxone (cef)-induced glt-1 upregulation is associated with an impairment of the prepulse inhibition (ppi) of the startle reflex, a simple form of information processing that is reduced in schizophrenia, and determines a strong reduction in hippocampal metabotropic glutamate receptor (mglur)2/3-dependent long-term depression. |
2010-07-12 |
2023-08-12 |
rat |
| Lei Chen, Haofei Wang, Zhuo Zhang, Zhen Li, Danjun He, Masahiro Sokabe, Ling Che. DMXB (GTS-21) ameliorates the cognitive deficits in beta amyloid(25-35(-) ) injected mice through preventing the dysfunction of alpha7 nicotinic receptor. Journal of neuroscience research. vol 88. issue 8. 2010-07-12. PMID:20127813. |
importantly, the treatment with dmxb (1 mg/kg) perfectly prevented abeta(25-35)-induced depression of alpha7nachr response, which was associated with improving the probability of presynaptic glutamate release and the induction of high-frequency stimulation (hfs)-dependent long-term potentiation (ltp) in hippocampal schaffer collaterale-ca1 synapse. |
2010-07-12 |
2023-08-12 |
mouse |
| A Tanti, C Belzun. Open questions in current models of antidepressant action. British journal of pharmacology. vol 159. issue 6. 2010-07-12. PMID:20132212. |
different symptomatic and pathophysiological features have been proposed as end points of the depressive phenotype and of the antidepressant action, including anhedonia, depressed mood, alterations in morphology and activity of some brain areas (amygdala, nucleus accumbens, hippocampus, prefrontal cortex and cingulate cortex), modifications in the connectivity between brain structures, changes in neurotransmitters (serotonin, noradrenaline, glutamate and neuropeptides), brain plasticity (neurogenesis, neurotrophins) and abnormal function of the hypothalamic-pituitary adrenal axis. |
2010-07-12 |
2023-08-12 |
Not clear |
| Alexandra L Ferguson, Trevor W Ston. Glutamate-induced depression of EPSP-spike coupling in rat hippocampal CA1 neurons and modulation by adenosine receptors. The European journal of neuroscience. vol 31. issue 7. 2010-07-01. PMID:20345917. |
in this study, glutamate was applied to hippocampal slices for several minutes, producing over-depolarization, which was reflected in an initial loss of evoked population potential size in the ca1 region. |
2010-07-01 |
2023-08-12 |
rat |
| Ana Ledo, Rui Barbosa, Enrique Cadenas, João Laranjinh. Dynamic and interacting profiles of *NO and O2 in rat hippocampal slices. Free radical biology & medicine. vol 48. issue 8. 2010-06-24. PMID:20100565. |
in the hippocampus, neuronal *no production is coupled to the activation of the nmda-type of glutamate receptor. |
2010-06-24 |
2023-08-12 |
rat |
| Tzu-Yu Lin, Cheng-Wei Lu, Wei-Jan Huang, Su-Jane Wan. Osthole or imperatorin-mediated facilitation of glutamate release is associated with a synaptic vesicle mobilization in rat hippocampal glutamatergic nerve endings. Synapse (New York, N.Y.). vol 64. issue 5. 2010-06-23. PMID:20034017. |
osthole or imperatorin-mediated facilitation of glutamate release is associated with a synaptic vesicle mobilization in rat hippocampal glutamatergic nerve endings. |
2010-06-23 |
2023-08-12 |
rat |
| Tzu-Yu Lin, Cheng-Wei Lu, Wei-Jan Huang, Su-Jane Wan. Osthole or imperatorin-mediated facilitation of glutamate release is associated with a synaptic vesicle mobilization in rat hippocampal glutamatergic nerve endings. Synapse (New York, N.Y.). vol 64. issue 5. 2010-06-23. PMID:20034017. |
osthole and imperatorin, two active compounds of cnidium monnieri (l.) cusson, have previously been shown to facilitate depolarization-evoked glutamate release from rat hippocampal nerve terminals by increasing voltage-dependent ca(2+) entry. |
2010-06-23 |
2023-08-12 |
rat |
| Tatiana Brustovetsky, Alexey Bolshakov, Nickolay Brustovetsk. Calpain activation and Na+/Ca2+ exchanger degradation occur downstream of calcium deregulation in hippocampal neurons exposed to excitotoxic glutamate. Journal of neuroscience research. vol 88. issue 6. 2010-06-22. PMID:19937813. |
calpain activation and na+/ca2+ exchanger degradation occur downstream of calcium deregulation in hippocampal neurons exposed to excitotoxic glutamate. |
2010-06-22 |
2023-08-12 |
Not clear |
| Lisa R Merli. The ups and downs of hippocampal metabotropic glutamate receptors: ramifications for epileptogenesis and cognitive impairment following status epilepticus. Epilepsy currents. vol 8. issue 2. 2010-06-18. PMID:18330467. |
the ups and downs of hippocampal metabotropic glutamate receptors: ramifications for epileptogenesis and cognitive impairment following status epilepticus. |
2010-06-18 |
2023-08-12 |
Not clear |
| Alexandre Loukanov, Naomi Kamasawa, Radostin Danev, Ryuichi Shigemoto, Kuniaki Nagayam. Immunolocalization of multiple membrane proteins on a carbon replica with STEM and EDX. Ultramicroscopy. vol 110. issue 4. 2010-06-18. PMID:20171011. |
this method was tested by observation of labeled ampa- and nmda-type glutamate receptors on sodium-dodecyl-sulfate-digested replica prepared from rat hippocampus. |
2010-06-18 |
2023-08-12 |
rat |