| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robert I Westphalen, No-Bong Kwak, Keir Daniels, Hugh C Hemming. Regional differences in the effects of isoflurane on neurotransmitter release. Neuropharmacology. vol 61. issue 4. 2012-05-25. PMID:21651920. |
isoflurane completely inhibited total 4ap-evoked glutamate release (ic(50) = 0.42 ± 0.03 mm) more potently than gaba release (ic(50) = 0.56 ± 0.02 mm) from cerebral cortex (1.3-fold greater potency), hippocampus and striatum, but inhibited glutamate and gaba release from spinal cord terminals equipotently. |
2012-05-25 |
2023-08-12 |
rat |
| Lech Kiedrowsk. Cytosolic acidification and intracellular zinc release in hippocampal neurons. Journal of neurochemistry. vol 121. issue 3. 2012-05-24. PMID:22339672. |
cultured hippocampal neurons were exposed to glutamate and glycine (glu/gly), while [zn²⁺](i), [ca²⁺](i) and ph(i) were monitored using fluozin-3, fura2-ff, and 2',7'-bis-(2-carboxyethyl)-5(6)-carboxyfluorescein, respectively. |
2012-05-24 |
2023-08-12 |
Not clear |
| E A Matveeva, D A Price, S W Whiteheart, T C Vanaman, G A Gerhardt, J T Slevi. Reduction of vesicle-associated membrane protein 2 expression leads to a kindling-resistant phenotype in a murine model of epilepsy. Neuroscience. vol 202. 2012-05-18. PMID:22183055. |
this report focuses on the effects that a ~50% reduction of synaptosomal vamp2 has on the progression of electrical kindling and on glutamate release in hippocampal subregions. |
2012-05-18 |
2023-08-12 |
mouse |
| E A Matveeva, D A Price, S W Whiteheart, T C Vanaman, G A Gerhardt, J T Slevi. Reduction of vesicle-associated membrane protein 2 expression leads to a kindling-resistant phenotype in a murine model of epilepsy. Neuroscience. vol 202. 2012-05-18. PMID:22183055. |
consistent with the expected effects of reducing a major neuronal v-snare, glutamate-selective, microelectrode array (mea) measurements in specific hippocampal subregions of vamp2(+/-) mice showed significant reductions in potassium-evoked glutamate release. |
2012-05-18 |
2023-08-12 |
mouse |
| João R Gomes, João T Costa, Carlos V Melo, Federico Felizzi, Patrícia Monteiro, Maria J Pinto, Ana R Inácio, Tadeusz Wieloch, Ramiro D Almeida, Mário Grãos, Carlos B Duart. Excitotoxicity downregulates TrkB.FL signaling and upregulates the neuroprotective truncated TrkB receptors in cultured hippocampal and striatal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 13. 2012-05-18. PMID:22457507. |
bdnf fully protected hippocampal neurons transduced with trkb.t when present during excitotoxic stimulation with glutamate, in contrast with the partial protection observed in cells overexpressing trkb.fl or expressing gfp. |
2012-05-18 |
2023-08-12 |
rat |
| Daniel Ortuño-Sahagún, Martha C Rivera-Cervantes, Graciela Gudiño-Cabrera, Felix Junyent, Ester Verdaguer, Carme Auladell, Mercè Pallàs, Antoni Camins, Carlos Beas-Zárat. Microarray analysis of rat hippocampus exposed to excitotoxicity: reversal Na(+)/Ca(2+) exchanger NCX3 is overexpressed in glial cells. Hippocampus. vol 22. issue 2. 2012-05-14. PMID:20928830. |
changes observed in gene expression induced by monosodium glutamate (msg) neonatal treatment in the hippocampus are consistent with the activation of the mechanisms that modulate nmda receptor function as well as with the implementation of plastic response to cell damage and intracellular calcium homeostasis. |
2012-05-14 |
2023-08-12 |
rat |
| Takeshi Uchida, Satoshi Fukuda, Haruyuki Kamiy. Heterosynaptic enhancement of the excitability of hippocampal mossy fibers by long-range spill-over of glutamate. Hippocampus. vol 22. issue 2. 2012-05-14. PMID:21049488. |
heterosynaptic enhancement of the excitability of hippocampal mossy fibers by long-range spill-over of glutamate. |
2012-05-14 |
2023-08-12 |
Not clear |
| Patricia Santofimia-Castaño, Gines M Salido, Antonio Gonzale. Ethanol reduces kainate-evoked glutamate secretion in rat hippocampal astrocytes. Brain research. vol 1402. 2012-05-14. PMID:21679931. |
ethanol reduces kainate-evoked glutamate secretion in rat hippocampal astrocytes. |
2012-05-14 |
2023-08-12 |
rat |
| Patricia Santofimia-Castaño, Gines M Salido, Antonio Gonzale. Ethanol reduces kainate-evoked glutamate secretion in rat hippocampal astrocytes. Brain research. vol 1402. 2012-05-14. PMID:21679931. |
in this study we have used rat hippocampal astrocytes in culture to investigate the effect of ethanol on kainate-induced glutamate secretion. |
2012-05-14 |
2023-08-12 |
rat |
| Patricia Santofimia-Castaño, Gines M Salido, Antonio Gonzale. Ethanol reduces kainate-evoked glutamate secretion in rat hippocampal astrocytes. Brain research. vol 1402. 2012-05-14. PMID:21679931. |
our results are consistent with an inhibitory action of ethanol on glutamate secretion from hippocampal astrocytes. |
2012-05-14 |
2023-08-12 |
rat |
| Patricia Santofimia-Castaño, Gines M Salido, Antonio Gonzale. Ethanol reduces kainate-evoked glutamate secretion in rat hippocampal astrocytes. Brain research. vol 1402. 2012-05-14. PMID:21679931. |
taking into account the pivotal role that astrocytes play within the central nervous system, especially in relation to neurons, the negative effects of ethanol on the release of glutamate might affect neuron-glia communication in the hippocampus, which might lead to functional defects in the brain. |
2012-05-14 |
2023-08-12 |
rat |
| Caroline Ménard, Rémi Quirio. Successful cognitive aging in rats: a role for mGluR5 glutamate receptors, homer 1 proteins and downstream signaling pathways. PloS one. vol 7. issue 1. 2012-05-14. PMID:22238580. |
at the molecular level, an increase in metabotropic glutamate receptors 5 (mglur5) was observed in post-synaptic densities (psd) in the hippocampus of au rats after training. |
2012-05-14 |
2023-08-12 |
rat |
| Bo Cui, Mingquan Wu, Xiaojun She, Hongtao Li. Impulse noise exposure in rats causes cognitive deficits and changes in hippocampal neurotransmitter signaling and tau phosphorylation. Brain research. vol 1427. 2012-05-11. PMID:22055774. |
effects of noise on the glutamate (glu)-n-methyl-d-aspartic acid receptor (nmdar) signaling system and hippocampal tau phosphorylation were investigated by high performance liquid chromatography, western blotting, and immunohistochemistry. |
2012-05-11 |
2023-08-12 |
rat |
| Jing Sun, Chang-kai Sun, Ming Fan, Ai-shi Ding, Lin Yin, Xiao-tong Wang, Wei W. [Effects of ginkgolide B against damage of cultured hippocampal neurons caused by glutamate]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 23. issue 2. 2012-04-30. PMID:21179757. |
[effects of ginkgolide b against damage of cultured hippocampal neurons caused by glutamate]. |
2012-04-30 |
2023-08-12 |
Not clear |
| Rodrigo S Sestito, Lucas B Trindade, Rodrigo G de Souza, Lucila N Kerbauy, Melina M Iyomasa, Maria L N M Ros. Effect of isolation rearing on the expression of AMPA glutamate receptors in the hippocampal formation. Journal of psychopharmacology (Oxford, England). vol 25. issue 12. 2012-04-26. PMID:20952455. |
the results suggest that isolation rearing from weaning induces changes on the expression of ampa glutamate receptors in the hippocampus similar to those reported for postmortem human brains with schizophrenia. |
2012-04-26 |
2023-08-12 |
human |
| Takeshi Kanno, Takahiro Yaguchi, Tetsu Nagata, Tadashi Shimizu, Akito Tanaka, Tomoyuki Nishizak. Indomethacin enhances learning and memory potential by interacting with CaMKII. Journal of cellular physiology. vol 227. issue 3. 2012-04-25. PMID:21503887. |
im (100 µm) significantly increased the rate of spontaneous ampa receptor-mediated miniature excitatory postsynaptic currents elicited from ca1 pyramidal neurons of rat hippocampal slices, without affecting the amplitude, and enhanced extracellular high k(+) (20 mm)-induced glutamate release from rat hippocampal slices, indicating that im stimulates presynaptic glutamate release. |
2012-04-25 |
2023-08-12 |
mouse |
| Takeshi Kanno, Takahiro Yaguchi, Tetsu Nagata, Tadashi Shimizu, Akito Tanaka, Tomoyuki Nishizak. Indomethacin enhances learning and memory potential by interacting with CaMKII. Journal of cellular physiology. vol 227. issue 3. 2012-04-25. PMID:21503887. |
the results of the present study indicate that im could enhance learning and memory potential by facilitating hippocampal synaptic transmission as a result from stimulating presynaptic glutamate release under the control of camkii. |
2012-04-25 |
2023-08-12 |
mouse |
| Larissa A Jarzylo, Heng-Ye Ma. Parasynaptic NMDA receptor signaling couples neuronal glutamate transporter function to AMPA receptor synaptic distribution and stability. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 7. 2012-04-23. PMID:22396428. |
using cultured hippocampal and cortical rat neurons, we show that inhibition of glutamate transporters leads to rapid reduction in ampar synaptic accumulation and total ampar abundance. |
2012-04-23 |
2023-08-12 |
rat |
| Hee-Yong Kim, Arthur A Spector, Zheng-Mei Xion. A synaptogenic amide N-docosahexaenoylethanolamide promotes hippocampal development. Prostaglandins & other lipid mediators. vol 96. issue 1-4. 2012-04-17. PMID:21810478. |
furthermore, dea stimulates neurite growth and synaptogenesis at substantially lower concentrations than dha, and it enhances glutamatergic synaptic activities with concomitant increases in synapsin and glutamate receptor subunit expression in the hippocampal neurons. |
2012-04-17 |
2023-08-12 |
mouse |
| Mohammed K Hankir, James R Parkinson, Stephen R Bloom, Jimmy D Bel. The effects of glutamate receptor agonists and antagonists on mouse hypothalamic and hippocampal neuronal activity shown through manganese enhanced MRI. NeuroImage. vol 59. issue 2. 2012-04-17. PMID:21925279. |
the effects of glutamate receptor agonists and antagonists on mouse hypothalamic and hippocampal neuronal activity shown through manganese enhanced mri. |
2012-04-17 |
2023-08-12 |
mouse |