| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elizabeth N Genda, Joshua G Jackson, Amanda L Sheldon, Susannah F Locke, Todd M Greco, John C O'Donnell, Lynn A Spruce, Rui Xiao, Wensheng Guo, Mary Putt, Steven Seeholzer, Harry Ischiropoulos, Michael B Robinso. Co-compartmentalization of the astroglial glutamate transporter, GLT-1, with glycolytic enzymes and mitochondria. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 50. 2012-02-09. PMID:22171032. |
acute inhibition of glycolysis or oxidative phosphorylation had no effect on glutamate uptake in hippocampal slices, but simultaneous inhibition of both processes significantly reduced transport. |
2012-02-09 |
2023-08-12 |
rat |
| Yuri Chihara, Yuto Ueda, Taku Doi, L James Willmor. Role of endoplasmic reticulum stress in the amygdaloid kindling model of rats. Neurochemical research. vol 36. issue 10. 2012-02-08. PMID:21604154. |
protein from ipsilateral hippocampus was electrophoresed on sds-page, followed by hybridization with primary antibodies, anti-kdel (-lys-asp-glu-coo-), bcl-2, bdnf (brain-derived neurotrophic factor), chop (c/ebp-homolog protein), c/ebp (ccaat/enhancer-binding protein), nmda (n-methyl-d-aspartate; -r1 &2a), glur1 (glutamate receptor), and β-tubulin. |
2012-02-08 |
2023-08-12 |
rat |
| Maurizio Popoli, Zhen Yan, Bruce S McEwen, Gerard Sanacor. The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission. Nature reviews. Neuroscience. vol 13. issue 1. 2012-02-07. PMID:22127301. |
mounting evidence suggests that acute and chronic stress, especially the stress-induced release of glucocorticoids, induces changes in glutamate neurotransmission in the prefrontal cortex and the hippocampus, thereby influencing some aspects of cognitive processing. |
2012-02-07 |
2023-08-12 |
Not clear |
| Ming Zhang, Ke Huang, Zhao Zhang, Baohu Ji, Hui Zhu, Kejun Zhou, Yang Li, Jinglei Yang, Liya Sun, Zhiyun Wei, Guang He, Linghan Gao, Lin He, Chunling Wa. Proteome alterations of cortex and hippocampus tissues in mice subjected to vitamin A depletion. The Journal of nutritional biochemistry. vol 22. issue 11. 2012-02-06. PMID:21190828. |
bioinformatic analysis using david revealed that altered proteins induced by vad showed significant enrichment of (i) glycolysis, cytoskeleton, mitochondrion and glutamate metabolism in the cortex; and (ii) actin binding, dopamine receptor signaling and transmission of nerve impulse in the hippocampus. |
2012-02-06 |
2023-08-12 |
mouse |
| Andrea C Lobo, João R Gomes, Tatiana Catarino, Miranda Mele, Pedro Fernandez, Ana R Inácio, Ben A Bahr, Armanda E Santos, Tadeusz Wieloch, Ana Luísa Carvalho, Carlos B Duart. Cleavage of the vesicular glutamate transporters under excitotoxic conditions. Neurobiology of disease. vol 44. issue 3. 2012-02-06. PMID:21807096. |
the results show that vglut2 is cleaved by calpains after excitotoxic stimulation of hippocampal neurons with glutamate, whereas vglut1 is downregulated to a lower extent. |
2012-02-06 |
2023-08-12 |
Not clear |
| E M Stanley, J R Fade. Aging-related alterations in orexin/hypocretin modulation of septo-hippocampal amino acid neurotransmission. Neuroscience. vol 195. 2012-02-06. PMID:21884758. |
here, orexin a (oxa) was administered to ca1 and the medial septum of young (3-4 months) and aged (27-29 months) fisher 344 brown norway rats, and hippocampal gaba and glutamate efflux was analyzed by in vivo microdialysis. |
2012-02-06 |
2023-08-12 |
rat |
| E M Stanley, J R Fade. Aging-related alterations in orexin/hypocretin modulation of septo-hippocampal amino acid neurotransmission. Neuroscience. vol 195. 2012-02-06. PMID:21884758. |
however, medial septum infusion of oxa did not impact hippocampal efflux in young rats, while aged rats exhibited a significant enhancement in gaba and glutamate efflux compared to young counterparts. |
2012-02-06 |
2023-08-12 |
rat |
| Alexander Zlotnik, Igor Sinelnikov, Benjamin F Gruenbaum, Shaun E Gruenbaum, Michael Dubilet, Elena Dubilet, Akiva Leibowitz, Sharon Ohayon, Adi Regev, Matthew Boyko, Yoram Shapira, Vivian I Teichber. Effect of glutamate and blood glutamate scavengers oxaloacetate and pyruvate on neurological outcome and pathohistology of the hippocampus after traumatic brain injury in rats. Anesthesiology. vol 116. issue 1. 2012-02-06. PMID:22129535. |
effect of glutamate and blood glutamate scavengers oxaloacetate and pyruvate on neurological outcome and pathohistology of the hippocampus after traumatic brain injury in rats. |
2012-02-06 |
2023-08-12 |
rat |
| Alexander Zlotnik, Igor Sinelnikov, Benjamin F Gruenbaum, Shaun E Gruenbaum, Michael Dubilet, Elena Dubilet, Akiva Leibowitz, Sharon Ohayon, Adi Regev, Matthew Boyko, Yoram Shapira, Vivian I Teichber. Effect of glutamate and blood glutamate scavengers oxaloacetate and pyruvate on neurological outcome and pathohistology of the hippocampus after traumatic brain injury in rats. Anesthesiology. vol 116. issue 1. 2012-02-06. PMID:22129535. |
the authors performed histologic studies of neuronal survival in the rat hippocampus after traumatic brain injury and treatment with blood glutamate scavengers. |
2012-02-06 |
2023-08-12 |
rat |
| Pirusha Ketheeswaranathan, Neil A Turner, Emma J Spary, Trevor F C Batten, Barry W McColl, Sikha Sah. Changes in glutamate transporter expression in mouse forebrain areas following focal ischemia. Brain research. vol 1418. 2012-01-30. PMID:21911209. |
this study used quantitative real-time reverse-transcription polymerase chain reaction to examine glutamate transporter mrna expression in the hippocampus, cortex and striatum in a mouse model of focal ischemic stroke induced by middle cerebral artery occlusion (mcao). |
2012-01-30 |
2023-08-12 |
mouse |
| Peter van der Sluijs, Casper C Hoogenraa. New insights in endosomal dynamics and AMPA receptor trafficking. Seminars in cell & developmental biology. vol 22. issue 5. 2012-01-26. PMID:21843653. |
the trafficking mechanisms that control the density of synaptic ampa-type glutamate receptors have received significant attention because of their importance for regulating excitatory synaptic transmission and synaptic plasticity in the hippocampus. |
2012-01-26 |
2023-08-12 |
Not clear |
| Xiangmin Peng, Jeeyong Kim, Zhigang Zhou, David J Fink, Marina Mat. Neuronal Nogo-A regulates glutamate receptor subunit expression in hippocampal neurons. Journal of neurochemistry. vol 119. issue 6. 2012-01-26. PMID:21985178. |
neuronal nogo-a regulates glutamate receptor subunit expression in hippocampal neurons. |
2012-01-26 |
2023-08-12 |
Not clear |
| Qian Tang, YinYin Xia, ShuQun Cheng, BaiJie T. Modulation of behavior and glutamate receptor mRNA expression in rats after sub-chronic administration of benzo(a)pyrene. Biomedical and environmental sciences : BES. vol 24. issue 4. 2012-01-26. PMID:22108330. |
the present study aimed to test whether exposure to benzo(a)pyrene [b(a)p] affects spatial learning and short-term memory by modulating the expression of the gria1 and grin2a glutamate receptor subunit genes in the hippocampus. |
2012-01-26 |
2023-08-12 |
rat |
| Rivelilson Mendes de Freitas, Fábio de Oliveira Silva, Gláucio Barros Saldanha, Joaquín Jordá. Lipoic acid alters amino acid neurotransmitters content in rat hippocampus after pilocarpine-induced seizures. Fundamental & clinical pharmacology. vol 25. issue 4. 2012-01-24. PMID:20636364. |
this study was aimed at investigating the anticonvulsant activity of lipoic acid (la) against pilocarpine-induced seizures as well as the effects of this metabolic antioxidant on the hippocampal extracellular concentrations of amino acid neurotransmitters glutamate, aspartate, glycine and glutamate and γ-aminobutyric acid (gaba). |
2012-01-24 |
2023-08-12 |
rat |
| Rivelilson Mendes de Freitas, Fábio de Oliveira Silva, Gláucio Barros Saldanha, Joaquín Jordá. Lipoic acid alters amino acid neurotransmitters content in rat hippocampus after pilocarpine-induced seizures. Fundamental & clinical pharmacology. vol 25. issue 4. 2012-01-24. PMID:20636364. |
in vivo microdialysis demonstrated that an intraperitoneal administration of pilocarpine induced a pronounced increment of hippocampal glutamate and aspartate concentrations, whereas no significant change was observed in the levels of glycine or gaba. |
2012-01-24 |
2023-08-12 |
rat |
| Rivelilson Mendes de Freitas, Fábio de Oliveira Silva, Gláucio Barros Saldanha, Joaquín Jordá. Lipoic acid alters amino acid neurotransmitters content in rat hippocampus after pilocarpine-induced seizures. Fundamental & clinical pharmacology. vol 25. issue 4. 2012-01-24. PMID:20636364. |
significant reductions in hippocampal gaba and glycine concentrations were also observed although not as pronounced as those shown by glutamate and aspartate. |
2012-01-24 |
2023-08-12 |
rat |
| Mathias Zink, Thomas Ferbert, Stefanie T Frank, Patricia Seufert, Peter J Gebicke-Haerter, Rainer Spanage. Perinatal exposure to alcohol disturbs spatial learning and glutamate transmission-related gene expression in the adult hippocampus. The European journal of neuroscience. vol 34. issue 3. 2012-01-23. PMID:21722212. |
perinatal exposure to alcohol disturbs spatial learning and glutamate transmission-related gene expression in the adult hippocampus. |
2012-01-23 |
2023-08-12 |
rat |
| Mathias Zink, Thomas Ferbert, Stefanie T Frank, Patricia Seufert, Peter J Gebicke-Haerter, Rainer Spanage. Perinatal exposure to alcohol disturbs spatial learning and glutamate transmission-related gene expression in the adult hippocampus. The European journal of neuroscience. vol 34. issue 3. 2012-01-23. PMID:21722212. |
this specific learning deficit was accompanied by a dysregulation in hippocampal gene expression (significant induction of vesicular glutamate transporter 1, eaat1, eaat3, nr2a, 2b, 2c and 2d). |
2012-01-23 |
2023-08-12 |
rat |
| Haitham S Mohammed, Heba S Aboul Ezz, Yasser A Khadrawy, Neveen A Noo. Neurochemical and electrophysiological changes induced by paradoxical sleep deprivation in rats. Behavioural brain research. vol 225. issue 1. 2012-01-18. PMID:21729722. |
the amino acid neurotransmitter analysis revealed a significant increase in cortical glutamate, glycine and taurine levels while in the hippocampus, glutamate, aspartate, glutamine and glycine levels increased significantly. |
2012-01-18 |
2023-08-12 |
rat |
| Meagan L Wisniewski, Jeannie Hwang, Ben A Bah. Submicromolar Aβ42 reduces hippocampal glutamate receptors and presynaptic markers in an aggregation-dependent manner. Biochimica et biophysica acta. vol 1812. issue 12. 2012-01-17. PMID:21978994. |
submicromolar aβ42 reduces hippocampal glutamate receptors and presynaptic markers in an aggregation-dependent manner. |
2012-01-17 |
2023-08-12 |
Not clear |