| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rong Yang, Rong Zhou, Lei Chen, Weiyan Cai, Hidekazu Tomimoto, Masahiro Sokabe, Ling Che. Pregnenolone sulfate enhances survival of adult-generated hippocampal granule cells via sustained presynaptic potentiation. Neuropharmacology. vol 60. issue 2-3. 2011-11-22. PMID:21111750. |
hippocampal slices, which were prepared 60 min after the in vivo pregs-injection and followed by 60 min perfusion with artificial cerebrospinal fluid (acsf), showed a sustained (>60 min) increase in the presynaptic glutamate release at perforant path-granule cell synapses. |
2011-11-22 |
2023-08-12 |
mouse |
| Júlia D Moreira, Letícia V de Siqueira, Vanessa M Lague, Lisiane O Porciúncula, Lúcia Vinadé, Diogo O Souz. Short-term alterations in hippocampal glutamate transport system caused by one-single neonatal seizure episode: implications on behavioral performance in adulthood. Neurochemistry international. vol 59. issue 2. 2011-11-22. PMID:21693144. |
short-term alterations in hippocampal glutamate transport system caused by one-single neonatal seizure episode: implications on behavioral performance in adulthood. |
2011-11-22 |
2023-08-12 |
rat |
| Júlia D Moreira, Letícia V de Siqueira, Vanessa M Lague, Lisiane O Porciúncula, Lúcia Vinadé, Diogo O Souz. Short-term alterations in hippocampal glutamate transport system caused by one-single neonatal seizure episode: implications on behavioral performance in adulthood. Neurochemistry international. vol 59. issue 2. 2011-11-22. PMID:21693144. |
in this study, alterations in the hippocampal glutamate transporters activity and immunocontent were investigated in neonatal rats (7 days old) submitted to kainate-induced seizures model. |
2011-11-22 |
2023-08-12 |
rat |
| Júlia D Moreira, Letícia V de Siqueira, Vanessa M Lague, Lisiane O Porciúncula, Lúcia Vinadé, Diogo O Souz. Short-term alterations in hippocampal glutamate transport system caused by one-single neonatal seizure episode: implications on behavioral performance in adulthood. Neurochemistry international. vol 59. issue 2. 2011-11-22. PMID:21693144. |
glutamate uptake, glutamate transporters (glt-1, glast, eaac1) and glutamine synthetase (gs) were assessed in hippocampal slices obtained 12 h, 24 h, 48 h, 72 h and 60 days after seizures. |
2011-11-22 |
2023-08-12 |
rat |
| Júlia D Moreira, Letícia V de Siqueira, Vanessa M Lague, Lisiane O Porciúncula, Lúcia Vinadé, Diogo O Souz. Short-term alterations in hippocampal glutamate transport system caused by one-single neonatal seizure episode: implications on behavioral performance in adulthood. Neurochemistry international. vol 59. issue 2. 2011-11-22. PMID:21693144. |
the decrease on glutamate uptake was observed in hippocampal slices obtained 24 h after seizures. |
2011-11-22 |
2023-08-12 |
rat |
| Júlia D Moreira, Letícia V de Siqueira, Vanessa M Lague, Lisiane O Porciúncula, Lúcia Vinadé, Diogo O Souz. Short-term alterations in hippocampal glutamate transport system caused by one-single neonatal seizure episode: implications on behavioral performance in adulthood. Neurochemistry international. vol 59. issue 2. 2011-11-22. PMID:21693144. |
our findings indicate that acute modifications on hippocampal glutamate transporters triggered by a single convulsive event in early life may play a role in the behavioral alterations observed in adulthood. |
2011-11-22 |
2023-08-12 |
rat |
| E Vazquez-Valls, M E Flores-Soto, V Chaparro-Huerta, B M Torres-Mendoza, G Gudiño-Cabrera, M C Rivera-Cervantes, M Pallas, A Camins, J Armendáriz-Borunda, C Beas-Zarat. HIF-1α expression in the hippocampus and peripheral macrophages after glutamate-induced excitotoxicity. Journal of neuroimmunology. vol 238. issue 1-2. 2011-11-22. PMID:21807419. |
in addition, vegf expression was increased in neurons and over-expressed in glial cells in a model of neuroexcitotoxicity in the hippocampus, in which rats were neonatally exposed to high glutamate concentrations. |
2011-11-22 |
2023-08-12 |
rat |
| Peter Cook, Colleen Reichmuth, Frances Gullan. Rapid behavioural diagnosis of domoic acid toxicosis in California sea lions. Biology letters. vol 7. issue 4. 2011-11-21. PMID:21389016. |
exposure to high doses of domoic acid, a glutamate agonist, may lead to persistent medial temporal seizures and damage to the hippocampus. |
2011-11-21 |
2023-08-12 |
human |
| A Galanopoulos, A Polissidis, Z Papadopoulou-Daifoti, G G Nomikos, K Antonio. Δ(9)-THC and WIN55,212-2 affect brain tissue levels of excitatory amino acids in a phenotype-, compound-, dose-, and region-specific manner. Behavioural brain research. vol 224. issue 1. 2011-11-21. PMID:21645556. |
the aim of the present study was to investigate the effects of the cannabinoid agonists, Δ(9)-thc and win55,212-2, on tissue (prefrontal cortex, dorsal striatum, nucleus accumbens, hippocampus, amygdala and hypothalamus) levels of glutamate and aspartate in two rat phenotypes, high responders (hr) and low responders (lr), differentiated according to their response to a novel environment. |
2011-11-21 |
2023-08-12 |
rat |
| A Galanopoulos, A Polissidis, Z Papadopoulou-Daifoti, G G Nomikos, K Antonio. Δ(9)-THC and WIN55,212-2 affect brain tissue levels of excitatory amino acids in a phenotype-, compound-, dose-, and region-specific manner. Behavioural brain research. vol 224. issue 1. 2011-11-21. PMID:21645556. |
the cannabinoids primarily increased glutamate levels in the prefrontal cortex, dorsal striatum, nucleus accumbens and hippocampus, while the high dose of win55,212-2 decreased glutamate levels in the amygdala and both doses in the hypothalamus; these effects appeared overall more pronounced in hr. |
2011-11-21 |
2023-08-12 |
rat |
| Roopali Yadav, Ronald Rimerman, Margaret A Scofield, Shashank M Dravi. Mutations in the transmembrane domain M3 generate spontaneously open orphan glutamate δ1 receptor. Brain research. vol 1382. 2011-11-15. PMID:21215726. |
glutamate delta-1 receptors (glurδ1) are expressed in the adult hippocampus and inner ear and have recently been shown to be important for high-frequency hearing. |
2011-11-15 |
2023-08-12 |
Not clear |
| Priyanka Rao-Ruiz, Diana C Rotaru, Rolinka J van der Loo, Huibert D Mansvelder, Oliver Stiedl, August B Smit, Sabine Spijke. Retrieval-specific endocytosis of GluA2-AMPARs underlies adaptive reconsolidation of contextual fear. Nature neuroscience. vol 14. issue 10. 2011-11-15. PMID:21909089. |
here we show that retrieval of fear memory induces a biphasic temporal change in glua2-containing ampa-type glutamate receptor (ampar) membrane expression and synaptic strength in the mouse dorsal hippocampus. |
2011-11-15 |
2023-08-12 |
mouse |
| Vasco C Sousa, Natália Assaife-Lopes, Joaquim A Ribeiro, Judith A Pratt, Ros R Brett, Ana M Sebastiã. Regulation of hippocampal cannabinoid CB1 receptor actions by adenosine A1 receptors and chronic caffeine administration: implications for the effects of Δ9-tetrahydrocannabinol on spatial memory. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 2. 2011-11-14. PMID:20927050. |
we first tested the hypothesis that an a(1)-cb(1) interaction influences gaba and glutamate release in the hippocampus. |
2011-11-14 |
2023-08-12 |
mouse |
| Vasco C Sousa, Natália Assaife-Lopes, Joaquim A Ribeiro, Judith A Pratt, Ros R Brett, Ana M Sebastiã. Regulation of hippocampal cannabinoid CB1 receptor actions by adenosine A1 receptors and chronic caffeine administration: implications for the effects of Δ9-tetrahydrocannabinol on spatial memory. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 2. 2011-11-14. PMID:20927050. |
this study shows that a(1) receptors exert a negative modulatory effect on cb(1)-mediated inhibition of gaba and glutamate release, and provides the first evidence of chronic caffeine-induced alterations on the cannabinoid system in the cortex and hippocampus, with functional implications in spatial memory. |
2011-11-14 |
2023-08-12 |
mouse |
| Pauline Sousa dos Santos, Lidianne Mayra Lopes Campêlo, Rizângela Lyne Mendes de Freitas, Chistiane Mendes Feitosa, Gláucio Barros Saldanha, Rivelilson Mendes de Freita. Lipoic acid effects on glutamate and taurine concentrations in rat hippocampus after pilocarpine-induced seizures. Arquivos de neuro-psiquiatria. vol 69. issue 2B. 2011-11-08. PMID:21625766. |
lipoic acid effects on glutamate and taurine concentrations in rat hippocampus after pilocarpine-induced seizures. |
2011-11-08 |
2023-08-12 |
rat |
| Pauline Sousa dos Santos, Lidianne Mayra Lopes Campêlo, Rizângela Lyne Mendes de Freitas, Chistiane Mendes Feitosa, Gláucio Barros Saldanha, Rivelilson Mendes de Freita. Lipoic acid effects on glutamate and taurine concentrations in rat hippocampus after pilocarpine-induced seizures. Arquivos de neuro-psiquiatria. vol 69. issue 2B. 2011-11-08. PMID:21625766. |
the objective of the present study was to evaluate the lipoic acid (la) effects in glutamate and taurine contents in rat hippocampus after pilocarpine-induced seizures. |
2011-11-08 |
2023-08-12 |
rat |
| Pauline Sousa dos Santos, Lidianne Mayra Lopes Campêlo, Rizângela Lyne Mendes de Freitas, Chistiane Mendes Feitosa, Gláucio Barros Saldanha, Rivelilson Mendes de Freita. Lipoic acid effects on glutamate and taurine concentrations in rat hippocampus after pilocarpine-induced seizures. Arquivos de neuro-psiquiatria. vol 69. issue 2B. 2011-11-08. PMID:21625766. |
in pilocarpine group, it was observed a significant increase in glutamate content (37%) and a decrease in taurine level (18%) in rat hippocampus, when compared to control group. |
2011-11-08 |
2023-08-12 |
rat |
| Pauline Sousa dos Santos, Lidianne Mayra Lopes Campêlo, Rizângela Lyne Mendes de Freitas, Chistiane Mendes Feitosa, Gláucio Barros Saldanha, Rivelilson Mendes de Freita. Lipoic acid effects on glutamate and taurine concentrations in rat hippocampus after pilocarpine-induced seizures. Arquivos de neuro-psiquiatria. vol 69. issue 2B. 2011-11-08. PMID:21625766. |
antioxidant pretreatment significantly reduced the glutamate level (28%) and augmented taurine content (32%) in rat hippocampus, when compared to pilocarpine group. |
2011-11-08 |
2023-08-12 |
rat |
| Jing Chen, Kao-Wei Chua, Chu C Chua, Hailong Yu, Aijie Pei, Balvin H L Chua, Ronald C Hamdy, Xingshun Xu, Chun-Feng Li. Antioxidant activity of 7,8-dihydroxyflavone provides neuroprotection against glutamate-induced toxicity. Neuroscience letters. vol 499. issue 3. 2011-11-07. PMID:21651962. |
previous studies have shown that excess glutamate can cause oxidative stress in a hippocampal ht-22 cell line. |
2011-11-07 |
2023-08-12 |
Not clear |
| Jiajia Yang, Lei An, Yang Yao, Zhuo Yang, Tao Zhan. Melamine impairs spatial cognition and hippocampal synaptic plasticity by presynaptic inhibition of glutamatergic transmission in infant rats. Toxicology. vol 289. issue 2-3. 2011-11-02. PMID:21867740. |
in conclusion, melamine reduced the release of glutamate in presynaptic transmission of hippocampus, which partly resulted in diminished ltp and further damaged the function of learning and memory. |
2011-11-02 |
2023-08-12 |
rat |