| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Dal-Cim, W C Martins, A R S Santos, C I Tasc. Guanosine is neuroprotective against oxygen/glucose deprivation in hippocampal slices via large conductance Ca²+-activated K+ channels, phosphatidilinositol-3 kinase/protein kinase B pathway activation and glutamate uptake. Neuroscience. vol 183. 2011-08-26. PMID:21435378. |
guanosine is neuroprotective against oxygen/glucose deprivation in hippocampal slices via large conductance ca²+-activated k+ channels, phosphatidilinositol-3 kinase/protein kinase b pathway activation and glutamate uptake. |
2011-08-26 |
2023-08-12 |
rat |
| T Dal-Cim, W C Martins, A R S Santos, C I Tasc. Guanosine is neuroprotective against oxygen/glucose deprivation in hippocampal slices via large conductance Ca²+-activated K+ channels, phosphatidilinositol-3 kinase/protein kinase B pathway activation and glutamate uptake. Neuroscience. vol 183. 2011-08-26. PMID:21435378. |
hippocampal slices subjected to ogd and re-oxygenation showed a significant reduction of glutamate uptake. |
2011-08-26 |
2023-08-12 |
rat |
| Marija V Turovskaya, Egor A Turovsky, Valery P Zinchenko, Sergei G Levin, Alina A Shamsutdinova, Oleg V Godukhi. Repeated brief episodes of hypoxia modulate the calcium responses of ionotropic glutamate receptors in hippocampal neurons. Neuroscience letters. vol 496. issue 1. 2011-08-26. PMID:21458539. |
repeated brief episodes of hypoxia modulate the calcium responses of ionotropic glutamate receptors in hippocampal neurons. |
2011-08-26 |
2023-08-12 |
rat |
| Marija V Turovskaya, Egor A Turovsky, Valery P Zinchenko, Sergei G Levin, Alina A Shamsutdinova, Oleg V Godukhi. Repeated brief episodes of hypoxia modulate the calcium responses of ionotropic glutamate receptors in hippocampal neurons. Neuroscience letters. vol 496. issue 1. 2011-08-26. PMID:21458539. |
the aim of this study was to evaluate the intracellular cytosolic calcium concentration ([ca(2+)](i)) changes induced by activation of ionotropic glutamate receptors in cultured hippocampal neurons after repeated brief episodes of hypoxia. |
2011-08-26 |
2023-08-12 |
rat |
| Marija V Turovskaya, Egor A Turovsky, Valery P Zinchenko, Sergei G Levin, Alina A Shamsutdinova, Oleg V Godukhi. Repeated brief episodes of hypoxia modulate the calcium responses of ionotropic glutamate receptors in hippocampal neurons. Neuroscience letters. vol 496. issue 1. 2011-08-26. PMID:21458539. |
the main result of our study is that brief hypoxic episodes progressively depress the [ca(2+)](i) increases induced by agonists of ampa and nmda glutamate receptors in cultured hippocampal neurons. |
2011-08-26 |
2023-08-12 |
rat |
| R Rupsingh, M Borrie, M Smith, J L Wells, R Barth. Reduced hippocampal glutamate in Alzheimer disease. Neurobiology of aging. vol 32. issue 5. 2011-08-17. PMID:19501936. |
reduced hippocampal glutamate in alzheimer disease. |
2011-08-17 |
2023-08-12 |
human |
| Michelle L Stephens, Jorge E Quintero, Francois Pomerleau, Peter Huettl, Greg A Gerhard. Age-related changes in glutamate release in the CA3 and dentate gyrus of the rat hippocampus. Neurobiology of aging. vol 32. issue 5. 2011-08-17. PMID:19535175. |
age-related changes in glutamate release in the ca3 and dentate gyrus of the rat hippocampus. |
2011-08-17 |
2023-08-12 |
rat |
| Michelle L Stephens, Jorge E Quintero, Francois Pomerleau, Peter Huettl, Greg A Gerhard. Age-related changes in glutamate release in the CA3 and dentate gyrus of the rat hippocampus. Neurobiology of aging. vol 32. issue 5. 2011-08-17. PMID:19535175. |
the present studies employed a novel microelectrode array recording technology to study glutamate release and uptake in the dentate gyrus, ca3 and ca1 hippocampal subregions in anesthetized young, late-middle aged and aged male fischer 344 rats. |
2011-08-17 |
2023-08-12 |
rat |
| Michelle L Stephens, Jorge E Quintero, Francois Pomerleau, Peter Huettl, Greg A Gerhard. Age-related changes in glutamate release in the CA3 and dentate gyrus of the rat hippocampus. Neurobiology of aging. vol 32. issue 5. 2011-08-17. PMID:19535175. |
taken together, these data support dynamic changes to glutamate regulation during aging in subregions of the mammalian hippocampus that are critical for learning and memory. |
2011-08-17 |
2023-08-12 |
rat |
| Ana Paula S de Vasconcellos-Bittencourt, Deusa Aparecida Vendite, Melissa Nassif, Leonardo M Crema, Rudimar Frozza, Ana Paula Thomazi, Fabiane B Nieto, Susana Wofchuk, Christianne Salbego, Elizabete Rocha da Rocha, Carla Dalma. Chronic stress and lithium treatments alter hippocampal glutamate uptake and release in the rat and potentiate necrotic cellular death after oxygen and glucose deprivation. Neurochemical research. vol 36. issue 5. 2011-08-16. PMID:21253855. |
chronic stress and lithium treatments alter hippocampal glutamate uptake and release in the rat and potentiate necrotic cellular death after oxygen and glucose deprivation. |
2011-08-16 |
2023-08-12 |
rat |
| Ana Paula S de Vasconcellos-Bittencourt, Deusa Aparecida Vendite, Melissa Nassif, Leonardo M Crema, Rudimar Frozza, Ana Paula Thomazi, Fabiane B Nieto, Susana Wofchuk, Christianne Salbego, Elizabete Rocha da Rocha, Carla Dalma. Chronic stress and lithium treatments alter hippocampal glutamate uptake and release in the rat and potentiate necrotic cellular death after oxygen and glucose deprivation. Neurochemical research. vol 36. issue 5. 2011-08-16. PMID:21253855. |
we observed an increased synaptosomal [(3)h]glutamate uptake and an increase in [(3)h]glutamate stimulated release in hippocampus of lithium-treated rats. |
2011-08-16 |
2023-08-12 |
rat |
| Ana Paula S de Vasconcellos-Bittencourt, Deusa Aparecida Vendite, Melissa Nassif, Leonardo M Crema, Rudimar Frozza, Ana Paula Thomazi, Fabiane B Nieto, Susana Wofchuk, Christianne Salbego, Elizabete Rocha da Rocha, Carla Dalma. Chronic stress and lithium treatments alter hippocampal glutamate uptake and release in the rat and potentiate necrotic cellular death after oxygen and glucose deprivation. Neurochemical research. vol 36. issue 5. 2011-08-16. PMID:21253855. |
chronic stress increased basal [(3)h]glutamate release by synaptosomes, and decreased [(3)h]glutamate uptake in hippocampal slices. |
2011-08-16 |
2023-08-12 |
rat |
| Sâmia Regiane L Joca, Cláudia Maria Padovan, Francisco Silveira Guimarãe. [Stress, depression and the hippocampus]. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). vol 25 Suppl 2. 2011-08-15. PMID:14978587. |
antidepressive drugs attenuate these effects, probably by increasing the expression of neurotrophic factors; 2. facilitation of serotonergic neurotransmission in the hippocampus attenuates behavioral consequences of stress and produce antidepressive-like effects in several animal models; 3. antagonism of glutamate, the main excitatory neurotransmitter of the hippocampus, also induce antidepressive-like effects; 4. increased hippocampal activity has been described in genetically selected rats that are more sensitive to depression models. |
2011-08-15 |
2023-08-12 |
rat |
| Helena Domin, Barbara Zięba, Krystyna Gołembiowska, Magdalena Kowalska, Anna Dziubina, Maria Śmiałowsk. Neuroprotective potential of mGluR5 antagonist MTEP: effects on kainate-induced excitotoxicity in the rat hippocampus. Pharmacological reports : PR. vol 62. issue 6. 2011-08-10. PMID:21273662. |
the study was also aimed at determining a possible influence of mtep on neuronal glutamate release induced by ka in the hippocampus, using microdialysis method. |
2011-08-10 |
2023-08-12 |
rat |
| Helena Domin, Barbara Zięba, Krystyna Gołembiowska, Magdalena Kowalska, Anna Dziubina, Maria Śmiałowsk. Neuroprotective potential of mGluR5 antagonist MTEP: effects on kainate-induced excitotoxicity in the rat hippocampus. Pharmacological reports : PR. vol 62. issue 6. 2011-08-10. PMID:21273662. |
moreover, it was observed that mtep significantly reduced the ka-induced glutamate release in the hippocampus. |
2011-08-10 |
2023-08-12 |
rat |
| Anneleen Schallier, Ilse Smolders, Debby Van Dam, Ellen Loyens, Peter Paul De Deyn, Alex Michotte, Yvette Michotte, Ann Massi. Region- and age-specific changes in glutamate transport in the AβPP23 mouse model for Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 24. issue 2. 2011-08-04. PMID:21297271. |
transporter expression was studied in cortical and hippocampal tissue and linked to extracellular glutamate and glutamate reuptake activity as measured using in vivo microdialysis. |
2011-08-04 |
2023-08-12 |
mouse |
| Binbin Qian, Yajie Sun, Zhen Wu, Li Wan, Lulan Chen, Shuzhen Kong, Binhong Zhang, Fayong Zhang, Zhen-Yu Wang, Yun Wan. Epileptiform response of CA1 neurones to convulsant stimulation by cyclothiazide, kainic acid and pentylenetetrazol in anaesthetized rats. Seizure. vol 20. issue 4. 2011-08-03. PMID:21269843. |
in conclusion, ctz and ptz induced epileptiform activities are most likely to share a similar progressive pattern in hippocampus with gabaergic mechanism dominant in epileptogenesis, while ctz model involves additional glutamate receptor activation. |
2011-08-03 |
2023-08-12 |
rat |
| Filipa I Baptista, Joana M Gaspar, Armando Cristóvão, Paulo F Santos, Attila Köfalvi, António F Ambrósi. Diabetes induces early transient changes in the content of vesicular transporters and no major effects in neurotransmitter release in hippocampus and retina. Brain research. vol 1383. 2011-08-02. PMID:21281613. |
in this study, we evaluated the effect of diabetes (two and eight weeks duration) on basal and evoked release of [(14)c]glutamate and [(3)h]gaba in hippocampal and retinal synaptosomes. |
2011-08-02 |
2023-08-12 |
Not clear |
| Filipa I Baptista, Joana M Gaspar, Armando Cristóvão, Paulo F Santos, Attila Köfalvi, António F Ambrósi. Diabetes induces early transient changes in the content of vesicular transporters and no major effects in neurotransmitter release in hippocampus and retina. Brain research. vol 1383. 2011-08-02. PMID:21281613. |
the protein content of vesicular glutamate and gaba transporters, and of the α(1a) subunit, was differently affected by diabetes in hippocampal and retinal synaptosomes. |
2011-08-02 |
2023-08-12 |
Not clear |
| Filipa I Baptista, Joana M Gaspar, Armando Cristóvão, Paulo F Santos, Attila Köfalvi, António F Ambrósi. Diabetes induces early transient changes in the content of vesicular transporters and no major effects in neurotransmitter release in hippocampus and retina. Brain research. vol 1383. 2011-08-02. PMID:21281613. |
after eight weeks of diabetes, the basal release of glutamate slightly increased in hippocampus and the evoked gaba release decreased in retina. |
2011-08-02 |
2023-08-12 |
Not clear |