| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christine M Wroge, Joshua Hogins, Larry Eisenman, Steven Menneric. Synaptic NMDA receptors mediate hypoxic excitotoxic death. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 19. 2012-07-06. PMID:22573696. |
in rat hippocampal neurons, we found that a neuroprotective concentration of memantine shows little selectivity for extrasynaptic nmdars when all receptors are tonically activated by exogenous glutamate. |
2012-07-06 |
2023-08-12 |
rat |
| Ana Cristina Guerra Souza, Carmine Inês Acker, Bibiana Mozzaquatro Gai, José Sebastião dos Santos Neto, Cristina Wayne Nogueir. 2-phenylethynyl-butyltellurium improves memory in mice. Neurochemistry international. vol 60. issue 4. 2012-07-05. PMID:22285151. |
moreover, the involvement of glutamate uptake and release in cerebral cortex and hippocampus of mice was investigated. |
2012-07-05 |
2023-08-12 |
mouse |
| Ana Cristina Guerra Souza, Carmine Inês Acker, Bibiana Mozzaquatro Gai, José Sebastião dos Santos Neto, Cristina Wayne Nogueir. 2-phenylethynyl-butyltellurium improves memory in mice. Neurochemistry international. vol 60. issue 4. 2012-07-05. PMID:22285151. |
the [(3)h]glutamate uptake by cerebral cortex and hippocampal slices of mice was significantly inhibited after 1h of treatment with pebt. |
2012-07-05 |
2023-08-12 |
mouse |
| Ana Cristina Guerra Souza, Carmine Inês Acker, Bibiana Mozzaquatro Gai, José Sebastião dos Santos Neto, Cristina Wayne Nogueir. 2-phenylethynyl-butyltellurium improves memory in mice. Neurochemistry international. vol 60. issue 4. 2012-07-05. PMID:22285151. |
after 24h of pebt exposure, only the hippocampal [(3)h]glutamate uptake was inhibited. |
2012-07-05 |
2023-08-12 |
mouse |
| Ana Cristina Guerra Souza, Carmine Inês Acker, Bibiana Mozzaquatro Gai, José Sebastião dos Santos Neto, Cristina Wayne Nogueir. 2-phenylethynyl-butyltellurium improves memory in mice. Neurochemistry international. vol 60. issue 4. 2012-07-05. PMID:22285151. |
the [(3)h]glutamate release by cerebral cortex and hippocampal synaptosomes of mice was not altered. |
2012-07-05 |
2023-08-12 |
mouse |
| R A Mohamed, A M Agha, N N Nassa. SCH58261 the selective adenosine A(2A) receptor blocker modulates ischemia reperfusion injury following bilateral carotid occlusion: role of inflammatory mediators. Neurochemical research. vol 37. issue 3. 2012-06-29. PMID:22071908. |
ir increased hippocampal glutamate (glu), gaba, glycine (gly) and aspartate (asp). |
2012-06-29 |
2023-08-12 |
rat |
| Patricia Salazar, Ricardo Tapi. Allopregnanolone potentiates the glutamate-mediated seizures induced by 4-aminopyridine in rat hippocampus in vivo. Neurochemical research. vol 37. issue 3. 2012-06-29. PMID:22081320. |
we previously found that in rat hippocampal slices allopregnanolone (3α-hydroxy-5α-pregnan-20-one), a positive gaba(a) receptor modulator, suppresses the epileptic discharges induced by 4-aminopyridine (4-ap), a convulsant k(+) channel blocker that stimulates glutamate release. |
2012-06-29 |
2023-08-12 |
rat |
| Patricia Salazar, Ricardo Tapi. Allopregnanolone potentiates the glutamate-mediated seizures induced by 4-aminopyridine in rat hippocampus in vivo. Neurochemical research. vol 37. issue 3. 2012-06-29. PMID:22081320. |
extracellular levels of aspartate, glutamate and gaba were analyzed by hplc in the microdialysis fractions, and 24 h after the experiment the hippocampus was studied histologically. |
2012-06-29 |
2023-08-12 |
rat |
| Guangliang Cao, Minxia Gu, Min Zhu, Junying Gao, Ying Yin, Charles Marshall, Ming Xiao, Jiong Ding, Dengshun Mia. Bmi-1 absence causes premature brain degeneration. PloS one. vol 7. issue 2. 2012-06-29. PMID:22363787. |
moreover, astroglial glutamate transporters and glutamine synthetase decreased in the bmi-1 null hippocampus, which might contribute to the sporadic epileptic-like seizures in these mice. |
2012-06-29 |
2023-08-12 |
mouse |
| Jae-Wook Kim, Chung-Soo Kim, Zhenzhen Hu, Jin-Yi Han, Si Kwan Kim, Sung-Kwang Yoo, Yeong Man Yeo, Myong Soo Chong, Kinam Lee, Jin Tae Hong, Ki-Wan O. Enhancement of pentobarbital-induced sleep by apigenin through chloride ion channel activation. Archives of pharmacal research. vol 35. issue 2. 2012-06-26. PMID:22370792. |
apigenin increased glutamate decarboxylase (gad) and had no effect on the expression of gaba(a) receptor α-, β-, γ-subunits in n hippocampus of mouse brain, showing different expression of subunits from pentobarbital treatment group. |
2012-06-26 |
2023-08-12 |
mouse |
| T A Antipova, T A Gudasheva, S B Seredeni. In vitro study of neuroprotective properties of GK-2, a new original nerve growth factor mimetic. Bulletin of experimental biology and medicine. vol 150. issue 5. 2012-06-25. PMID:22235396. |
new nerve growth factor (ngf) mimetic gk-2, a substituted dimeric dipeptide, in a concentration of up to 10(-9)m produced a protective effect on the culture of immortalized mouse hippocampal neurons (line ht-22) after addition of h(2)o(2)and glutamate. |
2012-06-25 |
2023-08-12 |
mouse |
| Alfred Meurs, Jeanelle Portelli, Ralph Clinckers, Ambikaipakan Balasubramaniam, Yvette Michotte, Ilse Smolder. Neuropeptide Y increases in vivo hippocampal extracellular glutamate levels through Y1 receptor activation. Neuroscience letters. vol 510. issue 2. 2012-06-25. PMID:22285263. |
neuropeptide y increases in vivo hippocampal extracellular glutamate levels through y1 receptor activation. |
2012-06-25 |
2023-08-12 |
rat |
| Alfred Meurs, Jeanelle Portelli, Ralph Clinckers, Ambikaipakan Balasubramaniam, Yvette Michotte, Ilse Smolder. Neuropeptide Y increases in vivo hippocampal extracellular glutamate levels through Y1 receptor activation. Neuroscience letters. vol 510. issue 2. 2012-06-25. PMID:22285263. |
to date no study has attempted to investigate the effect of npy in vivo on extracellular (ec) glutamate levels thus, via intracerebral microdialysis, we determined npy's effect on hippocampal glutamate concentrations in vivo, and consequently the involvement of y(1) receptors to this effect. |
2012-06-25 |
2023-08-12 |
rat |
| Alfred Meurs, Jeanelle Portelli, Ralph Clinckers, Ambikaipakan Balasubramaniam, Yvette Michotte, Ilse Smolder. Neuropeptide Y increases in vivo hippocampal extracellular glutamate levels through Y1 receptor activation. Neuroscience letters. vol 510. issue 2. 2012-06-25. PMID:22285263. |
npy or the y(1) agonist d-his26-npy was intrahippocampally administered in rats for 2h, during which the hippocampal glutamate dialysate levels were monitored. |
2012-06-25 |
2023-08-12 |
rat |
| Alfred Meurs, Jeanelle Portelli, Ralph Clinckers, Ambikaipakan Balasubramaniam, Yvette Michotte, Ilse Smolder. Neuropeptide Y increases in vivo hippocampal extracellular glutamate levels through Y1 receptor activation. Neuroscience letters. vol 510. issue 2. 2012-06-25. PMID:22285263. |
hippocampal y(1) receptor blockade prevented the npy-induced increase in hippocampal glutamate, proving that this induced glutamate increase is clearly y(1) receptor mediated. |
2012-06-25 |
2023-08-12 |
rat |
| Alfred Meurs, Jeanelle Portelli, Ralph Clinckers, Ambikaipakan Balasubramaniam, Yvette Michotte, Ilse Smolder. Neuropeptide Y increases in vivo hippocampal extracellular glutamate levels through Y1 receptor activation. Neuroscience letters. vol 510. issue 2. 2012-06-25. PMID:22285263. |
this is the first evidence that npy enhances hippocampal ec glutamate overflow in vivo via hippocampal y(1) receptors without interfering with or contributing to npy's anticonvulsant effect. |
2012-06-25 |
2023-08-12 |
rat |
| Jin-Yong Park, Nelson Sprusto. Synergistic actions of metabotropic acetylcholine and glutamate receptors on the excitability of hippocampal CA1 pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 18. 2012-06-25. PMID:22553015. |
here, we show, using whole-cell recordings in rat hippocampal slices, that group i metabotropic glutamate receptors (mglurs) and muscarinic acetylcholine receptors (machrs) synergistically increase the excitability of hippocampal ca1 pyramidal neurons by converting the post-burst afterhyperpolarization to an afterdepolarization via a rapidly reversible upregulation of ca(v)2.3 r-type calcium channels. |
2012-06-25 |
2023-08-12 |
rat |
| Israeli Ran, Isabel Laplante, Jean-Claude Lacaill. CREB-dependent transcriptional control and quantal changes in persistent long-term potentiation in hippocampal interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 18. 2012-06-25. PMID:22553039. |
a transcription- and translation-dependent form of long-term potentiation was uncovered at excitatory synapses onto hippocampal interneurons in oriens-alveus (oa-ins) which is induced by activation of type 1 metabotropic glutamate receptors (cl-ltp(mglur1)). |
2012-06-25 |
2023-08-12 |
rat |
| Konstantinos Sarantis, Katerina Antoniou, Nikolaos Matsokis, Fevronia Angelato. Exposure to novel environment is characterized by an interaction of D1/NMDA receptors underlined by phosphorylation of the NMDA and AMPA receptor subunits and activation of ERK1/2 signaling, leading to epigenetic changes and gene expression in rat hippocampus. Neurochemistry international. vol 60. issue 1. 2012-06-20. PMID:22080157. |
interactions between dopamine and glutamate receptors are essential for prefrontal cortical (pfc) and hippocampal cognitive functions. |
2012-06-20 |
2023-08-12 |
rat |
| Enikö A Kramár, Lulu Y Chen, Julie C Lauterborn, Danielle A Simmons, Christine M Gall, Gary Lync. BDNF upregulation rescues synaptic plasticity in middle-aged ovariectomized rats. Neurobiology of aging. vol 33. issue 4. 2012-06-15. PMID:20674095. |
comparable rescue results were obtained after elevating endogenous bdnf protein levels in hippocampus with 4 daily injections of a short half-life ampakine (positive modulator of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate [ampa]-type glutamate receptors). |
2012-06-15 |
2023-08-12 |
human |