| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Francisco E Olucha-Bordonau, Marcos Otero-García, Ana M Sánchez-Pérez, Angel Núñez, Sherie Ma, Andrew L Gundlac. Distribution and targets of the relaxin-3 innervation of the septal area in the rat. The Journal of comparative neurology. vol 520. issue 9. 2012-08-27. PMID:22134882. |
in the medial septum, we observed relaxin-3-immunoreactive contacts with chat-, pv-, and glutamate decarboxylase-67-positive neurons that projected to hippocampus, and contacts between relaxin-3 terminals and calbindin- and calretinin-positive neurons. |
2012-08-27 |
2023-08-12 |
rat |
| Renaud Greget, Fabien Pernot, Jean-Marie C Bouteiller, Viviane Ghaderi, Sushmita Allam, Anne Florence Keller, Nicolas Ambert, Arnaud Legendre, Merdan Sarmis, Olivier Haeberle, Michel Faupel, Serge Bischoff, Theodore W Berger, Michel Baudr. Simulation of postsynaptic glutamate receptors reveals critical features of glutamatergic transmission. PloS one. vol 6. issue 12. 2012-08-27. PMID:22194830. |
activation of several subtypes of glutamate receptors contributes to changes in postsynaptic calcium concentration at hippocampal synapses, resulting in various types of changes in synaptic strength. |
2012-08-27 |
2023-08-12 |
Not clear |
| Lasse Ormel, Mats Julius Stensrud, Linda Hildegard Bergersen, Vidar Gunderse. VGLUT1 is localized in astrocytic processes in several brain regions. Glia. vol 60. issue 2. 2012-08-24. PMID:22009457. |
by confocal microscopy, the authors, in this study, show that vesicles by a family of glutamate transporters 1 (vglut1) labeling was clearly present within astrocytic processes (diameter > 1 μm) in several brain regions; the dentate-molecular layers, the stratum radiatum of ca1 hippocampus, the frontal cortex, and the striatum. |
2012-08-24 |
2023-08-12 |
Not clear |
| Lasse Ormel, Mats Julius Stensrud, Linda Hildegard Bergersen, Vidar Gunderse. VGLUT1 is localized in astrocytic processes in several brain regions. Glia. vol 60. issue 2. 2012-08-24. PMID:22009457. |
the authors have concluded that astrocytes not only in the dentate-molecular layers but also in stratum radiatum of ca1 hippocampus, frontal cortex, and the striatum possess slmvs carrying vglut1, suggesting that astrocytes in all these brain regions are capable of vesicular release of glutamate. |
2012-08-24 |
2023-08-12 |
Not clear |
| Julia Langer, Jonathan Stephan, Martin Theis, Christine R Ros. Gap junctions mediate intercellular spread of sodium between hippocampal astrocytes in situ. Glia. vol 60. issue 2. 2012-08-24. PMID:22025386. |
in contrast to results obtained earlier in cultured astrocytes, our data thus indicate that calcium signaling and metabotropic glutamate receptors are supportive of, but not prerequisites for, the spread of sodium between hippocampal astrocytes in situ, whereas expression of cx30 and cx43 is essential. |
2012-08-24 |
2023-08-12 |
mouse |
| Adrienne M Benediktsson, Glen S Marrs, Jian Cheng Tu, Paul F Worley, Jeffrey D Rothstein, Dwight E Bergles, Michael E Daile. Neuronal activity regulates glutamate transporter dynamics in developing astrocytes. Glia. vol 60. issue 2. 2012-08-24. PMID:22052455. |
here, we examined the subcellular distribution and dynamic remodeling of the predominant glut glt-1 (excitatory amino acid transporter 2, eaat2) in developing hippocampal astrocytes. |
2012-08-24 |
2023-08-12 |
Not clear |
| Jin-Hee Sung, Myeong-Ok Kim, Phil-Ok Ko. Ferulic acid attenuates the focal cerebral ischemic injury-induced decrease in parvalbumin expression. Neuroscience letters. vol 516. issue 1. 2012-08-24. PMID:22490888. |
in cultured hippocampal cells, glutamate toxicity significantly increased the intracellular ca(2+) concentration, whereas this increase in ca(2+) levels was inhibited by ferulic acid treatment. |
2012-08-24 |
2023-08-12 |
rat |
| Teresita L Briones, Magdalena Rogozinska, Julie Wood. Modulation of ischemia-induced NMDAR1 activation by environmental enrichment decreases oxidative damage. Journal of neurotrauma. vol 28. issue 12. 2012-08-23. PMID:21612313. |
our data showed that glutamate receptor expression was significantly higher in the hippocampus of the ischemia con group than in the ischemia ee group. |
2012-08-23 |
2023-08-12 |
rat |
| Dayne Beccano-Kelly, Jenni Harve. Leptin: a novel therapeutic target in Alzheimer's disease? International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22254146. |
in particular, recent studies have highlighted a potential cognitive enhancing role for leptin as it regulates diverse aspects of hippocampal synaptic function that are thought to underlie learning and memory processes including glutamate receptor trafficking, dendritic morphology, and activity-dependent synaptic plasticity. |
2012-08-23 |
2023-08-12 |
Not clear |
| Daniel J Kanak, Ryan T Jones, Ashish Tokhi, Amy L Willingham, Hitten P Zaveri, Gregory M Rose, Peter R Patryl. Electrical and Pharmacological Stimuli Reveal a Greater Susceptibility for CA3 Network Excitability in Hippocampal Slices from Aged vs. Adult Fischer 344 Rats. Aging and disease. vol 2. issue 4. 2012-08-23. PMID:22396884. |
clinical data and experimental studies in rats have shown that the aged cns is more susceptible to the proconvulsive effects of the excitotoxic glutamate analogues kainate (ka) and domoate (da), which bind high-affinity receptors localized at mossy fiber (mf) synapses in the ca3 subregion of the hippocampus. |
2012-08-23 |
2023-08-12 |
rat |
| Karim Le Meur, Juan Mendizabal-Zubiaga, Pedro Grandes, Etienne Audina. GABA release by hippocampal astrocytes. Frontiers in computational neuroscience. vol 6. 2012-08-23. PMID:22912614. |
the relevance of the astrocytic release of gaba, and glutamate, on the physiopathology of the hippocampus remains to be established. |
2012-08-23 |
2023-08-12 |
rat |
| F A Moreira, D C Aguiar, L B Resstel, S F Lisboa, A C Campos, F V Gomes, F S Guimarãe. Neuroanatomical substrates involved in cannabinoid modulation of defensive responses. Journal of psychopharmacology (Oxford, England). vol 26. issue 1. 2012-08-21. PMID:21616976. |
the present review summarizes recent data suggesting that they involve modulation of glutamate and gaba-mediated neurotransmission in brain sites such as the medial prefrontal cortex, amygdaloid complex, bed nucleus of the stria terminalis, hippocampus and dorsal periaqueductal gray. |
2012-08-21 |
2023-08-12 |
Not clear |
| Rong-Fang Feng, Wen-Bin Li, Hui-Qing Liu, Qing-Jun Li, Xiao-Ling Chen, Ai-Min Zhou, Hong-Gang Zhao, Jie A. [Effects of alpha-methyl-(4-tetrazolyl-phenyl) glycine on the induction of hippocampal ischemic tolerance in the rat]. Sheng li xue bao : [Acta physiologica Sinica]. vol 55. issue 3. 2012-08-20. PMID:12817298. |
to explore the role of metabotropic glutamate receptor 2/3 mglur 2/3 in the induction of brain ischemic tolerance (bit), the influences of mglur2/3 antagonist alpha-methyl-(4-tetrazolyl-phenyl) glycine (mtpg) on the induction of bit and expression of glial fibrillary acidic protein (gfap) in the hippocampus were observed using thionin staining and gfap immunohistochemical staining in a rat brain ischemic model with four-vessel occlusion (4vo). |
2012-08-20 |
2023-08-12 |
rat |
| Ethel Antunes Wilhelm, Bibiana Mozzaquatro Gai, Ana Cristina Guerra Souza, Cristiani Folharini Bortolatto, Juliano Alex Roehrs, Cristina Wayne Nogueir. Involvement of GABAergic and glutamatergic systems in the anticonvulsant activity of 3-alkynyl selenophene in 21 day-old rats. Molecular and cellular biochemistry. vol 365. issue 1-2. 2012-08-20. PMID:22350757. |
), and [(3)h]γ-aminobutyric acid (gaba) and [(3)h]glutamate uptakes were carried out in slices of cerebral cortex and hippocampus. |
2012-08-20 |
2023-08-12 |
rat |
| Ethel Antunes Wilhelm, Bibiana Mozzaquatro Gai, Ana Cristina Guerra Souza, Cristiani Folharini Bortolatto, Juliano Alex Roehrs, Cristina Wayne Nogueir. Involvement of GABAergic and glutamatergic systems in the anticonvulsant activity of 3-alkynyl selenophene in 21 day-old rats. Molecular and cellular biochemistry. vol 365. issue 1-2. 2012-08-20. PMID:22350757. |
in contrast, no alteration was observed in [(3)h]glutamate uptake in cerebral cortex and hippocampus slices of 21 day-old rats that received 3-asp. |
2012-08-20 |
2023-08-12 |
rat |
| Zhengtao Hu, Yi Deng, Chunyan Hu, Pengchi Deng, Qian Bu, Guangyan Yan, Jiaqing Zhou, Xue Shao, Jinxuan Zhao, Yan Li, Ruiming Zhu, Youzhi Xu, Yinglan Zhao, Xiaobo Ce. ¹H NMR-based metabonomic analysis of brain in rats of morphine dependence and withdrawal intervention. Behavioural brain research. vol 231. issue 1. 2012-08-20. PMID:22391120. |
we found that the concentrations of neurotransmitters including glutamate, glutamine and gamma-aminobutyric acid changed differentially in hippocampus, nac, pfc and striatum after repeated morphine treatment. |
2012-08-20 |
2023-08-12 |
rat |
| Fabrício Luiz Assini, Carina Akemi Nakamura, Tetsade Camboim Piermartiri, Carla Inês Tasca, Reinaldo Naoto Takahash. Coadministration of cannabinoid CB1-receptor and adenosine A1-receptor antagonists improves the acquisition of spatial memory in mice: participation of glutamatergic neurotransmission. Behavioural pharmacology. vol 23. issue 3. 2012-08-20. PMID:22495186. |
moreover, this drug combination induced a significant ex-vivo enhancement in glutamate release into hippocampal slices. |
2012-08-20 |
2023-08-12 |
mouse |
| Ming Zhou, Casper C Hoogenraad, Marian Joëls, Harm J Kruger. Combined β-adrenergic and corticosteroid receptor activation regulates AMPA receptor function in hippocampal neurons. Journal of psychopharmacology (Oxford, England). vol 26. issue 4. 2012-08-17. PMID:21965192. |
since both noradrenaline and corticosterone are known to quickly affect properties of ampa-type glutamate receptors (ampar), we here examined - in hippocampal neurons - three parameters which give insight in the functionality of ampars: phosphorylation, surface expression and spontaneous synaptic transmission. |
2012-08-17 |
2023-08-12 |
Not clear |
| J Lewerenz, H Sato, P Albrecht, N Henke, R Noack, A Methner, P Mahe. Mutation of ATF4 mediates resistance of neuronal cell lines against oxidative stress by inducing xCT expression. Cell death and differentiation. vol 19. issue 5. 2012-08-17. PMID:22095285. |
we recently reported that in hippocampal ht22 cells selected for resistance against oxidative glutamate toxicity, the cystine/glutamate antiporter system x(c)(-), which imports cystine for synthesis of the antioxidant glutathione, and its specific subunit, xct, are upregulated. |
2012-08-17 |
2023-08-12 |
Not clear |
| Louisa Lyon, Philip W J Burnet, James N C Kew, Corrado Corti, J Nicholas P Rawlins, Tracy Lane, Bianca De Filippis, Paul J Harrison, David M Bannerma. Fractionation of spatial memory in GRM2/3 (mGlu2/mGlu3) double knockout mice reveals a role for group II metabotropic glutamate receptors at the interface between arousal and cognition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 13. 2012-08-14. PMID:21832989. |
group ii metabotropic glutamate receptors (mglur2 and mglur3, encoded by grm2 and grm3) are implicated in hippocampal function and cognition, and in the pathophysiology and treatment of schizophrenia and other psychiatric disorders. |
2012-08-14 |
2023-08-12 |
mouse |