| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emily M Stanley, Marlene A Wilson, Jim R Fade. Hippocampal neurotransmitter efflux during one-trial novel object recognition in rats. Neuroscience letters. vol 511. issue 1. 2012-07-27. PMID:22306091. |
these data suggest that the hippocampus, and in particular, hippocampal glutamate, may be involved in memory processes during novelty recognition paradigms. |
2012-07-27 |
2023-08-12 |
rat |
| Pontus Wasling, Joakim Strandberg, Eric Hans. AMPA receptor activation causes silencing of AMPA receptor-mediated synaptic transmission in the developing hippocampus. PloS one. vol 7. issue 4. 2012-07-27. PMID:22485173. |
here we show that the agonist ampa causes a depression of ampa receptor (ampar) signaling at glutamate synapses in the ca1 region of the hippocampus in slices from developing, but not from mature, rats. |
2012-07-27 |
2023-08-12 |
rat |
| Slavica Krantic, Nathalie Isorce, Naguib Mechawar, Maria Antonietta Davoli, Erika Vignault, Marilia Albuquerque, Jean-Guy Chabot, Emmanuel Moyse, Jean-Pierre Chauvin, Isabelle Aubert, Joanne McLaurin, Rémi Quirio. Hippocampal GABAergic neurons are susceptible to amyloid-β toxicity in vitro and are decreased in number in the Alzheimer's disease TgCRND8 mouse model. Journal of Alzheimer's disease : JAD. vol 29. issue 2. 2012-07-26. PMID:22232004. |
in the tgcrnd8 mouse model of ad, we found a significant decrease in the number of hippocampal neurons immunoreactive for glutamate decarboxylase 67 (gad67), the enzyme synthesizing gaba. |
2012-07-26 |
2023-08-12 |
mouse |
| Yuxia Xu, Motoki Tanaka, Ling Chen, Masahiro Sokab. DHEAS induces short-term potentiation via the activation of a metabotropic glutamate receptor in the rat hippocampus. Hippocampus. vol 22. issue 4. 2012-07-24. PMID:21484933. |
dheas induces short-term potentiation via the activation of a metabotropic glutamate receptor in the rat hippocampus. |
2012-07-24 |
2023-08-12 |
rat |
| Günther Sperk, Anna Wieselthaler-Hölzl, Susanne Pirker, Ramon Tasan, Sarah S Strasser, Meinrad Drexel, Christian Pifl, Julian Marschalek, Martin Ortler, Eugen Trinka, Katja Heitmair-Wietzorrek, Philippe Ciofi, Martha Feucht, Christoph Baumgartner, Thomas Czec. Glutamate decarboxylase 67 is expressed in hippocampal mossy fibers of temporal lobe epilepsy patients. Hippocampus. vol 22. issue 3. 2012-07-23. PMID:21509853. |
glutamate decarboxylase 67 is expressed in hippocampal mossy fibers of temporal lobe epilepsy patients. |
2012-07-23 |
2023-08-12 |
rat |
| Günther Sperk, Anna Wieselthaler-Hölzl, Susanne Pirker, Ramon Tasan, Sarah S Strasser, Meinrad Drexel, Christian Pifl, Julian Marschalek, Martin Ortler, Eugen Trinka, Katja Heitmair-Wietzorrek, Philippe Ciofi, Martha Feucht, Christoph Baumgartner, Thomas Czec. Glutamate decarboxylase 67 is expressed in hippocampal mossy fibers of temporal lobe epilepsy patients. Hippocampus. vol 22. issue 3. 2012-07-23. PMID:21509853. |
recently, expression of glutamate decarboxylase-67 (gad67), a key enzyme of gaba synthesis, was detected in the otherwise glutamatergic mossy fibers of the rat hippocampus. |
2012-07-23 |
2023-08-12 |
rat |
| Maria Śmiałowska, Krystyna Gołembiowska, Małgorzata Kajta, Barbara Zięba, Anna Dziubina, Helena Domi. Selective mGluR1 antagonist EMQMCM inhibits the kainate-induced excitotoxicity in primary neuronal cultures and in the rat hippocampus. Neurotoxicity research. vol 21. issue 4. 2012-07-23. PMID:22144346. |
in vivo microdialysis studies in rat hippocampus showed that emqmcm (100 μm) significantly increased γ-aminobutyric acid (gaba) and decreased glutamate release. |
2012-07-23 |
2023-08-12 |
mouse |
| Eva Martisova, Maite Solas, Igor Horrillo, Jorge E Ortega, J Javier Meana, Rosa María Tordera, María Javier Ramíre. Long lasting effects of early-life stress on glutamatergic/GABAergic circuitry in the rat hippocampus. Neuropharmacology. vol 62. issue 5-6. 2012-07-23. PMID:22245561. |
aged ms rats showed a downregulation of vesicular glutamate transporter 1 and 2 (vglut1 and vglut2) and gaba transporter (vgat) and increased expression of excitatory amino acid transporter 2 (eaat2) in the hippocampus. |
2012-07-23 |
2023-08-12 |
rat |
| Eva Martisova, Maite Solas, Igor Horrillo, Jorge E Ortega, J Javier Meana, Rosa María Tordera, María Javier Ramíre. Long lasting effects of early-life stress on glutamatergic/GABAergic circuitry in the rat hippocampus. Neuropharmacology. vol 62. issue 5-6. 2012-07-23. PMID:22245561. |
corticosterone induced an increase glutamate and a decrease in gaba release in hippocampal slices, which was reversed by venlafaxine. |
2012-07-23 |
2023-08-12 |
rat |
| S Babic, M Ondrejcakova, J Bakos, E Racekova, D Jezov. Cell proliferation in the hippocampus and in the heart is modified by exposure to repeated stress and treatment with memantine. Journal of psychiatric research. vol 46. issue 4. 2012-07-20. PMID:22297273. |
the present studies were aimed to verify the hypothesis that treatment with memantine, a low affinity nmda glutamate receptor antagonist, can reduce possible stress-induced alterations in cell proliferation in the hippocampus and in the heart and has consequences on stress hormone release. |
2012-07-20 |
2023-08-12 |
rat |
| Mital Bhadania, Hanumanthachar Joshi, Purva Patel, Venkatrao H Kulkarn. Protective effect of menthol on β-amyloid peptide induced cognitive deficits in mice. European journal of pharmacology. vol 681. issue 1-3. 2012-07-20. PMID:22329901. |
it is suggested that a selective decrease in hippocampal glutamate concentration may account for deterioration in learning and memory process, considering the important role of this neurotransmitter in the cognitive functions. |
2012-07-20 |
2023-08-12 |
mouse |
| Yukitoshi Izumi, Charles F Zorumsk. NMDA receptors, mGluR5, and endocannabinoids are involved in a cascade leading to hippocampal long-term depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 3. 2012-07-19. PMID:21993209. |
in the ca1 region of the rat hippocampus, metabotropic glutamate receptor-5 (mglur5) and cannabinoid-1 receptors (cb1rs) are believed to participate in long-term synaptic depression (ltd). |
2012-07-19 |
2023-08-12 |
rat |
| H K Sreepathi, F Ferragut. Subpopulations of neurokinin 1 receptor-expressing neurons in the rat lateral amygdala display a differential pattern of innervation from distinct glutamatergic afferents. Neuroscience. vol 203. 2012-07-19. PMID:22210508. |
by using a dual immunoperoxidase/immunogold-silver procedure at the ultrastructural level, we found that in la ~75% of glutamatergic synapses onto nk1-expressing neurons were labeled for the vesicular glutamate transporter 1 indicating that they most likely are of cortical, hippocampal, or intrinsic origin. |
2012-07-19 |
2023-08-12 |
rat |
| Jean-Baptiste Drouet, Florence Fauvelle, Cécile Batandier, André Peinnequin, Antonia Alonso, Nadine Fidier, Renaud Maury, Laurent Poulet, Alain Buguet, Raymond Cespuglio, Frédéric Canin. Metyrapone effects on systemic and cerebral energy metabolism. European journal of pharmacology. vol 682. issue 1-3. 2012-07-17. PMID:22387859. |
in the hippocampus, metyrapone decreased γ-aminobutyric acid (gaba) and glutamate levels but increased glutamine and n-acetyl-aspartate contents (naa). |
2012-07-17 |
2023-08-12 |
rat |
| N A Semenova, S V Sidorin, T A Akhadov, J B Semenova, A V Petraikin, E V Fufaeva, A N Karlos. Effect of cell therapy on metabolite content in brain structures of children with consequences of severe brain injury: 1H magnetic resonance spectroscopy study. Bulletin of experimental biology and medicine. vol 151. issue 4. 2012-07-17. PMID:22448384. |
the effect of intravenous injection of human umbilical cord blood cells on the levels of n-acetylaspartate, creatine and phosphocreatine, choline-containing compounds, glutamine and glutamate, and myoinositol in morphologically intact areas of the cortex, white matter, and hippocampus of children with consequences of traumatic brain injury was studied by single voxel 1h magnetic resonance spectroscopy. |
2012-07-17 |
2023-08-12 |
human |
| Gabriela Vera, Ricardo Tapi. Activation of group III metabotropic glutamate receptors by endogenous glutamate protects against glutamate-mediated excitotoxicity in the hippocampus in vivo. Journal of neuroscience research. vol 90. issue 5. 2012-07-16. PMID:22252898. |
activation of group iii metabotropic glutamate receptors by endogenous glutamate protects against glutamate-mediated excitotoxicity in the hippocampus in vivo. |
2012-07-16 |
2023-08-12 |
rat |
| Gabriela Vera, Ricardo Tapi. Activation of group III metabotropic glutamate receptors by endogenous glutamate protects against glutamate-mediated excitotoxicity in the hippocampus in vivo. Journal of neuroscience research. vol 90. issue 5. 2012-07-16. PMID:22252898. |
perfusion of 4-aminopyridine (4-ap) by microdialysis in the hippocampus produces intense epileptiform behavioral and electrical activity and neurodegeneration, resulting from a stimulated release of glutamate from nerve endings. |
2012-07-16 |
2023-08-12 |
rat |
| Gabriela Vera, Ricardo Tapi. Activation of group III metabotropic glutamate receptors by endogenous glutamate protects against glutamate-mediated excitotoxicity in the hippocampus in vivo. Journal of neuroscience research. vol 90. issue 5. 2012-07-16. PMID:22252898. |
therefore, using microdialysis, eeg recording, and histological evaluation, we studied the effect of increased endogenous extracellular glutamate by blockade of its transport with pyrrolidine dicarboxylic acid (pdc) on the excitotoxic action of 4-ap in the hippocampus of awake rats. |
2012-07-16 |
2023-08-12 |
rat |
| Ana Ledo, R M Barbosa, J Laranjinh. Modulation of cellular respiration by endogenously produced nitric oxide in rat hippocampal slices. Methods in molecular biology (Clifton, N.J.). vol 810. 2012-07-13. PMID:22057561. |
in the hippocampus, neuronal •no production is coupled to the activation of the nmda-type of glutamate receptor. |
2012-07-13 |
2023-08-12 |
rat |
| Marlene J Végh, Monique C de Waard, Ingrid van der Pluijm, Yanto Ridwan, Marion J M Sassen, Pim van Nierop, Roel C van der Schors, Ka Wan Li, Jan H J Hoeijmakers, August B Smit, Ronald E van Kestere. Synaptic proteome changes in a DNA repair deficient ercc1 mouse model of accelerated aging. Journal of proteome research. vol 11. issue 3. 2012-07-09. PMID:22289077. |
however, using isobaric tag for relative and absolute quantification (itraq) of hippocampal synaptic proteins at two different ages, postnatal days 28 and 112, we observed a progressive decrease in synaptic ionotropic glutamate receptor levels and increased levels of g-proteins and of cell adhesion proteins. |
2012-07-09 |
2023-08-12 |
mouse |