| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Irene L Llorente, Diego Perez-Rodriguez, Beatriz Martínez-Villayandre, Severiano Dos-Anjos, Mark G Darlison, Amy V Poole, Arsenio Fernández-Lópe. GABA(A) receptor chloride channels are involved in the neuroprotective role of GABA following oxygen and glucose deprivation in the rat cerebral cortex but not in the hippocampus. Brain research. vol 1533. 2014-04-18. PMID:23969196. |
gaba(a) receptor chloride channels are involved in the neuroprotective role of gaba following oxygen and glucose deprivation in the rat cerebral cortex but not in the hippocampus. |
2014-04-18 |
2023-08-12 |
rat |
| Irene L Llorente, Diego Perez-Rodriguez, Beatriz Martínez-Villayandre, Severiano Dos-Anjos, Mark G Darlison, Amy V Poole, Arsenio Fernández-Lópe. GABA(A) receptor chloride channels are involved in the neuroprotective role of GABA following oxygen and glucose deprivation in the rat cerebral cortex but not in the hippocampus. Brain research. vol 1533. 2014-04-18. PMID:23969196. |
assays on "ex vivo" sections of rat hippocampus and rat cerebral cortex, subjected to oxygen and glucose deprivation (ogd) and a three-hour reperfusion-like (rl) recovery, were performed in the presence of either gaba or the gaba(a) receptor binding site antagonist, bicuculline. |
2014-04-18 |
2023-08-12 |
rat |
| Irene L Llorente, Diego Perez-Rodriguez, Beatriz Martínez-Villayandre, Severiano Dos-Anjos, Mark G Darlison, Amy V Poole, Arsenio Fernández-Lópe. GABA(A) receptor chloride channels are involved in the neuroprotective role of GABA following oxygen and glucose deprivation in the rat cerebral cortex but not in the hippocampus. Brain research. vol 1533. 2014-04-18. PMID:23969196. |
mortality assays revealed that gabaa receptor chloride channels play an important role in the neuroprotective effect of gaba in the cerebral cortex, but have a much smaller effect in the hippocampus. |
2014-04-18 |
2023-08-12 |
rat |
| Paul D Whissell, Dave Eng, Irene Lecker, Loren J Martin, Dian-Shi Wang, Beverley A Orse. Acutely increasing δGABA(A) receptor activity impairs memory and inhibits synaptic plasticity in the hippocampus. Frontiers in neural circuits. vol 7. 2014-04-08. PMID:24062648. |
extrasynaptic γ-aminobutyric acid type a (gaba(a)) receptors that contain the δ subunit (δgaba(a) receptors) are expressed in several brain regions including the dentate gyrus (dg) and ca1 subfields of the hippocampus. |
2014-04-08 |
2023-08-12 |
mouse |
| Paul D Whissell, Dave Eng, Irene Lecker, Loren J Martin, Dian-Shi Wang, Beverley A Orse. Acutely increasing δGABA(A) receptor activity impairs memory and inhibits synaptic plasticity in the hippocampus. Frontiers in neural circuits. vol 7. 2014-04-08. PMID:24062648. |
furthermore, thip inhibited ltp in hippocampal slices from wt but not gabrd(-/-) mice, an effect that was blocked by gaba(a) receptor antagonist bicuculline. |
2014-04-08 |
2023-08-12 |
mouse |
| Y-Y Zhu, L Jing, T-T Duan, Q Yuan, J Cao, Q-X Zhou, L X. Patterned high-frequency stimulation induces a form of long-term depression dependent on GABAA and mACh receptors in the hippocampus. Neuroscience. vol 250. 2014-04-04. PMID:23911810. |
here, we report that a patterned high-frequency stimulation (phs) induces rat hippocampal long-term depression (ltd) in an nmdar-independent manner that requires coactivation of gaba(a)rs and muscarinic acetylcholine receptors (machrs), and endocytosis of ampars. |
2014-04-04 |
2023-08-12 |
rat |
| Kai Spiegelhalder, Wolfram Regen, Chiara Baglioni, Dieter Riemann, John W Winkelma. Neuroimaging studies in insomnia. Current psychiatry reports. vol 15. issue 11. 2014-03-17. PMID:24057158. |
in summary, the current data suggest the following: (1) insomnia is characterized by corticolimbic overactivity during sleep and wakefulness that interferes with sleep initiation and/or maintenance; (2) insomnia patients' daytime performance is associated with a hypoactivation of task-related areas; (3) neurochemically, insomnia patients are probably characterized by reduced cortical gaba levels; (4) insomnia may be associated with abnormal brain morphometry in the frontal cortex, hippocampus and/or anterior cingulate cortex. |
2014-03-17 |
2023-08-12 |
Not clear |
| Carine Smith, Marthinus Janse van Vuure. Central and peripheral effects of Sutherlandia frutescens on the response to acute psychological stress. Experimental biology and medicine (Maywood, N.J.). vol 239. issue 1. 2014-03-17. PMID:24304818. |
after 1 h of exposure to stress, acute restraint resulted in a significant increase in plasma corticosterone levels (56 ± 33 versus 499 ± 50 ng/ml; p < 0.0001) and anterior pituitary adrenocorticotropic hormone (acth) levels (0.066 ± 0.017 versus 0.202 ± 0.033% fluorescent area; p = 0.07), while decreasing hippocampal glucocorticoid receptor (gr) and gamma-aminobutyric acid (gaba)(a)α1 receptor levels (both p < 0.05). |
2014-03-17 |
2023-08-12 |
Not clear |
| Claudio Giachino, Michael Barz, Jan S Tchorz, Mercedes Tome, Martin Gassmann, Josef Bischofberger, Bernhard Bettler, Verdon Taylo. GABA suppresses neurogenesis in the adult hippocampus through GABAB receptors. Development (Cambridge, England). vol 141. issue 1. 2014-03-11. PMID:24284211. |
gaba suppresses neurogenesis in the adult hippocampus through gabab receptors. |
2014-03-11 |
2023-08-12 |
mouse |
| Andrea Pedroni, Do Duc Minh, Antonello Mallamaci, Enrico Cherubin. Electrophysiological characterization of granule cells in the dentate gyrus immediately after birth. Frontiers in cellular neuroscience. vol 8. 2014-03-04. PMID:24592213. |
in addition, most spiking neurons showed spontaneous synchronized network activity, reminiscent of giant depolarizing potentials (gdps) generated in the hippocampus by the synergistic action of glutamate and gaba, both depolarizing and excitatory. |
2014-03-04 |
2023-08-12 |
rat |
| Kiyoshi Egawa, Junko Yamada, Tomonori Furukawa, Yuchio Yanagawa, Atsuo Fukud. Cl⁻ homeodynamics in gap junction-coupled astrocytic networks on activation of GABAergic synapses. The Journal of physiology. vol 591. issue 16. 2014-03-03. PMID:23732644. |
here, we analysed the cl⁻ dynamics of neurons and astrocytes in ca1 hippocampal gabaergic tripartite synapses, using cl⁻ imaging during gaba application, and whole cell recordings from interneuron-astrocyte pairs in the stratum lacunosum-moleculare. |
2014-03-03 |
2023-08-12 |
mouse |
| Masahito Wakita, Naoki Kotani, Kyuya Kogure, Norio Akaik. Inhibition of excitatory synaptic transmission in hippocampal neurons by levetiracetam involves Zn²⁺-dependent GABA type A receptor-mediated presynaptic modulation. The Journal of pharmacology and experimental therapeutics. vol 348. issue 2. 2014-03-03. PMID:24259680. |
inhibition of excitatory synaptic transmission in hippocampal neurons by levetiracetam involves zn²⁺-dependent gaba type a receptor-mediated presynaptic modulation. |
2014-03-03 |
2023-08-12 |
Not clear |
| Roman Tyzio, Romain Nardou, Diana C Ferrari, Timur Tsintsadze, Amene Shahrokhi, Sanaz Eftekhari, Ilgam Khalilov, Vera Tsintsadze, Corinne Brouchoud, Genevieve Chazal, Eric Lemonnier, Natalia Lozovaya, Nail Burnashev, Yehezkel Ben-Ar. Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring. Science (New York, N.Y.). vol 343. issue 6171. 2014-02-25. PMID:24503856. |
during delivery and subsequently, hippocampal neurons in these models have elevated intracellular chloride levels, increased excitatory gaba, enhanced glutamatergic activity, and elevated gamma oscillations. |
2014-02-25 |
2023-08-12 |
Not clear |
| Noélle D Germain, Erin C Banda, Sandy Becker, Janice R Naegele, Laura B Grabe. Derivation and isolation of NKX2.1-positive basal forebrain progenitors from human embryonic stem cells. Stem cells and development. vol 22. issue 10. 2014-02-20. PMID:23351095. |
gamma aminobutyric acid (gaba)-expressing interneurons are the major inhibitory cells of the cerebral cortex and hippocampus. |
2014-02-20 |
2023-08-12 |
human |
| L Ferraro, A Loche, S Beggiato, M C Tomasini, T Antonelli, G Colombo, C Lobina, M A M Carai, A Porcu, M P Castelli, F Clerici, A C Borelli, R Cacciaglia, S Tanganell. The new compound GET73, N-[(4-trifluoromethyl)benzyl]4-methoxybutyramide, Regulates hippocampal Aminoacidergic transmission possibly via an allosteric modulation of mGlu5 receptor. Behavioural evidence of its "anti-alcohol" and anxiolytic properties. Current medicinal chemistry. vol 20. issue 27. 2014-02-20. PMID:23862615. |
particular emphasis is given to findings obtained in vivo and in vitro suggesting that an allosteric modulation of metabotropic glutamate receptor 5 (mglu5 receptor) by get73 may represent the mechanism underlying the effects of the compound produced on rat hippocampal glutamate and gaba transmission. |
2014-02-20 |
2023-08-12 |
rat |
| Shahid Ali Shah, Ikram Ullah, Hae Young Lee, Myeong Ok Ki. Anthocyanins protect against ethanol-induced neuronal apoptosis via GABAB1 receptors intracellular signaling in prenatal rat hippocampal neurons. Molecular neurobiology. vol 48. issue 1. 2014-02-12. PMID:23645118. |
here, we investigated the possible involvement of gamma-aminobutyric acid b1 receptor (gabab1r) in mediating the protective effects of black soybean anthocyanins against ethanol-induced apoptosis in prenatal hippocampal neurons because gabars are known to play an important role in the development of central nervous system. |
2014-02-12 |
2023-08-12 |
rat |
| Yinghua Yu, Yizhen Wu, Craig Patch, Zhixiang Wu, Alexander Szabo, Duo Li, Xu-Feng Huan. DHA prevents altered 5-HT1A, 5-HT2A, CB1 and GABAA receptor binding densities in the brain of male rats fed a high-saturated-fat diet. The Journal of nutritional biochemistry. vol 24. issue 7. 2014-01-29. PMID:23337348. |
in the hippocampus, the 5-ht(1a), cb1 and gaba(a) receptor binding densities significantly increased in response to an hf diet, while in the hypothalamus, 5-ht(1a) and cb1 binding densities significantly increased in hf-fed rats. |
2014-01-29 |
2023-08-12 |
rat |
| E Venzala, A L García-García, N Elizalde, R M Torder. Social vs. environmental stress models of depression from a behavioural and neurochemical approach. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 7. 2014-01-23. PMID:22743048. |
subsequently, we examined glutamate, gaba, 5-ht and dopamine levels in the prefrontal cortex, hippocampus and brainstem. |
2014-01-23 |
2023-08-12 |
mouse |
| Jiajia Yang, Zhaowei Liu, Yongling Xie, Zhuo Yang, Tao Zhan. Peroxynitrite alters GABAergic synaptic transmission in immature rat hippocampal slices. Neuroscience research. vol 75. issue 3. 2014-01-20. PMID:23357207. |
this study provides electrophysiological evidences from developing hippocampal slices to support that sin-1 enhances action potential-dependent gaba release. |
2014-01-20 |
2023-08-12 |
rat |
| Qian Bu, Lei Lv, Guangyan Yan, Pengchi Deng, Yanli Wang, Jiaqing Zhou, Yanzhu Yang, Yan Li, Xiaobo Ce. NMR-based metabonomic in hippocampus, nucleus accumbens and prefrontal cortex of methamphetamine-sensitized rats. Neurotoxicology. vol 36. 2014-01-13. PMID:23462569. |
the neurotransmitters glutamate, glutamine and gaba significantly decreased in hippocampus, nac and pfc. |
2014-01-13 |
2023-08-12 |
rat |