| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Madeleine V King, Nisha Kurian, Si Qin, Nektaria Papadopoulou, Ben H C Westerink, Thomas I Cremers, Mark P Epping-Jordan, Emmanuel Le Poul, David E Ray, Kevin C F Fone, David A Kendall, Charles A Marsden, Tyson V Shar. Lentiviral delivery of a vesicular glutamate transporter 1 (VGLUT1)-targeting short hairpin RNA vector into the mouse hippocampus impairs cognition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 2. 2014-08-21. PMID:24037344. |
the vglut1-targeting vector attenuated tonic glutamate release in the dorsal hippocampus without affecting gaba, and selectively impaired novel object discrimination (nod) and retention (but not acquisition) in the morris water maze, without influencing contextual fear-motivated learning or causing any adverse locomotor or central immune effects. |
2014-08-21 |
2023-08-12 |
mouse |
| Archana Proddutur, Jiandong Yu, Fatima S Elgammal, Vijayalakshmi Santhakuma. Seizure-induced alterations in fast-spiking basket cell GABA currents modulate frequency and coherence of gamma oscillation in network simulations. Chaos (Woodbury, N.Y.). vol 23. issue 4. 2014-08-18. PMID:24387588. |
90, 1195 (2010)], our demonstration that network oscillations are modulated by extrasynaptic inhibition in fs-bcs suggests that neuroactive compounds that act on extrasynaptic gaba receptors could impact memory formation by modulating hippocampal gamma oscillations. |
2014-08-18 |
2023-08-12 |
Not clear |
| Naruyoshi Fujiwara, Jun Shimizu, Kenji Takai, Nagisa Arimitsu, Asako Saito, Takao Kono, Tasuku Umehara, Yuji Ueda, Sueshige Wakisaka, Tomoko Suzuki, Noboru Suzuk. Restoration of spatial memory dysfunction of human APP transgenic mice by transplantation of neuronal precursors derived from human iPS cells. Neuroscience letters. vol 557 Pt B. 2014-08-18. PMID:24466594. |
we observed choline acetyltransferase (chat) positive cholinergic human neurons and vesicle gaba transporter (vgat) positive gabaergic human neurons in pdapp mouse hippocampus 45 days after the transplantation. |
2014-08-18 |
2023-08-12 |
mouse |
| Marie Soukupová, Anna Binaschi, Chiara Falcicchia, Silvia Zucchini, Paolo Roncon, Eleonora Palma, Eros Magri, Enrico Grandi, Michele Simonat. Impairment of GABA release in the hippocampus at the time of the first spontaneous seizure in the pilocarpine model of temporal lobe epilepsy. Experimental neurology. vol 257. 2014-08-13. PMID:24768627. |
impairment of gaba release in the hippocampus at the time of the first spontaneous seizure in the pilocarpine model of temporal lobe epilepsy. |
2014-08-13 |
2023-08-13 |
rat |
| Marie Soukupová, Anna Binaschi, Chiara Falcicchia, Silvia Zucchini, Paolo Roncon, Eleonora Palma, Eros Magri, Enrico Grandi, Michele Simonat. Impairment of GABA release in the hippocampus at the time of the first spontaneous seizure in the pilocarpine model of temporal lobe epilepsy. Experimental neurology. vol 257. 2014-08-13. PMID:24768627. |
in this work, we analyzed gaba extracellular concentrations (using in vivo microdialysis under basal and high k(+)-evoked conditions) and loss of two gaba interneuron populations (parvalbumin and somatostatin neurons) in the ventral hippocampus at different time-points after pilocarpine-induced status epilepticus in the rat, i.e. |
2014-08-13 |
2023-08-13 |
rat |
| Giorgia Quadrato, Mohamed Y Elnaggar, Ceren Duman, Andrea Sabino, Kirsi Forsberg, Simone Di Giovann. Modulation of GABAA receptor signaling increases neurogenesis and suppresses anxiety through NFATc4. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 25. 2014-08-12. PMID:24948817. |
here, we identify nfatc4 as a key activity-dependent transcriptional regulator of gaba signaling in hippocampal progenitor cells via an unbiased high-throughput genome-wide study. |
2014-08-12 |
2023-08-13 |
mouse |
| Toshika Ohkawa, Shin'Ichiro Satake, Norihiko Yokoi, Yu Miyazaki, Tomohiko Ohshita, Gen Sobue, Hiroshi Takashima, Osamu Watanabe, Yuko Fukata, Masaki Fukat. Identification and characterization of GABA(A) receptor autoantibodies in autoimmune encephalitis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 24. 2014-08-04. PMID:24920620. |
the β3-subunit-containing gaba(a) receptor was a major target of the patients' serum antibodies in rat hippocampal neurons because the serum reactivity to the neuronal surface was greatly decreased by 80% when the β3 subunit was knocked down. |
2014-08-04 |
2023-08-13 |
human |
| Toshika Ohkawa, Shin'Ichiro Satake, Norihiko Yokoi, Yu Miyazaki, Tomohiko Ohshita, Gen Sobue, Hiroshi Takashima, Osamu Watanabe, Yuko Fukata, Masaki Fukat. Identification and characterization of GABA(A) receptor autoantibodies in autoimmune encephalitis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 24. 2014-08-04. PMID:24920620. |
application of the patients' serum at the time of symptom presentation of encephalitis to rat hippocampal neuron cultures specifically decreased both synaptic and surface gaba(a) receptors. |
2014-08-04 |
2023-08-13 |
human |
| Natalia Pozdnyakova, Marina Dudarenko, Ludmila Yatsenko, Nina Himmelreich, Olga Krupko, Tatiana Borisov. Perinatal hypoxia: different effects of the inhibitors of GABA transporters GAT1 and GAT3 on the initial velocity of [3H]GABA uptake by cortical, hippocampal, and thalamic nerve terminals. Croatian medical journal. vol 55. issue 3. 2014-08-01. PMID:24891283. |
perinatal hypoxia: different effects of the inhibitors of gaba transporters gat1 and gat3 on the initial velocity of [3h]gaba uptake by cortical, hippocampal, and thalamic nerve terminals. |
2014-08-01 |
2023-08-13 |
rat |
| Natalia Pozdnyakova, Marina Dudarenko, Ludmila Yatsenko, Nina Himmelreich, Olga Krupko, Tatiana Borisov. Perinatal hypoxia: different effects of the inhibitors of GABA transporters GAT1 and GAT3 on the initial velocity of [3H]GABA uptake by cortical, hippocampal, and thalamic nerve terminals. Croatian medical journal. vol 55. issue 3. 2014-08-01. PMID:24891283. |
to analyze the effects of highly selective blocker gat1, no-711, and substrate inhibitor gat3, β-alanine, on the initial velocity of [(3)h]gaba uptake by cortical, hippocampal, and thalamic nerve terminals (synaptosomes) after perinatal hypoxia. |
2014-08-01 |
2023-08-13 |
rat |
| Natalia Pozdnyakova, Marina Dudarenko, Ludmila Yatsenko, Nina Himmelreich, Olga Krupko, Tatiana Borisov. Perinatal hypoxia: different effects of the inhibitors of GABA transporters GAT1 and GAT3 on the initial velocity of [3H]GABA uptake by cortical, hippocampal, and thalamic nerve terminals. Croatian medical journal. vol 55. issue 3. 2014-08-01. PMID:24891283. |
in hippocampal synaptosomes, no-711 inhibited 84.3% of the initial velocity of [(3)h]gaba uptake in normal conditions and 80.1% after hypoxia, whereas the effect of β-alanine was increased after hypoxia from 14.4% to 22.1%. |
2014-08-01 |
2023-08-13 |
rat |
| Natalia Pozdnyakova, Marina Dudarenko, Ludmila Yatsenko, Nina Himmelreich, Olga Krupko, Tatiana Borisov. Perinatal hypoxia: different effects of the inhibitors of GABA transporters GAT1 and GAT3 on the initial velocity of [3H]GABA uptake by cortical, hippocampal, and thalamic nerve terminals. Croatian medical journal. vol 55. issue 3. 2014-08-01. PMID:24891283. |
the effectiveness of β-alanine to influence gaba uptake was increased in hippocampal and thalamic nerve terminals as a result of perinatal hypoxia and the effectiveness of no-711 in thalamic nerve terminals was decreased. |
2014-08-01 |
2023-08-13 |
rat |
| Toni-Lee Sterley, Fleur M Howells, Vivienne A Russel. Evidence for reduced tonic levels of GABA in the hippocampus of an animal model of ADHD, the spontaneously hypertensive rat. Brain research. vol 1541. 2014-07-28. PMID:24161405. |
evidence for reduced tonic levels of gaba in the hippocampus of an animal model of adhd, the spontaneously hypertensive rat. |
2014-07-28 |
2023-08-12 |
rat |
| Toni-Lee Sterley, Fleur M Howells, Vivienne A Russel. Evidence for reduced tonic levels of GABA in the hippocampus of an animal model of ADHD, the spontaneously hypertensive rat. Brain research. vol 1541. 2014-07-28. PMID:24161405. |
in the present study, we investigated how the level of extracellular (tonic) gaba affects release of [(3)h]ne in hippocampal slices of male and female shr, wky and sd rats, in response to 3 glutamate stimulations (s1, s2, and s3). |
2014-07-28 |
2023-08-12 |
rat |
| Toni-Lee Sterley, Fleur M Howells, Vivienne A Russel. Evidence for reduced tonic levels of GABA in the hippocampus of an animal model of ADHD, the spontaneously hypertensive rat. Brain research. vol 1541. 2014-07-28. PMID:24161405. |
the hippocampal slices were prelabelled with [(3)h]ne and superfused with buffer containing 0μm, 1μm, 10μm, or 100μm gaba. |
2014-07-28 |
2023-08-12 |
rat |
| Toni-Lee Sterley, Fleur M Howells, Vivienne A Russel. Evidence for reduced tonic levels of GABA in the hippocampus of an animal model of ADHD, the spontaneously hypertensive rat. Brain research. vol 1541. 2014-07-28. PMID:24161405. |
when gaba was omitted from the superfusion buffer used to perfuse shr hippocampal slices, but present at 100µm in the buffer used to perfuse wky and sd hippocampal slices, glutamate-stimulated release of [(3)h]ne was similar in all three strains. |
2014-07-28 |
2023-08-12 |
rat |
| Toni-Lee Sterley, Fleur M Howells, Vivienne A Russel. Evidence for reduced tonic levels of GABA in the hippocampus of an animal model of ADHD, the spontaneously hypertensive rat. Brain research. vol 1541. 2014-07-28. PMID:24161405. |
these findings suggest that extracellular concentrations of gaba may be reduced in shr hippocampus, in vivo, compared to wky and sd. |
2014-07-28 |
2023-08-12 |
rat |
| Ashok Jangra, Ashok Kumar Datusalia, Shriya Khandwe, Shyam Sunder Sharm. Amelioration of diabetes-induced neurobehavioral and neurochemical changes by melatonin and nicotinamide: implication of oxidative stress-PARP pathway. Pharmacology, biochemistry, and behavior. vol 114-115. 2014-07-22. PMID:24201044. |
glutamate and gaba levels were also altered in hippocampus of the diabetic animals. |
2014-07-22 |
2023-08-12 |
rat |
| Ahmed I Gilani, Muhammad O Chohan, Melis Inan, Scott A Schobel, Nashid H Chaudhury, Samuel Paskewitz, Nao Chuhma, Sara Glickstein, Robert J Merker, Qing Xu, Scott A Small, Stewart A Anderson, Margaret Elizabeth Ross, Holly Moor. Interneuron precursor transplants in adult hippocampus reverse psychosis-relevant features in a mouse model of hippocampal disinhibition. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 20. 2014-07-15. PMID:24794528. |
these findings establish functional links between hippocampal gaba interneuron deficits and psychosis-relevant dopaminergic and cognitive phenotypes, and support a rationale for targeting limbic cortical interneuron function in the prevention and treatment of schizophrenia. |
2014-07-15 |
2023-08-13 |
mouse |
| Damian P Bright, Trevor G Smar. Protein kinase C regulates tonic GABA(A) receptor-mediated inhibition in the hippocampus and thalamus. The European journal of neuroscience. vol 38. issue 10. 2014-07-08. PMID:24102973. |
protein kinase c regulates tonic gaba(a) receptor-mediated inhibition in the hippocampus and thalamus. |
2014-07-08 |
2023-08-12 |
human |