| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Damian P Bright, Trevor G Smar. Protein kinase C regulates tonic GABA(A) receptor-mediated inhibition in the hippocampus and thalamus. The European journal of neuroscience. vol 38. issue 10. 2014-07-08. PMID:24102973. |
recordings from dentate gyrus granule cells in the hippocampus and dorsal lateral geniculate relay neurons in the thalamus demonstrated that pkc activation caused downregulation of tonic gaba(a) r-mediated inhibition. |
2014-07-08 |
2023-08-12 |
human |
| Damian P Bright, Trevor G Smar. Protein kinase C regulates tonic GABA(A) receptor-mediated inhibition in the hippocampus and thalamus. The European journal of neuroscience. vol 38. issue 10. 2014-07-08. PMID:24102973. |
these findings were corroborated by experiments on human embryonic kidney 293 cells expressing recombinant α4β2δ gaba(a) rs, which represent a key extrasynaptic gaba(a) r isoform in the hippocampus and thalamus. |
2014-07-08 |
2023-08-12 |
human |
| Marieangela C Wilson, Michaela Kraus, Hassan Marzban, Justyna R Sarna, Yisong Wang, Richard Hawkes, Andrew P Halestrap, Philip W Beesle. The neuroplastin adhesion molecules are accessory proteins that chaperone the monocarboxylate transporter MCT2 to the neuronal cell surface. PloS one. vol 8. issue 11. 2014-07-07. PMID:24260123. |
np65 regulates the surface expression of glur1 receptor subunits and the localisation of gaba(a) receptor subtypes in hippocampal neurones. |
2014-07-07 |
2023-08-12 |
Not clear |
| Marta Pallotto, Francine Depre. Regulation of adult neurogenesis by GABAergic transmission: signaling beyond GABAA-receptors. Frontiers in cellular neuroscience. vol 8. 2014-07-07. PMID:24999317. |
in this review, we systematically compare the role of gabaergic transmission in the regulation of adult neurogenesis between the ob and the hippocampus, focusing on the role of gaba in modulating plasticity and critical periods of adult-born neuron development. |
2014-07-07 |
2023-08-13 |
Not clear |
| Andrew P Mayer, Ivan Osorio, Craig E Lunt. Microperfusion of 3-MPA into the brain augments GABA. Epilepsy & behavior : E&B. vol 29. issue 3. 2014-07-03. PMID:24094842. |
in vivo effects of microperfusion of a gaba synthesis inhibitor (3-mpa) into the striatum and hippocampus on amino acid concentrations and electrical neuronal activity were investigated. |
2014-07-03 |
2023-08-12 |
rat |
| Andrew P Mayer, Ivan Osorio, Craig E Lunt. Microperfusion of 3-MPA into the brain augments GABA. Epilepsy & behavior : E&B. vol 29. issue 3. 2014-07-03. PMID:24094842. |
paradoxical elevations in gaba in the striatum (5-fold in anesthetized and 50-fold in awake rats) and hippocampus (2-fold in anesthetized and 15-fold in awake rats) were documented under steady-state concentrations of 3-mpa along with expected increases in glutamate (a 15-fold increase and a 250-fold increase in the striatum of anesthetized and awake rats, respectively; a 7-fold increase and a 25-fold increase in the hippocampus of anesthetized and awake rats, respectively). |
2014-07-03 |
2023-08-12 |
rat |
| Sheela Toprani, Dominique M Duran. Long-lasting hyperpolarization underlies seizure reduction by low frequency deep brain electrical stimulation. The Journal of physiology. vol 591. issue 22. 2014-06-24. PMID:23981713. |
these data show that lfs of the vhc is an effective protocol for bilateral hippocampal seizure reduction and that its efficacy relies on the induction of long-lasting hyperpolarization mediated through gaba(b) ipsps and sahp. |
2014-06-24 |
2023-08-12 |
human |
| Yao Ding, Shan Wang, Yan Jiang, Yi Yang, Manman Zhang, Yi Guo, Shuang Wang, Mei-ping Din. Fructose-1,6-diphosphate protects against epileptogenesis by modifying cation-chloride co-transporters in a model of amygdaloid-kindling temporal epilepticus. Brain research. vol 1539. 2014-06-20. PMID:24095797. |
in hippocampal neurons, cation-chloride co-transporters (cccs) are suggested to play interesting roles in epilepsy by modulating γ-aminobutyric acid (gaba)ergic activity through controlling gabaa receptor-mediated reversal potential. |
2014-06-20 |
2023-08-12 |
human |
| Libai Yang, Xiaodong Cai, Jueqian Zhou, Shuda Chen, Yishu Chen, Ziyi Chen, Qian Wang, Ziyan Fang, Liemin Zho. STE20/SPS1-related proline/alanine-rich kinase is involved in plasticity of GABA signaling function in a mouse model of acquired epilepsy. PloS one. vol 8. issue 9. 2014-06-16. PMID:24058604. |
our data suggests that spak is involved in the plasticity of gaba signaling function in acquired epilepsy via adjustment of [cl(-)]i in hippocampal neurons. |
2014-06-16 |
2023-08-12 |
mouse |
| Elham H A Ali, Amany H Mahmoud Elgol. Combined prenatal and postnatal butyl paraben exposure produces autism-like symptoms in offspring: comparison with valproic acid autistic model. Pharmacology, biochemistry, and behavior. vol 111. 2014-06-13. PMID:24036472. |
the alterations were recorded notably in hippocampus and pons ne, midbrain da, hippocampus and midbrain 5-ht, and frontal cortex gaba and asparagine. |
2014-06-13 |
2023-08-12 |
rat |
| Paula M Canas, Ana Patrícia Simões, Ricardo J Rodrigues, Rodrigo A Cunh. Predominant loss of glutamatergic terminal markers in a β-amyloid peptide model of Alzheimer's disease. Neuropharmacology. vol 76 Pt A. 2014-06-05. PMID:24029236. |
western blot analysis revealed a decrease of the density of vesicular glutamate transporters type 1 (vglut1, a marker of glutamatergic terminals; -20.1 ± 3.6%) and of vesicular acetylcholine transporters (vacht, a marker of cholinergic terminals; -27.2 ± 0.9%) but not of vesicular gaba transporters (vgat, a marker of gabaergic terminals) in the hippocampus of aβ-injected mice. |
2014-06-05 |
2023-08-12 |
mouse |
| Elisa Merega, Silvia Di Prisco, Massimiliano Lanfranco, Paolo Severi, Anna Pittalug. Complement selectively elicits glutamate release from nerve endings in different regions of mammal central nervous system. Journal of neurochemistry. vol 129. issue 3. 2014-06-04. PMID:24387009. |
it also evoked [(3) h]d-asp release from mouse hippocampal, cerebellar, and spinal cord synaptosomes, as well as from rat and human cortical nerve endings, but left unaltered the release of gaba, [(3) h]noradrenaline or [(3) h]acetylcholine. |
2014-06-04 |
2023-08-12 |
mouse |
| T M Eriksson, A Alvarsson, T L Stan, X Zhang, K N Hascup, E R Hascup, J Kehr, G A Gerhardt, J Warner-Schmidt, M Arango-Lievano, M G Kaplitt, S O Ogren, P Greengard, P Svenningsso. Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11. Molecular psychiatry. vol 18. issue 10. 2014-05-29. PMID:23032875. |
magnetic resonance spectroscopy demonstrated global hippocampal reductions of inhibitory gaba, which may contribute to the memory enhancement and potentiation of pre- and post-synaptic measures of glutamate transmission by a 5-ht(1b)r agonist in p11ko mice. |
2014-05-29 |
2023-08-12 |
mouse |
| Cristiano Bombardi, Giuseppe Di Giovann. Functional anatomy of 5-HT2A receptors in the amygdala and hippocampal complex: relevance to memory functions. Experimental brain research. vol 230. issue 4. 2014-05-27. PMID:23591691. |
5-ht2a receptors on gabaergic interneurons stimulate gaba release, and thereby have an important role in regulating network activity and neural oscillations in the amygdala and hippocampal region. |
2014-05-27 |
2023-08-12 |
Not clear |
| Abdeslem El Idrissi, Chang Hui Shen, William J L'amoreau. Neuroprotective role of taurine during aging. Amino acids. vol 45. issue 4. 2014-05-26. PMID:23963537. |
these changes included (1) increased levels of the neurotransmitters gaba and glutamate, (2) increased expression of both isoforms of gad (65 and 67) and the neuropeptide somatostatin, (3) decreased hippocampal expression of the β3 subunits of the gabaa receptor, (4) increased expression in the number of somatostatin-positive neurons, (5) increased amplitude and duration of population spikes recorded from ca1 in response to schaefer collateral stimulation and (6) enhanced paired pulse facilitation in the hippocampus. |
2014-05-26 |
2023-08-12 |
mouse |
| Carla G Silva, Christine Métin, Walid Fazeli, Nuno J Machado, Sanja Darmopil, Pierre-Serge Launay, Antoine Ghestem, Marie-Pascale Nesa, Emilie Bassot, Eszter Szabó, Younis Baqi, Christa E Müller, Angelo R Tomé, Anton Ivanov, Dirk Isbrandt, Yuri Zilberter, Rodrigo A Cunha, Monique Esclapez, Christophe Bernar. Adenosine receptor antagonists including caffeine alter fetal brain development in mice. Science translational medicine. vol 5. issue 197. 2014-05-19. PMID:23926202. |
we observed delayed migration and insertion of γ-aminobutyric acid (gaba) neurons into the hippocampal circuitry during the first postnatal week in offspring of dams treated with the a2ar antagonist or caffeine. |
2014-05-19 |
2023-08-12 |
mouse |
| Carla G Silva, Christine Métin, Walid Fazeli, Nuno J Machado, Sanja Darmopil, Pierre-Serge Launay, Antoine Ghestem, Marie-Pascale Nesa, Emilie Bassot, Eszter Szabó, Younis Baqi, Christa E Müller, Angelo R Tomé, Anton Ivanov, Dirk Isbrandt, Yuri Zilberter, Rodrigo A Cunha, Monique Esclapez, Christophe Bernar. Adenosine receptor antagonists including caffeine alter fetal brain development in mice. Science translational medicine. vol 5. issue 197. 2014-05-19. PMID:23926202. |
adult offspring of mouse dams exposed to a2ar antagonists during pregnancy and lactation displayed loss of hippocampal gaba neurons and some cognitive deficits. |
2014-05-19 |
2023-08-12 |
mouse |
| Giada Cellot, Enrico Cherubin. Functional role of ambient GABA in refining neuronal circuits early in postnatal development. Frontiers in neural circuits. vol 7. 2014-05-19. PMID:23964205. |
in particular, we focus on the hippocampus, where, prior to the formation of conventional synapses, gaba released from growth cones and astrocytes in a calcium- and snare (soluble n-ethylmaleimide-sensitive-factor attachment protein receptor)-independent way, diffuses away to activate in a paracrine fashion extrasynaptic receptors localized on distal neurons. |
2014-05-19 |
2023-08-12 |
Not clear |
| Z-X Li, H-M Yu, K-W Jian. Tonic GABA inhibition in hippocampal dentate granule cells: its regulation and function in temporal lobe epilepsies. Acta physiologica (Oxford, England). vol 209. issue 3. 2014-05-09. PMID:23865761. |
tonic gaba inhibition in hippocampal dentate granule cells: its regulation and function in temporal lobe epilepsies. |
2014-05-09 |
2023-08-12 |
human |
| Rokuya Nochi, Jun Kaneko, Natsumi Okada, Yasushi Terazono, Ayumu Matani, Tatsuhiro Hisatsun. Diazepam treatment blocks the elevation of hippocampal activity and the accelerated proliferation of hippocampal neural stem cells after focal cerebral ischemia in mice. Journal of neuroscience research. vol 91. issue 11. 2014-05-02. PMID:23963779. |
however, diazepam might have effects other than the suppression of hippocampal activity, so we performed additional experiment and found that diazepam did not affect the number of bromodeoxyuridine-positive cells under the normal condition, whereas the gaba agonist pentobarbital stimulated nsc/neural progenitor cell proliferation and differentiation. |
2014-05-02 |
2023-08-12 |
mouse |