| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gisele Pereira Dias, Mário Cesar do Nascimento Bevilaqua, Anna Claudia Domingos Silveira da Luz, Renata Lopes Fleming, Lítia Alves de Carvalho, Graham Cocks, Danielle Beckman, Lucas Costa Hosken, William de Sant'Anna Machado, Ana Carolina Corrêa-e-Castro, Felippe Mousovich-Neto, Vítor de Castro Gomes, Gilmara de Nazareth Tavares Bastos, Regina Célia Cussa Kubrusly, Vânia Maria Corrêa da Costa, Deepak Srivastava, Jesus Landeira-Fernandez, Antonio Egidio Nardi, Sandrine Thuret, Patricia Franca Gardin. Hippocampal biomarkers of fear memory in an animal model of generalized anxiety disorder. Behavioural brain research. vol 263. 2014-12-03. PMID:24462725. |
hippocampal gaba release was assessed by neurochemical assay. |
2014-12-03 |
2023-08-12 |
rat |
| Gisele Pereira Dias, Mário Cesar do Nascimento Bevilaqua, Anna Claudia Domingos Silveira da Luz, Renata Lopes Fleming, Lítia Alves de Carvalho, Graham Cocks, Danielle Beckman, Lucas Costa Hosken, William de Sant'Anna Machado, Ana Carolina Corrêa-e-Castro, Felippe Mousovich-Neto, Vítor de Castro Gomes, Gilmara de Nazareth Tavares Bastos, Regina Célia Cussa Kubrusly, Vânia Maria Corrêa da Costa, Deepak Srivastava, Jesus Landeira-Fernandez, Antonio Egidio Nardi, Sandrine Thuret, Patricia Franca Gardin. Hippocampal biomarkers of fear memory in an animal model of generalized anxiety disorder. Behavioural brain research. vol 263. 2014-12-03. PMID:24462725. |
increased expression of probdnf and dendritic spines was observed; lower ratio of gaba release in the hippocampus was also verified. |
2014-12-03 |
2023-08-12 |
rat |
| Jie Gao, He Wang, Yuan Liu, Ying-Yu Li, Can Chen, Liang-Ming Liu, Ya-Min Wu, Sen Li, Ce Yan. Glutamate and GABA imbalance promotes neuronal apoptosis in hippocampus after stress. Medical science monitor : international medical journal of experimental and clinical research. vol 20. 2014-11-18. PMID:24675061. |
glutamate and gaba imbalance promotes neuronal apoptosis in hippocampus after stress. |
2014-11-18 |
2023-08-12 |
Not clear |
| Carolyn R House. Do structural changes in GABA neurons give rise to the epileptic state? Advances in experimental medicine and biology. vol 813. 2014-11-18. PMID:25012374. |
because of the diversity of gaba neurons in the hippocampus and cerebral cortex, resulting functional deficits are unlikely to be compensated fully by remaining gaba neurons of other subtypes. |
2014-11-18 |
2023-08-13 |
mouse |
| Miranda Mele, Luís Ribeiro, Ana R Inácio, Tadeusz Wieloch, Carlos B Duart. GABA(A) receptor dephosphorylation followed by internalization is coupled to neuronal death in in vitro ischemia. Neurobiology of disease. vol 65. 2014-11-13. PMID:24513087. |
here we report a downregulation of gaba(a) receptor (gaba(a)r) expression, affecting both mrna and protein levels of gaba(a)r subunits, in hippocampal neurons subjected to oxygen-glucose deprivation (ogd), an in vitro model of ischemia. |
2014-11-13 |
2023-08-12 |
Not clear |
| Miranda Mele, Luís Ribeiro, Ana R Inácio, Tadeusz Wieloch, Carlos B Duart. GABA(A) receptor dephosphorylation followed by internalization is coupled to neuronal death in in vitro ischemia. Neurobiology of disease. vol 65. 2014-11-13. PMID:24513087. |
expression of phospho-mimetic mutant gaba(a)r β3 subunits prevented receptor internalization and protected hippocampal neurons from ischemic cell death. |
2014-11-13 |
2023-08-12 |
Not clear |
| Antonia Grauert, Dominique Engel, Arnaud J Rui. Endogenous zinc depresses GABAergic transmission via T-type Ca(2+) channels and broadens the time window for integration of glutamatergic inputs in dentate granule cells. The Journal of physiology. vol 592. issue 1. 2014-11-11. PMID:24081159. |
thus, zinc-mediated modulation of dentate interneurone excitability and gaba release regulates information flow to local targets and hippocampal networks. |
2014-11-11 |
2023-08-12 |
Not clear |
| M R Winawer, T L Klassen, S Teed, M Shipman, E H Leung, A A Palme. A locus on mouse Ch10 influences susceptibility to limbic seizure severity: fine mapping and in silico candidate gene analysis. Genes, brain, and behavior. vol 13. issue 3. 2014-11-07. PMID:24373497. |
these include stat2, which plays a role in hippocampal gaba receptor expression after status epilepticus, and novel candidates pan2, cdk2, gls2 and cs, which are involved in neural cell differentiation, cellular remodeling and embryonic development. |
2014-11-07 |
2023-08-12 |
mouse |
| Hualong Wang, Kaoqi Lian, Bing Han, Yanyong Wang, Sheng-Han Kuo, Yuan Geng, Jing Qiang, Meiyu Sun, Mingwei Wan. Age-related alterations in the metabolic profile in the hippocampus of the senescence-accelerated mouse prone 8: a spontaneous Alzheimer's disease mouse model. Journal of Alzheimer's disease : JAD. vol 39. issue 4. 2014-10-30. PMID:24284365. |
alterations in 17 metabolites were detected in mature and aged mice compared to young mice (13 decreased and 4 increased metabolites), including metabolites related to dysfunctional lipid metabolism (significantly increased cholesterol, oleic acid, and phosphoglyceride levels), decreased amino acid (alanine, serine, glycine, aspartic acid, glutamate, and gamma-aminobutyric acid), and energy-related metabolite levels (malic acid, butanedioic acid, fumaric acid, and citric acid), and other altered metabolites (increased n-acetyl-aspartic acid and decreased pyroglutamic acid, urea, and lactic acid) in the hippocampus. |
2014-10-30 |
2023-08-12 |
mouse |
| Salim Sharopov, Rongqing Chen, Haiyan Sun, Sergei N Kolbaev, Sergei Kirischuk, Heiko J Luhmann, Werner Kil. Inhibition of different GABA transporter systems is required to attenuate epileptiform activity in the CA3 region of the immature rat hippocampus. Epilepsy research. vol 108. issue 2. 2014-10-30. PMID:24359690. |
inhibition of different gaba transporter systems is required to attenuate epileptiform activity in the ca3 region of the immature rat hippocampus. |
2014-10-30 |
2023-08-12 |
rat |
| Eman S H Abd Allah, Asmaa M S Gomaa, Manal M Saye. The effect of omega-3 on cognition in hypothyroid adult male rats. Acta physiologica Hungarica. vol 101. issue 3. 2014-10-24. PMID:25183510. |
serum total antioxidant capacity (tac) and hippocampal serotonin and γ-aminobutyric acid (gaba) levels were decreased in the hypothyroid group as compared to the control group. |
2014-10-24 |
2023-08-13 |
rat |
| Alessia Salamone, Elisa Mura, Stefania Zappettini, Massimo Grilli, Guendalina Olivero, Stefania Preda, Stefano Govoni, Mario March. Inhibitory effects of beta-amyloid on the nicotinic receptors which stimulate glutamate release in rat hippocampus: the glial contribution. European journal of pharmacology. vol 723. 2014-10-07. PMID:24275353. |
we investigated on the neuronal nicotinic acetylcholine receptor subtypes involved in the cholinergic control of in vivo hippocampal glutamate (glu), aspartate (asp) and inhibitory γ-aminobutyric acid (gaba) overflow. |
2014-10-07 |
2023-08-12 |
rat |
| Sampsa T Sipilä, Albert Spoljaric, Mari A Virtanen, Inkeri Hiironniemi, Kai Kail. Glycine transporter-1 controls nonsynaptic inhibitory actions of glycine receptors in the neonatal rat hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 30. 2014-09-22. PMID:25057202. |
the present data show that, akin to gaba uptake, glyt1 exerts a powerful modulatory action on network events in the newborn hippocampus. |
2014-09-22 |
2023-08-13 |
rat |
| Tatjana Begenisic, Laura Baroncelli, Gabriele Sansevero, Marco Milanese, Tiziana Bonifacino, Giambattista Bonanno, Giovanni Cioni, Lamberto Maffei, Alessandro Sal. Fluoxetine in adulthood normalizes GABA release and rescues hippocampal synaptic plasticity and spatial memory in a mouse model of Down syndrome. Neurobiology of disease. vol 63. 2014-09-19. PMID:24269730. |
fluoxetine in adulthood normalizes gaba release and rescues hippocampal synaptic plasticity and spatial memory in a mouse model of down syndrome. |
2014-09-19 |
2023-08-12 |
mouse |
| Tatjana Begenisic, Laura Baroncelli, Gabriele Sansevero, Marco Milanese, Tiziana Bonifacino, Giambattista Bonanno, Giovanni Cioni, Lamberto Maffei, Alessandro Sal. Fluoxetine in adulthood normalizes GABA release and rescues hippocampal synaptic plasticity and spatial memory in a mouse model of Down syndrome. Neurobiology of disease. vol 63. 2014-09-19. PMID:24269730. |
here we employed a multidisciplinary approach spanning from the behavioral to the electrophysiological and molecular level to investigate the effects elicited by fluoxetine on cognitive abilities, hippocampal synaptic plasticity and gaba release in adult ts65dn mice. |
2014-09-19 |
2023-08-12 |
mouse |
| Tatjana Begenisic, Laura Baroncelli, Gabriele Sansevero, Marco Milanese, Tiziana Bonifacino, Giambattista Bonanno, Giovanni Cioni, Lamberto Maffei, Alessandro Sal. Fluoxetine in adulthood normalizes GABA release and rescues hippocampal synaptic plasticity and spatial memory in a mouse model of Down syndrome. Neurobiology of disease. vol 63. 2014-09-19. PMID:24269730. |
we report that a chronic treatment with fluoxetine administered in the drinking water normalizes gaba release and promotes recovery of spatial memory abilities, spatial working memory for alternation, and hippocampal synaptic plasticity in adult ts65dn mice. |
2014-09-19 |
2023-08-12 |
mouse |
| Lorena C L R Santana, Maria R M Brito, George L S Oliveira, Antônia M G L Citó, Clayton Q Alves, Juceni P David, Jorge M David, Rivelilson M de Freita. Mikania glomerata: Phytochemical, Pharmacological, and Neurochemical Study. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-09-09. PMID:25202336. |
this extract demonstrated anxiolytic effects, which may be mediated by gabaergic system, and was able to increase gaba levels and reduce of glutamate and aspartate concentrations in mice hippocampus, which can directly and/or indirectly assist in their anxiolytic effect. |
2014-09-09 |
2023-08-13 |
mouse |
| Pishan Chang, Matthew C Walker, Robin S B William. Seizure-induced reduction in PIP3 levels contributes to seizure-activity and is rescued by valproic acid. Neurobiology of disease. vol 62. 2014-09-03. PMID:24148856. |
these finding were reproduced in cultured rat hippocampal primary neurons and entorhinal cortex-hippocampal slices during exposure to the gaba(a) receptor antagonist pentylenetetrazol (ptz), which is widely used to generate seizures and seizure-like (paroxysmal) activity. |
2014-09-03 |
2023-08-12 |
rat |
| Sebastian H Bitzenhofer, Ileana L Hanganu-Opat. Oscillatory coupling within neonatal prefrontal-hippocampal networks is independent of selective removal of GABAergic neurons in the hippocampus. Neuropharmacology. vol 77. 2014-08-26. PMID:24056266. |
here, we used saporin-conjugated anti-vesicular gaba transporter antibodies to cause selective immunotoxic lesion of gabaergic neurons in the ca1 area of the hippocampus during the first postnatal week. |
2014-08-26 |
2023-08-12 |
rat |
| Eiichi Maru, Hiroyuki Ur. [GABA(A) receptor trafficking and epilepsy]. Nihon rinsho. Japanese journal of clinical medicine. vol 72. issue 5. 2014-08-26. PMID:24912277. |
in status epilepticus, furthermore, the hippocampal gaba(a) receptor beta3 subunits were significantly disphosphorylated, resulting in a facilitation of the endocytosis of gaba(a) receptors and reduced benzodiazepine sensitivity. |
2014-08-26 |
2023-08-13 |
Not clear |