| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Q Long, Y Hei, Q Luo, Y Tian, J Yang, J Li, L Wei, W Li. BMSCs transplantation improves cognitive impairment via up-regulation of hippocampal GABAergic system in a rat model of chronic cerebral hypoperfusion. Neuroscience. vol 311. 2016-09-14. PMID:26545982. |
it is considered that the hippocampus holds the capabilities of memory consolidation and spatial navigation, and the gamma amino butyric acid (gaba)ergic system plays an important role in the control of learning and memory processes. |
2016-09-14 |
2023-08-13 |
rat |
| Q Long, Y Hei, Q Luo, Y Tian, J Yang, J Li, L Wei, W Li. BMSCs transplantation improves cognitive impairment via up-regulation of hippocampal GABAergic system in a rat model of chronic cerebral hypoperfusion. Neuroscience. vol 311. 2016-09-14. PMID:26545982. |
four weeks later, the morris water maze was employed to evaluate the cognitive changes of each group, immunohistochemistry and western blotting was used to investigate the gabaergic system expression including gaba, glutamic acid decarboxylase 67 (gad67) or gaba(b) receptor 1 (gaba(b)r1) in the hippocampus. |
2016-09-14 |
2023-08-13 |
rat |
| Erica R Glasper, Elizabeth A LaMarca, Miriam E Bocarsly, Maria Fasolino, Maya Opendak, Elizabeth Goul. Sexual experience enhances cognitive flexibility and dendritic spine density in the medial prefrontal cortex. Neurobiology of learning and memory. vol 125. 2016-09-09. PMID:26188276. |
as a first attempt at investigating this, we inactivated the ventral hippocampus with the gaba agonist muscimol, after each daily bout of sexual experience to observe whether the beneficial effects on cognitive flexibility were abolished. |
2016-09-09 |
2023-08-13 |
rat |
| Cesar E Santana-Gomez, David Alcantara-Gonzalez, Hiram Luna-Munguia, Ivette Banuelos-Cabrera, Victor Magdaleno-Madrigal, Michael Tamayo, Luisa L Rocha, Walter G Besi. Transcranial focal electrical stimulation reduces seizure activity and hippocampal glutamate release during status epilepticus. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2015. 2016-09-02. PMID:26737802. |
the aim of the present study was to evaluate the effects of tfs on γ-aminobutyric acid (gaba) and glutamate release in the hippocampus during pilocarpine-induced se. |
2016-09-02 |
2023-08-13 |
rat |
| Cesar E Santana-Gomez, David Alcantara-Gonzalez, Hiram Luna-Munguia, Ivette Banuelos-Cabrera, Victor Magdaleno-Madrigal, Michael Tamayo, Luisa L Rocha, Walter G Besi. Transcranial focal electrical stimulation reduces seizure activity and hippocampal glutamate release during status epilepticus. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2015. 2016-09-02. PMID:26737802. |
these effects were associated with lower release of gaba and glutamate in the hippocampus. |
2016-09-02 |
2023-08-13 |
rat |
| Sandra Henriques Vaz, Sofia Rapaz Lérias, Sara Parreira, Maria José Diógenes, Ana Maria Sebastiã. Adenosine A2A receptor activation is determinant for BDNF actions upon GABA and glutamate release from rat hippocampal synaptosomes. Purinergic signalling. vol 11. issue 4. 2016-08-29. PMID:26452489. |
adenosine a2a receptor activation is determinant for bdnf actions upon gaba and glutamate release from rat hippocampal synaptosomes. |
2016-08-29 |
2023-08-13 |
rat |
| Sandra Henriques Vaz, Sofia Rapaz Lérias, Sara Parreira, Maria José Diógenes, Ana Maria Sebastiã. Adenosine A2A receptor activation is determinant for BDNF actions upon GABA and glutamate release from rat hippocampal synaptosomes. Purinergic signalling. vol 11. issue 4. 2016-08-29. PMID:26452489. |
we thus evaluated the role of a(2a)r on the modulatory effect of bdnf upon glutamate and gaba release from isolated hippocampal nerve terminals (synaptosomes). |
2016-08-29 |
2023-08-13 |
rat |
| Do-Wan Lee, Seockhoon Chung, Hyun Ju Yoo, Su Jung Kim, Chul-Woong Woo, Sang-Tae Kim, Dong-Hoon Lee, Kyung Won Kim, Jeong-Kon Kim, Jin Seong Lee, Choong Gon Choi, Woo Hyun Shim, Yoonseok Choi, Dong-Cheol Wo. Neurochemical Changes Associated with Stress-Induced Sleep Disturbance in Rats: In Vivo and In Vitro Measurements. PloS one. vol 11. issue 4. 2016-08-26. PMID:27078855. |
in the right dorsal hippocampal region, the gamma-aminobutyric-acid (gaba) and glutamine (gln) concentrations were significantly higher in the sleep-perturbed rats than in the sham controls. |
2016-08-26 |
2023-08-13 |
human |
| Jérôme Mairesse, Eleonora Gatta, Marie-Line Reynaert, Jordan Marrocco, Sara Morley-Fletcher, Marion Soichot, Lucie Deruyter, Gilles Van Camp, Hammou Bouwalerh, Francesca Fagioli, Anna Pittaluga, Delphine Allorge, Ferdinando Nicoletti, Stefania Maccar. Activation of presynaptic oxytocin receptors enhances glutamate release in the ventral hippocampus of prenatally restraint stressed rats. Psychoneuroendocrinology. vol 62. 2016-08-24. PMID:26231445. |
here, we have found that activation of presynaptic oxytocin receptor with the potent agonist, carbetocin, enhanced depolarization-evoked glutamate release in the ventral hippocampus with no effect on gaba release. |
2016-08-24 |
2023-08-13 |
rat |
| Giovanni Provenzano, Paola Sgadò, Sacha Genovesi, Giulia Zunino, Simona Casarosa, Yuri Bozz. Hippocampal dysregulation of FMRP/mGluR5 signaling in engrailed-2 knockout mice: a model of autism spectrum disorders. Neuroreport. vol 26. issue 18. 2016-08-23. PMID:26559723. |
here, we exploited en2(-/-) mice to investigate hippocampal expression of fmrp, mglur5, and gaba(a) receptor β3 subunit (gabrb3). |
2016-08-23 |
2023-08-13 |
mouse |
| M Dolores Muñoz, Mónica Antolín-Vallespín, Silvia Tapia-González, Amelia Sánchez-Capel. Smad3 deficiency inhibits dentate gyrus LTP by enhancing GABAA neurotransmission. Journal of neurochemistry. vol 137. issue 2. 2016-08-22. PMID:26826552. |
moreover, there is no difference in the hippocampal gad65 and gad67 content, suggesting that gaba biosynthesis remains unaffected. |
2016-08-22 |
2023-08-13 |
mouse |
| M Dolores Muñoz, Mónica Antolín-Vallespín, Silvia Tapia-González, Amelia Sánchez-Capel. Smad3 deficiency inhibits dentate gyrus LTP by enhancing GABAA neurotransmission. Journal of neurochemistry. vol 137. issue 2. 2016-08-22. PMID:26826552. |
alteration of gaba neurotransmission is thought to produce hippocampal cognitive dysfunction in down's syndrome or alzheimer's disease, and here we provide new insights into the hippocampal changes in an animal model of parkinson's disease. |
2016-08-22 |
2023-08-13 |
mouse |
| Li Liu, Chang-jun Li, Yun Lu, Xian-gang Zong, Chao Luo, Jun Sun, Lian-jun Gu. Baclofen mediates neuroprotection on hippocampal CA1 pyramidal cells through the regulation of autophagy under chronic cerebral hypoperfusion. Scientific reports. vol 5. 2016-08-19. PMID:26412641. |
however, during chronic cerebral hypoperfusion, the changes of autophagy in the hippocampal ca1 area, the correlation between gaba receptors and autophagy, and their influences on hippocampal neuronal apoptosis have not been well established. |
2016-08-19 |
2023-08-13 |
rat |
| Xueyan Zhou, Qiuxiang Zhu, Xiaowen Han, Renguo Chen, Yaowu Liu, Hongbin Fan, Xiaoxing Yi. Quantitative-profiling of neurotransmitter abnormalities in the disease progression of experimental diabetic encephalopathy rat. Canadian journal of physiology and pharmacology. vol 93. issue 11. 2016-08-18. PMID:26426748. |
as for γ-aminobutyric acid (gaba), it was down-regulated in serum, but up-regulated in csf, hippocampus, and the cortex in the stz-treated group. |
2016-08-18 |
2023-08-13 |
rat |
| Yukitoshi Izumi, Charles F Zorumsk. GABA and Endocannabinoids Mediate Depotentiation of Schaffer Collateral Synapses Induced by Stimulation of Temperoammonic Inputs. PloS one. vol 11. issue 2. 2016-07-25. PMID:26862899. |
in the present study, we used rat hippocampal slices to explore other messengers contributing to ta-induced sc depotentiation, and provide evidence for the involvement of cannabinoid-1 and γ-aminobutyric acid (gaba) type-a receptors as more proximal signaling events leading to synaptic resetting, with a1 receptor activation serving as a downstream event. |
2016-07-25 |
2023-08-13 |
rat |
| Lucian Medrihan, Enrico Ferrea, Barbara Greco, Pietro Baldelli, Fabio Benfenat. Asynchronous GABA Release Is a Key Determinant of Tonic Inhibition and Controls Neuronal Excitability: A Study in the Synapsin II-/- Mouse. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 10. 2016-07-20. PMID:24962993. |
we show that deletion of synapsin ii (syn ii), a presynaptic protein contributing to epilepsy predisposition in humans, leads to a loss of tonic inhibition in mouse hippocampal slices due to a dramatic decrease in presynaptic asynchronous gaba release. |
2016-07-20 |
2023-08-13 |
mouse |
| Mats Julius Stensrud, Carl Johan Sogn, Vidar Gunderse. Immunogold characteristics of VGLUT3-positive GABAergic nerve terminals suggest corelease of glutamate. The Journal of comparative neurology. vol 523. issue 18. 2016-07-20. PMID:26010578. |
we have previously shown that vglut3 is found together with the vesicular gaba transporter (viaat) on synaptic vesicle membranes in the hippocampus. |
2016-07-20 |
2023-08-13 |
rat |
| Mats Julius Stensrud, Carl Johan Sogn, Vidar Gunderse. Immunogold characteristics of VGLUT3-positive GABAergic nerve terminals suggest corelease of glutamate. The Journal of comparative neurology. vol 523. issue 18. 2016-07-20. PMID:26010578. |
the analyses suggest that glutamate is coreleased with gaba from hippocampal basket cell-synapses to act on nmda receptors. |
2016-07-20 |
2023-08-13 |
rat |
| Jason J Radley, Paul E Sawchenk. Evidence for involvement of a limbic paraventricular hypothalamic inhibitory network in hypothalamic-pituitary-adrenal axis adaptations to repeated stress. The Journal of comparative neurology. vol 523. issue 18. 2016-07-20. PMID:26010947. |
we previously identified a circumscribed, anterior part of the bed nuclei of the stria terminalis (abst) that houses stress-sensitive, pvh-projecting, γ-aminobutyric acid (gaba)-ergic neurons as representing a site of convergence of stress-inhibitory influences originating from medial prefrontal and hippocampal cortices. |
2016-07-20 |
2023-08-13 |
rat |
| Paula Valente-Silva, Cristina Lemos, Attila Köfalvi, Rodrigo A Cunha, John G Jone. Ketone bodies effectively compete with glucose for neuronal acetyl-CoA generation in rat hippocampal slices. NMR in biomedicine. vol 28. issue 9. 2016-07-19. PMID:26174755. |
hence, the contributions of exogenous 5.0 mm [1-(13)c]glucose and 1.0 mm [2-(13)c]lactate + 0.1 mm pyruvate (combined [2-(13)c]lactate + [2-(13)c]pyruvate) to acetyl-coa production were measured both without and with 5.0 mm [u-(13)c]3-hydroxybutyrate in superfused rat hippocampal slices by (13)c nmr non-steady-state isotopomer analysis of tissue glutamate and gaba. |
2016-07-19 |
2023-08-13 |
rat |