| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Barbieri, A Ossato, I Canazza, C Trapella, A C Borelli, S Beggiato, C Rimondo, G Serpelloni, L Ferraro, M Mart. Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence. Neuropharmacology. vol 109. 2017-06-19. PMID:27346209. |
moreover, in vitro studies showed as jwh-018-r compounds negatively affected electrically evoked synaptic transmission, ltp and aminoacid (glutamate and gaba) release in hippocampal slices. |
2017-06-19 |
2023-08-13 |
mouse |
| Teri M Furlong, Jhodie R Duncan, Laura H Corbit, Caroline D Rae, Benjamin D Rowlands, Anthony D Maher, Fatima A Nasrallah, Carol J Milligan, Steven Petrou, Andrew J Lawrence, Bernard W Ballein. Toluene inhalation in adolescent rats reduces flexible behaviour in adulthood and alters glutamatergic and GABAergic signalling. Journal of neurochemistry. vol 139. issue 5. 2017-06-14. PMID:27696399. |
these behavioural deficits were accompanied by changes in subunit expression of both nmda and gaba receptors in adulthood, up to 10 weeks after the final exposure to toluene in the hippocampus, prefrontal cortex and ventromedial striatum; regions with recognized roles in behavioural flexibility and decision-making. |
2017-06-14 |
2023-08-13 |
rat |
| Tao Liu, Hongyu Li, Wanjin Hong, Weiping Ha. Brefeldin A-inhibited guanine nucleotide exchange protein 3 is localized in lysosomes and regulates GABA signaling in hippocampal neurons. Journal of neurochemistry. vol 139. issue 5. 2017-06-14. PMID:27696409. |
brefeldin a-inhibited guanine nucleotide exchange protein 3 is localized in lysosomes and regulates gaba signaling in hippocampal neurons. |
2017-06-14 |
2023-08-13 |
mouse |
| Diogo M Rombo, Joaquim A Ribeiro, Ana M Sebastiã. Hippocampal GABAergic transmission: a new target for adenosine control of excitability. Journal of neurochemistry. vol 139. issue 6. 2017-06-14. PMID:27778347. |
physiological network functioning in the hippocampus is dependent on a balance between glutamatergic cell excitability and the activity of diverse local circuit neurons that release the inhibitory neurotransmitter γ-aminobutyric acid (gaba). |
2017-06-14 |
2023-08-13 |
Not clear |
| Johannes van Brederode, Sinem Atak, Artur Kessler, Monika Pischetsrieder, Carmen Villmann, Christian Alzheime. The terpenoids Myrtenol and Verbenol act on δ subunit-containing GABAA receptors and enhance tonic inhibition in dentate gyrus granule cells. Neuroscience letters. vol 628. 2017-06-13. PMID:27312536. |
consistent with their effects on heterologous α1β2γ2 receptors, we found that myrtenol and verbenol, when co-applied with gaba via local perfusion, increased the amplitude and area of miniature inhibitory postsynaptic potentials (mipscs) recorded in whole-cell voltage-clamp recordings from granule cells in the dentate gyrus of mouse hippocampal brain slices. |
2017-06-13 |
2023-08-13 |
mouse |
| Murui Han, JuOae Chang, Jonghan Ki. Loss of divalent metal transporter 1 function promotes brain copper accumulation and increases impulsivity. Journal of neurochemistry. vol 138. issue 6. 2017-06-13. PMID:27331785. |
impaired emotional behavior was associated with down-regulation of gaba in the hippocampus in b/b rats. |
2017-06-13 |
2023-08-13 |
human |
| Xiaoguang Li, Zhihao Wang, Lu Tan, Yali Wang, Chengbiao Lu, Rongxiang Chen, Shujuan Zhang, Yuan Gao, Yanchao Liu, Yaling Yin, Xinghua Liu, Enjie Liu, Ying Yang, Yu Hu, Zhipeng Xu, Fuqiang Xu, Jie Wang, Gong-Ping Liu, Jian-Zhi Wan. Correcting miR92a-vGAT-Mediated GABAergic Dysfunctions Rescues Human Tau-Induced Anxiety in Mice. Molecular therapy : the journal of the American Society of Gene Therapy. vol 25. issue 1. 2017-06-06. PMID:28129110. |
here, we found that overexpression of human wild-type, full-length tau (termed htau) in hippocampus significantly decreased the extracellular γ-aminobutyric acid (gaba) level with inhibition of γ oscillation and the evoked inhibitory postsynaptic potential (eipsp). |
2017-06-06 |
2023-08-13 |
mouse |
| Haining Yu, Tao Chen, Li Zhou, Jiyou Tan. Effect of Selective 5-HT6R Agonist on Expression of 5-HT Receptor and Neurotransmitter in Vascular Dementia Rats. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2017-05-25. PMID:28196966. |
brains were extracted to separate the cortex and hippocampal tissues, in which glutamate and g-aminobutyric acid (gaba) levels were analyzed. |
2017-05-25 |
2023-08-13 |
rat |
| Haining Yu, Tao Chen, Li Zhou, Jiyou Tan. Effect of Selective 5-HT6R Agonist on Expression of 5-HT Receptor and Neurotransmitter in Vascular Dementia Rats. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2017-05-25. PMID:28196966. |
contents of da, glu, gaba, and ach were lowered in cortical and hippocampal tissues, and 5-ht6r expression was suppressed (p<0.05). |
2017-05-25 |
2023-08-13 |
rat |
| Susumu It. GABA and glycine in the developing brain. The journal of physiological sciences : JPS. vol 66. issue 5. 2017-05-09. PMID:26951057. |
gaba and glycine are involved in spontaneous neural network activities in the immature cns such as giant depolarizing potentials (gdps) in neonatal hippocampal neurons, which are generated by the synchronous activity of gabaergic interneurons and glutamatergic principal neurons. |
2017-05-09 |
2023-08-13 |
Not clear |
| Noha F Abdelkader, Muhammed A Saad, Rania M Abdelsala. Neuroprotective effect of nebivolol against cisplatin-associated depressive-like behavior in rats. Journal of neurochemistry. vol 141. issue 3. 2017-05-02. PMID:28178754. |
in parallel, cisplatin administration prominently reduced gaba and elevated glutamate levels in the cortical and hippocampal tissues. |
2017-05-02 |
2023-08-13 |
rat |
| Corwin R Butler, Jeffery A Boychuk, Bret N Smit. Differential effects of rapamycin treatment on tonic and phasic GABAergic inhibition in dentate granule cells after focal brain injury in mice. Experimental neurology. vol 280. 2017-04-28. PMID:27018320. |
inhibitory synaptic signaling in the hippocampus is predominately driven by γ-aminobutyric acid (gaba) neurotransmission, and is prominently mediated by postsynaptic type a gaba receptors (gabaar's). |
2017-04-28 |
2023-08-13 |
mouse |
| M Haidar, G Guèvremont, C Zhang, R A D Bathgate, E Timofeeva, C M Smith, A L Gundlac. Relaxin-3 inputs target hippocampal interneurons and deletion of hilar relaxin-3 receptors in "floxed-RXFP3" mice impairs spatial memory. Hippocampus. vol 27. issue 5. 2017-04-25. PMID:28100033. |
hippocampus is innervated by γ-aminobutyric acid (gaba) "projection" neurons of the nucleus incertus (ni), including a population expressing the neuropeptide, relaxin-3 (rln3). |
2017-04-25 |
2023-08-13 |
mouse |
| Martin J Brodie, Frank Besag, Alan B Ettinger, Marco Mula, Gabriella Gobbi, Stefano Comai, Albert P Aldenkamp, Bernhard J Steinhof. Epilepsy, Antiepileptic Drugs, and Aggression: An Evidence-Based Review. Pharmacological reviews. vol 68. issue 3. 2017-04-20. PMID:27255267. |
we review the common neurotransmitter systems and brain regions implicated in both epilepsy and aggression, including the gaba, glutamate, serotonin, dopamine, and noradrenaline systems and the hippocampus, amygdala, prefrontal cortex, anterior cingulate cortex, and temporal lobes. |
2017-04-20 |
2023-08-13 |
Not clear |
| Masoumeh Sarfi, Mahmoud Elahdadi Salmani, Iran Goudarzi, Taghi Lashkar Boluki, Kataneh Abrar. Evaluating the role of astrocytes on β-estradiol effect on seizures of Pilocarpine epileptic model. European journal of pharmacology. vol 797. 2017-04-07. PMID:28088383. |
moreover, hippocampal glutamate and gaba were evaluated to study excitability changes. |
2017-04-07 |
2023-08-13 |
rat |
| Angela L Cumberland, Hannah K Palliser, Gabrielle K Crombie, David W Walker, Jonathan J Hirs. Increased anxiety-like phenotype in female guinea pigs following reduced neurosteroid exposure in utero. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 58. 2017-03-29. PMID:28192175. |
male and female offspring from vehicle and finasteride treated dams were tested at postnatal day 20 (juvenile-equivalence) in an open field arena, and hippocampus and amygdala subsequently assessed for neurological changes in markers of development and gaba production pathways 24h later. |
2017-03-29 |
2023-08-13 |
Not clear |
| S Mataradze, T Naneishvili, M Sephashvili, D Mikeladze, M Dashnian. EFFECTS OF MEDIAL SEPTAL LESION ON HIPPOCAMPAL EXTRACELLULAR GLUTAMATE AND GABA LEVELS DURING SPATIAL ALTERNATION TESTING. Georgian medical news. issue 259. 2017-03-24. PMID:27845295. |
effects of medial septal lesion on hippocampal extracellular glutamate and gaba levels during spatial alternation testing. |
2017-03-24 |
2023-08-13 |
rat |
| S Mataradze, T Naneishvili, M Sephashvili, D Mikeladze, M Dashnian. EFFECTS OF MEDIAL SEPTAL LESION ON HIPPOCAMPAL EXTRACELLULAR GLUTAMATE AND GABA LEVELS DURING SPATIAL ALTERNATION TESTING. Georgian medical news. issue 259. 2017-03-24. PMID:27845295. |
the present study investigated spatial working memory assessed in spontaneous alternation (sa) task and hippocampal glutamate and gaba release prior to, during, and after sa test in sham-operated and electrolytic medial septal (ms) lesioned rats. |
2017-03-24 |
2023-08-13 |
rat |
| S Mataradze, T Naneishvili, M Sephashvili, D Mikeladze, M Dashnian. EFFECTS OF MEDIAL SEPTAL LESION ON HIPPOCAMPAL EXTRACELLULAR GLUTAMATE AND GABA LEVELS DURING SPATIAL ALTERNATION TESTING. Georgian medical news. issue 259. 2017-03-24. PMID:27845295. |
also, have been investigated the effects of ms lesion on kcl-stimulated release of glutamate and gaba in the hippocampus. |
2017-03-24 |
2023-08-13 |
rat |
| S Mataradze, T Naneishvili, M Sephashvili, D Mikeladze, M Dashnian. EFFECTS OF MEDIAL SEPTAL LESION ON HIPPOCAMPAL EXTRACELLULAR GLUTAMATE AND GABA LEVELS DURING SPATIAL ALTERNATION TESTING. Georgian medical news. issue 259. 2017-03-24. PMID:27845295. |
hippocampal gaba levels did not change during behavioral testing in both groups. |
2017-03-24 |
2023-08-13 |
rat |