| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Subburaju, A J Coleman, W B Ruzicka, F M Bene. Toward dissecting the etiology of schizophrenia: HDAC1 and DAXX regulate GAD67 expression in an in vitro hippocampal GABA neuron model. Translational psychiatry. vol 6. 2016-10-17. PMID:26812044. |
schizophrenia (sz) is associated with gaba neuron dysfunction in the hippocampus, particularly the stratum oriens of sector ca3/2. |
2016-10-17 |
2023-08-13 |
human |
| S Subburaju, A J Coleman, W B Ruzicka, F M Bene. Toward dissecting the etiology of schizophrenia: HDAC1 and DAXX regulate GAD67 expression in an in vitro hippocampal GABA neuron model. Translational psychiatry. vol 6. 2016-10-17. PMID:26812044. |
in the hippocampal gaba neuron culture model, hib5, transduction with hdac1 shrnai showed a 40% inhibition of hdac1 mrna and a 60% inhibition of hdac1 protein. |
2016-10-17 |
2023-08-13 |
human |
| Marco Fuenzalida, Claudia Espinoza, Miguel Ángel Pérez, Cheril Tapia-Rojas, Loreto Cuitino, Enrique Brandan, Nibaldo C Inestros. Wnt signaling pathway improves central inhibitory synaptic transmission in a mouse model of Duchenne muscular dystrophy. Neurobiology of disease. vol 86. 2016-10-14. PMID:26626079. |
the dystrophin-deficient (mdx) mouse model of duchenne muscular dystrophy (dmd) exhibits a significant reduction in hippocampal gaba efficacy, which may underlie the altered synaptic function and abnormal hippocampal long-term plasticity exhibited by mdx mice. |
2016-10-14 |
2023-08-13 |
mouse |
| Marco Fuenzalida, Claudia Espinoza, Miguel Ángel Pérez, Cheril Tapia-Rojas, Loreto Cuitino, Enrique Brandan, Nibaldo C Inestros. Wnt signaling pathway improves central inhibitory synaptic transmission in a mouse model of Duchenne muscular dystrophy. Neurobiology of disease. vol 86. 2016-10-14. PMID:26626079. |
we report here that the activation of the non-canonical wnt-5a pathway and andrographolide, improves hippocampal mdx gabaergic efficacy by increasing the number of inhibitory synapses and gaba(a) receptors or gaba release. |
2016-10-14 |
2023-08-13 |
mouse |
| Andrew Hooper, Jamie Maguir. Characterization of a novel subtype of hippocampal interneurons that express corticotropin-releasing hormone. Hippocampus. vol 26. issue 1. 2016-10-13. PMID:26135556. |
these hippocampal crh neurons express both gaba and gad67 and using in vitro optogenetic techniques, we demonstrate that these neurons make functional connections and release gaba onto ca3 principal neurons. |
2016-10-13 |
2023-08-13 |
mouse |
| Nicolas Toni, Alejandro F Schinde. Maturation and Functional Integration of New Granule Cells into the Adult Hippocampus. Cold Spring Harbor perspectives in biology. vol 8. issue 1. 2016-10-13. PMID:26637288. |
the adult hippocampus generates functional dentate granule cells (gcs) that release glutamate onto target cells in the hilus and cornus ammonis (ca)3 region, and receive glutamatergic and γ-aminobutyric acid (gaba)ergic inputs that tightly control their spiking activity. |
2016-10-13 |
2023-08-13 |
Not clear |
| Koichi Inoue, Yasuto Miyazaki, Keiko Unno, Jun Zhe Min, Kenichiro Todoroki, Toshimasa Toyo'ok. Stable isotope dilution HILIC-MS/MS method for accurate quantification of glutamic acid, glutamine, pyroglutamic acid, GABA and theanine in mouse brain tissues. Biomedical chromatography : BMC. vol 30. issue 1. 2016-10-05. PMID:26033549. |
for application of the theanine intake, the determination of glu, gln, pglu, gaba and theanine in the hippocampus and central cortex tissues was performed based on our developed method. |
2016-10-05 |
2023-08-13 |
mouse |
| Vicente Hernández-Rabaza, Andrea Cabrera-Pastor, Lucas Taoro-González, Michele Malaguarnera, Ana Agustí, Marta Llansola, Vicente Felip. Hyperammonemia induces glial activation, neuroinflammation and alters neurotransmitter receptors in hippocampus, impairing spatial learning: reversal by sulforaphane. Journal of neuroinflammation. vol 13. 2016-10-05. PMID:26883214. |
two main aims of this work were: (1) to assess whether chronic hyperammonemia increases inflammatory factors in the hippocampus and if this is associated with microglia and/or astrocytes activation and (2) to assess whether hyperammonemia-induced neuroinflammation in the hippocampus is associated with altered membrane expression of glutamate and gaba receptors and spatial learning impairment. |
2016-10-05 |
2023-08-13 |
rat |
| Masoumeh Nazari, Alireza Komaki, Ruhollah Karamian, Siamak Shahidi, Abdolrahman Sarihi, Masoumeh Asadbeg. The interactive role of CB(1) and GABA(B) receptors in hippocampal synaptic plasticity in rats. Brain research bulletin. vol 120. 2016-09-30. PMID:26611204. |
the interactive role of cb(1) and gaba(b) receptors in hippocampal synaptic plasticity in rats. |
2016-09-30 |
2023-08-13 |
rat |
| Masoumeh Nazari, Alireza Komaki, Ruhollah Karamian, Siamak Shahidi, Abdolrahman Sarihi, Masoumeh Asadbeg. The interactive role of CB(1) and GABA(B) receptors in hippocampal synaptic plasticity in rats. Brain research bulletin. vol 120. 2016-09-30. PMID:26611204. |
gaba receptor type b (gabab) and cannabinoid receptor type 1 (cb1) exhibit overlapping anatomical localization in some brain areas including the hippocampus. |
2016-09-30 |
2023-08-13 |
rat |
| Yun Wang, Javed Iqbal, Yahui Liu, Rui Su, Song Lu, Guang Peng, Yongqian Zhang, Hong Qing, Yulin Den. Effects of simulated microgravity on the expression of presynaptic proteins distorting the GABA/glutamate equilibrium--A proteomics approach. Proteomics. vol 15. issue 22. 2016-09-21. PMID:26359799. |
sm decreased the content of γ-aminobutyric acid (gaba) and increased the content of glutamate (glu) in the rat hippocampus. |
2016-09-21 |
2023-08-13 |
rat |
| Ming Lei, Huixin Xu, Zhangyuan Li, Zemin Wang, Tiernan T O'Malley, Dainan Zhang, Dominic M Walsh, Pingyi Xu, Dennis J Selkoe, Shaomin L. Soluble Aβ oligomers impair hippocampal LTP by disrupting glutamatergic/GABAergic balance. Neurobiology of disease. vol 85. 2016-09-21. PMID:26525100. |
decreasing neuronal activity by increasing gaba tone or partially blocking nmdar activity prevented oaβ impairment of hippocampal ltp. |
2016-09-21 |
2023-08-13 |
mouse |
| Rafael M Bitencourt, Alán Alpár, Valentina Cinquina, Samira G Ferreira, Bárbara S Pinheiro, Cristina Lemos, Catherine Ledent, Reinaldo N Takahashi, Fernando J Sialana, Gert Lubec, Rodrigo A Cunha, Tibor Harkany, Attila Köfalv. Lack of presynaptic interaction between glucocorticoid and CB1 cannabinoid receptors in GABA- and glutamatergic terminals in the frontal cortex of laboratory rodents. Neurochemistry international. vol 90. 2016-09-20. PMID:26196379. |
additional confocal microscopy analysis of cortical and hippocampal regions revealed vesicular gaba transporter-positive and vesicular glutamate transporter 1-positive nerve terminals endowed with cb1r immunoreactivity, apposing gcr-positive post-synaptic compartments. |
2016-09-20 |
2023-08-13 |
mouse |
| Zsolt Bagosi, Beáta Balangó, Dávid Pintér, Krisztina Csabafi, Miklós Jászberényi, Gyula Szabó, Gyula Telegd. The effects of CRF and urocortins on the hippocampal glutamate release. Neurochemistry international. vol 90. 2016-09-20. PMID:26216727. |
the urocortins (ucn i, ucn ii and ucn iii) are crf-related peptides, which may also regulate the hpa axis directly or indirectly, by modulation of extrahypothalamic neurotransmitters, such as amygdalar gaba and hippocampal glutamate. |
2016-09-20 |
2023-08-13 |
rat |
| Zsolt Bagosi, Beáta Balangó, Dávid Pintér, Krisztina Csabafi, Miklós Jászberényi, Gyula Szabó, Gyula Telegd. The effects of CRF and urocortins on the hippocampal glutamate release. Neurochemistry international. vol 90. 2016-09-20. PMID:26216727. |
based on the previous and the present results we conclude that crfr1 agonists can activate the hpa axis not only directly, but also indirectly by increasing the amygdalar gaba release and decreasing the hippocampal glutamate release. |
2016-09-20 |
2023-08-13 |
rat |
| Jinwook Kim, Yeonghoon Son, Juhwan Kim, Sueun Lee, Sohi Kang, Kyunghwan Park, Sung-Ho Kim, Jong-Choon Kim, Jeongtae Kim, Chitoshi Takayama, Heh-In Im, Miyoung Yang, Taekyun Shin, Changjong Moo. Developmental and degenerative modulation of GABAergic transmission in the mouse hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 47. issue Pt B. 2016-09-16. PMID:26394279. |
the goal of the present study was to understand the developmental and degenerative regulation of gabaergic transmission in the mouse hippocampus by examining changes in gaba receptor subunit mrna levels and gaba-related protein expression during postnatal development of the hippocampus and trimethyltin (tmt)-induced neurodegeneration in the juvenile (postnatal day [pd] 24) and adult hippocampus (pd 56). |
2016-09-16 |
2023-08-13 |
mouse |
| Jinwook Kim, Yeonghoon Son, Juhwan Kim, Sueun Lee, Sohi Kang, Kyunghwan Park, Sung-Ho Kim, Jong-Choon Kim, Jeongtae Kim, Chitoshi Takayama, Heh-In Im, Miyoung Yang, Taekyun Shin, Changjong Moo. Developmental and degenerative modulation of GABAergic transmission in the mouse hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 47. issue Pt B. 2016-09-16. PMID:26394279. |
during postnatal development, the mrna levels of gaba a receptor (gabaar) subunits, including α1, α4, β1, β2, and δ; gaba b receptor (gababr) subunit 2; and the expression of gaba-related proteins, including glutamic acid decarboxylase, vesicular gaba transporter (vgat), and potassium chloride cotransporter 2 increased gradually in the mouse hippocampus. |
2016-09-16 |
2023-08-13 |
mouse |
| Jinwook Kim, Yeonghoon Son, Juhwan Kim, Sueun Lee, Sohi Kang, Kyunghwan Park, Sung-Ho Kim, Jong-Choon Kim, Jeongtae Kim, Chitoshi Takayama, Heh-In Im, Miyoung Yang, Taekyun Shin, Changjong Moo. Developmental and degenerative modulation of GABAergic transmission in the mouse hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 47. issue Pt B. 2016-09-16. PMID:26394279. |
the mrna levels of most gaba receptor subunits in the juvenile hippocampus, excluding gabaar subunit β3, were dynamically altered after tmt treatment. |
2016-09-16 |
2023-08-13 |
mouse |
| Tomasz Boczek, Malwina Lisek, Bozena Ferenc, Magdalena Wiktorska, Ivana Ivchevska, Ludmila Zylinsk. Region-specific effects of repeated ketamine administration on the presynaptic GABAergic neurochemistry in rat brain. Neurochemistry international. vol 91. 2016-09-15. PMID:26492822. |
for 5 days, and next we analyzed gaba metabolizing enzymes in cortex, cerebellum, hippocampus and striatum. |
2016-09-15 |
2023-08-13 |
rat |
| Tomasz Boczek, Malwina Lisek, Bozena Ferenc, Magdalena Wiktorska, Ivana Ivchevska, Ludmila Zylinsk. Region-specific effects of repeated ketamine administration on the presynaptic GABAergic neurochemistry in rat brain. Neurochemistry international. vol 91. 2016-09-15. PMID:26492822. |
consecutively, reduction in glutamate decarboxylase activity and gaba concentration were detected in cortex, cerebellum and striatum, but not in hippocampus. |
2016-09-15 |
2023-08-13 |
rat |