| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tobias Bast, Marie Pezze, Stephanie McGarrit. Cognitive deficits caused by prefrontal cortical and hippocampal neural disinhibition. British journal of pharmacology. vol 174. issue 19. 2018-05-22. PMID:28477384. |
recent studies in rats showed that prefrontal and hippocampal neural disinhibition (by local gaba antagonist microinfusion) dysregulates burst firing, which has been associated with important aspects of neural information processing. |
2018-05-22 |
2023-08-13 |
rat |
| Tobias Bast, Marie Pezze, Stephanie McGarrit. Cognitive deficits caused by prefrontal cortical and hippocampal neural disinhibition. British journal of pharmacology. vol 174. issue 19. 2018-05-22. PMID:28477384. |
we consider conceptual implications of these findings, regarding the distinct relationships of distinct cognitive functions to prefrontal and hippocampal gaba tone and neural activity. |
2018-05-22 |
2023-08-13 |
rat |
| Mohammad Nasehi, Niyousha Alaghmandan-Motlagh, Mohaddeseh Ebrahimi-Ghiri, Mohammad Nami, Mohammad-Reza Zarrindas. The interaction between hippocampal GABA-B and cannabinoid receptors upon spatial change and object novelty discrimination memory function. Psychopharmacology. vol 234. issue 20. 2018-05-22. PMID:28779310. |
previous studies have postulated functional links between gaba and cannabinoid systems in the hippocampus. |
2018-05-22 |
2023-08-13 |
mouse |
| Mirjam Sibbe, Akos Kuli. GABAergic Regulation of Adult Hippocampal Neurogenesis. Molecular neurobiology. vol 54. issue 7. 2018-05-18. PMID:27599499. |
the roles of the inhibitory neurotransmitter γ-aminobutyric acid (gaba) in the proliferation and differentiation of stem cells and progenitor cells, as well as in the control of network activity of hippocampal stem cells, have been extensively investigated in recent decades. |
2018-05-18 |
2023-08-13 |
Not clear |
| Mirjam Sibbe, Akos Kuli. GABAergic Regulation of Adult Hippocampal Neurogenesis. Molecular neurobiology. vol 54. issue 7. 2018-05-18. PMID:27599499. |
this review highlights the general functions of gabaergic signalling and provides an exciting insight into the diverse functions of gaba in adult hippocampal stem cell biology. |
2018-05-18 |
2023-08-13 |
Not clear |
| Nadezhda A Dorofeeva, Yuliya S Grigorieva, Liubov S Nikitina, Elena A Lavrova, Elizaveta V Nasluzova, Margarita V Glazova, Elena V Chernigovskay. Effects of ERK1/2 kinases inactivation on the nigrostriatal system of Krushinsky-Molodkina rats genetically prone to audiogenic seizures. Neurological research. vol 39. issue 10. 2018-05-15. PMID:28738742. |
recently, we demonstrated that inhibition of erk1/2 activity by sl-327 treatment blocks seizure behavior in krushinsky-molodkina (km) rats, which was mediated by altering of gaba and glutamate release mechanism in the hippocampus. |
2018-05-15 |
2023-08-13 |
rat |
| Kentaro Tokudome, Takahiro Okumura, Saki Shimizu, Tomoji Mashimo, Akiko Takizawa, Tadao Serikawa, Ryo Terada, Shizuka Ishihara, Naofumi Kunisawa, Masashi Sasa, Yukihiro Ohn. Synaptic vesicle glycoprotein 2A (SV2A) regulates kindling epileptogenesis via GABAergic neurotransmission. Scientific reports. vol 6. 2018-05-02. PMID:27265781. |
neurochemical studies revealed that the sv2a(l174q) mutation specifically reduced depolarization-induced gaba, but not glutamate, release in the hippocampus without affecting basal release or the sv2a expression level in gabaergic neurons. |
2018-05-02 |
2023-08-13 |
rat |
| Jun-Ping Zhang, Ke-Ying Zhang, Ling Guo, Qi-Liang Chen, Peng Gao, Tian Wang, Jing Li, Guo-Zhen Guo, Gui-Rong Din. Effects of 1.8 GHz Radiofrequency Fields on the Emotional Behavior and Spatial Memory of Adolescent Mice. International journal of environmental research and public health. vol 14. issue 11. 2018-04-23. PMID:29113072. |
however, the anxiety-like behavior increased in mice, while, the levels of γ-aminobutyric acid (gaba) and aspartic acid (asp) in cortex and hippocampus significantly decreased after rf exposure. |
2018-04-23 |
2023-08-13 |
mouse |
| Guofeng Wu, Likun Wang, Zhen Hong, Siying Ren, Feng Zho. Hippocampal low-frequency stimulation inhibits afterdischarge and increases GABA (A) receptor expression in amygdala-kindled pharmacoresistant epileptic rats. Neurological research. vol 39. issue 8. 2018-04-17. PMID:28502217. |
hippocampal low-frequency stimulation inhibits afterdischarge and increases gaba (a) receptor expression in amygdala-kindled pharmacoresistant epileptic rats. |
2018-04-17 |
2023-08-13 |
rat |
| Guofeng Wu, Likun Wang, Zhen Hong, Siying Ren, Feng Zho. Hippocampal low-frequency stimulation inhibits afterdischarge and increases GABA (A) receptor expression in amygdala-kindled pharmacoresistant epileptic rats. Neurological research. vol 39. issue 8. 2018-04-17. PMID:28502217. |
the purpose of the present study was to observe the effects of hippocampal low-frequency stimulation (hip-lfs) on amygdala afterdischarge and gaba (a) receptor expression in pharmacoresistant epileptic (pre) rats. |
2018-04-17 |
2023-08-13 |
rat |
| Yukihiro Ohno, Kentaro Tokudom. Therapeutic Role of Synaptic Vesicle Glycoprotein 2A (SV2A) in Modulating Epileptogenesis. CNS & neurological disorders drug targets. vol 16. issue 4. 2018-04-16. PMID:28393712. |
although the functional mechanisms of sv2a in regulating epileptogenesis remain unknown, studies using animals carrying the sv2a missense mutation showed that the dysfunction of sv2a preferentially disrupts action potential-induced γ-aminiobutyric acid (gaba), but not glutamate, released in the limbic regions (i.e., hippocampus and amygdala) and markedly facilitates kindling epileptogenesis. |
2018-04-16 |
2023-08-13 |
mouse |
| Rachna Mehta, Sudhuman Singh, Mudasir Ahmad Khanday, Birendra Nath Mallic. Reciprocal changes in noradrenaline and GABA levels in discrete brain regions upon rapid eye movement sleep deprivation in rats. Neurochemistry international. vol 108. 2018-04-13. PMID:28427932. |
in this study using high performance liquid chromatography (hplc) we quantified noradrenaline (na) and gamma-amino butyric acid (gaba) levels in locus coeruleus (lc), dorsal raphe (dr), pedunculo-pontine tegmentum (ppt), frontal lobe (fl), cortex and hippocampus (hippo) in control and after 96 h rems deprivation (remsd) rats. |
2018-04-13 |
2023-08-13 |
rat |
| João A Amorim, Paula M Canas, Angelo R Tomé, Anabela P Rolo, Paula Agostinho, Carlos M Palmeira, Rodrigo A Cunh. Mitochondria in Excitatory and Inhibitory Synapses have Similar Susceptibility to Amyloid-β Peptides Modeling Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 60. issue 2. 2018-04-09. PMID:28869472. |
the direct exposure of hippocampal synaptosomes to aβ1-42 (500 nm) similarly decreased mitochondrial membrane potential (tmrm+ fluorescence) and increased mitochondria-derived oxygen radicals (mitotraker®red-cm-h2xros fluorescence) in individual glutamatergic (vesicular glutamate transporter-immunopositive) and gabaergic (vesicular gaba transporter-immunopositive) synaptosomes. |
2018-04-09 |
2023-08-13 |
rat |
| Li-Rong Shao, Carl E Stafstro. Glycolytic inhibition by 2-deoxy-d-glucose abolishes both neuronal and network bursts in an in vitro seizure model. Journal of neurophysiology. vol 118. issue 1. 2018-03-26. PMID:28404824. |
the effect of glycolytic inhibition on neuronal firing was tested in spontaneously active hippocampal neurons (ca3) when synaptic transmission was left intact or blocked with ampa, nmda, and gaba |
2018-03-26 |
2023-08-13 |
Not clear |
| Jinhong Jiang, Yali Peng, Zhen He, Lijuan Wei, Weidong Jin, Xiaoli Wang, Min Chan. Intrahippocampal injection of Cortistatin-14 impairs recognition memory consolidation in mice through activation of sst Brain research. vol 1666. 2018-03-13. PMID:28477863. |
in the hippocampus, cst-14 inhibits ca1 neuronal pyramidal cell firing and co-exists with gaba. |
2018-03-13 |
2023-08-13 |
mouse |
| Zhen Li, Zhuyan You, Min Li, Liang Pang, Juan Cheng, Liecheng Wan. Protective Effect of Resveratrol on the Brain in a Rat Model of Epilepsy. Neuroscience bulletin. vol 33. issue 3. 2018-03-09. PMID:28161868. |
during acute, silent and chronic phases of epilepsy, the expression of hippocampal kainate glutamate receptor (gluk2) and the gaba |
2018-03-09 |
2023-08-13 |
rat |
| Andrew Hooper, Patrick M Fuller, Jamie Maguir. Hippocampal corticotropin-releasing hormone neurons support recognition memory and modulate hippocampal excitability. PloS one. vol 13. issue 1. 2018-03-09. PMID:29346425. |
additional experiments are needed to reconcile the functions of gaba and crh signaling of hippocampal crh neurons on hippocampal function. |
2018-03-09 |
2023-08-13 |
mouse |
| Jin Qi, Minjung Kim, Russell Sanchez, Saba M Ziaee, Jhumku D Kohtz, Sookyong Ko. Enhanced susceptibility to stress and seizures in GAD65 deficient mice. PloS one. vol 13. issue 1. 2018-03-09. PMID:29377906. |
immunohistochemical characterization of interneuron subtypes in gad65-/- mice showed a selective decrease in gaba and neuropeptide y (npy) levels and no change in calbindin (clb) or calretinin (clr) immunoreactivity in the hippocampus. |
2018-03-09 |
2023-08-13 |
mouse |
| Junko Kono, Kohtarou Konno, Ashraf Hossain Talukder, Toshimitsu Fuse, Manabu Abe, Katsuya Uchida, Shuhei Horio, Kenji Sakimura, Masahiko Watanabe, Keiichi Ito. Distribution of corticotropin-releasing factor neurons in the mouse brain: a study using corticotropin-releasing factor-modified yellow fluorescent protein knock-in mouse. Brain structure & function. vol 222. issue 4. 2018-03-05. PMID:27638512. |
we demonstrated that the crf neurons contain glutamate in the pir and io, while they contain gamma-aminobutyric acid in the neocortex, the bed nucleus of the stria terminalis, the hippocampus, and the amygdala. |
2018-03-05 |
2023-08-13 |
mouse |
| Mohaddeseh Ebrahimi-Ghiri, Masoumeh Rostampour, Mehdi Jamshidi-Mehr, Mohammad Nasehi, Mohammad-Reza Zarrindas. Role of CA1 GABA Brain research. vol 1678. 2018-03-02. PMID:29038006. |
role of ca1 gaba to investigate the interaction between hippocampal γ-aminobutyric acid gaba |
2018-03-02 |
2023-08-13 |
Not clear |