| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R K Solanki, P Sharma, A Tyagi, C Sing. Serum Levels of Neuroactive Steroids in First-episode Antipsychotic-naïve Schizophrenic Patients and Its Correlation with Aggression: A Case-control Study. East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan. vol 27. issue 2. 2018-07-27. PMID:28652501. |
these neurosteroids in turn act on the hippocampus and interact with gamma-aminobutyric acid and n-methyl-d-aspartate receptors leading to neurotoxicity and may be involved in the neurobiology of aggression. |
2018-07-27 |
2023-08-13 |
Not clear |
| Vladimirs Pilipenko, Karina Narbute, Ulrika Beitnere, Juris Rumaks, Jolanta Pupure, Baiba Jansone, Vija Klus. Very low doses of muscimol and baclofen ameliorate cognitive deficits and regulate protein expression in the brain of a rat model of streptozocin-induced Alzheimer's disease. European journal of pharmacology. vol 818. 2018-07-27. PMID:29133125. |
in the present study, we used a non-transgenic rat model of ad obtained by intracerebroventricular streptozocin (stz) injection and assessed the effects of muscimol and baclofen at very low doses (0.01-0.05mg/kg) on spatial memory and the expression of cortical and hippocampal proteins related to neuroinflammation, namely proteins involved in astroglial functions (glial fibrillary acidic protein, gfap), gaba synthesis (gaba synthesizing enzyme, glutamic acid decarboxylase 67, gad67) and acetylcholine degradation (acetylcholine esterase). |
2018-07-27 |
2023-08-13 |
rat |
| Benoît Silvestre de Ferron, Catherine Vilpoux, Myriam Kervern, Alexandre Robert, Johan Antol, Mickael Naassila, Olivier Pierrefich. Increase of KCC2 in hippocampal synaptic plasticity disturbances after perinatal ethanol exposure. Addiction biology. vol 22. issue 6. 2018-07-16. PMID:27778437. |
we studied in rat hippocampus slice, the involvement of the chloride co-transporters nkcc1 and kcc2, in the role of gaba |
2018-07-16 |
2023-08-13 |
rat |
| N Kokras, N Pastromas, D Papasava, C de Bournonville, C A Cornil, C Dall. Sex differences in behavioral and neurochemical effects of gonadectomy and aromatase inhibition in rats. Psychoneuroendocrinology. vol 87. 2018-07-13. PMID:29054014. |
the hippocampus and prefrontal cortex (pfc) were analyzed for monoamine (noradrenaline, dopamine and serotonin), as well as amino acid (gaba, glutamate, glycine, taurine, alanine and histidine) levels. |
2018-07-13 |
2023-08-13 |
human |
| Silke Lissek, Anne Golisch, Benjamin Glaubitz, Martin Tegenthof. The GABAergic system in prefrontal cortex and hippocampus modulates context-related extinction learning and renewal in humans. Brain imaging and behavior. vol 11. issue 6. 2018-07-09. PMID:27928709. |
animal studies implicate hippocampal γ-aminobutyric acid (gaba) a receptors in extinction and renewal. |
2018-07-09 |
2023-08-13 |
human |
| Christopher B Ransom, Zucheng Ye, William J Spain, George B Richerso. Modulation of Tonic GABA Currents by Anion Channel and Connexin Hemichannel Antagonists. Neurochemical research. vol 42. issue 9. 2018-07-09. PMID:28401401. |
to investigate this, we measured the effects of anion channel/hemichannel antagonists on tonic gaba currents of rat hippocampal neurons. |
2018-07-09 |
2023-08-13 |
rat |
| Christopher B Ransom, Zucheng Ye, William J Spain, George B Richerso. Modulation of Tonic GABA Currents by Anion Channel and Connexin Hemichannel Antagonists. Neurochemical research. vol 42. issue 9. 2018-07-09. PMID:28401401. |
in contrast to predictions, blockade of anion channels and hemichannels with nppb potentiated tonic gaba currents of neurons in culture and acute hippocampal slices. |
2018-07-09 |
2023-08-13 |
rat |
| Giada Cellot, Laura Maggi, Maria Amalia Di Castro, Myriam Catalano, Rosanna Migliore, Michele Migliore, Maria Luisa Scattoni, Gemma Calamandrei, Enrico Cherubin. Premature changes in neuronal excitability account for hippocampal network impairment and autistic-like behavior in neonatal BTBR T+tf/J mice. Scientific reports. vol 6. 2018-07-03. PMID:27526668. |
coherent network oscillations (gdps), generated in the immature hippocampus by the synergistic action of gaba and glutamate, both depolarizing and excitatory, play a key role in the construction of neuronal circuits. |
2018-07-03 |
2023-08-13 |
mouse |
| Xin Wu, Mariappan Muthuchamy, Doodipala Samba Redd. Atomic force microscopy investigations of fibronectin and α5β1-integrin signaling in neuroplasticity and seizure susceptibility in experimental epilepsy. Epilepsy research. vol 138. 2018-06-28. PMID:29096132. |
in patch-clamp recordings, fibronectin significantly inhibited gaba current, while rgd, which is known to disrupt fibronectin-integrin-dependent cell adhesive events, strikingly enhanced gaba tonic currents in dggcs in hippocampal slices. |
2018-06-28 |
2023-08-13 |
mouse |
| Shahram Zarrabian, Mohammad Nasehi, Maryam Farrahizadeh, Mohammad-Reza Zarrindas. The role of CA3 GABA Progress in neuro-psychopharmacology & biological psychiatry. vol 79. issue Pt B. 2018-06-12. PMID:28800869. |
the role of ca3 gaba glutamatergic and gabaergic systems play key roles in the hippocampus and affect the pathogenesis of anxiety- and memory-related processes. |
2018-06-12 |
2023-08-13 |
Not clear |
| Natalia Pozdnyakov. Consequences of perinatal hypoxia in developing brain: Changes in GABA transporter functioning in cortical, hippocampal and thalamic rat nerve terminals. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 63. 2018-06-12. PMID:28888818. |
consequences of perinatal hypoxia in developing brain: changes in gaba transporter functioning in cortical, hippocampal and thalamic rat nerve terminals. |
2018-06-12 |
2023-08-13 |
rat |
| Ana C Pereira, Xiangling Mao, Caroline S Jiang, Guoxin Kang, Sara Milrad, Bruce S McEwen, Ana C Krieger, Dikoma C Shung. Dorsolateral prefrontal cortex GABA deficit in older adults with sleep-disordered breathing. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 38. 2018-06-08. PMID:28874569. |
levels of gaba and those of the combined resonances of glutamate and glutamine (glx), were measured by 1h mrs in the left dorsolateral prefrontal cortex (l-dlpfc) and bilateral hippocampal regions of 19 older adults (age ± sd: 66.1 ± 1.9 years) with moderate to severe sdb, defined as having an apnea-hypopnea index (ahi) greater than 15 as assessed by polysomnography, and in 14 older adults (age ± sd: 62.3 ± 1.3 years) without sdb (ahi < 5). |
2018-06-08 |
2023-08-13 |
human |
| Christine Winter, Dana M Greene, Paraskevi Mavrogiorgou, Helge Schaper, Reinhard Sohr, Abel Bult-Ito, Georg Jucke. Altered serotonergic and GABAergic neurotransmission in a mice model of obsessive-compulsive disorder. Behavioural brain research. vol 337. 2018-06-08. PMID:28916503. |
the neurochemical investigation of several brain regions of the corticostriato-thalamocortical circuity, i.e., nucleus caudatus (cpu), nucleus accumbens (nac), globus pallidus (gp), hippocampus (hpc), amygdala (am), ventral tegmental area (vta) and substantia nigra (sn) was performed by electrochemical (serotonin and dopamine) and fluorescence (glutamate and gaba) hplc detection. |
2018-06-08 |
2023-08-13 |
mouse |
| Bianca Brawek, Robert Chesters, Daniel Klement, Julia Müller, Chommanad Lerdkrai, Marina Hermes, Olga Garaschu. A bell-shaped dependence between amyloidosis and GABA accumulation in astrocytes in a mouse model of Alzheimer's disease. Neurobiology of aging. vol 61. 2018-06-04. PMID:29107186. |
moreover, hippocampal astrocytes upregulate their γ-aminobutyric acid (gaba) content and enhance tonic inhibition, likely causing local circuit imbalance. |
2018-06-04 |
2023-08-13 |
mouse |
| Nina Levar, Judith M C van Leeuwen, Damiaan Denys, Guido A van Winge. Divergent influences of anterior cingulate cortex GABA concentrations on the emotion circuitry. NeuroImage. vol 158. 2018-06-01. PMID:28669913. |
gaba levels were positively correlated with blood oxygen level dependent (bold) responses to emotional stimuli in the amygdala and to emotional and neutral stimuli in the hippocampus. |
2018-06-01 |
2023-08-13 |
human |
| Nina Levar, Judith M C van Leeuwen, Damiaan Denys, Guido A van Winge. Divergent influences of anterior cingulate cortex GABA concentrations on the emotion circuitry. NeuroImage. vol 158. 2018-06-01. PMID:28669913. |
our results suggest positive influences of dacc gaba on bold responses in the hippocampus and amygdala, and negative influences on bold responses in the dacc that are dependent on emotional valence. |
2018-06-01 |
2023-08-13 |
human |
| Alireza Mousavi Majd, Forough Ebrahim Tabar, Arghavan Afghani, Sahand Ashrafpour, Samaneh Dehghan, Mohammad Gol, Manouchehr Ashrafpour, Fereshteh Pourabdolhossei. Inhibition of GABA A receptor improved spatial memory impairment in the local model of demyelination in rat hippocampus. Behavioural brain research. vol 336. 2018-06-01. PMID:28866129. |
inhibition of gaba a receptor improved spatial memory impairment in the local model of demyelination in rat hippocampus. |
2018-06-01 |
2023-08-13 |
rat |
| Alireza Mousavi Majd, Forough Ebrahim Tabar, Arghavan Afghani, Sahand Ashrafpour, Samaneh Dehghan, Mohammad Gol, Manouchehr Ashrafpour, Fereshteh Pourabdolhossei. Inhibition of GABA A receptor improved spatial memory impairment in the local model of demyelination in rat hippocampus. Behavioural brain research. vol 336. 2018-06-01. PMID:28866129. |
here, we investigate the role of gaba a receptor on spatial memory in the local model of hippocampal demyelination. |
2018-06-01 |
2023-08-13 |
rat |
| Giampaolo Milior, Maria Amalia Di Castro, Livio Pepe' Sciarria, Stefano Garofalo, Igor Branchi, Davide Ragozzino, Cristina Limatola, Laura Magg. Electrophysiological Properties of CA1 Pyramidal Neurons along the Longitudinal Axis of the Mouse Hippocampus. Scientific reports. vol 6. 2018-05-29. PMID:27922053. |
these findings indicate an increased probability of both gaba and glutamate release and a reduced plasticity in the ventral compared to more dorsal regions of the hippocampus. |
2018-05-29 |
2023-08-13 |
mouse |
| Tobias Bast, Marie Pezze, Stephanie McGarrit. Cognitive deficits caused by prefrontal cortical and hippocampal neural disinhibition. British journal of pharmacology. vol 174. issue 19. 2018-05-22. PMID:28477384. |
we review recent evidence concerning the significance of inhibitory gaba transmission and of neural disinhibition, that is, deficient gaba transmission, within the prefrontal cortex and the hippocampus, for clinically relevant cognitive functions. |
2018-05-22 |
2023-08-13 |
rat |