| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T J Montine, T M Underhill, E Linney, D G Graha. Fibroblasts that express aromatic amino acid decarboxylase have increased sensitivity to the synergistic cytotoxicity of L-dopa and manganese. Toxicology and applied pharmacology. vol 128. issue 1. 1994-10-06. PMID:8079344. |
manganism, a neurodegenerative disease that can follow chronic exposure to mn, has been associated with lesions in the basal ganglia and depletion of dopamine and its metabolites in this brain region. |
1994-10-06 |
2023-08-12 |
cattle |
| M Bubse. 6-Hydroxydopamine lesions of the medial prefrontal cortex of rats do not affect dopamine metabolism in the basal ganglia at short and long postsurgical intervals. Neurochemical research. vol 19. issue 4. 1994-09-19. PMID:8065499. |
6-hydroxydopamine lesions of the medial prefrontal cortex of rats do not affect dopamine metabolism in the basal ganglia at short and long postsurgical intervals. |
1994-09-19 |
2023-08-12 |
rat |
| A J Stoess. Localization of striatal and nigral tachykinin receptors in the rat. Brain research. vol 646. issue 1. 1994-09-15. PMID:7519961. |
the effects of lesioning mesostriatal dopamine projections or striatal neurons on tachykinin binding in the basal ganglia were assessed in the rat. |
1994-09-15 |
2023-08-12 |
rat |
| M Gerlach, D Ben-Shachar, P Riederer, M B Youdi. Altered brain metabolism of iron as a cause of neurodegenerative diseases? Journal of neurochemistry. vol 63. issue 3. 1994-09-08. PMID:7519659. |
studies of iron distribution in the human brain have demonstrated that the degree of iron deposition, primarily in the basal ganglia (a predominantly dopamine structure), increases with age (hallgren and sourander, 1958) and in certain disorders, most notably the basal ganglia disorders (seitelberger, 1964). |
1994-09-08 |
2023-08-12 |
human |
| D G Cole, M Di Figli. Reserpine increases Fos activity in the rat basal ganglia via a quinpirole-sensitive mechanism. Neuroscience. vol 60. issue 1. 1994-09-08. PMID:7914358. |
because dopamine is believed to excite striatal neurons via d1 receptors and inhibit them via d2 receptors, we hypothesized that acute dopamine depletion would increase fos activity in basal ganglia circuits normally inhibited by dopaminergic input to d2 receptors. |
1994-09-08 |
2023-08-12 |
rat |
| D G Cole, M Di Figli. Reserpine increases Fos activity in the rat basal ganglia via a quinpirole-sensitive mechanism. Neuroscience. vol 60. issue 1. 1994-09-08. PMID:7914358. |
acute dopamine depletion, therefore, increases fos activity in the basal ganglia by disinhibiting d2 circuits. |
1994-09-08 |
2023-08-12 |
rat |
| Z H Qin, L W Zhou, B Weis. D2 dopamine receptor messenger RNA is altered to a greater extent by blockade of glutamate receptors than by blockade of dopamine receptors. Neuroscience. vol 60. issue 1. 1994-09-08. PMID:8052421. |
to study further the molecular mechanisms by which glutamate and dopamine interact to regulate the functions of the basal ganglia, the effects of persistently inhibiting dopamine receptors and glutamate n-methyl-d-aspartate receptors on the density of d1 and d2 dopamine receptors and on the level of their transcripts were examined in mouse brain. |
1994-09-08 |
2023-08-12 |
mouse |
| Z H Qin, L W Zhou, B Weis. D2 dopamine receptor messenger RNA is altered to a greater extent by blockade of glutamate receptors than by blockade of dopamine receptors. Neuroscience. vol 60. issue 1. 1994-09-08. PMID:8052421. |
these results suggest that n-methyl-d-aspartate receptors play an important role in the expression of d2 dopamine receptors in basal ganglia. |
1994-09-08 |
2023-08-12 |
mouse |
| N D Volkow, J S Fowler, G J Wang, J Logan, D Schlyer, R MacGregor, R Hitzemann, A P Wol. Decreased dopamine transporters with age in health human subjects. Annals of neurology. vol 36. issue 2. 1994-09-06. PMID:8053661. |
the ratio of the distribution volume for [11c]cocaine in basal ganglia to that in cerebellum was used as a model parameter for dopamine transporter availability and showed a significant negative correlation with age (r = 0.65, p < 0.0005). |
1994-09-06 |
2023-08-12 |
human |
| N L Potts, J R Davidson, K R Krishnan, P M Doraiswam. Magnetic resonance imaging in social phobia. Psychiatry research. vol 52. issue 1. 1994-08-30. PMID:8047620. |
recent studies have implicated dopamine and the basal ganglia circuits in the pathophysiology of social phobia. |
1994-08-30 |
2023-08-12 |
human |
| I Q Whishaw, B Gorny, L T Tran-Nguyen, E Castañeda, E I Miklyaeva, S M Pelli. Making two movements at once: impairments of movement, posture, and their integration underlie the adult skilled reaching deficit of neonatally dopamine-depleted rats. Behavioural brain research. vol 61. issue 1. 1994-08-16. PMID:8031497. |
the results are consistent with the hypotheses that the basal ganglia, including its dopamine innervation, is important for enabling voluntary movements and postural adjustments and perhaps also the simultaneous performance of two movements at the same time. |
1994-08-16 |
2023-08-12 |
rat |
| D G Standaert, C M Testa, A B Young, J B Penne. Organization of N-methyl-D-aspartate glutamate receptor gene expression in the basal ganglia of the rat. The Journal of comparative neurology. vol 343. issue 1. 1994-08-10. PMID:8027428. |
nmda ligand binding sites are abundant in the structures of the basal ganglia, and nmda receptors have been linked to neuronal excitability, neuropeptide gene expression, and regulation of dopamine release in these regions. |
1994-08-10 |
2023-08-12 |
rat |
| G Nikkhah, C Bentlage, M G Cunningham, A Björklun. Intranigral fetal dopamine grafts induce behavioral compensation in the rat Parkinson model. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 6. 1994-07-11. PMID:7911516. |
recent pharmacological and physiological data have provided strong evidence that dopamine released from dendrites of the substantia nigra pars compacta (snc) neurons within the pars reticulata (snr) plays an important role in the regulation of the basal ganglia output pathways. |
1994-07-11 |
2023-08-12 |
rat |
| O Shirakawa, C A Tamming. Basal ganglia GABAA and dopamine D1 binding site correlates of haloperidol-induced oral dyskinesias in rat. Experimental neurology. vol 127. issue 1. 1994-07-07. PMID:8200438. |
basal ganglia gabaa and dopamine d1 binding site correlates of haloperidol-induced oral dyskinesias in rat. |
1994-07-07 |
2023-08-12 |
rat |
| R K Schwarting, G Pei, S Söderström, T Ebendal, J P Husto. Unilateral stimulation or removal of rat vibrissae: analysis of nerve growth factor and tyrosine hydroxylase mRNA in the brain. Behavioural brain research. vol 60. issue 1. 1994-06-17. PMID:7910464. |
previous work has shown that unilateral manipulation of vibrissae in the rat can lead to behavioral asymmetries and to neuronal changes in the basal ganglia: in brief, vibrissae stimulation led to increases in neostriatal dopamine release, whereas unilateral removal of vibrissae led to asymmetries in striatal afferents and to bilateral changes in mesencephalic dopamine mechanisms which were related to the occurrence of behavioral asymmetries and the later recovery therefrom. |
1994-06-17 |
2023-08-12 |
rat |
| R K Schwarting, G Pei, S Söderström, T Ebendal, J P Husto. Unilateral stimulation or removal of rat vibrissae: analysis of nerve growth factor and tyrosine hydroxylase mRNA in the brain. Behavioural brain research. vol 60. issue 1. 1994-06-17. PMID:7910464. |
the results are discussed with respect to the interaction of vibrissae function with the basal ganglia, the neurotransmitter dopamine and mechanism of functional recovery. |
1994-06-17 |
2023-08-12 |
rat |
| H A Gelbard, C D Applegat. Persistent increases in dopamine D2 receptor mRNA expression in basal ganglia following kindling. Epilepsy research. vol 17. issue 1. 1994-06-03. PMID:8174522. |
persistent increases in dopamine d2 receptor mrna expression in basal ganglia following kindling. |
1994-06-03 |
2023-08-12 |
Not clear |
| H A Jinnah, B E Wojcik, M Hunt, N Narang, K Y Lee, M Goldstein, J K Wamsley, P J Langlais, T Friedman. Dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 3 Pt 1. 1994-04-07. PMID:7509865. |
these results indicate that hprt deficiency is associated with a relatively specific deficit in basal ganglia dopamine systems that emerges during the first 2 months of postnatal development. |
1994-04-07 |
2023-08-12 |
mouse |
| M A Meyer, M M Goodma. Intravenously administered dopamine transporter site radioligand is not significantly retained in mouse substantia nigra or other sites outside of basal ganglia. Annals of neurology. vol 35. issue 3. 1994-04-05. PMID:8122897. |
intravenously administered dopamine transporter site radioligand is not significantly retained in mouse substantia nigra or other sites outside of basal ganglia. |
1994-04-05 |
2023-08-12 |
mouse |
| M Amalric, G F Koo. Functionally selective neurochemical afferents and efferents of the mesocorticolimbic and nigrostriatal dopamine system. Progress in brain research. vol 99. 1994-03-21. PMID:8108549. |
in summary, evidence is presented that the mesocorticolimbic and nigrostriatal dopamine systems form functionally selective afferents to different parts of the basal ganglia and these inputs are paralleled by functionally selective outputs. |
1994-03-21 |
2023-08-12 |
Not clear |