| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Arnold, K Tatsch, W H Oertel, T Vogl, J Schwarz, E Kraft, C M Kirsc. Clinical progressive supranuclear palsy: differential diagnosis by IBZM-SPECT and MRI. Journal of neural transmission. Supplementum. vol 42. 1994-12-22. PMID:7964681. |
specific striatal dopamine d2 receptor binding in ibzm-spect, as calculated by a basal ganglia to frontal cortex ratio (bg/fc) was reduced in 5 patients, but normal in 3 patients. |
1994-12-22 |
2023-08-12 |
Not clear |
| E F Walke. Developmentally moderated expressions of the neuropathology underlying schizophrenia. Schizophrenia bulletin. vol 20. issue 3. 1994-12-20. PMID:7526447. |
specifically, it is suggested that the diathesis for schizophrenia involves a functional excess of dopamine activity in the basal ganglia that serves to disrupt these circuits. |
1994-12-20 |
2023-08-12 |
Not clear |
| J Kornhuber, M Welle. Neuroleptic malignant syndrome. Current opinion in neurology. vol 7. issue 4. 1994-12-20. PMID:7952245. |
the neurochemical key features in all these conditions are probably functional dopamine deficiency and ensuing hyperactivity of excitatory amino acid neurotransmission in the basal ganglia and hypothalamus. |
1994-12-20 |
2023-08-12 |
Not clear |
| C C Chiueh, S J Huang, D L Murph. Suppression of hydroxyl radical formation by MAO inhibitors: a novel possible neuroprotective mechanism in dopaminergic neurotoxicity. Journal of neural transmission. Supplementum. vol 41. 1994-11-23. PMID:7931226. |
thus, .oh generation evoked by mptp analogues may be due mainly to a burst increase in iron-catalyzed autoxidation of released dopamine in the basal ganglia where high levels of iron and oxygen are present. |
1994-11-23 |
2023-08-12 |
Not clear |
| L Shao, J Billings, N Pfeiffer, H F Kun. Concentration recovery for SPECT CNS dopamine-receptor studies for monkeys. Medical physics. vol 21. issue 5. 1994-10-28. PMID:7935203. |
a series of images were taken with different concentration ratios between the basal ganglia and the other brain compartments to simulate the dynamic imaging study of the dopamine d2 receptor in a monkey brain. |
1994-10-28 |
2023-08-12 |
monkey |
| B M Pedro, L S Pilowsky, D C Costa, D R Hemsley, P J Ell, N P Verhoeff, R W Kerwin, N S Gra. Stereotypy, schizophrenia and dopamine D2 receptor binding in the basal ganglia. Psychological medicine. vol 24. issue 2. 1994-10-13. PMID:8084937. |
stereotypy, schizophrenia and dopamine d2 receptor binding in the basal ganglia. |
1994-10-13 |
2023-08-12 |
human |
| T J Montine, T M Underhill, E Linney, D G Graha. Fibroblasts that express aromatic amino acid decarboxylase have increased sensitivity to the synergistic cytotoxicity of L-dopa and manganese. Toxicology and applied pharmacology. vol 128. issue 1. 1994-10-06. PMID:8079344. |
manganism, a neurodegenerative disease that can follow chronic exposure to mn, has been associated with lesions in the basal ganglia and depletion of dopamine and its metabolites in this brain region. |
1994-10-06 |
2023-08-12 |
cattle |
| M Bubse. 6-Hydroxydopamine lesions of the medial prefrontal cortex of rats do not affect dopamine metabolism in the basal ganglia at short and long postsurgical intervals. Neurochemical research. vol 19. issue 4. 1994-09-19. PMID:8065499. |
6-hydroxydopamine lesions of the medial prefrontal cortex of rats do not affect dopamine metabolism in the basal ganglia at short and long postsurgical intervals. |
1994-09-19 |
2023-08-12 |
rat |
| A J Stoess. Localization of striatal and nigral tachykinin receptors in the rat. Brain research. vol 646. issue 1. 1994-09-15. PMID:7519961. |
the effects of lesioning mesostriatal dopamine projections or striatal neurons on tachykinin binding in the basal ganglia were assessed in the rat. |
1994-09-15 |
2023-08-12 |
rat |
| M Gerlach, D Ben-Shachar, P Riederer, M B Youdi. Altered brain metabolism of iron as a cause of neurodegenerative diseases? Journal of neurochemistry. vol 63. issue 3. 1994-09-08. PMID:7519659. |
studies of iron distribution in the human brain have demonstrated that the degree of iron deposition, primarily in the basal ganglia (a predominantly dopamine structure), increases with age (hallgren and sourander, 1958) and in certain disorders, most notably the basal ganglia disorders (seitelberger, 1964). |
1994-09-08 |
2023-08-12 |
human |
| D G Cole, M Di Figli. Reserpine increases Fos activity in the rat basal ganglia via a quinpirole-sensitive mechanism. Neuroscience. vol 60. issue 1. 1994-09-08. PMID:7914358. |
because dopamine is believed to excite striatal neurons via d1 receptors and inhibit them via d2 receptors, we hypothesized that acute dopamine depletion would increase fos activity in basal ganglia circuits normally inhibited by dopaminergic input to d2 receptors. |
1994-09-08 |
2023-08-12 |
rat |
| D G Cole, M Di Figli. Reserpine increases Fos activity in the rat basal ganglia via a quinpirole-sensitive mechanism. Neuroscience. vol 60. issue 1. 1994-09-08. PMID:7914358. |
acute dopamine depletion, therefore, increases fos activity in the basal ganglia by disinhibiting d2 circuits. |
1994-09-08 |
2023-08-12 |
rat |
| Z H Qin, L W Zhou, B Weis. D2 dopamine receptor messenger RNA is altered to a greater extent by blockade of glutamate receptors than by blockade of dopamine receptors. Neuroscience. vol 60. issue 1. 1994-09-08. PMID:8052421. |
to study further the molecular mechanisms by which glutamate and dopamine interact to regulate the functions of the basal ganglia, the effects of persistently inhibiting dopamine receptors and glutamate n-methyl-d-aspartate receptors on the density of d1 and d2 dopamine receptors and on the level of their transcripts were examined in mouse brain. |
1994-09-08 |
2023-08-12 |
mouse |
| Z H Qin, L W Zhou, B Weis. D2 dopamine receptor messenger RNA is altered to a greater extent by blockade of glutamate receptors than by blockade of dopamine receptors. Neuroscience. vol 60. issue 1. 1994-09-08. PMID:8052421. |
these results suggest that n-methyl-d-aspartate receptors play an important role in the expression of d2 dopamine receptors in basal ganglia. |
1994-09-08 |
2023-08-12 |
mouse |
| N D Volkow, J S Fowler, G J Wang, J Logan, D Schlyer, R MacGregor, R Hitzemann, A P Wol. Decreased dopamine transporters with age in health human subjects. Annals of neurology. vol 36. issue 2. 1994-09-06. PMID:8053661. |
the ratio of the distribution volume for [11c]cocaine in basal ganglia to that in cerebellum was used as a model parameter for dopamine transporter availability and showed a significant negative correlation with age (r = 0.65, p < 0.0005). |
1994-09-06 |
2023-08-12 |
human |
| N L Potts, J R Davidson, K R Krishnan, P M Doraiswam. Magnetic resonance imaging in social phobia. Psychiatry research. vol 52. issue 1. 1994-08-30. PMID:8047620. |
recent studies have implicated dopamine and the basal ganglia circuits in the pathophysiology of social phobia. |
1994-08-30 |
2023-08-12 |
human |
| I Q Whishaw, B Gorny, L T Tran-Nguyen, E Castañeda, E I Miklyaeva, S M Pelli. Making two movements at once: impairments of movement, posture, and their integration underlie the adult skilled reaching deficit of neonatally dopamine-depleted rats. Behavioural brain research. vol 61. issue 1. 1994-08-16. PMID:8031497. |
the results are consistent with the hypotheses that the basal ganglia, including its dopamine innervation, is important for enabling voluntary movements and postural adjustments and perhaps also the simultaneous performance of two movements at the same time. |
1994-08-16 |
2023-08-12 |
rat |
| D G Standaert, C M Testa, A B Young, J B Penne. Organization of N-methyl-D-aspartate glutamate receptor gene expression in the basal ganglia of the rat. The Journal of comparative neurology. vol 343. issue 1. 1994-08-10. PMID:8027428. |
nmda ligand binding sites are abundant in the structures of the basal ganglia, and nmda receptors have been linked to neuronal excitability, neuropeptide gene expression, and regulation of dopamine release in these regions. |
1994-08-10 |
2023-08-12 |
rat |
| G Nikkhah, C Bentlage, M G Cunningham, A Björklun. Intranigral fetal dopamine grafts induce behavioral compensation in the rat Parkinson model. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 6. 1994-07-11. PMID:7911516. |
recent pharmacological and physiological data have provided strong evidence that dopamine released from dendrites of the substantia nigra pars compacta (snc) neurons within the pars reticulata (snr) plays an important role in the regulation of the basal ganglia output pathways. |
1994-07-11 |
2023-08-12 |
rat |
| O Shirakawa, C A Tamming. Basal ganglia GABAA and dopamine D1 binding site correlates of haloperidol-induced oral dyskinesias in rat. Experimental neurology. vol 127. issue 1. 1994-07-07. PMID:8200438. |
basal ganglia gabaa and dopamine d1 binding site correlates of haloperidol-induced oral dyskinesias in rat. |
1994-07-07 |
2023-08-12 |
rat |