Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
A Biegon, K Dillon, N D Volkow, R J Hitzemann, J S Fowler, A P Wol. Quantitative autoradiography of cocaine binding sites in human brain postmortem. Synapse (New York, N.Y.). vol 10. issue 2. 1992-06-18. PMID:1585256. |
these findings suggest that cocaine binds to dopamine uptake sites in the human basal ganglia postmortem but that it also interacts with other classes of binding sites, depending on the concentration and brain region examined. |
1992-06-18 |
2023-08-11 |
human |
L Farde, H Hal. Positron emission tomography--examination of chemical transmission in the living human brain. Development of radioligands. Arzneimittel-Forschung. vol 42. issue 2A. 1992-06-16. PMID:1316756. |
in conclusion, these ligands can be used to quantitatively examine dopamine receptors in the human basal ganglia in vivo. |
1992-06-16 |
2023-08-11 |
human |
J Schwarz, K Tatsch, T Vogl, C M Kirsch, C Trenkwalder, G Arnold, T Gasser, W H Oerte. Marked reduction of striatal dopamine D2 receptors as detected by 123IBZM-SPECT in a Wilson's disease patient with generalized dystonia. Movement disorders : official journal of the Movement Disorder Society. vol 7. issue 1. 1992-05-04. PMID:1532631. |
ibzm is a dopamine d2 receptor antagonist with high affinity and specific binding to basal ganglia detectable by spect. |
1992-05-04 |
2023-08-11 |
Not clear |
L W Toled. The postanesthesia patient with Parkinson's disease. Journal of post anesthesia nursing. vol 7. issue 1. 1992-03-12. PMID:1531238. |
concentrations of dopamine and acetylcholine, neurotransmitters in the substantia nigra of the basal ganglia, become imbalanced. |
1992-03-12 |
2023-08-11 |
Not clear |
M S Aldrich, Z Hollingsworth, J B Penne. Dopamine-receptor autoradiography of human narcoleptic brain. Neurology. vol 42. issue 2. 1992-03-12. PMID:1736175. |
we used quantitative autoradiography to assess dopamine d1- and d2-receptor binding in basal ganglia and amygdala of five narcoleptic and 17 control human brains. |
1992-03-12 |
2023-08-11 |
human |
J Logan, S L Dewey, A P Wolf, J S Fowler, J D Brodie, B Angrist, N D Volkow, S J Gatle. Effects of endogenous dopamine on measures of [18F]N-methylspiroperidol binding in the basal ganglia: comparison of simulations and experimental results from PET studies in baboons. Synapse (New York, N.Y.). vol 9. issue 3. 1992-03-05. PMID:1685599. |
effects of endogenous dopamine on measures of [18f]n-methylspiroperidol binding in the basal ganglia: comparison of simulations and experimental results from pet studies in baboons. |
1992-03-05 |
2023-08-11 |
human |
E C Lauterbac. Serotonin reuptake inhibitors, paranoia, and the ventral basal ganglia. Clinical neuropharmacology. vol 14. issue 6. 1992-03-02. PMID:1837756. |
although the pharmacology and neurobiology of paranoia remain cryptic, several mechanisms, including 5ht3 receptor-mediated dopamine release, beta-noradrenergic receptor downregulation, or gabab receptor upregulation acting in the vicinity of the ventral basal ganglia (possibly in lateral orbitofrontal or anterior cingulate circuits), might apply to this phenomenon. |
1992-03-02 |
2023-08-11 |
Not clear |
O Hikosak. Dopamine and basal ganglia. The Japanese journal of psychiatry and neurology. vol 45. issue 2. 1992-02-13. PMID:1762258. |
dopamine and basal ganglia. |
1992-02-13 |
2023-08-11 |
Not clear |
M A Nastuk, A M Graybie. Pharmacologically defined M1 and M2 muscarinic cholinergic binding sites in the cat's substantia nigra: development and maturity. Brain research. Developmental brain research. vol 61. issue 1. 1991-11-04. PMID:1914150. |
these findings provide further evidence that the substantia nigra is a site of cholinergic transmission and suggest that the functional balance between acetylcholine and dopamine in the basal ganglia acts here as well as in the striatum. |
1991-11-04 |
2023-08-11 |
cat |
P A Rao, P B Molinoff, J N Joyc. Ontogeny of dopamine D1 and D2 receptor subtypes in rat basal ganglia: a quantitative autoradiographic study. Brain research. Developmental brain research. vol 60. issue 2. 1991-10-21. PMID:1832594. |
ontogeny of dopamine d1 and d2 receptor subtypes in rat basal ganglia: a quantitative autoradiographic study. |
1991-10-21 |
2023-08-11 |
rat |
P A Rao, P B Molinoff, J N Joyc. Ontogeny of dopamine D1 and D2 receptor subtypes in rat basal ganglia: a quantitative autoradiographic study. Brain research. Developmental brain research. vol 60. issue 2. 1991-10-21. PMID:1832594. |
the ontogeny of d1 and d2 dopamine (da) receptors in rat basal ganglia was examined by quantitative autoradiography using the iodinated ligands [125i]sch 23982 and [125i]iodobenzamide [( 125i]ibzm), respectively. |
1991-10-21 |
2023-08-11 |
rat |
K Fuxe, S O Ogre. The unique effect of remoxipride on dopamine utilization in the basal ganglia. Acta physiologica Scandinavica. vol 141. issue 4. 1991-09-20. PMID:1678908. |
the unique effect of remoxipride on dopamine utilization in the basal ganglia. |
1991-09-20 |
2023-08-11 |
Not clear |
J J Soghomonian, M F Chessele. Lesions of the dopaminergic nigrostriatal pathway alter preprosomatostatin messenger RNA levels in the striatum, the entopeduncular nucleus and the lateral hypothalamus of the rat. Neuroscience. vol 42. issue 1. 1991-08-30. PMID:1677745. |
the results suggest that dopamine exerts opposite effects on somatostatin gene expression in neurons of the striatum and the entopeduncular nucleus/lateral hypothalamus, effects which are likely to be of importance for the control of basal ganglia output activity. |
1991-08-30 |
2023-08-11 |
rat |
S P Siva. Dopamine dependent decrease in enkephalin and substance P levels in basal ganglia regions of postmortem parkinsonian brains. Neuropeptides. vol 18. issue 4. 1991-07-19. PMID:1711165. |
dopamine dependent decrease in enkephalin and substance p levels in basal ganglia regions of postmortem parkinsonian brains. |
1991-07-19 |
2023-08-11 |
Not clear |
S P Siva. Dopamine dependent decrease in enkephalin and substance P levels in basal ganglia regions of postmortem parkinsonian brains. Neuropeptides. vol 18. issue 4. 1991-07-19. PMID:1711165. |
this study examined whether a relationship exists between the degree of dopamine (da) loss and the changes in opioid (met5-enkephalin, me; dynorphin a (1-8) (dyn)) or tachykinin (substance p, sp) peptidergic systems in basal ganglia (caudate and putamen) and limbic (frontal cortex) regions of postmortem tissue samples derived from patients who died of parkinson's disease (pd). |
1991-07-19 |
2023-08-11 |
Not clear |
J N Joyce, A Janowsky, K A Nev. Characterization and distribution of [125I]epidepride binding to dopamine D2 receptors in basal ganglia and cortex of human brain. The Journal of pharmacology and experimental therapeutics. vol 257. issue 3. 1991-07-12. PMID:1828505. |
characterization and distribution of [125i]epidepride binding to dopamine d2 receptors in basal ganglia and cortex of human brain. |
1991-07-12 |
2023-08-11 |
human |
S P Sivam, J E Kraus. The adaptation of enkephalin, tachykinin and monoamine neurons of the basal ganglia following neonatal dopaminergic denervation is dependent on the extent of dopamine depletion. Brain research. vol 536. issue 1-2. 1991-05-21. PMID:1707718. |
the adaptation of enkephalin, tachykinin and monoamine neurons of the basal ganglia following neonatal dopaminergic denervation is dependent on the extent of dopamine depletion. |
1991-05-21 |
2023-08-11 |
rat |
B Sczesni, J Schröder, H Becker, H Przunte. [Neuroleptic malignant syndrome]. Wiener klinische Wochenschrift. vol 103. issue 1. 1991-05-15. PMID:1673041. |
the neuroleptic malignant syndrome (nms) is presumably caused by neuroleptic blockade of dopamine receptors, mainly in the basal ganglia and hypothalamus. |
1991-05-15 |
2023-08-11 |
Not clear |
K L Drew, W T O'Connor, J Kehr, U Ungersted. Regional specific effects of clozapine and haloperidol on GABA and dopamine release in rat basal ganglia. European journal of pharmacology. vol 187. issue 3. 1991-04-15. PMID:2073921. |
regional specific effects of clozapine and haloperidol on gaba and dopamine release in rat basal ganglia. |
1991-04-15 |
2023-08-11 |
rat |
K L Drew, W T O'Connor, J Kehr, U Ungersted. Regional specific effects of clozapine and haloperidol on GABA and dopamine release in rat basal ganglia. European journal of pharmacology. vol 187. issue 3. 1991-04-15. PMID:2073921. |
these data suggest that (1) regional differences in the effects of haloperidol and clozapine on gaba release in the basal ganglia may parallel the unique clinical profiles of these drugs; and (2) increases in dopamine release may occur independently of a gabaergic component in the dorsolateral striatum following low doses of haloperidol and clozapine and in the fundus striati following all effective doses of haloperidol. |
1991-04-15 |
2023-08-11 |
rat |