Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
E C Lauterbac. Serotonin reuptake inhibitors, paranoia, and the ventral basal ganglia. Clinical neuropharmacology. vol 14. issue 6. 1992-03-02. PMID:1837756. |
although the pharmacology and neurobiology of paranoia remain cryptic, several mechanisms, including 5ht3 receptor-mediated dopamine release, beta-noradrenergic receptor downregulation, or gabab receptor upregulation acting in the vicinity of the ventral basal ganglia (possibly in lateral orbitofrontal or anterior cingulate circuits), might apply to this phenomenon. |
1992-03-02 |
2023-08-11 |
Not clear |
O Hikosak. Dopamine and basal ganglia. The Japanese journal of psychiatry and neurology. vol 45. issue 2. 1992-02-13. PMID:1762258. |
dopamine and basal ganglia. |
1992-02-13 |
2023-08-11 |
Not clear |
M A Nastuk, A M Graybie. Pharmacologically defined M1 and M2 muscarinic cholinergic binding sites in the cat's substantia nigra: development and maturity. Brain research. Developmental brain research. vol 61. issue 1. 1991-11-04. PMID:1914150. |
these findings provide further evidence that the substantia nigra is a site of cholinergic transmission and suggest that the functional balance between acetylcholine and dopamine in the basal ganglia acts here as well as in the striatum. |
1991-11-04 |
2023-08-11 |
cat |
P A Rao, P B Molinoff, J N Joyc. Ontogeny of dopamine D1 and D2 receptor subtypes in rat basal ganglia: a quantitative autoradiographic study. Brain research. Developmental brain research. vol 60. issue 2. 1991-10-21. PMID:1832594. |
ontogeny of dopamine d1 and d2 receptor subtypes in rat basal ganglia: a quantitative autoradiographic study. |
1991-10-21 |
2023-08-11 |
rat |
P A Rao, P B Molinoff, J N Joyc. Ontogeny of dopamine D1 and D2 receptor subtypes in rat basal ganglia: a quantitative autoradiographic study. Brain research. Developmental brain research. vol 60. issue 2. 1991-10-21. PMID:1832594. |
the ontogeny of d1 and d2 dopamine (da) receptors in rat basal ganglia was examined by quantitative autoradiography using the iodinated ligands [125i]sch 23982 and [125i]iodobenzamide [( 125i]ibzm), respectively. |
1991-10-21 |
2023-08-11 |
rat |
K Fuxe, S O Ogre. The unique effect of remoxipride on dopamine utilization in the basal ganglia. Acta physiologica Scandinavica. vol 141. issue 4. 1991-09-20. PMID:1678908. |
the unique effect of remoxipride on dopamine utilization in the basal ganglia. |
1991-09-20 |
2023-08-11 |
Not clear |
J J Soghomonian, M F Chessele. Lesions of the dopaminergic nigrostriatal pathway alter preprosomatostatin messenger RNA levels in the striatum, the entopeduncular nucleus and the lateral hypothalamus of the rat. Neuroscience. vol 42. issue 1. 1991-08-30. PMID:1677745. |
the results suggest that dopamine exerts opposite effects on somatostatin gene expression in neurons of the striatum and the entopeduncular nucleus/lateral hypothalamus, effects which are likely to be of importance for the control of basal ganglia output activity. |
1991-08-30 |
2023-08-11 |
rat |
S P Siva. Dopamine dependent decrease in enkephalin and substance P levels in basal ganglia regions of postmortem parkinsonian brains. Neuropeptides. vol 18. issue 4. 1991-07-19. PMID:1711165. |
dopamine dependent decrease in enkephalin and substance p levels in basal ganglia regions of postmortem parkinsonian brains. |
1991-07-19 |
2023-08-11 |
Not clear |
S P Siva. Dopamine dependent decrease in enkephalin and substance P levels in basal ganglia regions of postmortem parkinsonian brains. Neuropeptides. vol 18. issue 4. 1991-07-19. PMID:1711165. |
this study examined whether a relationship exists between the degree of dopamine (da) loss and the changes in opioid (met5-enkephalin, me; dynorphin a (1-8) (dyn)) or tachykinin (substance p, sp) peptidergic systems in basal ganglia (caudate and putamen) and limbic (frontal cortex) regions of postmortem tissue samples derived from patients who died of parkinson's disease (pd). |
1991-07-19 |
2023-08-11 |
Not clear |
J N Joyce, A Janowsky, K A Nev. Characterization and distribution of [125I]epidepride binding to dopamine D2 receptors in basal ganglia and cortex of human brain. The Journal of pharmacology and experimental therapeutics. vol 257. issue 3. 1991-07-12. PMID:1828505. |
characterization and distribution of [125i]epidepride binding to dopamine d2 receptors in basal ganglia and cortex of human brain. |
1991-07-12 |
2023-08-11 |
human |
S P Sivam, J E Kraus. The adaptation of enkephalin, tachykinin and monoamine neurons of the basal ganglia following neonatal dopaminergic denervation is dependent on the extent of dopamine depletion. Brain research. vol 536. issue 1-2. 1991-05-21. PMID:1707718. |
the adaptation of enkephalin, tachykinin and monoamine neurons of the basal ganglia following neonatal dopaminergic denervation is dependent on the extent of dopamine depletion. |
1991-05-21 |
2023-08-11 |
rat |
B Sczesni, J Schröder, H Becker, H Przunte. [Neuroleptic malignant syndrome]. Wiener klinische Wochenschrift. vol 103. issue 1. 1991-05-15. PMID:1673041. |
the neuroleptic malignant syndrome (nms) is presumably caused by neuroleptic blockade of dopamine receptors, mainly in the basal ganglia and hypothalamus. |
1991-05-15 |
2023-08-11 |
Not clear |
K L Drew, W T O'Connor, J Kehr, U Ungersted. Regional specific effects of clozapine and haloperidol on GABA and dopamine release in rat basal ganglia. European journal of pharmacology. vol 187. issue 3. 1991-04-15. PMID:2073921. |
regional specific effects of clozapine and haloperidol on gaba and dopamine release in rat basal ganglia. |
1991-04-15 |
2023-08-11 |
rat |
K L Drew, W T O'Connor, J Kehr, U Ungersted. Regional specific effects of clozapine and haloperidol on GABA and dopamine release in rat basal ganglia. European journal of pharmacology. vol 187. issue 3. 1991-04-15. PMID:2073921. |
these data suggest that (1) regional differences in the effects of haloperidol and clozapine on gaba release in the basal ganglia may parallel the unique clinical profiles of these drugs; and (2) increases in dopamine release may occur independently of a gabaergic component in the dorsolateral striatum following low doses of haloperidol and clozapine and in the fundus striati following all effective doses of haloperidol. |
1991-04-15 |
2023-08-11 |
rat |
C Singer, J Sanchez-Ramos, W J Weine. Levodopa-responsive parkinsonism in a patient with Down's syndrome. European neurology. vol 30. issue 5. 1991-02-19. PMID:2148520. |
we discuss basal ganglia and dopamine abnormalities in ds and suggest that ds may be associated with parkinsonism. |
1991-02-19 |
2023-08-11 |
Not clear |
S Kaakkola, H Teräväine. Animal models of parkinsonism. Pharmacology & toxicology. vol 67. issue 2. 1991-01-24. PMID:2123984. |
the discovery of profound dopamine depletion of basal ganglia in patients with parkinson's disease and the development of antiparkinsonian drug therapy were largely based on animal models. |
1991-01-24 |
2023-08-11 |
mouse |
J M Trugman, C J Pronsky, G F Woote. Basal ganglia dopamine depletion does not alter D1 dopamine receptor binding properties. Advances in neurology. vol 53. 1990-12-13. PMID:2146858. |
basal ganglia dopamine depletion does not alter d1 dopamine receptor binding properties. |
1990-12-13 |
2023-08-11 |
Not clear |
B Berger, A Febvret, P Greengard, P S Goldman-Raki. DARPP-32, a phosphoprotein enriched in dopaminoceptive neurons bearing dopamine D1 receptors: distribution in the cerebral cortex of the newborn and adult rhesus monkey. The Journal of comparative neurology. vol 299. issue 3. 1990-12-06. PMID:2229482. |
darpp-32, a dopamine (da) and camp-regulated phosphoprotein, is associated with dopaminoceptive neurons bearing d-1 receptors in the basal ganglia. |
1990-12-06 |
2023-08-11 |
monkey |
B G Weick, T M Engber, Z Susel, T N Chase, J R Walter. Responses of substantia nigra pars reticulata neurons to GABA and SKF 38393 in 6-hydroxydopamine-lesioned rats are differentially affected by continuous and intermittent levodopa administration. Brain research. vol 523. issue 1. 1990-11-19. PMID:2119854. |
these results suggest that large variations in circulating levodopa levels in 6-hydroxydopamine lesioned rats may desensitize the behavioral responses to d1 dopamine agonist administration by down-regulating d1 and gaba receptor-mediated mechanisms of basal ganglia output through the substantia nigra pars reticulata. |
1990-11-19 |
2023-08-11 |
rat |
C Halldin, L Farde, T Högberg, H Hall, G Sedval. Carbon-11 labelling of eticlopride in two different positions--a selective high-affinity ligand for the study of dopamine D-2 receptors using PET. International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes. vol 41. issue 7. 1990-11-13. PMID:2170298. |
there was a marked accumulation of radioactivity in the basal ganglia, regions known to have a high density of dopamine d-2 receptors. |
1990-11-13 |
2023-08-11 |
monkey |