| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Hata, T Kita, Y Kamanaka, S Honda, K Kakehi, A Kawabata, E Ito. Catecholamine levels in the brain of SART (repeated cold)-stressed rats. Journal of autonomic pharmacology. vol 7. issue 3. 1988-03-07. PMID:3429462. |
5 cold-stressed rats showed increased noradrenaline levels only in the basal ganglia and dopamine levels in the hippocampus. |
1988-03-07 |
2023-08-11 |
rat |
| P J McKenn. Pathology, phenomenology and the dopamine hypothesis of schizophrenia. The British journal of psychiatry : the journal of mental science. vol 151. 1988-03-04. PMID:3322465. |
the basal ganglia, ventral striatum, septo-hippocampal system, and prefrontal cortex, sites of mesotelencephalic dopamine innervation, are examined and it is argued that their dysfunction could form the basis of particular schizophrenic symptom classes. |
1988-03-04 |
2023-08-11 |
Not clear |
| M J Bannon, P J Elliott, E B Bunne. Striatal tachykinin biosynthesis: regulation of mRNA and peptide levels by dopamine agonists and antagonists. Brain research. vol 427. issue 1. 1988-03-02. PMID:2448008. |
the effects of dopamine agonists and antagonists on rat basal ganglia substance p, substance k, and preprotachykinin mrna were examined. |
1988-03-02 |
2023-08-11 |
rat |
| C A Bloxham, D J Dick, M Moor. Reaction times and attention in Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry. vol 50. issue 9. 1987-12-14. PMID:3668566. |
animal studies have suggested that dopamine deficiency results in an increase in neural "noise" in the basal ganglia. |
1987-12-14 |
2023-08-11 |
human |
| E K Richfield, A B Young, J B Penne. Comparative distribution of dopamine D-1 and D-2 receptors in the basal ganglia of turtles, pigeons, rats, cats, and monkeys. The Journal of comparative neurology. vol 262. issue 3. 1987-11-05. PMID:2958517. |
a common feature of dopamine receptors in the basal ganglia is their heterogeneity in distribution and density. |
1987-11-05 |
2023-08-11 |
rat |
| E K Richfield, A B Young, J B Penne. Comparative distribution of dopamine D-1 and D-2 receptors in the basal ganglia of turtles, pigeons, rats, cats, and monkeys. The Journal of comparative neurology. vol 262. issue 3. 1987-11-05. PMID:2958517. |
the heterogeneity of dopamine receptors has similarities to and differences from the distribution of presynaptic dopamine and other neurotransmitter markers of the basal ganglia. |
1987-11-05 |
2023-08-11 |
rat |
| J M Gibson, R Pimlott, C Kennar. Ocular motor and manual tracking in Parkinson's disease and the effect of treatment. Journal of neurology, neurosurgery, and psychiatry. vol 50. issue 7. 1987-10-22. PMID:3625208. |
it is postulated that the ocular motor changes seen in parkinson's disease are contingent upon functional dopamine levels in the basal ganglia. |
1987-10-22 |
2023-08-11 |
human |
| J M Trugman, G F Woote. Selective D1 and D2 dopamine agonists differentially alter basal ganglia glucose utilization in rats with unilateral 6-hydroxydopamine substantia nigra lesions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 7. issue 9. 1987-10-21. PMID:3114439. |
selective d1 and d2 dopamine agonists differentially alter basal ganglia glucose utilization in rats with unilateral 6-hydroxydopamine substantia nigra lesions. |
1987-10-21 |
2023-08-11 |
rat |
| S P Sivam, P M Hudson, H A Tilson, J S Hon. GABA and dopamine interaction in the basal ganglia: dopaminergic supersensitivity following chronic elevation of brain gamma-aminobutyric acid levels. Brain research. vol 412. issue 1. 1987-09-11. PMID:3607459. |
gaba and dopamine interaction in the basal ganglia: dopaminergic supersensitivity following chronic elevation of brain gamma-aminobutyric acid levels. |
1987-09-11 |
2023-08-11 |
rat |
| A Kuruvilla, R Cherian, D Theodore, J Abraha. Changes in the content of dopamine and its metabolites in the basal ganglia following right middle cerebral artery occlusion and reflow in monkeys. Clinical and experimental pharmacology & physiology. vol 14. issue 1. 1987-08-28. PMID:3608238. |
changes in the content of dopamine and its metabolites in the basal ganglia following right middle cerebral artery occlusion and reflow in monkeys. |
1987-08-28 |
2023-08-11 |
monkey |
| A Kuruvilla, R Cherian, D Theodore, J Abraha. Changes in the content of dopamine and its metabolites in the basal ganglia following right middle cerebral artery occlusion and reflow in monkeys. Clinical and experimental pharmacology & physiology. vol 14. issue 1. 1987-08-28. PMID:3608238. |
there was a lowering of the dopamine (da) content of basal ganglia after 4 and 12 h of occlusion. |
1987-08-28 |
2023-08-11 |
monkey |
| D G Morgan, J O Marcusson, P Nyberg, P Wester, B Winblad, M N Gordon, C E Finc. Divergent changes in D-1 and D-2 dopamine binding sites in human brain during aging. Neurobiology of aging. vol 8. issue 3. 1987-08-10. PMID:3600950. |
these divergent changes in dopamine receptor subtypes with age result in an altered complement of dopamine receptors in older humans and may provide a basis for selective pharmacotherapy in disorders of the basal ganglia. |
1987-08-10 |
2023-08-11 |
human |
| J R Walters, D A Bergstrom, J H Carlson, T N Chase, A R Brau. D1 dopamine receptor activation required for postsynaptic expression of D2 agonist effects. Science (New York, N.Y.). vol 236. issue 4802. 1987-06-05. PMID:2953072. |
d1 and d2 dopamine receptors exert synergistic effects on the firing rates of basal ganglia neurons and on the expression of stereotyped behavior in rats. |
1987-06-05 |
2023-08-11 |
rat |
| J R Walters, D A Bergstrom, J H Carlson, T N Chase, A R Brau. D1 dopamine receptor activation required for postsynaptic expression of D2 agonist effects. Science (New York, N.Y.). vol 236. issue 4802. 1987-06-05. PMID:2953072. |
moreover, the ability of d2 agonists to induce changes in basal ganglia single unit activity and spontaneous motor activity is dependent upon the presence of endogenous dopamine to stimulate d1 receptors; in rats treated with alpha-methyl-rho-tyrosine to reduce endogenous dopamine levels, the neurophysiological and behavioral effects of the d2 agonist quinpirole are significantly attenuated, while the effects of nonselective agonists like apomorphine, which stimulate both d1 and d2 receptors, or combinations of a d2 agonist and a d1 agonist are not attenuated. |
1987-06-05 |
2023-08-11 |
rat |
| J R Walters, D A Bergstrom, J H Carlson, T N Chase, A R Brau. D1 dopamine receptor activation required for postsynaptic expression of D2 agonist effects. Science (New York, N.Y.). vol 236. issue 4802. 1987-06-05. PMID:2953072. |
thus, the previously held view that d2 receptors alone are responsible for evoking the changes in behavior and basal ganglia output induced by nonselective dopamine agonists and endogenous dopamine is not supported by these results, which indicate that these phenomena require concurrent stimulation of both dopamine receptor subtypes. |
1987-06-05 |
2023-08-11 |
rat |
| A Campbell, R J Baldessarini, N S Kula, V J Ram, J L Neumeye. S(+)methylenedioxy-N-n-propylnoraporphine: an orally active inhibitor of dopamine selective for rat limbic system. Brain research. vol 403. issue 2. 1987-05-20. PMID:3828830. |
the 10-11-methylenedioxy (mdo) derivative of s(+)n-n-propylnorapomorphine (npa) was prepared and tested as a possible active prodrug to s(+)npa, which we have recently found to exert in vivo activity suggestive of selective antagonism of dopamine receptors in the limbic forebrain but not the extrapyramidal basal ganglia. |
1987-05-20 |
2023-08-11 |
rat |
| E K Richfield, D L Debowey, J B Penney, A B Youn. Basal ganglia and cerebral cortical distribution of dopamine D1- and D2-receptors in neonatal and adult cat brain. Neuroscience letters. vol 73. issue 3. 1987-04-29. PMID:2951618. |
basal ganglia and cerebral cortical distribution of dopamine d1- and d2-receptors in neonatal and adult cat brain. |
1987-04-29 |
2023-08-11 |
cat |
| H S Bracha, C Shults, S D Glick, J E Kleinma. Spontaneous asymmetric circling behavior in hemi-parkinsonism; a human equivalent of the lesioned-circling rodent behavior. Life sciences. vol 40. issue 11. 1987-04-22. PMID:3821375. |
when induced experimentally in rodents, hemispheric asymmetry in basal ganglia dopamine results in spontaneous asymmetric circling toward the hemisphere with the lower level of dopamine. |
1987-04-22 |
2023-08-11 |
human |
| J P Bennett, M B Ferrari, C J Cru. GABA-mimetic drugs enhance apomorphine-induced contralateral turning in rats with unilateral nigrostriatal dopamine denervation: implications for the therapy of Parkinson's disease. Annals of neurology. vol 21. issue 1. 1987-04-15. PMID:3827213. |
postmortem brain studies indicate that patients with parkinson's disease have decreased basal ganglia gamma-aminobutyric acid (gaba) function in addition to profound striatal dopamine (da) deficiencies. |
1987-04-15 |
2023-08-11 |
rat |
| J H Carlson, D A Bergstrom, J R Walter. Stimulation of both D1 and D2 dopamine receptors appears necessary for full expression of postsynaptic effects of dopamine agonists: a neurophysiological study. Brain research. vol 400. issue 2. 1987-04-02. PMID:2880637. |
these results suggest that concurrent d1 and d2 receptor stimulation may be necessary for the full expression of postsynaptic receptor-mediated effects of dopamine and dopamine agonists in the basal ganglia. |
1987-04-02 |
2023-08-11 |
Not clear |