| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D B Calne, J K Kebabia. Parkinson's disease: unanswered questions. Journal of neural transmission. Supplementum. issue 16. 1981-01-16. PMID:6933216. |
the role of the depletion of dopamine in parkinsonism is also unclear; we do not even know whether the impact of the deficit is more significant in the basal ganglia, or the substantia nigra. |
1981-01-16 |
2023-08-12 |
Not clear |
| Tardive dyskinesia: summary of a Task Force Report of the American Psychiatric Association. By the Task Force on Late Neurological Effects of Antipsychotic Drugs. The American journal of psychiatry. vol 137. issue 10. 1980-11-24. PMID:6106389. |
the casue is unknown, but increased sensitivity to dopamine in the basal ganglia may contribute to the pathophysiology. |
1980-11-24 |
2023-08-12 |
Not clear |
| R H Roth, N G Bacopoulos, G Bustos, D E Redmon. Antipsychotic drugs: differential effects on dopamine neurons in basal ganglia and mesocortex following chronic administration in human and nonhuman primates. Advances in biochemical psychopharmacology. vol 24. 1980-10-27. PMID:6105797. |
antipsychotic drugs: differential effects on dopamine neurons in basal ganglia and mesocortex following chronic administration in human and nonhuman primates. |
1980-10-27 |
2023-08-12 |
human |
| E D Bir. Chemical pathology of Huntington's disease. Annual review of pharmacology and toxicology. vol 20. 1980-08-28. PMID:6446256. |
there are decreased concentrations of the neuroinhibitory transmitter gamma aminobutyric acid and this is associated with increased concentrations of dopamine and serotonin in the basal ganglia. |
1980-08-28 |
2023-08-12 |
Not clear |
| T Ashizawa, B M Patten, J Jankovi. Meige's syndrome. Southern medical journal. vol 73. issue 7. 1980-08-28. PMID:7384844. |
we think that biochemical abnormalities in the basal ganglia are responsible for the dyskinesias and submit data suggesting a reduction of dopamine turnover in the central nervous system of one patient. |
1980-08-28 |
2023-08-12 |
Not clear |
| N G Bacopoulos, D E Redmond, J Baulu, R H Rot. Chronic haloperidol or fluphenazine: effects on dopamine metabolism in brain, cerebrospinal fluid and plasma of Cercopithecus aethiops (vervet monkey). The Journal of pharmacology and experimental therapeutics. vol 212. issue 1. 1980-03-24. PMID:6766186. |
it is concluded that chronically increased dopamine metabolite production in the basal ganglia but not in cortex is reflected by increases in the hva level of cerebrospinal fluid and plasma and is accompanied by severe extrapyramidal side effects. |
1980-03-24 |
2023-08-12 |
monkey |
| M Stachowiak, J Białowas, M K Jurkowski, J Miros. Hunger induced changes in the noradrenaline and dopamine contents in various nuclei of the limbic system in rats. Polish journal of pharmacology and pharmacy. vol 31. issue 4. 1980-03-17. PMID:316524. |
teh effect of 48 hr food deprivation on noradrenaline (na) and dopamine (da) content in the dorsomedial, ventromedial and arcuate hypothalamic nuclei, in the anterior and posterior part of medial forebrain bundle, in the medial preoptic region, nucleus of diagonal band (septum), and in the central, medial and basal nuclei of the amygdaloid complex was investigated by radioenzymatic assay. |
1980-03-17 |
2023-08-11 |
rat |
| E S Tolosa, C La. Meige disease: striatal dopaminergic preponderance. Neurology. vol 29. issue 8. 1979-09-27. PMID:379689. |
dysfunction of the basal ganglia, characterized by a state of striatal dopamine preponderance, probably underlies the dystonic spasms in meige disease. |
1979-09-27 |
2023-08-11 |
Not clear |
| J D Parke. Bromocriptine in the treatment of parkinsonism. Drugs. vol 17. issue 5. 1979-09-17. PMID:37066. |
changes in movement are accompanied by biochemical changes in the central nervous system, consistent with the idea that bromocriptine has a dopamine agonist action in the basal ganglia and also in the mesolimbic system and hypothalamus. |
1979-09-17 |
2023-08-11 |
Not clear |
| G Curzo. The biochemistry of the basal ganglia and Parkinson's disease. Postgraduate medical journal. vol 53. issue 626. 1978-04-17. PMID:24209. |
while dopamine synthesis in the basal ganglia is defective in this condition, abnormalities of other transmitters occur, and their possible significance is discussed. |
1978-04-17 |
2023-08-11 |
Not clear |
| D Tarsy, R J Baldessarin. The pathophysiologic basis of tardive dyskinesia. Biological psychiatry. vol 12. issue 3. 1977-08-12. PMID:194633. |
a currently popular hypothesis is that there may be a functional excess in the activity of dopamine (da) as a synaptic neurotransmitter in the basal ganglia. |
1977-08-12 |
2023-08-11 |
Not clear |
| K Izumi, T Motomatsu, M Chrétie. Beta-endorphin induced akinesia in rats: effect of apomorhine and alpha-methyl-p-tyrosine and related modifications of dopamine turnover in the basal ganglia. Life sciences. vol 20. issue 7. 1977-05-27. PMID:557716. |
beta-endorphin induced akinesia in rats: effect of apomorhine and alpha-methyl-p-tyrosine and related modifications of dopamine turnover in the basal ganglia. |
1977-05-27 |
2023-08-11 |
rat |
| J Gerlac. Relationship between tardive dyskinesia, L-Dopa-induced hyperkinesia and parkinsonism. Psychopharmacology. vol 51. issue 3. 1977-05-20. PMID:403541. |
it is concluded that the irreversible neurotoxic effect of neuroleptic drugs may be associated with age-related changes in the oral somatotopic region of the basal ganglia (to be given consideration in any future search for the pathogenetic process underlying irreversible tardive dyskinesia), and that the pathophysiology of involuntary hyperkinesia in neuroleptic-treated psychiatric patients and in l-dopatreated parkinson patients may consist of a primary dopamine deficiency (pharmacological or structural), and a secondary relative hyperactivity in the dopaminergic system ("dopaminergic hypersensitivity") possibly corresponding to hypoactivity in the cholinergic system. |
1977-05-20 |
2023-08-11 |
Not clear |
| V Kristensen, M Olsen, A Theilgaar. Levodopa treatment of presenile dementia. Acta psychiatrica Scandinavica. vol 55. issue 1. 1977-04-25. PMID:842382. |
in parkinson's disease as well as presenile dementia there is a dopamine deficit in the basal ganglia. |
1977-04-25 |
2023-08-11 |
Not clear |
| A Carlsso. Some aspects of dopamine in the basal ganglia. Research publications - Association for Research in Nervous and Mental Disease. vol 55. 1977-02-24. PMID:12545. |
some aspects of dopamine in the basal ganglia. |
1977-02-24 |
2023-08-11 |
Not clear |
| R Mille. Schizophrenic psychology, associative learning and the role of forebrain dopamine. Medical hypotheses. vol 2. issue 5. 1976-11-21. PMID:9558. |
it is tentatively suggested that recognition of association of related features of the environment, whether in humans or animals occurs in the basal ganglia by a dopamine dependent process. |
1976-11-21 |
2023-08-11 |
Not clear |
| A Carlsson, B Winbla. Influence of age and time interval between death and autopsy on dopamine and 3-methoxytyramine levels in human basal ganglia. Journal of neural transmission. vol 38. issue 3-4. 1976-10-20. PMID:956813. |
influence of age and time interval between death and autopsy on dopamine and 3-methoxytyramine levels in human basal ganglia. |
1976-10-20 |
2023-08-11 |
human |
| P Powers, T S Douglass, R Wazir. Hyperpyrexia in catatonic states. Diseases of the nervous system. vol 37. issue 6. 1976-08-23. PMID:1277987. |
the role of dopamine in the basal ganglia in the etiology of catatonic states and its possible relationship to the symptomatology of the patient and his response to ect is discussed. |
1976-08-23 |
2023-08-11 |
Not clear |
| A W McArthur, M Pollock, N A Smid. Combined therapy with tetrabenazine and pimozide in Huntington's chorea: pilot study. The New Zealand medical journal. vol 83. issue 558. 1976-08-02. PMID:131917. |
current medication for huntingtons chorea is based on compounds which affect the activity of acetylcholine and dopamine in the basal ganglia and is unsatisfactory. |
1976-08-02 |
2023-08-11 |
Not clear |
| J A Milson, C J Pycoc. Effects of drugs acting on cerebral 5-hydroxytryptamine mechanisms on dopamine-dependent turning behaviour in mice. British journal of pharmacology. vol 56. issue 1. 1976-05-20. PMID:130178. |
the possible physiological relationship between dopamine and 5-hydroxytryptamine neurones in the basal ganglia is discussed. |
1976-05-20 |
2023-08-11 |
mouse |