| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Koch, M Bubse. Deficient sensorimotor gating after 6-hydroxydopamine lesion of the rat medial prefrontal cortex is reversed by haloperidol. The European journal of neuroscience. vol 6. issue 12. 1995-05-05. PMID:7704295. |
the present study sought to test the hypothesis that dopamine in the prefrontal cortex exerts an inhibitory influence on subcortical dopamsine systems and that depletion of prefrontal dopamine may affect behaviour via an increase in dopamine release in the basal ganglia. |
1995-05-05 |
2023-08-12 |
rat |
| M Koch, M Bubse. Deficient sensorimotor gating after 6-hydroxydopamine lesion of the rat medial prefrontal cortex is reversed by haloperidol. The European journal of neuroscience. vol 6. issue 12. 1995-05-05. PMID:7704295. |
the inhibition of the acoustic startle response by a preceding non-startling stimulus, as the behavioural test, because this phenomenon of sensorimotor gating is modified in opposite directions by dopamine in the prefrontal cortex and in the basal ganglia. |
1995-05-05 |
2023-08-12 |
rat |
| M Herrera-Marschitz, C F Loidl, Z B You, K Andersson, R Silveira, W T O'Connor, M Goin. Neurocircuitry of the basal ganglia studied by monitoring neurotransmitter release. Effects of intracerebral and perinatal asphyctic lesions. Molecular neurobiology. vol 9. issue 1-3. 1995-04-18. PMID:7888094. |
the neurocircuitries of the basal ganglia are studied with in vivo microdialysis, with special consideration to dopamine transmission and its interaction with other neurotransmitter systems. |
1995-04-18 |
2023-08-12 |
Not clear |
| H Hall, G Sedvall, O Magnusson, J Kopp, C Halldin, L Fard. Distribution of D1- and D2-dopamine receptors, and dopamine and its metabolites in the human brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 11. issue 4. 1995-03-21. PMID:7531978. |
both dopamine receptor subtypes, as well as dopamine, hva and dopac, were primarily found in the basal ganglia. |
1995-03-21 |
2023-08-12 |
human |
| C Hublin, J Launes, P Nikkinen, M Partine. Dopamine D2-receptors in human narcolepsy: a SPECT study with 123I-IBZM. Acta neurologica Scandinavica. vol 90. issue 3. 1995-03-06. PMID:7847059. |
increased dopamine d2 receptor binding in basal ganglia has been reported in human narcolepsy. |
1995-03-06 |
2023-08-12 |
human |
| W Löscher, R Annies, A Richte. Marked regional disturbances in brain metabolism of monoaminergic neurotransmitters in the genetically dystonic hamster. Brain research. vol 658. issue 1-2. 1995-03-02. PMID:7834342. |
the neurochemical data show that except for a significant decrease of dopamine and hva in the olfactory bulb, no consistent changes in dopamine metabolism are present across brain regions, including the basal ganglia, of dystonic hamsters. |
1995-03-02 |
2023-08-12 |
Not clear |
| E F Ball, P J Shaw, P G Ince, M Johnso. The distribution of excitatory amino acid receptors in the normal human midbrain and basal ganglia with implications for Parkinson's disease: a quantitative autoradiographic study using [3H]MK-801, [3H]glycine, [3H]CNQX and [3H]kainate. Brain research. vol 658. issue 1-2. 1995-03-02. PMID:7834343. |
in addition, perturbation of glutamate neurotransmission resulting from dopamine depletion in the basal ganglia is likely to contribute to the clinical manifestations of motor dysfunction. |
1995-03-02 |
2023-08-12 |
human |
| G Schlaug, H Hefter, B Nebeling, V Engelbrecht, P Weiss, G Stöcklin, R J Seit. Dopamine D2 receptor binding and cerebral glucose metabolism recover after D-penicillamine-therapy in Wilson's disease. Journal of neurology. vol 241. issue 10. 1995-02-27. PMID:7836960. |
it is hypothesized that recovery of motor functions due to copper trapping therapy was associated with an increase in basal ganglia activity and a re-expression or upregulation of dopamine d2 receptors. |
1995-02-27 |
2023-08-12 |
Not clear |
| A E Johnson, H Coirini, L Källström, F A Wiese. Characterization of dopamine receptor binding sites in the subthalamic nucleus. Neuroreport. vol 5. issue 14. 1995-02-22. PMID:7827344. |
experiments were undertaken to determine the distribution and binding profile of dopamine (da) receptors within a key extra-striatal region of the rat basal ganglia, the subthalamic nucleus (sth). |
1995-02-22 |
2023-08-12 |
rat |
| J N Joyc. The dopamine hypothesis of schizophrenia: limbic interactions with serotonin and norepinephrine. Psychopharmacology. vol 112. issue 1 Suppl. 1995-02-22. PMID:7831438. |
thus, evidence for the dopamine hypothesis has been derived from studies of the basal ganglia in schizophrenic cases and infrequently from other (e.g. |
1995-02-22 |
2023-08-12 |
human |
| R M Ridle. The psychology of perserverative and stereotyped behaviour. Progress in neurobiology. vol 44. issue 2. 1995-02-17. PMID:7831478. |
it is supposed that the level of dopamine activity in the basal ganglia affects the baseline level of behavioural activation such that excess activation results in the excessive execution of the most probable response to the environment to the exclusion of other possibilities (i.e. |
1995-02-17 |
2023-08-12 |
Not clear |
| R M Ridle. The psychology of perserverative and stereotyped behaviour. Progress in neurobiology. vol 44. issue 2. 1995-02-17. PMID:7831478. |
the symptoms of pd result from inadequate levels of dopamine in the basal ganglia while the stimulant psychoses result from excessive availability of dopamine. |
1995-02-17 |
2023-08-12 |
Not clear |
| R M Wu, K P Mohanakumar, D L Murphy, C C Chiue. Antioxidant mechanism and protection of nigral neurons against MPP+ toxicity by deprenyl (selegiline). Annals of the New York Academy of Sciences. vol 738. 1995-02-17. PMID:7832430. |
these findings indicate that the cytotoxic hydroxyl radical generated from dopamine oxidation in the iron-rich basal ganglia may contribute to the mechanism underlying the selective a9 melanized nigral degeneration in mptp-parkinsonism and possibly in idiopathic parkinson's disease. |
1995-02-17 |
2023-08-12 |
rat |
| C C Chiueh, R M Wu, K P Mohanakumar, L M Sternberger, G Krishna, T Obata, D L Murph. In vivo generation of hydroxyl radicals and MPTP-induced dopaminergic toxicity in the basal ganglia. Annals of the New York Academy of Sciences. vol 738. 1995-02-17. PMID:7832434. |
these results indicate that nonenzymatic and/or enzymatic oxidation of the dopamine released by mptp analogues in the extracellular fluid may play a key role in the generation of .oh free radicals in the iron-rich basal ganglia. |
1995-02-17 |
2023-08-12 |
Not clear |
| M Kato, N Miyashita, O Hikosaka, M Matsumura, S Usui, A Kor. Eye movements in monkeys with local dopamine depletion in the caudate nucleus. I. Deficits in spontaneous saccades. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 1 Pt 2. 1995-02-16. PMID:7823189. |
dopamine is known to exert powerful modulatory effects on the basal ganglia function, but its nature and mechanism are still unclear, especially in relation to voluntary behavior. |
1995-02-16 |
2023-08-12 |
monkey |
| C A Altar, C B Boylan, M Fritsche, C Jackson, C Hyman, R M Lindsa. The neurotrophins NT-4/5 and BDNF augment serotonin, dopamine, and GABAergic systems during behaviorally effective infusions to the substantia nigra. Experimental neurology. vol 130. issue 1. 1995-02-14. PMID:7821394. |
this has prompted the in vivo study of their effects on behavior and neuro-chemical parameters associated with dopamine, serotonin, and gabaergic neurons in the basal ganglia. |
1995-02-14 |
2023-08-12 |
rat |
| M B Youdim, J P Finber. Pharmacological actions of l-deprenyl (selegiline) and other selective monoamine oxidase B inhibitors. Clinical pharmacology and therapeutics. vol 56. issue 6 Pt 2. 1995-01-18. PMID:7995014. |
although not all features of its antiparkinson action are known, studies that used brains obtained at autopsy from patients who took l-deprenyl show that the selective inhibition of mao-b with a concomitant increase of phenylethylamine and dopamine, but not of serotonin or noradrenaline, in the basal ganglia may be responsible for its mode of action. |
1995-01-18 |
2023-08-12 |
Not clear |
| K W Lange, P Riederer, M B Youdi. Biochemical actions of l-deprenyl (selegiline). Clinical pharmacology and therapeutics. vol 56. issue 6 Pt 2. 1995-01-18. PMID:7995015. |
because parkinson's disease is characterized by a decrease in dopaminergic neurotransmission in the basal ganglia, the selective inhibition of mao-b should lead to diminished metabolism of dopamine in the nigrostriatal system and a significant increase in the concentration of the neurotransmitter. |
1995-01-18 |
2023-08-12 |
human |
| K X Huang, J R Walter. Electrophysiological effects of SKF 38393 in rats with reserpine treatment and 6-hydroxydopamine-induced nigrostriatal lesions reveal two types of plasticity in D1 dopamine receptor modulation of basal ganglia output. The Journal of pharmacology and experimental therapeutics. vol 271. issue 3. 1995-01-17. PMID:7996456. |
to examine the role of d1 dopamine receptors in modulating basal ganglia output and how this role may be altered by changes in dopaminergic transmission, the effects of a d1 dopamine agonist on firing rates of substantia nigra pars reticulata (snpr) neurons were determined in reserpine-treated rats and compared with effects observed in nigrostriatal-lesioned and normal rats. |
1995-01-17 |
2023-08-12 |
rat |
| K X Huang, J R Walter. Electrophysiological effects of SKF 38393 in rats with reserpine treatment and 6-hydroxydopamine-induced nigrostriatal lesions reveal two types of plasticity in D1 dopamine receptor modulation of basal ganglia output. The Journal of pharmacology and experimental therapeutics. vol 271. issue 3. 1995-01-17. PMID:7996456. |
current models of basal ganglia function predict that d1 dopamine agonists should reduce activity in the snpr, because d1 dopamine receptors on striatonigral neurons are thought to stimulate striatonigral firing rates and to enhance the release of tau-aminobutyric acid in the snpr. |
1995-01-17 |
2023-08-12 |
rat |