| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Burton D Beakley, Adam M Kaye, Alan D Kay. Tramadol, Pharmacology, Side Effects, and Serotonin Syndrome: A Review. Pain physician. vol 18. issue 4. 2016-02-17. PMID:26218943. |
serotonin syndrome is a mild to potentially life-threatening syndrome associated with excessive serotonergic activity within the central nervous system. |
2016-02-17 |
2023-08-13 |
Not clear |
| Andras David Nagy, Ayaka Iwamoto, Misato Kawai, Ryosei Goda, Haruka Matsuo, Tsuyoshi Otsuka, Mao Nagasawa, Mitsuhiro Furuse, Shinobu Yasu. Melatonin adjusts the expression pattern of clock genes in the suprachiasmatic nucleus and induces antidepressant-like effect in a mouse model of seasonal affective disorder. Chronobiology international. vol 32. issue 4. 2016-02-16. PMID:25515595. |
melatonin treatments altered the expression of genes of serotonergic neurotransmission in the dorsal raphe (tph2, sert, vmat2 and 5ht1a) and serotonin contents in the amygdala. |
2016-02-16 |
2023-08-13 |
mouse |
| Janina Deusser, Stefanie Schmidt, Benjamin Ettle, Sonja Plötz, Sabine Huber, Christian P Müller, Eliezer Masliah, Jürgen Winkler, Zacharias Koh. Serotonergic dysfunction in the A53T alpha-synuclein mouse model of Parkinson's disease. Journal of neurochemistry. vol 135. issue 3. 2016-02-10. PMID:26201615. |
a loss of serotonergic neurons or their projections into the hippocampus and alterations in serotonin release may be linked to these symptoms. |
2016-02-10 |
2023-08-13 |
mouse |
| Tarun E Hutchinson, Weixia Zhong, Seetha Chebolu, Sean M Wilson, Nissar A Darman. L-type calcium channels contribute to 5-HT3-receptor-evoked CaMKIIα and ERK activation and induction of emesis in the least shrew (Cryptotis parva). European journal of pharmacology. vol 755. 2016-02-09. PMID:25748600. |
activation of serotonergic 5-ht3 receptors by its selective agonist 2-methyl serotonin (2-me-5-ht) induces vomiting, which is sensitive to selective antagonists of both 5-ht3 receptors (palonosetron) and l-type calcium channels (ltcc) (amlodipine or nifedipine). |
2016-02-09 |
2023-08-13 |
Not clear |
| H Lefebvre, C Duparc, G Prévost, M C Zennaro, J Bertherat, E Louise. Paracrine control of steroidogenesis by serotonin in adrenocortical neoplasms. Molecular and cellular endocrinology. vol 408. 2016-02-08. PMID:25433205. |
altogether, these data support the concept of adrenal serotonergic paracrinopathy and suggest that 5-ht and its receptors may constitute valuable targets for pharmacological treatments of primary adrenal diseases. |
2016-02-08 |
2023-08-13 |
human |
| Yan Jin, Bin Luo, Yan-Yan Su, Xin-Xing Wang, Liang Chen, Ming Wang, Wei-Wen Wang, Lin Che. Sodium salicylate suppresses GABAergic inhibitory activity in neurons of rodent dorsal raphe nucleus. PloS one. vol 10. issue 5. 2016-02-03. PMID:25962147. |
sodium salicylate (nasal), a tinnitus inducing agent, can activate serotonergic (5-htergic) neurons in the dorsal raphe nucleus (drn) and can increase serotonin (5-ht) level in the inferior colliculus and the auditory cortex in rodents. |
2016-02-03 |
2023-08-13 |
mouse |
| Sung Ho Jang, Yong Min Kwon, Min Cheol Chan. Serotonin syndrome in stroke patients. Journal of rehabilitation medicine. vol 47. issue 3. 2016-02-02. PMID:25483226. |
serotonin syndrome is a potentially life-threatening condition that can be caused by administration of agents that increase serotonergic activity in the brain. |
2016-02-02 |
2023-08-13 |
Not clear |
| Michio Nomura, Masayuki Kaneko, Yasunobu Okuma, Jun Nomura, Ichiro Kusumi, Tsukasa Koyama, Yasuyuki Nomur. Involvement of serotonin transporter gene polymorphisms (5-HTT) in impulsive behavior in the japanese population. PloS one. vol 10. issue 3. 2016-01-28. PMID:25775400. |
the serotonergic pathway has been implicated in the pathogenesis of impulsivity, and sensitivity to aversive outcomes may be linked to serotonin (5-ht) levels. |
2016-01-28 |
2023-08-13 |
human |
| Giuseppe Musumeci, Rosa Imbesi, Francesca Maria Trovato, Marta Anna Szychlinska, Flavia Concetta Aiello, Pietro Buffa, Paola Castrogiovann. Importance of serotonin (5-HT) and its precursor l-tryptophan for homeostasis and function of skeletal muscle in rats. A morphological and endocrinological study. Acta histochemica. vol 117. issue 3. 2016-01-27. PMID:25805417. |
serotonin (5-ht) is a neurotransmitter, synthesized in serotonergic neurons of the central nervous system and in enterochromaffin cells of the gastrointestinal tract, which is involved in the regulation of several body functions, including muscle tissue development and growth and its contractile response. |
2016-01-27 |
2023-08-13 |
rat |
| Dario Arnaldi, Francesco Famà, Fabrizio De Carli, Silvia Morbelli, Michela Ferrara, Agnese Picco, Jennifer Accardo, Alberto Primavera, Gianmario Sambuceti, Flavio Nobil. The Role of the Serotonergic System in REM Sleep Behavior Disorder. Sleep. vol 38. issue 9. 2016-01-14. PMID:25845692. |
rem sleep behavior disorder (rbd) can be induced by antidepressants, especially serotonin reuptake inhibitors (ssri), thus a role of the serotonergic system in the pathogenesis of rbd has been proposed. |
2016-01-14 |
2023-08-13 |
human |
| Fosco Bernasconi, Michael Kometer, Thomas Pokorny, Erich Seifritz, Franz X Vollenweide. The electrophysiological effects of the serotonin 1A receptor agonist buspirone in emotional face processing. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 4. 2016-01-11. PMID:25637265. |
emotional face processing is critically modulated by the serotonergic system, and serotonin (5-ht) receptor agonists impair emotional face processing. |
2016-01-11 |
2023-08-13 |
Not clear |
| Nicholas J Jury, Betsy A McCormick, Nelson D Horseman, Stephen C Benoit, Karen A Gregerso. Enhanced responsiveness to selective serotonin reuptake inhibitors during lactation. PloS one. vol 10. issue 2. 2016-01-11. PMID:25689282. |
serotonergic mechanisms and their dysfunction are widely presumed to be involved, which has led us to investigate whether lactation induces changes in central or peripheral serotonin (5-ht) systems and related affective behaviors. |
2016-01-11 |
2023-08-13 |
mouse |
| Marin M Jukic, Tania Carrillo-Roa, Michal Bar, Gal Becker, Vukasin M Jovanovic, Ksenija Zega, Elisabeth B Binder, Claude Brodsk. Abnormal development of monoaminergic neurons is implicated in mood fluctuations and bipolar disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 4. 2016-01-05. PMID:25241801. |
during embryogenesis, the transcription factor otx2 orchestrates the genetic networks directing the specification of dopaminergic (da) and serotonergic (5-ht) neurons. |
2016-01-05 |
2023-08-13 |
mouse |
| Yann S Mineur, Emily B Einstein, Matthew P Bentham, Mattis B Wigestrand, Sam Blakeman, Sylvia A Newbold, Marina R Picciott. Expression of the 5-HT1A serotonin receptor in the hippocampus is required for social stress resilience and the antidepressant-like effects induced by the nicotinic partial agonist cytisine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 4. 2016-01-05. PMID:25288485. |
this study suggests that serotonin signaling through postsynaptic 5-ht1a receptors in the hippocampus is critical for the antidepressant-like effects of a cholinergic drug and begins to elucidate the molecular mechanisms underlying interactions between the serotonergic and cholinergic systems related to mood disorders. |
2016-01-05 |
2023-08-13 |
mouse |
| Lucina E Lizarraga, Aram B Cholanians, Andy V Phan, Joseph M Herndon, Serrine S Lau, Terrence J Monk. Vesicular monoamine transporter 2 and the acute and long-term response to 3,4-(±)-methylenedioxymethamphetamine. Toxicological sciences : an official journal of the Society of Toxicology. vol 143. issue 1. 2016-01-05. PMID:25370842. |
conversely, the long-term effects of mdma manifest as prolonged depletions in 5-ht, and reductions in 5-ht reuptake transporter (sert), indicative of serotonergic neurotoxicity. |
2016-01-05 |
2023-08-13 |
rat |
| Nicole E De Long, Rebecca A Stepita, Valerie H Taylor, Alison C Hollowa. Major depressive disorder and diabetes: does serotonin bridge the gap? Current diabetes reviews. vol 11. issue 2. 2016-01-04. PMID:25705990. |
this review will focus on 1) the evidence from human and animal studies suggesting a link between the use of antidepressants that target serotonin signaling (i.e., ssris, serotonin-norepinephrine reuptake inhibitors (snris), serotonin antagonist and reuptake inhibitors (saris), and noradrenergic and specific serotonergic antidepressants (nassas)) and increased risk of diabetes, and 2) the mechanisms by which alterations in serotonin signalling by antidepressants can affect glucose homeostasis. |
2016-01-04 |
2023-08-13 |
human |
| Hector Mateo-Carrasco, Eva María Muñoz-Aguilera, Juan Manuel García-Torrecillas, Hiba Abu Al-Rob. Serotonin syndrome probably triggered by a morphine-phenelzine interaction. Pharmacotherapy. vol 35. issue 6. 2016-01-04. PMID:25903219. |
serotonin syndrome is a potentially life-threatening condition caused by excessive central and peripheral stimulation of serotonin brainstem receptors, usually triggered by inadvertent interactions between agents with serotonergic activity. |
2016-01-04 |
2023-08-13 |
Not clear |
| Jeremiah Y Cohen, Mackenzie W Amoroso, Naoshige Uchid. Serotonergic neurons signal reward and punishment on multiple timescales. eLife. vol 4. 2015-12-23. PMID:25714923. |
one challenge in testing the numerous hypotheses about serotonin's function has been observing the activity of identified serotonergic neurons in animals engaged in behavioral tasks. |
2015-12-23 |
2023-08-13 |
mouse |
| M Kesic, A Tvrdeic, D Kolaric, R Stojkovic, L Cicin-Sai. Serotonergic modulation of pain and analgesic responses: a study in rats with constitutionally altered serotonin transporters. European journal of pain (London, England). vol 19. issue 4. 2015-12-22. PMID:25070859. |
serotonergic modulation of pain and analgesic responses: a study in rats with constitutionally altered serotonin transporters. |
2015-12-22 |
2023-08-13 |
rat |
| M Kesic, A Tvrdeic, D Kolaric, R Stojkovic, L Cicin-Sai. Serotonergic modulation of pain and analgesic responses: a study in rats with constitutionally altered serotonin transporters. European journal of pain (London, England). vol 19. issue 4. 2015-12-22. PMID:25070859. |
a role of the serotonin (5ht) transporter, a key regulator of serotonergic transmission, in the physiology, pharmacology and genetics of pain responses has been proposed recently. |
2015-12-22 |
2023-08-13 |
rat |