| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Koilmani Emmanuvel Rajan, Jayakumar Preethi, Hemant K Sing. Molecular and Functional Characterization of Bacopa monniera: A Retrospective Review. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-09-28. PMID:26413131. |
this review focuses on the studies which trace the effect of bacopa treatment on serotonergic system and 5-ht mediated key molecular changes that are associated with memory formation. |
2015-09-28 |
2023-08-13 |
Not clear |
| Raffaele Nardone, Yvonne Höller, Aljoscha Thomschewski, Peter Höller, Piergiorgio Lochner, Stefan Golaszewski, Francesco Brigo, Eugen Trink. Serotonergic transmission after spinal cord injury. Journal of neural transmission (Vienna, Austria : 1996). vol 122. issue 2. 2015-09-25. PMID:24866695. |
there are functional relevant connections between the descending serotonergic system from the rostral ventromedial medulla in the brainstem, the 5-ht receptors in the spinal dorsal horn, and the descending pain facilitation after tissue and nerve injury. |
2015-09-25 |
2023-08-13 |
Not clear |
| Matthias Liecht. Novel psychoactive substances (designer drugs): overview and pharmacology of modulators of monoamine signaling. Swiss medical weekly. vol 145. 2015-09-25. PMID:25588018. |
typically, stimulants inhibit the transport of dopamine and noradrenaline (pipradrols, pyrovalerone cathinones) or induce the release of these monoamines (amphetamines and methamphetamine-like cathinones), entactogens predominantly enhance serotonin release (phenylpiperazines, aminoindanes, para-substituted amphetamines, and mdma-like cathinones) similar to mdma (ecstasy), and hallucinogens (tryptamines, hallucinogenic phenethylamines) are direct agonists at serotonergic 5-ht2a receptors. |
2015-09-25 |
2023-08-13 |
Not clear |
| Matthias Liecht. Novel psychoactive substances (designer drugs): overview and pharmacology of modulators of monoamine signaling. Swiss medical weekly. vol 145. 2015-09-25. PMID:25588018. |
serotonergic drugs (entactogens and hallucinogens) are associated with acute serotonin syndrome, hyperthermia, seizures, and hyponatremia. |
2015-09-25 |
2023-08-13 |
Not clear |
| Robert J Carey, Ernest N Damianopoulo. Serotonin and conditioning: focus on Pavlovian psychostimulant drug conditioning. Behavioural brain research. vol 282. 2015-09-21. PMID:25446748. |
in this article we review the basics of conditioning as well as the serotonergic system and point up the number of non-associative ways in which manipulations of serotonin neurotransmission have an impact upon conditioning. |
2015-09-21 |
2023-08-13 |
Not clear |
| Yoshikage Muroi, Toshiaki Ishi. Neuropeptide Y is crucial for nutritional state-dependent regulation of maternal behavior. Psychoneuroendocrinology. vol 51. 2015-09-21. PMID:25462911. |
in contrast, injection of the npy y1 receptor antagonist bibp-3226 into the drn, in which the expression of the y1 receptor was confirmed in serotonergic (5-ht) and gabaergic interneurons, recovered the expression of maternal behavior in fasted dams. |
2015-09-21 |
2023-08-13 |
Not clear |
| Martin Häring, Vanessa Enk, Alejandro Aparisi Rey, Sebastian Loch, Inigo Ruiz de Azua, Tillmann Weber, Dusan Bartsch, Krisztina Monory, Beat Lut. Cannabinoid type-1 receptor signaling in central serotonergic neurons regulates anxiety-like behavior and sociability. Frontiers in behavioral neuroscience. vol 9. 2015-09-21. PMID:26388750. |
in order to substantiate the physiological role of the cb1 receptor in serotonergic neurons of the raphe nuclei, we generated serotonergic 5-hydroxytryptamine (5-ht) neuron-specific cb 1 receptor-deficient mice, using the cre/loxp system with a tamoxifen-inducible cre recombinase under the control of the regulatory sequences of the tryptophan hydroxylase 2 gene (tph2-creer (t2)), thus, restricting the recombination to 5-ht neurons of the central nervous system (cns). |
2015-09-21 |
2023-08-13 |
mouse |
| Yuyu Kunimura, Kinuyo Iwata, Norio Iijima, Makito Kobayashi, Hitoshi Ozaw. Effect of sex steroid hormones on the number of serotonergic neurons in rat dorsal raphe nucleus. Neuroscience letters. vol 594. 2015-09-14. PMID:25827489. |
many studies have reported a relationship between sex steroid hormones and the brain serotonergic system; however, the interaction between sex steroid hormones and the number of brain neurons expressing serotonin has not yet been elucidated. |
2015-09-14 |
2023-08-13 |
rat |
| Yuyu Kunimura, Kinuyo Iwata, Norio Iijima, Makito Kobayashi, Hitoshi Ozaw. Effect of sex steroid hormones on the number of serotonergic neurons in rat dorsal raphe nucleus. Neuroscience letters. vol 594. 2015-09-14. PMID:25827489. |
our results suggest that, the sexual dimorphism observed in the serotonergic system is due to factors such as 5-ht synthesis, transportation, and degradation but not to the number of serotonergic neurons. |
2015-09-14 |
2023-08-13 |
rat |
| Luise Liebig, Andreas von Ameln-Mayerhofer, Harald Hentschk. MDMA modulates spontaneous firing of subthalamic nucleus neurons in vitro. Experimental brain research. vol 233. issue 1. 2015-09-10. PMID:25234400. |
3,4-methylene-dioxy-n-methylamphetamine (mdma, 'ecstasy') has a broad spectrum of molecular targets in the brain, among them receptors and transporters of the serotonergic (5-hydroxytryptamine, 5-ht) and noradrenergic systems. |
2015-09-10 |
2023-08-13 |
Not clear |
| M Barann, U M Stamer, M Lyutenska, F Stüber, H Bönisch, B Urba. Effects of opioids on human serotonin transporters. Naunyn-Schmiedeberg's archives of pharmacology. vol 388. issue 1. 2015-09-10. PMID:25332055. |
this inhibition may contribute to serotonergic effects when these opioids are given in combination, e.g., with monoamine oxidase inhibitors or selective serotonin reuptake inhibitors. |
2015-09-10 |
2023-08-13 |
human |
| Christian P Müller, Judith R Homber. The role of serotonin in drug use and addiction. Behavioural brain research. vol 277. 2015-09-08. PMID:24769172. |
here we review the role of the serotonergic (5-ht) system in the establishment of drug use-associated behaviours on the one hand and the transition and maintenance of addiction on the other hand for the drugs: cocaine, amphetamine, methamphetamine, mdma (ecstasy), morphine/heroin, cannabis, alcohol, and nicotine. |
2015-09-08 |
2023-08-13 |
human |
| Lara-Jane Kepser, Judith R Homber. The neurodevelopmental effects of serotonin: a behavioural perspective. Behavioural brain research. vol 277. 2015-09-08. PMID:24859172. |
serotonin is well known for its role in psychiatric disorders like depression and autism, but it is less clear how aberrant behaviour associated with these disorders are shaped by serotonergic alterations during prenatal and postnatal development. |
2015-09-08 |
2023-08-13 |
Not clear |
| Lara-Jane Kepser, Judith R Homber. The neurodevelopmental effects of serotonin: a behavioural perspective. Behavioural brain research. vol 277. 2015-09-08. PMID:24859172. |
the studies together demonstrate that risk for mood disorders (including social deficits) is related to serotonergic perturbations during the prenatal and postnatal phases, whereas risk for autism-like features and sexual abnormalities increases when serotonin levels are increased during the postnatal period. |
2015-09-08 |
2023-08-13 |
Not clear |
| Caroline B Quines, Juliana T Da Rocha, Tuane B Sampaio, Ana Paula Pesarico, José S S Neto, Gilson Zeni, Cristina W Nogueir. Involvement of the serotonergic system in the anxiolytic-like effect of 2-phenylethynyl butyltellurium in mice. Behavioural brain research. vol 277. 2015-09-08. PMID:24928768. |
the involvement of the serotonergic system, synaptosomal [(3)h] serotonin (5-ht) uptake and monoamine oxidase (mao a and b) activities on cerebral cortices of mice, was examined. |
2015-09-08 |
2023-08-13 |
mouse |
| Caroline B Quines, Juliana T Da Rocha, Tuane B Sampaio, Ana Paula Pesarico, José S S Neto, Gilson Zeni, Cristina W Nogueir. Involvement of the serotonergic system in the anxiolytic-like effect of 2-phenylethynyl butyltellurium in mice. Behavioural brain research. vol 277. 2015-09-08. PMID:24928768. |
furthermore, pebt reduced [(3)h] 5-ht uptake and selectively inhibited mao-a activity in cerebral cortex, suggesting the involvement of the serotonergic system in the mechanism of action of this tellurium compound. |
2015-09-08 |
2023-08-13 |
mouse |
| Luciana Romina Frick, Micaela Bernardez-Vidal, Christian Hocht, Bonifacio Silvano Zanutto, Maximiliano Rapanell. Dual role of serotonin in the acquisition and extinction of reward-driven learning: involvement of 5-HT1A, 5-HT2A and 5-HT3 receptors. Behavioural brain research. vol 277. 2015-09-08. PMID:24949809. |
given that the major serotonergic circuit in the rat brain comprises the dorsal raphe nuclei and the medial prefrontal cortex (mpfc), and because the latter structure is involved in the control of complex behaviors and expresses 1a (5-ht1a), 2a (5-ht2a), and 3 (5-ht3) receptors, the aim was to study the role of 5-ht and of these receptors in the acquisition and extinction of a reward-dependent operant conditioning task. |
2015-09-08 |
2023-08-13 |
rat |
| Elizabeth P Baue. Serotonin in fear conditioning processes. Behavioural brain research. vol 277. 2015-09-08. PMID:25078294. |
the serotonergic system can be manipulated by administering serotonin receptor agonists and antagonists, as well as selective serotonin reuptake inhibitors (ssris), and these can have significant effects on emotional learning and memory. |
2015-09-08 |
2023-08-13 |
Not clear |
| Ryosei Goda, Tsuyoshi Otsuka, Ayaka Iwamoto, Misato Kawai, Satomi Shibata, Mitsuhiro Furuse, Shinobu Yasu. Serotonin levels in the dorsal raphe nuclei of both chipmunks and mice are enhanced by long photoperiod, but brain dopamine level response to photoperiod is species-specific. Neuroscience letters. vol 593. 2015-09-08. PMID:25797183. |
in both species, serotonin levels in the dorsal raphe nuclei were higher under long-day conditions than short-day conditions, suggesting a similarity in the photoperiod responses of the serotonergic systems. |
2015-09-08 |
2023-08-13 |
mouse |
| Anupam Kotwal, Sarah L Cutron. Serotonin Syndrome in the Setting of Lamotrigine, Aripiprazole, and Cocaine Use. Case reports in medicine. vol 2015. 2015-09-04. PMID:26339247. |
serotonin syndrome is a potentially life-threatening condition associated with increased serotonergic activity in the central nervous system. |
2015-09-04 |
2023-08-13 |
Not clear |