| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M P Johnson, D E Nichol. Comparative serotonin neurotoxicity of the stereoisomers of fenfluramine and norfenfluramine. Pharmacology, biochemistry, and behavior. vol 36. issue 1. 1990-07-11. PMID:2140899. |
with the exception of hippocampal 5-ht levels following d-fenfluramine treatment, there was a decrease in all the serotonergic markers assayed, following treatment with the d-enantiomers of fenfluramine and norfenfluramine. |
1990-07-11 |
2023-08-11 |
rat |
| N J Penington, J S Kell. Serotonin receptor activation reduces calcium current in an acutely dissociated adult central neuron. Neuron. vol 4. issue 5. 1990-07-05. PMID:2140514. |
the release of serotonin (5-ht) from the terminals of serotonergic (raphe) neurons is under inhibitory feed-back control. |
1990-07-05 |
2023-08-11 |
Not clear |
| N Gurevich, P H Wu, P L Carle. Serotonin agonist and antagonist actions in hippocampal CA1 neurons. Canadian journal of physiology and pharmacology. vol 68. issue 5. 1990-06-28. PMID:2340447. |
the long-lasting 5-ht hyperpolarization might be mediated by 5-ht1a receptor activation, and the short-lasting hyperpolarization by another serotonergic receptor subtype. |
1990-06-28 |
2023-08-11 |
Not clear |
| Z Xu, G Mondal, J P Song, R E Purd. Effect of ouabain on the rabbit ear artery contraction to serotonin: enhanced response mediated by serotonergic rather than alpha adrenergic receptors. The Journal of pharmacology and experimental therapeutics. vol 253. issue 2. 1990-06-21. PMID:2160006. |
effect of ouabain on the rabbit ear artery contraction to serotonin: enhanced response mediated by serotonergic rather than alpha adrenergic receptors. |
1990-06-21 |
2023-08-11 |
rabbit |
| R M Bowker, L C Abbot. Quantitative re-evaluation of descending serotonergic and non-serotonergic projections from the medulla of the rodent: evidence for extensive co-existence of serotonin and peptides in the same spinally projecting neurons, but not from the nucleus raphe magnus. Brain research. vol 512. issue 1. 1990-06-21. PMID:2337803. |
quantitative re-evaluation of descending serotonergic and non-serotonergic projections from the medulla of the rodent: evidence for extensive co-existence of serotonin and peptides in the same spinally projecting neurons, but not from the nucleus raphe magnus. |
1990-06-21 |
2023-08-11 |
Not clear |
| R M Bowker, L C Abbot. Quantitative re-evaluation of descending serotonergic and non-serotonergic projections from the medulla of the rodent: evidence for extensive co-existence of serotonin and peptides in the same spinally projecting neurons, but not from the nucleus raphe magnus. Brain research. vol 512. issue 1. 1990-06-21. PMID:2337803. |
the findings indicate that most (nearly 90%) of the medullary 5-ht neurons projected to the lumbar spinal cord, and most (up to 85%) of the spinally projecting neurons within the distribution of the serotonergic neurons contained 5-ht immunoreactivity. |
1990-06-21 |
2023-08-11 |
Not clear |
| N Toda, T Okamur. Comparison of the response to 5-carboxamidotryptamine and serotonin in isolated human, monkey and dog coronary arteries. The Journal of pharmacology and experimental therapeutics. vol 253. issue 2. 1990-06-21. PMID:2338652. |
in isolated dog coronary arteries, serotonin (5-ht) produced a contraction, whereas 5-carboxamidotryptamine (5-ct), a serotonergic 5-ht1-like receptor agonist, mainly relaxed the arteries, and the contraction, if any, was slight. |
1990-06-21 |
2023-08-11 |
human |
| F C Zhou, E C Azmiti. Neurotrophic factor for serotonergic neurons prevents degeneration of grafted raphe neurons in the cerebellum. Brain research. vol 507. issue 2. 1990-06-20. PMID:1692500. |
earlier studies in this laboratory have shown that partial serotonergic (5-ht) deafferentation from the hippocampus induced a homotypic sprouting. |
1990-06-20 |
2023-08-11 |
Not clear |
| J Aguilera, L A Lopez, E Yavi. Tetanus toxin-induced protein kinase C activation and elevated serotonin levels in the perinatal rat brain. FEBS letters. vol 263. issue 1. 1990-06-06. PMID:2332053. |
the data are consistent with the possibility that tetox acts effectively on the serotonergic innervation, presumably in conjunction with pkc to cause accumulation of serotonin. |
1990-06-06 |
2023-08-11 |
rat |
| D C Molliver, M E Mollive. Anatomic evidence for a neurotoxic effect of (+/-)-fenfluramine upon serotonergic projections in the rat. Brain research. vol 511. issue 1. 1990-06-04. PMID:2331614. |
immunocytochemistry was used to determine whether (+/-)-fenfluramine causes structural damage to serotonergic (5-ht) neurons. |
1990-06-04 |
2023-08-11 |
rat |
| J C Neill, S J Coope. Effects of 5-hydroxytryptamine and d-fenfluramine on sham feeding and sham drinking in the gastric-fistulated rat. Physiology & behavior. vol 46. issue 6. 1990-05-30. PMID:2634259. |
these are the first data to implicate serotonergic activity at peripherally located 5-ht receptors in the modulation of sucrose sham feeding. |
1990-05-30 |
2023-08-11 |
rat |
| P Wallén, J Christenson, L Brodin, R Hill, A Lansner, S Grillne. Mechanisms underlying the serotonergic modulation of the spinal circuitry for locomotion in lamprey. Progress in brain research. vol 80. 1990-05-30. PMID:2699371. |
the central nervous system of the lamprey contains serotonergic (5-hydroxytryptamine, 5-ht) neurones both in the spinal cord and in the brainstem. |
1990-05-30 |
2023-08-11 |
Not clear |
| J Hallman, E Sakurai, L Orelan. Blood platelet monoamine oxidase activity, serotonin uptake and release rates in anorexia and bulimia patients and in healthy controls. Acta psychiatrica Scandinavica. vol 81. issue 1. 1990-05-29. PMID:2330833. |
platelet monoamine oxidase (mao) activity, serotonin uptake rate and serotonin efflux rate have all been suggested to be markers for central serotonergic mechanisms. |
1990-05-29 |
2023-08-11 |
Not clear |
| T Tanabe, S Ueda, Y San. Immunohistochemical studies on the development of tyrosine hydroxylase- and serotonin-immunoreactive neurons in fetal dorsal raphe tissue transplanted into the anterior eye chamber of adult rats. Archives of histology and cytology. vol 52. issue 5. 1990-05-24. PMID:2576638. |
the differences between the developmental patterns of catecholaminergic and serotonergic neurons--especially the extension of their axonal processes--in the grafts were immunohistochemically examined using tyrosine hydroxylase (th) and serotonin antisera. |
1990-05-24 |
2023-08-11 |
rat |
| M B Campos, M L Vitale, R S Calandra, S R Chiocchi. Serotonergic innervation of the rat testis. Journal of reproduction and fertility. vol 88. issue 2. 1990-05-23. PMID:2325015. |
these results indicate that at least part of the testicular 5-ht derives from a serotonergic innervation of the gonad. |
1990-05-23 |
2023-08-11 |
rat |
| J Gonzalez-Heydrich, S J Peroutk. Serotonin receptor and reuptake sites: pharmacologic significance. The Journal of clinical psychiatry. vol 51 Suppl. 1990-05-11. PMID:2157701. |
the increasing ability to modulate serotonergic neurotransmission via distinct serotonin (5-ht) receptor subtypes should greatly facilitate the analysis of the role of 5-ht in both normal and abnormal human brain function. |
1990-05-11 |
2023-08-11 |
human |
| W A Hewlett, S Vinogradov, W S Agra. Clonazepam treatment of obsessions and compulsions. The Journal of clinical psychiatry. vol 51. issue 4. 1990-05-11. PMID:2182614. |
obsessive compulsive disorder has recently been successfully treated with antidepressants that selectively inhibit serotonin reuptake, and a serotonergic hypothesis related to the etiology and treatment of obsessive compulsive disorder has been proposed. |
1990-05-11 |
2023-08-11 |
Not clear |
| F D Yocca, R N Wright, R R Margraf, A S Eiso. 8-OH-DPAT and buspirone analogs inhibit the ketanserin-sensitive quipazine-induced head shake response in rats. Pharmacology, biochemistry, and behavior. vol 35. issue 1. 1990-04-26. PMID:2138331. |
behavioral syndromes mediated by serotonergic mechanisms may reflect interactions between distinct effects initiated by specific 5-ht receptors, such as the 5-ht1a and the 5-ht2 receptor. |
1990-04-26 |
2023-08-11 |
rat |
| P Hoffmann, J O Skarphedinsson, M Delle, P Thoré. Electrical stimulation of the gastrocnemius muscle in the spontaneously hypertensive rat increases the pain threshold: role of different serotonergic receptors. Acta physiologica Scandinavica. vol 138. issue 2. 1990-04-23. PMID:2138403. |
it was also shown that opioid and serotonergic (5-ht) systems were involved. |
1990-04-23 |
2023-08-11 |
rat |
| J Lappalainen, J Hietala, M Koulu, T Seppälä, B Sjöholm, E Syvälaht. Chronic treatment with SCH 23390 and haloperidol: effects on dopaminergic and serotonergic mechanisms in rat brain. The Journal of pharmacology and experimental therapeutics. vol 252. issue 2. 1990-04-16. PMID:2179533. |
effects of chronic administration (18 days) with sch 23390 (0.1 or 0.5 mg/kg/day s.c.) and haloperidol (1 mg/kg/day s.c.) on dopamine and serotonin synthesis and metabolism in discrete dopaminergic and serotonergic nuclei of rat brain were studied. |
1990-04-16 |
2023-08-11 |
rat |