| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J DeVeaugh-Geis. Pharmacologic therapy of obsessive compulsive disorder. Advances in pharmacology (San Diego, Calif.). vol 30. 1995-02-27. PMID:7833296. |
nevertheless, there may be a role for other serotonergic drugs in the treatment of ocd, particularly as adjunctive treatments used to enhance the effect of the serotonin uptake inhibitors. |
1995-02-27 |
2023-08-12 |
Not clear |
| S L Dewey, G S Smith, J Logan, D Alexoff, Y S Ding, P King, N Pappas, J D Brodie, C R Ashb. Serotonergic modulation of striatal dopamine measured with positron emission tomography (PET) and in vivo microdialysis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 1 Pt 2. 1995-02-16. PMID:7823183. |
the serotonergic system was manipulated by administration of the selective 5-ht reuptake inhibitor, citalopram, or by serotonergic (5-ht2) receptor blockade (using altanserin, a 5-ht2 antagonist). |
1995-02-16 |
2023-08-12 |
rat |
| G Srkalovic, M Selim, M A Rea, J D Glas. Serotonergic inhibition of extracellular glutamate in the suprachiasmatic nuclear region assessed using in vivo brain microdialysis. Brain research. vol 656. issue 2. 1995-02-14. PMID:7820591. |
in previous studies, we showed that localized perfusion of the scn region with serotonin (5-ht) or the non-selective serotonergic, quipazine, using the microdialysis technique significantly reduced the extracellular concentration of the excitatory amino acid (eaa), glutamate. |
1995-02-14 |
2023-08-12 |
Not clear |
| X D Martin, M C Brenna. Serotonin in human tears. European journal of ophthalmology. vol 4. issue 3. 1995-02-13. PMID:7819731. |
it has been postulated that serotonergic receptors are present in the corneal epithelium and that their activation by serotonin released from subepithelial corneal nerves raises the level of cyclic amp, which in turn stimulates active ci-secretion by the corneal epithelium. |
1995-02-13 |
2023-08-12 |
human |
| N Ozaki, N E Rosenthal, P Mazzola, C C Chiueh, T Hardin, D Garcia-Borreguero, P J Schwartz, E Turner, D A Oren, D L Murph. Platelet [3H]paroxetine binding, 5-HT-stimulated Ca2+ response, and 5-HT content in winter seasonal affective disorder. Biological psychiatry. vol 36. issue 7. 1995-02-09. PMID:7811842. |
the present study was designed to evaluate cellular serotonergic functions in winter seasonal affective disorder (sad) using serotonin (5-ht)-stimulated ca2+ response as an integrated measure of 5-ht2 receptor function in platelets, [3h]paroxetine binding to characterize the platelet 5-ht transporter and 5-ht content as an index of the platelet storage capacity for this neurotransmitter amine. |
1995-02-09 |
2023-08-12 |
Not clear |
| A D Levy, M H Baumann, L D Van de Ka. Monoaminergic regulation of neuroendocrine function and its modification by cocaine. Frontiers in neuroendocrinology. vol 15. issue 2. 1995-02-08. PMID:7813744. |
chronic cocaine exposure reduces some of the hormone responses to the serotonin (5-ht) releasers p-chloroamphetamine and d-fenfluramine, suggesting deficits in the functional status of serotonergic nerve terminals. |
1995-02-08 |
2023-08-12 |
human |
| H Movahedi, H T Le, H M Spanggord, R E Purd. Effect of alpha adrenergic agonist on the rabbit ear artery contraction to serotonin: enhanced response mediated by serotonergic1-like receptors. The Journal of pharmacology and experimental therapeutics. vol 272. issue 1. 1995-02-08. PMID:7815353. |
ketanserin (10 nm), ritanserin (50 nm) and mdl 72222 (1 microm) also had no effect on the amplified response, ruling out the involvement of serotonergic (5-ht)2 and 5-ht3 receptors. |
1995-02-08 |
2023-08-12 |
rabbit |
| W D Essman, A Singh, I Luck. Serotonergic properties of cocaine: effects on a 5-HT2 receptor-mediated behavior and on extracellular concentrations of serotonin and dopamine. Pharmacology, biochemistry, and behavior. vol 49. issue 1. 1995-02-07. PMID:7816859. |
serotonergic properties of cocaine: effects on a 5-ht2 receptor-mediated behavior and on extracellular concentrations of serotonin and dopamine. |
1995-02-07 |
2023-08-12 |
rat |
| D LeMarquand, R O Pihl, C Benkelfa. Serotonin and alcohol intake, abuse, and dependence: findings of animal studies. Biological psychiatry. vol 36. issue 6. 1995-02-01. PMID:7803601. |
despite a relatively large body of literature on the role of the neurotransmitter serotonin (5-hydroxytryptamine, or 5-ht) in the regulation of alcohol intake, the functional significance of serotonergic neurotransmission and its relationship to alcohol intake, abuse, and dependence remains to be fully elucidated. |
1995-02-01 |
2023-08-12 |
Not clear |
| D LeMarquand, R O Pihl, C Benkelfa. Serotonin and alcohol intake, abuse, and dependence: findings of animal studies. Biological psychiatry. vol 36. issue 6. 1995-02-01. PMID:7803601. |
it is concluded that serotonin mediates ethanol intake as a part of its larger role in behavior modulation, such that increases in serotonergic functioning decrease ethanol intake, and decreased serotonergic functioning increases ethanol intake. |
1995-02-01 |
2023-08-12 |
Not clear |
| O A De Leó. [The neurobiological bases of aggression: the pharmacotherapeutic implications]. Revista medica de Panama. vol 19. issue 2. 1995-01-11. PMID:7991801. |
drugs that enhance serotonin transmission are indicated in conditions related to decreased serotonergic transmission. |
1995-01-11 |
2023-08-12 |
Not clear |
| C D Kilt. Recent pharmacologic advances in antidepressant therapy. The American journal of medicine. vol 97. issue 6A. 1995-01-11. PMID:7992824. |
the serotonergic properties of newer generation antidepressants underscore the role of 5-hydroxytryptamine (5-ht, serotonin) in both the pathophysiology and the pharmacotherapy of major depression. |
1995-01-11 |
2023-08-12 |
Not clear |
| H Jeltsch, J C Cassel, R Jackisch, B Neufang, P L Greene, C Kelche, G Hertting, B Wil. Lesions of supracallosal or infracallosal hippocampal pathways in the rat: behavioral, neurochemical, and histochemical effects. Behavioral and neural biology. vol 62. issue 2. 1995-01-09. PMID:7993302. |
subsequently, histochemical or neurochemical determinations of cholinergic, serotonergic and noradrenergic hippocampal innervations were performed using acetylcholinesterase-staining, determination of high-affinity synaptosomal uptake of choline and serotonin, and measurement of hippocampal serotonin and noradrenaline concentrations by hplc methods. |
1995-01-09 |
2023-08-12 |
rat |
| J H Son, H Baker, D H Park, T H Jo. Drastic and selective hyperinnervation of central serotonergic neurons in a lethal neurodevelopmental mouse mutant, Anorexia (anx). Brain research. Molecular brain research. vol 25. issue 1-2. 1995-01-05. PMID:7984037. |
previous studies strongly suggested that the mutation results in elevated serotonergic stimulation, because these traits are characteristic of such overstimulation and because brain serotonin is believed to have an inhibitory effect on feeding behavior. |
1995-01-05 |
2023-08-12 |
mouse |
| Y Kobayashi, K Matsuyama, S Mor. Distribution of serotonin cells projecting to the pontomedullary reticular formation in the cat. Neuroscience research. vol 20. issue 1. 1995-01-05. PMID:7984340. |
using immunohistochemistry and retrograde transport techniques, this study demonstrates that serotonin (5-ht) cells in the dorsal tegmental gray of the pons at rostrocaudal from p1 to p6 levels are sources of bilateral serotonergic projections to the gigantocellular tegmental field of the medial pontine and medullary reticular formation in the cat. |
1995-01-05 |
2023-08-12 |
cat |
| A D Levy, Q Li, L D Van de Ka. Repeated cocaine exposure inhibits the adrenocorticotropic hormone response to the serotonin releaser d-fenfluramine and the 5-HT1A agonist, 8-OH-DPAT. Neuropharmacology. vol 33. issue 3-4. 1994-12-30. PMID:7984271. |
the influence of cocaine exposure on serotonergic neurons and postsynaptic 5-ht1a receptor-mediated responses was evaluated by measuring neuroendocrine responses to a serotonin (5-ht) releaser or a 5-ht1a agonist. |
1994-12-30 |
2023-08-12 |
human |
| S B Park, J T Coull, R H McShane, A H Young, B J Sahakian, T W Robbins, P J Cowe. Tryptophan depletion in normal volunteers produces selective impairments in learning and memory. Neuropharmacology. vol 33. issue 3-4. 1994-12-30. PMID:7984295. |
the amino-acid l-tryptophan is essential in the synthesis of brain serotonin, and its depletion can lead to a widespread reduction in central serotonergic activity. |
1994-12-30 |
2023-08-12 |
human |
| R Numazaw. [Pharmacological characterization of alpha 2-adrenoceptor regulated 5-HT release in the rat hippocampus]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 69. issue 4. 1994-12-28. PMID:7959600. |
these findings suggest that 5-ht release is functionally modulated via alpha 2-adrenoceptors located on the serotonergic nerve terminals in the rat hippocampus. |
1994-12-28 |
2023-08-12 |
rat |
| O Hornykiewicz, K Shanna. Brain monoamines in progressive supranuclear palsy--comparison with idiopathic Parkinson's disease. Journal of neural transmission. Supplementum. vol 42. 1994-12-22. PMID:7964689. |
in contrast to ipd, in patients with psp the serotonin (5-ht) levels in the basal ganglia are not significantly reduced, thus resulting in a relative predominance of the inhibitory serotonergic influences on the motor behaviour in these patients. |
1994-12-22 |
2023-08-12 |
Not clear |
| B P Skop, J A Finkelstein, T R Mareth, M R Magoon, T M Brow. The serotonin syndrome associated with paroxetine, an over-the-counter cold remedy, and vascular disease. The American journal of emergency medicine. vol 12. issue 6. 1994-12-20. PMID:7945606. |
however, a syndrome of excessive serotonergic activity, the "serotonin syndrome" (ss), has recently been recognized. |
1994-12-20 |
2023-08-12 |
Not clear |