| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Bloomquist, E King, A Wright, C Mytilineou, K Kimura, K Castagnoli, N Castagnol. 1-Methyl-4-phenylpyridinium-like neurotoxicity of a pyridinium metabolite derived from haloperidol: cell culture and neurotransmitter uptake studies. The Journal of pharmacology and experimental therapeutics. vol 270. issue 2. 1994-09-28. PMID:8071874. |
this article reports that hpp+ also is toxic to dopaminergic and serotonergic neurons in cultures of embryonic mesencephalic cells, as measured by loss of the ability of exposed cells to accumulate tritium-labeled dopamine and serotonin and by immunochemical staining techniques. |
1994-09-28 |
2023-08-12 |
mouse |
| G Torres, C Rivie. Induction of c-fos in rat brain by acute cocaine and fenfluramine exposure: a comparison study. Brain research. vol 647. issue 1. 1994-09-26. PMID:8069690. |
although cocaine shares the ability of fenfluramine to inhibit the synaptic reuptake of serotonin, previous observations from our group suggest that the genomic effects of fenfluramine in the rat striatum are primarily mediated by dopaminergic rather than serotonergic mechanisms. |
1994-09-26 |
2023-08-12 |
rat |
| H G Series, M E Mollive. Immunocytochemical evidence for serotonergic neurotoxicity of N-ethyl-methylenedioxyamphetamine (MDE). Experimental neurology. vol 128. issue 1. 1994-09-23. PMID:8070524. |
n-ethyl-3,4-methylenedioxyamphetamine (mde) is one of a group of substituted amphetamines which have effects on several serotonergic markers such as tissue levels of serotonin and activity of tryptophan hydroxylase. |
1994-09-23 |
2023-08-12 |
rat |
| L Kubin, C Reignier, H Tojima, O Taguchi, A I Pack, R O Davie. Changes in serotonin level in the hypoglossal nucleus region during carbachol-induced atonia. Brain research. vol 645. issue 1-2. 1994-09-21. PMID:7520343. |
based on our earlier studies in decerebrate cats using injections of carbachol into the pons to induce a rem sleep-like atonia and microinjections of serotonin (5ht) into the xii motor nucleus, we hypothesized that a sleep-related withdrawal of the serotonergic excitatory input to xii motoneurons may play a major role in these processes. |
1994-09-21 |
2023-08-12 |
Not clear |
| L Kubin, C Reignier, H Tojima, O Taguchi, A I Pack, R O Davie. Changes in serotonin level in the hypoglossal nucleus region during carbachol-induced atonia. Brain research. vol 645. issue 1-2. 1994-09-21. PMID:7520343. |
the levels of 5ht and its metabolite, 5-hydroxyindoleacetic acid (5hiaa), were determined using hplc and electrochemical detection in dialysate samples collected over successive 20 min periods under four successive experimental conditions: control (at least 2 h after probe insertion); during the postural atonia and respiratory depression produced by pontine microinjection of carbachol; recovery from the effects of carbachol produced by pontine microinjection of atropine; and, to verify that the presence of 5ht in the dialysate was related to the activity of serotonergic cells of the brainstem, following administration of 8-oh-dpat, a 5ht 1a receptor agonist known to suppress activity in the serotonergic cells of the raphe system. |
1994-09-21 |
2023-08-12 |
Not clear |
| R Sandy. Aggressive behavior in schizophrenia: relationship to age of onset and cortical atrophy. The International journal of neuroscience. vol 68. issue 1-2. 1994-09-19. PMID:8063505. |
specifically, since aggressive behavior has been linked to impairment of serotonergic (5-ht) functions, i propose that the timing of onset of schizophrenia may be partly associated with dysregulation of the 5-ht system. |
1994-09-19 |
2023-08-12 |
crow |
| A V Ravindran, J Chudzik, R J Bialik, Y D Lapierre, P D Hrdin. Platelet serotonin measures in primary dysthymia. The American journal of psychiatry. vol 151. issue 9. 1994-09-16. PMID:8067494. |
serotonergic function in 22 patients with primary dysthymia and 22 normal volunteers was evaluated by measuring [3h]serotonin uptake and [3h]paroxetine binding in platelets. |
1994-09-16 |
2023-08-12 |
human |
| A V Ravindran, J Chudzik, R J Bialik, Y D Lapierre, P D Hrdin. Platelet serotonin measures in primary dysthymia. The American journal of psychiatry. vol 151. issue 9. 1994-09-16. PMID:8067494. |
a significantly lower maximum rate of serotonin uptake was noted in the dysthymic patients than in the normal subjects, indicating a possible serotonergic dysfunction in dysthymia. |
1994-09-16 |
2023-08-12 |
human |
| J L Ridet, H Tamir, A Priva. Direct immunocytochemical localization of 5-hydroxytryptamine receptors in the adult rat spinal cord: a light and electron microscopic study using an anti-idiotypic antiserum. Journal of neuroscience research. vol 38. issue 1. 1994-09-15. PMID:8057387. |
in the present study, we performed the immunodetection of serotonergic (5-ht) receptor subtypes in the spinal cord by using an anti-idiotypic antiserum (th8) at light and electron microscopic levels. |
1994-09-15 |
2023-08-12 |
rat |
| D H Overstreet, D S Janowsky, O Pucilowski, A H Rezvan. Swim test immobility co-segregates with serotonergic but not cholinergic sensitivity in cross-breeds of Flinders Line rats. Psychiatric genetics. vol 4. issue 2. 1994-09-13. PMID:8055248. |
serotonergic sensitivity was assessed as the hypothermic response to 8-oh-dpat, a serotonin (5-ht)-1a agonist, in 35-40 day old rats. |
1994-09-13 |
2023-08-12 |
rat |
| G Bonanno, A Fassio, P Severi, A Ruelle, M Raiter. Fenfluramine releases serotonin from human brain nerve endings by a dual mechanism. Journal of neurochemistry. vol 63. issue 3. 1994-09-08. PMID:8051559. |
it is suggested that, at relatively high concentrations, d-fenfluramine largely diffuses into serotonergic terminals and causes release of 5-ht through the 5-ht carrier working in the inside-outside direction; at relatively low concentrations d-fenfluramine enters the terminals through the 5-ht transporter but elicits release of 5-ht by an exocytotic-like mechanism. |
1994-09-08 |
2023-08-12 |
human |
| S Ferré, R Cortés, F Artiga. Dopaminergic regulation of the serotonergic raphe-striatal pathway: microdialysis studies in freely moving rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 8. 1994-08-30. PMID:7519257. |
given the existence of somatodendritic 5-ht1a autoreceptors in the drn, changes of the extracellular concentration of 5-ht in the vicinity of cell bodies and dendrites may be relevant for the control of the activity of ascending serotonergic pathways. |
1994-08-30 |
2023-08-12 |
rat |
| T M Cabrera, A D Levy, Q Li, L D Van de Kar, G Battagli. Cocaine-induced deficits in ACTH and corticosterone responses in female rat progeny. Brain research bulletin. vol 34. issue 2. 1994-08-30. PMID:8044692. |
central serotonergic function was determined by the ability of a serotonin releaser, p-chloroamphetamine (pca), to stimulate plasma adrenocorticotropin (acth), corticosterone, and renin secretion in female progeny at postnatal day (pd) 30. |
1994-08-30 |
2023-08-12 |
rat |
| J G Hensler, R C Ferry, D M Labow, G B Kovachich, A Fraze. Quantitative autoradiography of the serotonin transporter to assess the distribution of serotonergic projections from the dorsal raphe nucleus. Synapse (New York, N.Y.). vol 17. issue 1. 1994-08-23. PMID:8042142. |
quantitative autoradiography of the serotonin transporter to assess the distribution of serotonergic projections from the dorsal raphe nucleus. |
1994-08-23 |
2023-08-12 |
rat |
| J G Hensler, R C Ferry, D M Labow, G B Kovachich, A Fraze. Quantitative autoradiography of the serotonin transporter to assess the distribution of serotonergic projections from the dorsal raphe nucleus. Synapse (New York, N.Y.). vol 17. issue 1. 1994-08-23. PMID:8042142. |
the binding of 3h-cn-imi to 5-ht uptake sites, as measured by quantitative autoradiography, was used as a marker of serotonergic neurons. |
1994-08-23 |
2023-08-12 |
rat |
| J G Hensler, R C Ferry, D M Labow, G B Kovachich, A Fraze. Quantitative autoradiography of the serotonin transporter to assess the distribution of serotonergic projections from the dorsal raphe nucleus. Synapse (New York, N.Y.). vol 17. issue 1. 1994-08-23. PMID:8042142. |
the heterogeneous pattern of binding of these two radioligands within the dorsal raphe nucleus was similar and corresponded to the distribution of serotonergic cell bodies as visualized by 5-ht immunohistochemistry. |
1994-08-23 |
2023-08-12 |
rat |
| J G Hensler, R C Ferry, D M Labow, G B Kovachich, A Fraze. Quantitative autoradiography of the serotonin transporter to assess the distribution of serotonergic projections from the dorsal raphe nucleus. Synapse (New York, N.Y.). vol 17. issue 1. 1994-08-23. PMID:8042142. |
pca treatment appeared to produce a moderate loss of serotonergic innervation in serotonergic terminal field areas as visualized by serotonin immunohistochemistry. |
1994-08-23 |
2023-08-12 |
rat |
| A C Linthorst, C Flachskamm, F Holsboer, J M Reu. Local administration of recombinant human interleukin-1 beta in the rat hippocampus increases serotonergic neurotransmission, hypothalamic-pituitary-adrenocortical axis activity, and body temperature. Endocrinology. vol 135. issue 2. 1994-08-18. PMID:7518383. |
perfusion of the probes was conducted with a ringer's solution containing 0.1 or 1.0 microm hil-1 beta or without hil-1 beta, usually for 6 h. time-dependent changes in serotonergic neurotransmission and hypothalamic-pituitary-adrenocortical activity were simultaneously monitored by measuring serotonin [5-hydroxytryptamine (5-ht)], 5-hydroxyindoleacetic acid, and corticosterone concentrations in the dialysates. |
1994-08-18 |
2023-08-12 |
human |
| A Singh, P Redfer. Lack of circadian variation in the responsiveness of alpha 2-heteroreceptors regulating serotonin release. Chronobiology international. vol 11. issue 2. 1994-08-16. PMID:7518357. |
however, recently identified alpha 2-adrenoceptors located on 5-ht nerve terminals may be important in regulating the release of 5-ht from serotonergic neurons. |
1994-08-16 |
2023-08-12 |
rat |
| D C Merz, P Drapea. Segmental specificity of neuronal recognition during synapse formation between identified leech neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 7. 1994-08-11. PMID:8027766. |
an early event in the formation of inhibitory synapses between the serotonergic retzius (r) neuron and the pressure-sensitive (p) neuron of the leech is the elimination of an extrasynaptic, depolarizing response to 5-ht in the p cell from sites of contact. |
1994-08-11 |
2023-08-12 |
Not clear |