| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S B Potrebic, P Mason, H L Field. The density and distribution of serotonergic appositions onto identified neurons in the rat rostral ventromedial medulla. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 5 Pt 1. 1995-06-20. PMID:7751910. |
the rvm contains serotonergic terminal arbors, serotonergic neurons and several types of serotonin (5-ht) receptors. |
1995-06-20 |
2023-08-12 |
rat |
| S B Potrebic, P Mason, H L Field. The density and distribution of serotonergic appositions onto identified neurons in the rat rostral ventromedial medulla. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 5 Pt 1. 1995-06-20. PMID:7751910. |
five off, five on, and three serotonergic neutral cells were examined with the confocal microscope for appositions between 5-ht immunoreactive (5-ht-ir) processes and intracellularly labeled processes. |
1995-06-20 |
2023-08-12 |
rat |
| S B Potrebic, P Mason, H L Field. The density and distribution of serotonergic appositions onto identified neurons in the rat rostral ventromedial medulla. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 5 Pt 1. 1995-06-20. PMID:7751910. |
because the rvm has several sources of serotonergic input and a number of different 5-ht receptor subtypes, further understanding of the role of rvm 5-ht afferents will require pharmacological studies to determine the action of 5-ht on each cell class and anatomical studies to determine the brainstem origin of serotonergic input to each cell class. |
1995-06-20 |
2023-08-12 |
rat |
| J E Sprague, D E Nichol. The monoamine oxidase-B inhibitor L-deprenyl protects against 3,4-methylenedioxymethamphetamine-induced lipid peroxidation and long-term serotonergic deficits. The Journal of pharmacology and experimental therapeutics. vol 273. issue 2. 1995-06-19. PMID:7538579. |
3,4-methylenedioxymethamphetamine (mdma)-induced serotonergic neurotoxicity was assessed in the striatum, hippocampus and frontal cortex of rats by using [3h]paroxetine binding to label serotonin (5-ht) uptake sites and 5-ht and 5-hydroxyindoleacetic acid (5-hiaa) levels as markers of serotonergic function. |
1995-06-19 |
2023-08-12 |
rat |
| J L Ram, K Judge, M A Jedna. Antagonists of cholinergic and serotonergic responses of Aplysia buccal muscle. Comparative biochemistry and physiology. Pharmacology, toxicology and endocrinology. vol 107. issue 2. 1995-06-16. PMID:7749591. |
cholinergic and serotonergic receptors of aplysia californica buccal muscles were characterized pharmacologically by determining compounds that effectively inhibited contractile responses to acetylcholine (ach) and modulatory effects of serotonin (5-ht), respectively. |
1995-06-16 |
2023-08-12 |
aplysia |
| S M K. Pharmacotherapy of obsessive-compulsive disorder. The British journal of clinical practice. vol 49. issue 1. 1995-06-15. PMID:7742183. |
this is largely due to the development of the serotonergic group of antidepressants, the selective serotonin reuptake inhibitors (ssris), which have consistently demonstrated antiobsessional properties. |
1995-06-15 |
2023-08-12 |
Not clear |
| A L Killam, S W Watts, M L Cohe. Role of alpha 1-adrenoceptors and 5-HT2 receptors in serotonin-induced contraction of rat prostate: autoradiographical and functional studies. European journal of pharmacology. vol 273. issue 1-2. 1995-06-05. PMID:7737320. |
these studies compared adrenergic and serotonergic functional activity to specific alpha 1 and serotonin (5-hydroxytryptamine; 5-ht) binding sites in the rat prostate. |
1995-06-05 |
2023-08-12 |
rat |
| P J Wellman, S Tow, L McMaho. Isobolographic assessment of the effects of combinations of phenylpropanolamine and fenfluramine on food intake in rats. Pharmacology, biochemistry, and behavior. vol 50. issue 2. 1995-06-02. PMID:7740069. |
the serotonergic (5-ht) agonist fenfluramine (fen) is thought to suppress appetite via stimulation of 5-ht release within the pvn rather than activation of adrenergic receptors. |
1995-06-02 |
2023-08-12 |
rat |
| F Datiche, P H Luppi, M Cattarell. Serotonergic and non-serotonergic projections from the raphe nuclei to the piriform cortex in the rat: a cholera toxin B subunit (CTb) and 5-HT immunohistochemical study. Brain research. vol 671. issue 1. 1995-06-01. PMID:7537163. |
serotonergic and non-serotonergic projections from the raphe nuclei to the piriform cortex in the rat: a cholera toxin b subunit (ctb) and 5-ht immunohistochemical study. |
1995-06-01 |
2023-08-12 |
rat |
| F Datiche, P H Luppi, M Cattarell. Serotonergic and non-serotonergic projections from the raphe nuclei to the piriform cortex in the rat: a cholera toxin B subunit (CTb) and 5-HT immunohistochemical study. Brain research. vol 671. issue 1. 1995-06-01. PMID:7537163. |
retrograde axonal transport of the cholera toxin b subunit (ctb) was combined with 5-ht immunohistochemistry to determine the origin of the serotonergic innervation of the piriform cortex (pc) in the rat. |
1995-06-01 |
2023-08-12 |
rat |
| W T Carpente. Serotonin-dopamine antagonists and treatment of negative symptoms. Journal of clinical psychopharmacology. vol 15. issue 1 Suppl 1. 1995-05-31. PMID:7730498. |
a number of clinical trials provide data on the effect of adding serotonergic drugs to conventional neuroleptics in the treatment of schizophrenia, and there are now studies with drugs that combine serotonin and dopamine antagonism in the same molecule. |
1995-05-31 |
2023-08-12 |
Not clear |
| H Fuder, P Ries, P Schwar. Histamine and serotonin released from the rat perfused heart by compound 48/80 or by allergen challenge influence noradrenaline or acetylcholine exocytotic release. Fundamental & clinical pharmacology. vol 8. issue 6. 1995-05-25. PMID:7536702. |
in conclusion, degranulation of immunological cells is followed by histamine and serotonin release in the rat heart and may affect the release of autonomic neurotransmitters in rather unusual ways, by i) an uptake1-dependent and ii) an h2-mediated facilitation which probably involves nitric oxide as a permissive mediator, and iii) a serotonergic inhibition, of noradrenaline release, and iv) an h3- and serotonergic facilitation of acetylcholine release. |
1995-05-25 |
2023-08-12 |
rat |
| F C Zhou, E C Azmitia, S Bledso. Rapid serotonergic fiber sprouting in response to ibotenic acid lesion in the striatum and hippocampus. Brain research. Developmental brain research. vol 84. issue 1. 1995-05-25. PMID:7720221. |
serotonergic (5-ht) sprouting occurs after damage of neighboring 5-ht or non-5-ht fibers. |
1995-05-25 |
2023-08-12 |
Not clear |
| H Kabuto, I Yokoi, K Iwaya, A Mor. Monoamine release in the rat striatum is induced by delta-guanidinovaleric acid and inhibited by GABA agonists. Life sciences. vol 56. issue 20. 1995-05-25. PMID:7723603. |
these results suggest that the activation of gaba receptors inhibits the release of da and 5-ht in the striatum, and that the dopaminergic system regulates gaba-b receptors and the serotonergic system mainly regulates gaba-a receptors. |
1995-05-25 |
2023-08-12 |
rat |
| M B Stein, S M Delaney, M J Chartier, C D Kroft, A L Haze. [3H]paroxetine binding to platelets of patients with social phobia: comparison to patients with panic disorder and healthy volunteers. Biological psychiatry. vol 37. issue 4. 1995-05-18. PMID:7711158. |
to the extent that the serotonin transporter in platelets and neurons is comparable, these findings suggest that this aspect of serotonergic function is normal in patients with social phobia. |
1995-05-18 |
2023-08-12 |
human |
| R Schreiber, M Brocco, V Audinot, A Gobert, S Veiga, M J Milla. (1-(2,5-dimethoxy-4 iodophenyl)-2-aminopropane)-induced head-twitches in the rat are mediated by 5-hydroxytryptamine (5-HT) 2A receptors: modulation by novel 5-HT2A/2C antagonists, D1 antagonists and 5-HT1A agonists. The Journal of pharmacology and experimental therapeutics. vol 273. issue 1. 1995-05-17. PMID:7714755. |
in this study, the involvement of serotonergic and dopaminergic receptors in the modulation of the head-twitch (htw) response to the 5-hydroxytryptamine (5-ht)2a/5-ht2c agonist, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane, was characterized in rats using novel and selective ligands at 5-ht2a, 5-ht2c, d1, d2 and 5-ht1a receptors. |
1995-05-17 |
2023-08-12 |
rat |
| M L Silverthorn, C M Dersch, M H Baumann, J L Cadet, J S Partilla, K C Rice, F I Carroll, K M Becketts, A Brockington, R B Rothma. Studies of the biogenic amine transporters. V. Demonstration of two binding sites for the cocaine analog [125I]RTI-55 associated with the 5-HT transporter in rat brain membranes. The Journal of pharmacology and experimental therapeutics. vol 273. issue 1. 1995-05-17. PMID:7714769. |
selective lesioning of dopaminergic and serotonergic neurons with intracerebroventricular 6-hydroxydopamine and 5,7-dihydroxytryptamine selectively decreased [125i]rti-55 binding to da and 5-ht transporters, respectively, thereby confirming the selectivity of the assay conditions. |
1995-05-17 |
2023-08-12 |
rat |
| M A Klitenick, D Wirtshafte. Behavioral and neurochemical effects of opioids in the paramedian midbrain tegmentum including the median raphe nucleus and ventral tegmental area. The Journal of pharmacology and experimental therapeutics. vol 273. issue 1. 1995-05-17. PMID:7714785. |
the induction of hyperactivity by dpdpe and damgo was unaltered in animals with large depletions of forebrain serotonin produced by injections of 5,7-dihydroxytryptamine, suggesting that these effects were not mediated through serotonergic mechanisms. |
1995-05-17 |
2023-08-12 |
rat |
| C L Tsai, T H Jang, L H Wan. Effects of mercury on serotonin concentration in the brain of tilapia, Oreochromis mossambicus. Neuroscience letters. vol 184. issue 3. 1995-05-17. PMID:7715848. |
in order to know the effect of mercury pollution on the serotonergic system of fish, serotonin concentrations in a discrete brain region of tilapia, oreochromis mossambicus, were examined. |
1995-05-17 |
2023-08-12 |
Not clear |
| P D Penev, F W Turek, P C Ze. A serotonin neurotoxin attenuates the phase-shifting effects of triazolam on the circadian clock in hamsters. Brain research. vol 669. issue 2. 1995-05-15. PMID:7712176. |
the finding that a 5-ht neurotoxin can attenuate the phase-shifting effects of triazolam in hamsters, without interfering with its activity-inducing properties, suggests that serotonergic afferents might be involved in the mechanism for non-photic phase-shifting of the circadian system. |
1995-05-15 |
2023-08-12 |
Not clear |