| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D J Nutt, S J Wilson, N J Couplan. Use of selective serotonin reuptake inhibitors and other serotonergic drugs in the biological dissection of affective disorders. International clinical psychopharmacology. vol 9 Suppl 4. 1995-08-31. PMID:7622825. |
more recently, the role of selective serotonin reuptake inhibitors (ssris) and other serotonergic drugs in sleep, and in the control of cardiovascular homeostasis, has been studied. |
1995-08-31 |
2023-08-12 |
Not clear |
| D Schmitz, R M Empson, T Gloveli, U Heineman. Serotonin reduces synaptic excitation of principal cells in the superficial layers of rat hippocampal-entorhinal cortex combined slices. Neuroscience letters. vol 190. issue 1. 1995-08-31. PMID:7624050. |
the cells of the entorhinal cortex receive a dense innervation of serotonergic fibres from the raphe nuclei and express a high density of 5-hydroxytryptamine 1a (5-ht1a) receptors. |
1995-08-31 |
2023-08-12 |
rat |
| W Boye. Serotonin uptake inhibitors are superior to imipramine and alprazolam in alleviating panic attacks: a meta-analysis. International clinical psychopharmacology. vol 10. issue 1. 1995-08-30. PMID:7622804. |
these findings underscore the importance of serotonin reuptake inhibitors in the treatment of panic disorder and indirectly add to the evidence that serotonergic abnormalities may have a role in its etiology. |
1995-08-30 |
2023-08-12 |
Not clear |
| J Labrecque, A Fargin, M Bouvier, P Chidiac, M Denni. Serotonergic antagonists differentially inhibit spontaneous activity and decrease ligand binding capacity of the rat 5-hydroxytryptamine type 2C receptor in Sf9 cells. Molecular pharmacology. vol 48. issue 1. 1995-08-30. PMID:7623769. |
serotonergic antagonists differentially inhibit spontaneous activity and decrease ligand binding capacity of the rat 5-hydroxytryptamine type 2c receptor in sf9 cells. |
1995-08-30 |
2023-08-12 |
rat |
| J Labrecque, A Fargin, M Bouvier, P Chidiac, M Denni. Serotonergic antagonists differentially inhibit spontaneous activity and decrease ligand binding capacity of the rat 5-hydroxytryptamine type 2C receptor in Sf9 cells. Molecular pharmacology. vol 48. issue 1. 1995-08-30. PMID:7623769. |
the activities of serotonergic antagonists as inverse agonists at the rat 5-hydroxytryptamine (5-ht)2c serotonin receptor were compared with their potencies in promoting receptor "down-regulation," after expression of the recombinant receptor in the baculovirus/sf9 insect cell system. |
1995-08-30 |
2023-08-12 |
rat |
| D Marazziti, S Presta, S Silvestri, A Battistini, L Mosti, C Balestri, L Palego, L Cont. Platelet markers in suicide attempters. Progress in neuro-psychopharmacology & biological psychiatry. vol 19. issue 3. 1995-08-28. PMID:7624489. |
the reduced 3h-imi binding and 5ht uptake may be related to a hypofunction of presynaptic serotonergic mechanisms which might be altered in suicidal behavior. |
1995-08-28 |
2023-08-12 |
Not clear |
| R R Matsumoto, N Aziz, D D Truon. Association between brain indole levels and severity of posthypoxic myoclonus in rats. Pharmacology, biochemistry, and behavior. vol 50. issue 4. 1995-08-24. PMID:7542390. |
in the present study, the levels of 5-htp, 5-ht, and 5-hiaa were measured in seven regions of the brain in myoclonic and normal rats to identify the areas of the brain in which a serotonergic dysfunction resides. |
1995-08-24 |
2023-08-12 |
rat |
| J Zoldan, G Friedberg, M Livneh, E Melame. Psychosis in advanced Parkinson's disease: treatment with ondansetron, a 5-HT3 receptor antagonist. Neurology. vol 45. issue 7. 1995-08-24. PMID:7617188. |
the psychosis may be due, in part, to overstimulation of central serotonergic (5-ht) receptors. |
1995-08-24 |
2023-08-12 |
Not clear |
| J Zoldan, G Friedberg, M Livneh, E Melame. Psychosis in advanced Parkinson's disease: treatment with ondansetron, a 5-HT3 receptor antagonist. Neurology. vol 45. issue 7. 1995-08-24. PMID:7617188. |
our study suggests that pharmacologic blockade of central 5-ht receptors may become a strategy to attenuate pd psychosis without inducing motor deterioration or suppression of antiparkinsonian action of levodopa, and it lends support to the hypothesis that serotonergic mechanisms are pathogenetically important in the emergence of psychosis in pd. |
1995-08-24 |
2023-08-12 |
Not clear |
| W B West, B J Van Groll, J B Appe. Stimulus effects of d-amphetamine II: DA, NE, and 5-HT mechanisms. Pharmacology, biochemistry, and behavior. vol 51. issue 1. 1995-08-22. PMID:7617735. |
therefore, rats were trained to discriminate d-amphetamine (1 mg/kg) from saline and given combination (antagonism, potentiation) or substitution (generalization) tests with drugs that act through da, noradrenergic, or serotonergic (5-ht) mechanisms. |
1995-08-22 |
2023-08-12 |
rat |
| G Muñoz-Acedo, I Alvaro-Alonso, E Arill. Pancreatic changes in somatostatin content and receptor/effector system after intrapancreatic injection of 5,7-dihydroxytryptamine. The Journal of endocrinology. vol 145. issue 2. 1995-08-18. PMID:7616156. |
in this study, the intrapancreatic serotonergic nerves were chemically ablated by injecting a specific serotonin (5-ht) neurotoxin, 5,7-dihydroxytryptamine (5,7-dht), into the substance of the gland. |
1995-08-18 |
2023-08-12 |
rat |
| R B Rothman, M L Silverthorn, M H Baumann, C B Goodman, J L Cadet, D Matecka, K C Rice, F I Carroll, J B Wang, G R Uh. Studies of the biogenic amine transporters. VI. Characterization of a novel cocaine binding site, identified with [125I]RTI-55, in membranes prepared from whole rat brain minus caudate. The Journal of pharmacology and experimental therapeutics. vol 274. issue 1. 1995-08-18. PMID:7616423. |
previous studies showed that the cocaine analog [125i]rti-55 labels dopamine and serotonergic (5-ht) biogenic amine transporters (bats) with high affinity. |
1995-08-18 |
2023-08-12 |
rat |
| N Wiernsperge. Serotonin 5-HT2 receptors and brain circulation. Journal of cardiovascular pharmacology. vol 16 Suppl 3. 1995-08-17. PMID:1369712. |
in ischemia, platelet invasion, rupture of the blood-brain barrier, liberation of 5-ht from nerve terminals inside the vessel wall, and necrosis of serotonergic neurons favor local increases of the transmitter in the brain. |
1995-08-17 |
2023-08-11 |
Not clear |
| N Wiernsperge. Serotonin 5-HT2 receptors and brain circulation. Journal of cardiovascular pharmacology. vol 16 Suppl 3. 1995-08-17. PMID:1369712. |
5-ht2 receptors appear to be the major effector of these actions of serotonin, judging from experimental and clinical pharmacology data with specific or partial 5-ht2 serotonergic antagonists. |
1995-08-17 |
2023-08-11 |
Not clear |
| L Drouet, C Bal Dit Sollier, S Ruton, G Pignau. Role of serotonin in arteriolar thrombosis and secondary vasospasm. Journal of cardiovascular pharmacology. vol 16 Suppl 3. 1995-08-17. PMID:1369719. |
in this setting, we studied the reactivity of sprague-dawley rats treated with three 5-ht2 serotonergic antagonists (ketanserin, ritanserin, and naftidrofuryl) and that of fawn-hooded rats (a strain affected by a congenital reduction of platelet dense granules, with a resulting decrease in platelet content of serotonin, adp, and catecholamines). |
1995-08-17 |
2023-08-11 |
rat |
| J A Stamp, K Semb. Extent of colocalization of serotonin and GABA in the neurons of the rat raphe nuclei. Brain research. vol 677. issue 1. 1995-08-17. PMID:7606468. |
all the nine serotonergic cell groups known to be present in the brainstem were examined with an indirect immunofluorescence method using antibodies against serotonin and glutamic acid decarboxylase in colchicine-treated rats. |
1995-08-17 |
2023-08-12 |
rat |
| C F Phelix, P A Broderic. Light microscopic immunocytochemical evidence of converging serotonin and dopamine terminals in ventrolateral nucleus accumbens. Brain research bulletin. vol 37. issue 1. 1995-08-15. PMID:7606477. |
these monoaminergic neurons consist of the serotonergic (5-ht) neurons of the dorsal and median raphe and the dopaminergic (da) neurons of the ventral tegmental area (vta). |
1995-08-15 |
2023-08-12 |
rat |
| H Okamura, F Kawakami, Y Tamada, M Geffard, T Nishiwaki, Y Ibata, S T Inouy. Circadian change of VIP mRNA in the rat suprachiasmatic nucleus following p-chlorophenylalanine (PCPA) treatment in constant darkness. Brain research. Molecular brain research. vol 29. issue 2. 1995-08-15. PMID:7609623. |
neuronal activity of the suprachiasmatic nucleus (scn) is known to be regulated by two major extrinsic factors conveyed by three anatomically distinct pathways to the scn: photic stimulus by the direct retinohypothalamic tract (rht) and the indirect geniculohypothalamic tract (ght), and information from the brainstem by ascending forebrain serotonergic (5-hydroxytryptamine: 5-ht) tract. |
1995-08-15 |
2023-08-12 |
rat |
| D W Hudgel, E A Gordon, H Y Meltze. Abnormal serotonergic stimulation of cortisol production in obstructive sleep apnea. American journal of respiratory and critical care medicine. vol 152. issue 1. 1995-08-10. PMID:7599822. |
because serotonin (5-ht) precursor or reuptake inhibitors improve obstructive sleep apnea (osa), we hypothesized that brain serotonergic activity may be decreased in osa. |
1995-08-10 |
2023-08-12 |
human |
| C Spenger, C Hyman, L Studer, M Egli, L Evtouchenko, C Jackson, A Dahl-Jørgensen, R M Lindsay, R W Seile. Effects of BDNF on dopaminergic, serotonergic, and GABAergic neurons in cultures of human fetal ventral mesencephalon. Experimental neurology. vol 133. issue 1. 1995-08-10. PMID:7601263. |
the presence of gabaergic and serotonergic neurons in this culture system was confirmed by gaba and 5-ht immunocytochemistry. |
1995-08-10 |
2023-08-12 |
human |