| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T A Slotkin, G A Barnes, E C McCook, F J Seidle. Programming of brainstem serotonin transporter development by prenatal glucocorticoids. Brain research. Developmental brain research. vol 93. issue 1-2. 1996-11-29. PMID:8804702. |
there were no comparable effects on serotonin transmitter levels, indicating selectivity toward promotion of transporter expression as distinct from simply increasing the number of serotonergic nerve terminals or all nerve terminal components. |
1996-11-29 |
2023-08-12 |
rat |
| K R Bonson, J W Buckholtz, D L Murph. Chronic administration of serotonergic antidepressants attenuates the subjective effects of LSD in humans. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 14. issue 6. 1996-11-27. PMID:8726753. |
possible mechanisms of action for the effects from serotonergic antidepressants involve 5-ht2 and 5-ht1a receptors, changes in extracellular brain serotonin concentrations, and changes in brain catecholamine systems. |
1996-11-27 |
2023-08-12 |
human |
| J C Bizot, M H Thiébo. Impulsivity as a confounding factor in certain animal tests of cognitive function. Brain research. Cognitive brain research. vol 3. issue 3-4. 1996-11-27. PMID:8806026. |
impulsive-like behaviour may be modified by serotonergic (5-ht) activity, with underactivity in 5-ht neurotransmission increasing impulsivity and vice versa. |
1996-11-27 |
2023-08-12 |
human |
| J L Russel. Relatively low doses of cisapride in the treatment of nausea in patients treated with venlafaxine for treatment-refractory depression. Journal of clinical psychopharmacology. vol 16. issue 1. 1996-11-27. PMID:8834416. |
this further suggests that the nausea associated with serotonergic reuptake inhibition may be a result of 5-hydroxytryptamine (5-ht3) agonist action. |
1996-11-27 |
2023-08-12 |
Not clear |
| R W Fulle. Fluoxetine effects on serotonin function and aggressive behavior. Annals of the New York Academy of Sciences. vol 794. 1996-11-27. PMID:8853595. |
the enhanced serotonergic neurotransmission resulting from increased action of that extracellular serotonin on postsynaptic receptors on target neurons results in various functional changes, reflecting the wide distribution of serotonin nerve terminals in brain regions that regulate numerous physiological functions. |
1996-11-27 |
2023-08-12 |
Not clear |
| R S Liem, J C Copra. Immunogold localization of serotonin within synaptic terminals in the rat mesencephalic trigeminal nucleus. Acta anatomica. vol 155. issue 1. 1996-11-26. PMID:8811115. |
with the use of postembedding electron-microscopic immunogold cytochemistry, the vesicular distribution of serotonin within serotonergic synaptic terminals in the mesencephalic trigeminal nucleus was determined in order to obtain further insight into the mechanisms and functional significance of serotonin release to these jaw muscle spindle afferent neurons. |
1996-11-26 |
2023-08-12 |
rat |
| R S Liem, J C Copra. Immunogold localization of serotonin within synaptic terminals in the rat mesencephalic trigeminal nucleus. Acta anatomica. vol 155. issue 1. 1996-11-26. PMID:8811115. |
these synaptic terminals may represent highly active serotonergic synapses with a high release frequency and a high reuptake level, resulting in a dense concentration of vesicles containing a high amount of serotonin near the synaptic cleft. |
1996-11-26 |
2023-08-12 |
rat |
| Y Charnay, L Léger, P G Vallet, B Greggio, P R Hof, M Jouvet, C Boura. Mapping of serotonin transporter messenger RNA-containing nerve cell populations in the cat brainstem. Journal of chemical neuroanatomy. vol 10. issue 2. 1996-11-20. PMID:8783039. |
overall, these data agree with the notion that in the cat, as previously suggested in the human and in the rat brain, the serotonin membrane transporter messenger rna is predominantly expressed in areas known to contain serotonergic cell bodies. |
1996-11-20 |
2023-08-12 |
human |
| Y Takada, T Urano, J Malyszko, A Takad. Changes in serotonergic measures in whole blood and various brain regions of rats administered with the 5-HT1A agonist tandospirone and/or exposed to electric foot-shock. Brain research bulletin. vol 40. issue 1. 1996-11-18. PMID:8722753. |
the administration of tandospirone did not result in changes in serotonergic measures, but stress or stress plus the administration of tandospirone resulted in an increase in blood levels of tryptophan, 5-ht, and 5-hiaa. |
1996-11-18 |
2023-08-12 |
rat |
| Y Takada, T Urano, J Malyszko, A Takad. Changes in serotonergic measures in whole blood and various brain regions of rats administered with the 5-HT1A agonist tandospirone and/or exposed to electric foot-shock. Brain research bulletin. vol 40. issue 1. 1996-11-18. PMID:8722753. |
these results suggest that tandospirone may stimulate presynaptic receptors in the midbrain and inhibit the activity of monoamine oxidase, resulting in an increase in 5-ht levels in the serotonergic nerve terminals. |
1996-11-18 |
2023-08-12 |
rat |
| E Seifritz, P Baumann, M J Müller, O Annen, M Amey, U Hemmeter, M Hatzinger, F Chardon, E Holsboer-Trachsle. Neuroendocrine effects of a 20-mg citalopram infusion in healthy males. A placebo-controlled evaluation of citalopram as 5-HT function probe. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 14. issue 4. 1996-11-18. PMID:8924193. |
because of citalopram's extremely high selectivity for the presynaptic 5-hydroxytryptamine nerve terminals, the present data suggest that it might be a promising tool for the investigation of serotonergic function in the human brain in vivo. |
1996-11-18 |
2023-08-12 |
human |
| T Hori, T Suzuki, A Baba, S Abe, T Yamamoto, T Moroji, H Shiraish. Effects of phencyclidine metabolites on serotonin uptake in rat brain. Neuroscience letters. vol 209. issue 3. 1996-11-08. PMID:8736633. |
these results suggest that the serotonergic effects of pcp, in part, may be based on the effects of pcp metabolites on 5-ht uptake. |
1996-11-08 |
2023-08-12 |
rat |
| J A Kim, M J Drus. Protective effects of maternal buspirone treatment on serotonin reuptake sites in ethanol-exposed offspring. Brain research. Developmental brain research. vol 92. issue 2. 1996-11-08. PMID:8738126. |
5-ht) could contribute to subsequent developmental abnormalities in serotonergic neurons. |
1996-11-08 |
2023-08-12 |
rat |
| C P Smith, A T Woods-Kettelberger, R Corbett, S M Chesson, G M Bores, W W Petko, J E Roehr, S Kongsamu. Serotonergic activity of HP 184: does spontaneous release have a role? Neurochemical research. vol 21. issue 5. 1996-11-07. PMID:8726966. |
administration of 30 mg/kg hp 184, the ratio of whole brain 5-hydroxyindolacetic acid (5-hiaa) to 5-ht was increased, suggesting serotonergic activation. |
1996-11-07 |
2023-08-12 |
rat |
| C A Toledo, D E Hamassaki-Britto, L R Britt. Serotonergic afferents of the pigeon accessory optic nucleus. Brain research. vol 705. issue 1-2. 1996-11-06. PMID:8821767. |
injections of a retrograde tracer into the accessory optic nucleus of the basal optic root (nbor) of the pigeon, combined with 5-ht immunochemistry, revealed that serotonergic projections to the nbor appeared to originate mainly from the median (mr) and paramedian (pmr) raphe nuclei. |
1996-11-06 |
2023-08-12 |
pigeon |
| J S Rudge, M J Eaton, P Mather, R M Lindsay, S R Whittemor. CNTF induces raphe neuronal precursors to switch from a serotonergic to a cholinergic phenotype in vitro. Molecular and cellular neurosciences. vol 7. issue 3. 1996-11-05. PMID:8726104. |
in this study, cntf and leukemia inhibitory factor (lif) reduced the apparent number of primary serotonergic neurons in e14 raphe culture by 90% as determined by immunocytochemistry for serotonin (5ht). |
1996-11-05 |
2023-08-12 |
mouse |
| J S Rudge, M J Eaton, P Mather, R M Lindsay, S R Whittemor. CNTF induces raphe neuronal precursors to switch from a serotonergic to a cholinergic phenotype in vitro. Molecular and cellular neurosciences. vol 7. issue 3. 1996-11-05. PMID:8726104. |
the reduction in 5ht cell number was not due to neuronal loss as removal of cntf after 4 days in culture resulted in a partial restitution of the serotonergic phenotype. |
1996-11-05 |
2023-08-12 |
mouse |
| J S Rudge, M J Eaton, P Mather, R M Lindsay, S R Whittemor. CNTF induces raphe neuronal precursors to switch from a serotonergic to a cholinergic phenotype in vitro. Molecular and cellular neurosciences. vol 7. issue 3. 1996-11-05. PMID:8726104. |
in the rn46a serotonergic cell line which is induced to become serotonergic by brain-derived neurotrophic factor (bdnf), the addition of cntf suppressed tryptophan hydroxylase and 5ht synthesis and increased choline acetyl transferase (chat) expression by 6-fold and chat activity by 20- to 30-fold over 12 days. |
1996-11-05 |
2023-08-12 |
mouse |
| N Bel, F Artiga. In vivo effects of the simultaneous blockade of serotonin and norepinephrine transporters on serotonergic function. Microdialysis studies. The Journal of pharmacology and experimental therapeutics. vol 278. issue 3. 1996-11-05. PMID:8819487. |
in vivo effects of the simultaneous blockade of serotonin and norepinephrine transporters on serotonergic function. |
1996-11-05 |
2023-08-12 |
rat |
| M Matsumoto, M Yoshioka, H Togashi, T Ikeda, H Sait. Functional regulation by dopamine receptors of serotonin release from the rat hippocampus: in vivo microdialysis study. Naunyn-Schmiedeberg's archives of pharmacology. vol 353. issue 6. 1996-10-29. PMID:8738295. |
these results indicate that the spontaneous 5-ht levels in the rat hippocampus can be used as indices of neuronal origin from the serotonergic nerve terminals. |
1996-10-29 |
2023-08-12 |
rat |