| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L A Mamounas, M E Blue, J A Siuciak, C A Alta. Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 12. 1996-06-06. PMID:8613731. |
the present study examined whether chronic pain parenchymal administration of the neurotrophins brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3) or ngf could prevent the severe degenerative loss of serotonergic axons normally caused by the selective 5-ht neurotoxin p-chloroamphetamine (pca). |
1996-06-06 |
2023-08-12 |
rat |
| L A Mamounas, M E Blue, J A Siuciak, C A Alta. Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 12. 1996-06-06. PMID:8613731. |
in contrast, cortical infusions of vehicle or the control protein cytochrome c did not alter the density of serotonergic axons in intact animals, nor did control infusions prevent the loss of 5-ht axons in pca-treated rats. |
1996-06-06 |
2023-08-12 |
rat |
| L A Mamounas, M E Blue, J A Siuciak, C A Alta. Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 12. 1996-06-06. PMID:8613731. |
thus, bdnf can promote the sprouting of mature, uninjured serotonergic axons and dramatically enhance the survival or sprouting of 5-ht axons normally damaged by the serotonergic neurotoxin pca. |
1996-06-06 |
2023-08-12 |
rat |
| B Olivier, J Mos, R van Oorschot, R He. Serotonin receptors and animal models of aggressive behavior. Pharmacopsychiatry. vol 28 Suppl 2. 1996-06-05. PMID:8614705. |
by and large, male and female rats react similarly to treatment with serotonergic drugs, and this fact underlines the consistent role of 5-ht in different forms of aggression. |
1996-06-05 |
2023-08-12 |
rat |
| A C Bonha. Neurotransmitters in the CNS control of breathing. Respiration physiology. vol 101. issue 3. 1996-05-21. PMID:8606995. |
serotonin has also been implicated in regulating respiratory rhythm, possibly via serotonergic projections originating in the raphe nuclei. |
1996-05-21 |
2023-08-12 |
Not clear |
| P R Wade, J Chen, B Jaffe, I S Kassem, R D Blakely, M D Gersho. Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 7. 1996-05-09. PMID:8601815. |
mucosal epithelial cells thus express a plasmalemmal 5-ht transporter identical to that of serotonergic neurons. |
1996-05-09 |
2023-08-12 |
Not clear |
| P J Schwartz, T A Wehr, N E Rosenthal, J J Bartko, D A Oren, C Luetke, D L Murph. Serotonin and thermoregulation. Physiologic and pharmacologic aspects of control revealed by intravenous m-CPP in normal human subjects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 13. issue 2. 1996-04-25. PMID:8597522. |
meta-chlorophenylpiperazine (m-cpp), a probe of central serotonergic function, elevates core temperature in rodents, nonhuman primates, and humans via serotonin receptor-mediated mechanisms. |
1996-04-25 |
2023-08-12 |
human |
| A W Deckel, E Vavrousek-Jakuba, W J Shoemake. Prefrontal levels of 5-HIAA, but not dopamine, predict alcohol consumption in male Wistar rats following 6-OHDA lesions. Alcohol (Fayetteville, N.Y.). vol 12. issue 6. 1996-04-03. PMID:8590620. |
they further suggest that mpfc serotonergic systems may play an important role in the regulation of alcohol consumption, although future experimentation directly manipulating 5-ht systems in the mpfc will be required to fully assess these findings. |
1996-04-03 |
2023-08-12 |
rat |
| C S Nelson, R D Cone, L S Robbins, C N Allen, J P Adelma. Cloning and expression of a 5HT7 receptor from Xenopus laevis. Receptors & channels. vol 3. issue 1. 1996-03-25. PMID:8589994. |
a rank order of potency was obtained for serotonergic agonists of 5-hydroxytryptamine (5ht) > or = 5-methoxytryptamine (5meoxyt) > or = alpha-methyl-5-hydroxytryptamine (alpha me5ht) > 8-oh-dpat, and for serotonergic antagonists of ritanserin > nan190 > mesulergine not equal to pindolol. |
1996-03-25 |
2023-08-12 |
xenopus_laevis |
| T Urano, J Malyszko, Y Takada, A Takad. Close relationships between serotonergic and fibrinolytic systems revealed by a monoamine oxidase inhibitor treatment in rats. Haemostasis. vol 25. issue 6. 1996-03-22. PMID:8586318. |
in order to investigate a possible relationship between serotonergic and fibrinolytic systems, serotonin (5-hydroxytryptamine, 5-ht) metabolism was modified by the use of a monoamine oxidase inhibitor (tranylcypromine: 10 mg/kg body weight) and its effect on the fibrinolytic system was analyzed. |
1996-03-22 |
2023-08-12 |
rat |
| A N Singh, C Barlas, S Singh, P Franks, R K Mishr. A neurochemical basis for the antipsychotic activity of loxapine: interactions with dopamine D1, D2, D4 and serotonin 5-HT2 receptor subtypes. Journal of psychiatry & neuroscience : JPN. vol 21. issue 1. 1996-03-21. PMID:8580115. |
the findings indicate that loxapine displays an extremely strong binding affinity for dopamine d4 and serotonin 5-ht2 receptors, which suggests that both serotonergic and dopaminergic mechanisms contribute to the antipsychotic drug action and eps associated with loxapine in the treatment of schizophrenia. |
1996-03-21 |
2023-08-12 |
Not clear |
| G Leanza, S Perez, R Pellitteri, A Russo, S Stanzan. Branching serotonergic and non-serotonergic projections from caudal brainstem to the medial preoptic area and the lumbar spinal cord, in the rat. Neuroscience letters. vol 200. issue 1. 1996-03-19. PMID:8584265. |
the results suggest that (1) neurons in the caudal raphe nuclei exhibit highly collateralized axons, able to simultaneously innervate rostrally- and caudally-located targets; (2) a large proportion (40-50%) of the raphe-spinal projection does not contain serotonin, which by contrast is present in more than 70% of the neurons projecting to the medial preoptic area; (3) only a small fraction of the observed collateralized projection is serotonergic. |
1996-03-19 |
2023-08-12 |
rat |
| A Kulikov, N Castanon, P Mormède, F Chaoulof. Cerebral tryptophan hydroxylase activity, and 5-HT1A receptor, 5-HT2A receptor, and 5-HT transporter binding in grouped and isolated Roman RHA and RLA rats: relationships with behaviours in two models of anxiety. Psychopharmacology. vol 121. issue 3. 1996-03-19. PMID:8584622. |
herein, we have analysed the impact of prior isolation on male roman rats tested in the first two models of anxiety; moreover, because central serotonin (5-ht) systems in roman rats have been scarcely studied, we have also analysed several anxiety-related indices of central serotonergic activity in grouped/isolated roman rats. |
1996-03-19 |
2023-08-12 |
rat |
| b' L Hern\\xc3\\xa1di, L Erd\\xc3\\xa9lyi, A P\\xc3\\xa1rducz, H Szabadi, G Such, G Jancs\\xc3\\xb. In vitro capsaicin-induced cytological changes and alteration in calcium distribution in giant serotonergic neurons of the snail Helix pomatia: a light- and electron-microscopic study. Cell and tissue research. vol 282. issue 3. 1996-03-15. PMID:8581938.' |
capsaicin at a concentration of 10(-4)m caused characteristic structural alterations in the giant serotonergic neurons but did not significantly influence serotonin immunoreactivity in the neurons. |
1996-03-15 |
2023-08-12 |
Not clear |
| A M Evangelista de Duffard, A Brusco, R Duffard, G García, J Pecci Saavedr. Changes in serotonin-immunoreactivity in the dorsal and median raphe nuclei of rats exposed to 2,4-dichlorophenoxyacetic acid through lactation. Molecular and chemical neuropathology. vol 26. issue 2. 1996-03-14. PMID:8573243. |
we postulate that exposure to 2,4-dichlorophenoxyacetic acid on the first day of life would modify the synthesis of 5-ht or the maturation of the brain serotonergic system. |
1996-03-14 |
2023-08-12 |
rat |
| A M Zardetto-Smith, A K Johnso. Chemical topography of efferent projections from the median preoptic nucleus to pontine monoaminergic cell groups in the rat. Neuroscience letters. vol 199. issue 3. 1996-03-13. PMID:8577401. |
this study examined efferent output from the median preoptic nucleus (mnpo) to pontine noradrenergic and serotonergic cell groups using an anterograde tracing technique (phaseolus vulgaris leucoagglutinin, pha-l) combined with glucose oxidase immunocytochemistry to serotonin (5-ht) or to dopamine-beta-hydroxylase (dbh). |
1996-03-13 |
2023-08-12 |
rat |
| R I Westphalen, P R Dod. The nature of d,l-fenfluramine-induced 5-HT reuptake transporter loss in rats. Molecular neurobiology. vol 11. issue 1-3. 1996-03-07. PMID:8561960. |
alternatively, fenfluramine may destroy the serotonergic terminals on which 5-ht transporters are located. |
1996-03-07 |
2023-08-12 |
rat |
| R I Westphalen, P R Dod. The nature of d,l-fenfluramine-induced 5-HT reuptake transporter loss in rats. Molecular neurobiology. vol 11. issue 1-3. 1996-03-07. PMID:8561960. |
in model 1, serotonergic nerve terminals were destroyed (rats received 5,7-dihydroxytryptamine [5,7-dht] intracisternally); in model 2, there was a loss of 5-ht transporter per se on otherwise intact serotonergic nerve terminals. |
1996-03-07 |
2023-08-12 |
rat |
| D B Miller, J P O'Callagha. The role of temperature, stress, and other factors in the neurotoxicity of the substituted amphetamines 3,4-methylenedioxymethamphetamine and fenfluramine. Molecular neurobiology. vol 11. issue 1-3. 1996-03-07. PMID:8561961. |
amphetamines (amps) can cause long-term depletions in striatal dopamine (da) and serotonin (5-ht), and these decrements are often accepted as prima facie evidence of amp-induced damage to the dopaminergic and serotonergic projections to striatum. |
1996-03-07 |
2023-08-12 |
mouse |
| D Samoil, B P Grub. Neurally mediated syncope and serotonin reuptake inhibitors. Clinical autonomic research : official journal of the Clinical Autonomic Research Society. vol 5. issue 5. 1996-03-01. PMID:8563456. |
this brief review provides a summary of serotonergic blood pressure regulation, as well as the initial experience with the clinical effects of the serotonin reuptake inhibitors in the therapy of the aforementioned disorders. |
1996-03-01 |
2023-08-12 |
Not clear |