| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Herrsted. New perspectives in antiemetic treatment. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. vol 4. issue 6. 1997-03-06. PMID:8961471. |
a possible antiemetic effect, achieved by interference with the "serotonergic system", is not restricted to antagonism at 5-ht3 receptors, however, but also includes agonism at 5-ht1a and 5-ht2 receptors, and serotonin synthesis inhibitors. |
1997-03-06 |
2023-08-12 |
Not clear |
| P Netter, J Hennig, I S Roe. Serotonin and dopamine as mediators of sensation seeking behavior. Neuropsychobiology. vol 34. issue 3. 1997-03-04. PMID:8916073. |
in studies 1 and 2 responsivity to a serotonergic (5-ht) challenge by a 5-ht1a receptor agonist (ipsapirone) was investigated by drug-induced prolactin (prl) and cortisol responses, as well as by emotional states and behavioral measures. |
1997-03-04 |
2023-08-12 |
human |
| P Netter, J Hennig, I S Roe. Serotonin and dopamine as mediators of sensation seeking behavior. Neuropsychobiology. vol 34. issue 3. 1997-03-04. PMID:8916073. |
these findings were found compatible with the idea of a generally low responsivity of the serotonergic system in high es as well as in high dis types of sensation seekers of 5-ht1a subsensitivity in high dis and subsensitivity of other postsynaptic 5-ht receptors in high es. |
1997-03-04 |
2023-08-12 |
human |
| D Koszycki, R M Zacharko, J M Le Melledo, S N Young, J Bradwej. Effect of acute tryptophan depletion on behavioral, cardiovascular, and hormonal sensitivity to cholecystokinin-tetrapeptide challenge in healthy volunteers. Biological psychiatry. vol 40. issue 7. 1997-02-21. PMID:8886299. |
recent data suggest that serotonergic (5-ht) mechanisms may mediate the anxiogenic effects of cholecystokinin (cck)-related peptides. |
1997-02-21 |
2023-08-12 |
human |
| b' V S Kosti\\xc4\\x87, D Leci\\xc4\\x87, M Doder, J Marinkovi\\xc4\\x87, S Filipovi\\xc4\\x8. Prolactin and cortisol responses to fenfluramine in Parkinson\'s disease. Biological psychiatry. vol 40. issue 8. 1997-02-21. PMID:8894070.' |
to evaluate central serotonergic function in parkinson's disease in relation to depression, we examined prolactin and cortisol responses to a single-dose challenge with fenfluramine (60 mg orally), a serotonin releasing/uptake-inhibiting agent, in the course of 5 hours in 11 patients with parkinson's disease associated with major depression (sads-rdc), 22 nondepressed parkinsonians, and 20 age- and gender-matched healthy controls. |
1997-02-21 |
2023-08-12 |
Not clear |
| H Stark, H Scheic. Dopaminergic and serotonergic neurotransmission systems are differentially involved in auditory cortex learning: a long-term microdialysis study of metabolites. Journal of neurochemistry. vol 68. issue 2. 1997-02-21. PMID:9003057. |
because of detection limits of dopamine and serotonin in auditory cortex, the response profiles of extracellular homovanillic acid as the metabolite of the dopaminergic system and of 5-hydroxyindoleacetic acid as the metabolite of the serotonergic system were determined from consecutive dialysis samples each day. |
1997-02-21 |
2023-08-12 |
Not clear |
| D Mück-Seler, M Diksi. DL-fenfluramine increases the 5-HT synthesis rate in the terminals while decreasing it in the cell bodies of the rat brain. Brain research. vol 737. issue 1-2. 1997-02-20. PMID:8930348. |
), given 20 min before tracer injection, decreased the rate of 5-ht synthesis in the serotonergic cell bodies (-32% in dorsal and -23% in median raphe nuclei) but increased the rate in almost all the terminal areas investigated when compared to the rate in the control (saline treated) rats. |
1997-02-20 |
2023-08-12 |
rat |
| N T Mathew, G E Tietjen, C Lucke. Serotonin syndrome complicating migraine pharmacotherapy. Cephalalgia : an international journal of headache. vol 16. issue 5. 1997-02-19. PMID:8869767. |
serotonin syndrome, a condition with numerous clinical neurological manifestations, is the result of central serotonergic hyperstimulation. |
1997-02-19 |
2023-08-12 |
Not clear |
| J Andrzejewska-Buczko, W Buczk. [Serotonin--its significance in physiology and pathology of the eye]. Klinika oczna. vol 98. issue 2. 1997-02-19. PMID:9026576. |
the authors have underlined the significance of serotonin in the physiology and pathology of the eye with special regards to the effectiveness of serotonergic system affecting drugs in the disturbances of vision process. |
1997-02-19 |
2023-08-12 |
Not clear |
| L Lima, M Urbina, P Matus, Y Druja. Synthesis of serotonin from 5-hydroxytryptophan in the post-crush retina: inhibition of in vitro outgrowth by the intraocular administration of the precursor. Neurochemical research. vol 21. issue 8. 1997-02-18. PMID:8895848. |
this observation, together with the fact that serotonin concentration in postcrush retina cultured in the absence of 5-hydroxytryptophan and exposed to the precursor for 60 min increased less than in the control, indicates a saturation of the serotonergic system produced by the lesion. |
1997-02-18 |
2023-08-12 |
Not clear |
| L Lima, M Urbina, P Matus, Y Druja. Synthesis of serotonin from 5-hydroxytryptophan in the post-crush retina: inhibition of in vitro outgrowth by the intraocular administration of the precursor. Neurochemical research. vol 21. issue 8. 1997-02-18. PMID:8895848. |
thus, there is a reciprocal interaction, since serotonin influences outgrowth in the postcrush retina and the serotonergic system is modulated by the crush, indicating a mechanism of feed-back regulation. |
1997-02-18 |
2023-08-12 |
Not clear |
| S B Kasture, S N Mandhane, C T Chopd. Baclofen-induced catatonia: modification by serotonergic agents. Neuropharmacology. vol 35. issue 5. 1997-02-13. PMID:8887967. |
all serotonergic drugs were injected intraperitoneally 30 min prior to baclofen, except the 5-ht synthesis inhibitor p-chlorophenylalanine (pcpa), which was injected 72 and 48 hr prior to baclofen. |
1997-02-13 |
2023-08-12 |
rat |
| A Chattopadhyay, R Rukmini, S Mukherje. Photophysics of a neurotransmitter: ionization and spectroscopic properties of serotonin. Biophysical journal. vol 71. issue 4. 1997-02-11. PMID:8889169. |
in view of the multiple roles played by the serotonergic systems in the central and peripheral nervous systems, these results are relevant to future studies of serotonin and its binding to its receptors. |
1997-02-11 |
2023-08-12 |
Not clear |
| N J Peningto. Actions of methoxylated amphetamine hallucinogens on serotonergic neurons of the brain. Progress in neuro-psychopharmacology & biological psychiatry. vol 20. issue 6. 1997-02-07. PMID:8888103. |
previous studies of phenethylamine hallucinogenic drugs have reported that intravenous injection of doi or similar compounds produce an inhibition of the firing rate of serotonergic dorsal raphe neurons of the rat; potentially lowering levels of 5-ht throughout the brain. |
1997-02-07 |
2023-08-12 |
human |
| B Rörig, B Suto. Serotonin regulates gap junction coupling in the developing rat somatosensory cortex. The European journal of neuroscience. vol 8. issue 8. 1997-02-06. PMID:8921259. |
the 1,4,5-inositol triphosphate (ip3) receptor antagonist heparin as well as the protein kinase c inhibitor npc 15437 suppressed the uncoupling action of 5-ht, suggesting that the serotonergic effect involved ip3 receptor-mediated release of calcium ions from intracellular stores. |
1997-02-06 |
2023-08-12 |
rat |
| M T Martin-Iverson, C A Alta. Spontaneous behaviours of rats are differentially affected by substantia nigra infusions of brain-derived neurotrophic factor and neurotrophin-3. The European journal of neuroscience. vol 8. issue 8. 1997-02-06. PMID:8921260. |
most of the behavioural effects of the neurotrophins are consistent with the view that bdnf increases activity of both dopaminergic and serotonergic systems within the nigrostriatal system, and that nt-3 increases serotonin activity. |
1997-02-06 |
2023-08-12 |
rat |
| G E Pickard, E T Weber, P A Scott, A F Riberdy, M A Re. 5HT1B receptor agonists inhibit light-induced phase shifts of behavioral circadian rhythms and expression of the immediate-early gene c-fos in the suprachiasmatic nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 24. 1997-02-06. PMID:8987845. |
retinal afferents mediate photic entrainment of the scn, whereas the serotonergic afferents originating from the midbrain modulate photic responses in the scn; however, the serotonin (5ht) receptor subtypes in the scn responsible for these modulatory effects are not well characterized. |
1997-02-06 |
2023-08-12 |
Not clear |
| S A Chon. Schizophrenia and kleptomania: a case report--a biological link? Annals of the Academy of Medicine, Singapore. vol 24. issue 6. 1997-02-04. PMID:8838996. |
the role of serotonin in schizophrenia is also briefly reviewed and an abnormality in serotonergic neurotransmission is proposed to be a possible link between these two conditions. |
1997-02-04 |
2023-08-12 |
Not clear |
| O Naesh, I Hindberg, C Christianse. Subarachnoid bupivacaine increases human cerebrospinal fluid concentration of serotonin. Regional anesthesia. vol 21. issue 5. 1997-01-31. PMID:8896006. |
activation of descending serotonergic neurons or topically applied 5-ht at the spinal cord inhibits rostral spread of sensory information. |
1997-01-31 |
2023-08-12 |
human |
| F König, M Löble, M Wolfersdor. [Depressive stupor--malignant neuroleptic syndrome--serotonin syndrome. A case contribution to a difficult differential diagnosis]. Der Nervenarzt. vol 67. issue 5. 1997-01-29. PMID:9005353. |
the serotonin syndrome, however, a potentially life-threatening side effect of treatment with serotonergic substances, has been included in the clinical differential diagnosis increasingly often in the last few years. |
1997-01-29 |
2023-08-12 |
Not clear |