| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V Ljubić-Thibal, M Diksic, E Hamel, S Raison, J F Pujol, D Weissman. Ipsilateral alterations in tryptophan hydroxylase activity in rat brain after hypothalamic 5,7-di-hydroxytryptamine lesion. Brain research. vol 724. issue 2. 1996-12-26. PMID:8828572. |
five days after the lesion, the relationships between tph and its synthetic product 5-ht were evaluated on adjacent brain sections in serotonergic cells bodies of the dorsal raphe nucleus (drn) and nerve fibres of the medial forebrain bundle (mfb). |
1996-12-26 |
2023-08-12 |
rat |
| V Ljubić-Thibal, M Diksic, E Hamel, S Raison, J F Pujol, D Weissman. Ipsilateral alterations in tryptophan hydroxylase activity in rat brain after hypothalamic 5,7-di-hydroxytryptamine lesion. Brain research. vol 724. issue 2. 1996-12-26. PMID:8828572. |
moreover, the data show that a local disruption of serotonergic terminals in the dorsolateral hypothalamus does not affect 5-ht synthesis in the overall ipsilateral drn neurons but results in local activation of tph within the serotonergic projection neurons and the ipsilateral mfb, as evidenced by active de novo synthesis of 5-ht. |
1996-12-26 |
2023-08-12 |
rat |
| V Ljubić-Thibal, M Diksic, E Hamel, S Raison, J F Pujol, D Weissman. Ipsilateral alterations in tryptophan hydroxylase activity in rat brain after hypothalamic 5,7-di-hydroxytryptamine lesion. Brain research. vol 724. issue 2. 1996-12-26. PMID:8828572. |
altogether the results point to circumscribed activation of compensatory mechanisms in 5-ht synthesis after selective destruction of serotonergic terminals. |
1996-12-26 |
2023-08-12 |
rat |
| C A Stockmeier, L A Shapiro, J W Haycock, P A Thompson, M T Low. Quantitative subregional distribution of serotonin1A receptors and serotonin transporters in the human dorsal raphe. Brain research. vol 727. issue 1-2. 1996-12-23. PMID:8842377. |
these data in the human dr indicate that serotonin1a receptors are differentially distributed among the subnuclei and along the rostro-caudal axis of the midbrain raphe, and serotonin transporters appear to be relatively evenly distributed throughout the dr. subregional analyses of such serotonergic markers may prove useful in evaluating the role that serotonin may play in depression, schizophrenia, and suicide. |
1996-12-23 |
2023-08-12 |
human |
| K R Powell, L A Dykstr. The role of serotonergic receptors in the effects of mu opioids in squirrel monkeys responding under a titration procedure. Psychopharmacology. vol 126. issue 1. 1996-12-23. PMID:8853215. |
this experiment was conducted to determine whether drugs acting on brain serotonin modulate the effects of the mu opioid, morphine, as measured by the squirrel monkey shock titration procedure and, if so, whether serotonergic modulation is mediated via specific 5ht receptor subtypes. |
1996-12-23 |
2023-08-12 |
monkey |
| D Mück-Seler, A Jevric-Causevic, M Diksi. Influence of fluoxetine on regional serotonin synthesis in the rat brain. Journal of neurochemistry. vol 67. issue 6. 1996-12-23. PMID:8931476. |
the results suggest that extracellular 5-ht has a delayed influence on the brain 5-ht synthesis rate in structures with serotonergic terminals. |
1996-12-23 |
2023-08-12 |
rat |
| D Mück-Seler, A Jevric-Causevic, M Diksi. Influence of fluoxetine on regional serotonin synthesis in the rat brain. Journal of neurochemistry. vol 67. issue 6. 1996-12-23. PMID:8931476. |
in addition, the findings, from the chronic treatment study might give us a better understanding of how the brain serotonergic system adapts during a prolonged exposure to extracellular 5-ht. |
1996-12-23 |
2023-08-12 |
rat |
| J F Neumaier, P Szot, E R Peskind, D M Dorsa, M W Hambli. Serotonergic lesioning differentially affects presynaptic and postsynaptic 5-HT1B receptor mRNA levels in rat brain. Brain research. vol 722. issue 1-2. 1996-12-18. PMID:8813349. |
furthermore, although both 5-ht1b receptor and serotonin transporters are found in serotonergic terminals, their levels may be regulated differentially during the period of regrowth that follows chemical axotomy. |
1996-12-18 |
2023-08-12 |
rat |
| H Tamir, S C Hsiung, K P Liu, R D Blakely, A F Russo, M S Clark, E A Nunez, M D Gersho. Expression and development of a functional plasmalemmal 5-hydroxytryptamine transporter by thyroid follicular cells. Endocrinology. vol 137. issue 10. 1996-12-18. PMID:8828510. |
a 5-ht transporter (sert) in the plasma membrane of serotonergic neurons inactivates neuronal 5-ht. |
1996-12-18 |
2023-08-12 |
mouse |
| D Pawlak, J Malyszko, J S Malyszko, K Pawlak, W Buczko, M Mysliwie. Peripheral serotonergic system in uremia. Thrombosis research. vol 83. issue 2. 1996-12-18. PMID:8837318. |
thus, we focused on peripheral serotonergic mechanisms including 5-ht uptake and release and kinetics of its uptake in uremic patients. |
1996-12-18 |
2023-08-12 |
Not clear |
| T Oyama, M Ueda, Y Kuraishi, A Akaike, M Sato. Dual effect of serotonin on formalin-induced nociception in the rat spinal cord. Neuroscience research. vol 25. issue 2. 1996-12-13. PMID:8829149. |
to examine the role of the descending serotonergic system in the regulation of spinal nociceptive processing, the effects of serotonin (5-ht) and selective ligands for 5-ht receptor subtypes on persistent nociception were investigated. |
1996-12-13 |
2023-08-12 |
rat |
| K J Bobrzynska, M H Godfrey, N Mrosovsk. Serotonergic stimulation and nonphotic phase-shifting in hamsters. Physiology & behavior. vol 59. issue 2. 1996-12-05. PMID:8838598. |
the serotonergic (5-ht) projection from the raphe to the suprachiasmatic nucleus (scn) is a possible route by which nonphotic information could reach the pacemaker. |
1996-12-05 |
2023-08-12 |
rat |
| M A Geye. Serotonergic functions in arousal and motor activity. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788473. |
the fact that the predominant effect of serotonin releasers is locomotor activation, apparently mediated via post-synaptic 5-ht1b receptors, suggests that some endogenous serotonergic systems may normally activate rather than suppress motor output. |
1996-12-04 |
2023-08-12 |
rat |
| K J Simansk. Serotonergic control of the organization of feeding and satiety. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788474. |
studies in which serotonergic drugs were administered either systemically or directly into central sites have implicated 5-ht in the inhibitory control of feeding in mammals. |
1996-12-04 |
2023-08-12 |
rat |
| K J Simansk. Serotonergic control of the organization of feeding and satiety. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788474. |
in animal models and in humans, 5-ht agonists such as fenfluramine, fluoxetine and sertraline reduced the rate of eating and the size of meals in a manner suggesting that increasing serotonergic neurotransmission specifically enhanced satiation. |
1996-12-04 |
2023-08-12 |
rat |
| D L Murphy, C Aulakh, P Mazzola-Pomietto, N C Brigg. Neuroendocrine responses to serotonergic agonists as indices of the functional status of central serotonin neurotransmission in humans: a preliminary comparative analysis of neuroendocrine endpoints versus other endpoint measures. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788504. |
neuroendocrine responses to serotonergic agonists as indices of the functional status of central serotonin neurotransmission in humans: a preliminary comparative analysis of neuroendocrine endpoints versus other endpoint measures. |
1996-12-04 |
2023-08-12 |
human |
| D L Murphy, C Aulakh, P Mazzola-Pomietto, N C Brigg. Neuroendocrine responses to serotonergic agonists as indices of the functional status of central serotonin neurotransmission in humans: a preliminary comparative analysis of neuroendocrine endpoints versus other endpoint measures. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788504. |
the status of central serotonergic neurotransmission and of specific serotonin (5-ht) receptor subtype sensitivity has been inferred from neuroendocrine and other endpoint responses to serotonergic agents given to humans. |
1996-12-04 |
2023-08-12 |
human |
| G Fillion, J C Rousselle, O Massot, E Zifa, M P Fillion, N Prudhomm. A new peptide, 5-HT-moduline, isolated and purified from mammalian brain specifically interacts with 5-HT1B/1D receptors. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788526. |
the observed interaction may lead to functional alterations of 5-ht1b/1d receptors known to play an important role in regulating the release of 5-ht from serotonergic nerve terminals (autoreceptors) as well as the release of other neurotransmitters (heteroreceptors). |
1996-12-04 |
2023-08-12 |
rat |
| T D Patel, E C Azmitia, F C Zho. Increased 5-HT1A receptor immunoreactivity in the rat hippocampus following 5,7-dihydroxytryptamine lesions in the cingulum bundle and fimbria-fornix. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788527. |
microinjection of the serotonergic neurotoxin 5,7-dihydroxytryptamine (5,7-dht) into the cb and ff produces a significant decrease in the density of 5-ht immunoreactive fibers in the hippocampus as early as 3 days postlesion (zhou, f.c. |
1996-12-04 |
2023-08-12 |
rat |
| L Sundi. Serotonergic vasomotor control in fish gills. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 28. issue 11-12. 1996-12-03. PMID:8728850. |
serotonin (5-hydroxytryptamine,5-ht)-containing neuroepithelial cells (necs) have been discovered in the gills of fish belonging to different phylogenetic groups, and an additional serotonergic innervation of the gill filaments is present in teleosts. |
1996-12-03 |
2023-08-12 |
Not clear |