| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Schmitz, R M Empson, T Gloveli, U Heineman. Serotonin blocks different patterns of low Mg2+-induced epileptiform activity in rat entorhinal cortex, but not hippocampus. Neuroscience. vol 76. issue 2. 1997-04-29. PMID:9015329. |
given the strong serotonergic inputs to both the hippocampus and entorhinal cortex, the differential sensitivity of the two regions to serotonin suggests functional differences. |
1997-04-29 |
2023-08-12 |
rat |
| R P Vertes, A M Cran. Distribution, quantification, and morphological characteristics of serotonin-immunoreactive cells of the supralemniscal nucleus (B9) and pontomesencephalic reticular formation in the rat. The Journal of comparative neurology. vol 378. issue 3. 1997-04-29. PMID:9034900. |
the sln (b9) contains more 5-ht neurons than any serotonergic group other than the dorsal raphe nucleus. |
1997-04-29 |
2023-08-12 |
rat |
| A Panconesi, R Sicuter. Headache induced by serotonergic agonists--a key to the interpretation of migraine pathogenesis? Cephalalgia : an international journal of headache. vol 17. issue 1. 1997-04-29. PMID:9051329. |
this has led to opposing theories concerning the role of 5-hydroxytryptamine (5ht) in triggering migraine attacks; is there hyperfunction or hypofunction of the central serotonergic system. |
1997-04-29 |
2023-08-12 |
Not clear |
| H J Möller, H P Vol. Drug treatment of depression in the 1990s. An overview of achievements and future possibilities. Drugs. vol 52. issue 5. 1997-04-22. PMID:9118813. |
the major properties of selective serotonin reuptake inhibitors, reversible and selective inhibitors of monoamine oxidase type a, selective serotonin and noradrenaline reuptake inhibitors, and noradrenergic and specific serotonergic antidepressants are discussed. |
1997-04-22 |
2023-08-12 |
Not clear |
| R Davis, D Fauld. Dexfenfluramine. An updated review of its therapeutic use in the management of obesity. Drugs. vol 52. issue 5. 1997-04-22. PMID:9118819. |
dexfenfluramine increases serotonergic activity by stimulating serotonin (5-hydroxytryptamine; 5-ht) release into brain synapses, inhibiting its reuptake into presynaptic neurons and by directly stimulating postsynaptic serotonin receptors. |
1997-04-22 |
2023-08-12 |
Not clear |
| S A Barman, J R Pauly, C M Isale. Canine pulmonary vasoreactivity to serotonin: role of protein kinase C and tyrosine kinase. The American journal of physiology. vol 272. issue 2 Pt 2. 1997-04-22. PMID:9124433. |
the 5-ht2-receptor blocker ketanserin (10(-7) m), the protein kinase c inhibitor staurosporine (10(-7) m), the voltage-dependent ca2+-channel blocker verapamil (10(-5) m), and the specific protein tyrosine kinase inhibitors genistein (5 x 10(-4) m) and tyrphostin 25 (5 x 10(-4) m) completely inhibited the pressor response to 5-ht, whereas the 5-ht1-receptor antagonist (-)pindolol (10(-7) m) had no significant effect on the serotonergic response. |
1997-04-22 |
2023-08-12 |
dog |
| D Mück-Seler, M Diksi. Serotonin synthesis increased in terminals four days after reserpine treatment: an autoradiographic study in rat brain. Neurochemical research. vol 22. issue 1. 1997-04-16. PMID:9021755. |
the results show that the rate of 5-ht synthesis was unchanged in the dorsal and median raphe, significantly decreased in the raphe magnus, and significantly increased in areas rich in serotonergic nerve terminals (i.e., hypothalamus, hippocampus, median geniculate body, parietal and visual cortices). |
1997-04-16 |
2023-08-12 |
rat |
| Y Liu, C J Tseng, N G Huang, T H Yin, C S Tun. Serotonergic serotonin 2 receptor modulation on DOPAC and 5-HIAA levels in rat striatum and nucleus accumbens: microdialysis studies of freely moving rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 20. issue 2. 1997-04-11. PMID:8861195. |
serotonergic serotonin 2 receptor modulation on dopac and 5-hiaa levels in rat striatum and nucleus accumbens: microdialysis studies of freely moving rats. |
1997-04-11 |
2023-08-12 |
rat |
| D H Overstreet, A H Rezvani, O Pucilowski, D S Janowsk. 5-HT receptors: implications for the neuropharmacology of alcohol and alcoholism. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. vol 2. 1997-04-07. PMID:8974337. |
the involvement of serotonergic mechanisms in the neuropharmacology of alcohol was appreciated before it was recognized that there were multiple subtypes of serotonin (5-hydroxytryptamine; 5-ht) receptors. |
1997-04-07 |
2023-08-12 |
rat |
| D H Overstreet, A H Rezvani, O Pucilowski, D S Janowsk. 5-HT receptors: implications for the neuropharmacology of alcohol and alcoholism. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. vol 2. 1997-04-07. PMID:8974337. |
thus, it was known that manipulations of the central serotonergic system could lead to a modification of the rate of tolerance development to alcohol (frankel et al., 1975) or to a modulation of alcohol intake (myers and martin, 1973; myers and melchior, 1975) before peroutka and snyder (1979) first suggested that there were at least two subtypes of 5-ht receptors. |
1997-04-07 |
2023-08-12 |
rat |
| E M Seller. Biobehavioural basis of pharmacologic treatment of alcohol dependence. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. vol 2. 1997-04-07. PMID:8974377. |
this paper will review four main issues; the meaning of "craving", the role of serotonin in the neuroregulation of ethanol consumption and the effect of serotonergic drugs on ethanol intake, the role of other neurotransmitter systems, and how pharmacological treatments can be combined with psychosocial approaches. |
1997-04-07 |
2023-08-12 |
Not clear |
| L Buydens-Branchey, M Branchey, P Fergeson, J Hudson, C McKerni. Craving for cocaine in addicted users. Role of serotonergic mechanisms. The American journal on addictions. vol 6. issue 1. 1997-04-04. PMID:9097873. |
the authors evaluated whether the acute increase in serotonergic neurotransmission after the administration of a challenging dose of the 5-ht partial agonist meta-chlorophenylpiperazine (m-cpp) had an effect on spontaneous cocaine craving. |
1997-04-04 |
2023-08-12 |
Not clear |
| A F Russo, M S Clark, P L Durha. Thyroid parafollicular cells. An accessible model for the study of serotonergic neurons. Molecular neurobiology. vol 13. issue 3. 1997-04-02. PMID:8989773. |
furthermore, pf cells and pf cell lines are capable of expressing the fundamental properties of serotonergic neurons, including: (1) serotonin (5-ht) biosynthesis by tryptophan hydroxylase (tph), (2) vesicular 5-ht storage and regulated release, (3) expression of a 5-ht autoreceptor, and (4) expression of the 5-ht transporter. |
1997-04-02 |
2023-08-12 |
rat |
| K J Bobrzynska, N Vrang, N Mrosovsk. Persistence of nonphotic phase shifts in hamsters after serotonin depletion in the suprachiasmatic nucleus. Brain research. vol 741. issue 1-2. 1997-04-02. PMID:9001724. |
therefore we studied the role of the serotonergic projection to the scn in nonphotic phase shifts by bilateral injection of the selective 5-ht neurotoxin, 5,7-dihydroxytryptamine (5,7-dht) onto the scn of hamsters. |
1997-04-02 |
2023-08-12 |
Not clear |
| A Dugar, J M Lakosk. Serotonergic function of aging hippocampal CA3 pyramidal neurons: electrophysiological assessment following administration of 5,7-dihydroxytryptamine in the fimbria-fornix and cingulum bundle. Journal of neuroscience research. vol 47. issue 1. 1997-03-26. PMID:8981238. |
serotonergic (5-hydroxytryptamine; 5-ht) neurotransmission has been implicated in the regulation of cognitive function and this neurotransmitter system may underlie selective neuronal degeneration found in the aging hippocampus. |
1997-03-26 |
2023-08-12 |
rat |
| A Dugar, J M Lakosk. Serotonergic function of aging hippocampal CA3 pyramidal neurons: electrophysiological assessment following administration of 5,7-dihydroxytryptamine in the fimbria-fornix and cingulum bundle. Journal of neuroscience research. vol 47. issue 1. 1997-03-26. PMID:8981238. |
age-dependent changes in 5-ht function of hippocampal ca3 subfield pyramidal neurons were evaluated in female fischer 344 rats (2 and 17 months) following denervation of the serotonergic afferents to the dorsal hippocampus using the neurotoxin 5,7-dihydroxytryptamine (5,7-dht). |
1997-03-26 |
2023-08-12 |
rat |
| R N Clark, C R Ashby, S L Dewey, P V Ramachandran, R E Strecke. Effect of acute and chronic fluoxetine on extracellular dopamine levels in the caudate-putamen and nucleus accumbens of rat. Synapse (New York, N.Y.). vol 23. issue 3. 1997-03-24. PMID:8807740. |
recent studies indicate that an increase in serotonergic (5-ht) activity in the nucleus accumbens (nac) produces an increase in dopamine (da) release, providing a possible mechanism for the involvement of da in the therapeutic action of selective serotonin reuptake inhibitor (ssri) antidepressants. |
1997-03-24 |
2023-08-12 |
rat |
| D H Overstreet, A H Rezvan. Behavioral differences between two inbred strains of Fawn-Hooded rat: a model of serotonin dysfunction. Psychopharmacology. vol 128. issue 3. 1997-03-24. PMID:8972553. |
the fawn-hooded rat (fh) strain has attracted the attention of some psychopharmacologists because of reports of its exaggerated immobility in the swim test, hypercortisolemia, excessive voluntary intake of alcohol, platelet and central serotonin abnormalities and subsensitivity to serotonergic agonists. |
1997-03-24 |
2023-08-12 |
rat |
| C Scavini, A Rozza, E Lanza, L Favalli, G Racagni, N Brunell. Effect of idebenone on in vivo serotonin release and serotonergic receptors in young and aged rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 6. issue 2. 1997-03-21. PMID:8791034. |
effect of idebenone on in vivo serotonin release and serotonergic receptors in young and aged rats. |
1997-03-21 |
2023-08-12 |
rat |
| J D Silva, M T Nune. Facilitatory role of serotonin (5-HT) in the control of thyrotropin releasing hormone/thyrotropin (TRH/TSH) secretion in rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 29. issue 5. 1997-03-20. PMID:9033822. |
in order to investigate the role of serotonin in the regulation of thyrotropin (tsh) secretion, control and propylthiouracil (ptu)-treated male wistar rats weighing approximately 250 g were subjected to ip injections of methysergide (met, 10 micrograms/100 g body weight), a serotonergic receptor blocker, and killed 60 min later by decapitation. |
1997-03-20 |
2023-08-12 |
rat |