| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jun Yin, Ross H Albert, Anna P Tretiakova, Bradford A Jameso. 5-HT(1B) receptors play a prominent role in the proliferation of T-lymphocytes. Journal of neuroimmunology. vol 181. issue 1-2. 2007-02-06. PMID:17011639. |
serotonin plays a role in t cell activation, but there is no clear consensus of which of the 14 serotonergic receptors control this activations pathway. |
2007-02-06 |
2023-08-12 |
human |
| Jun Yin, Ross H Albert, Anna P Tretiakova, Bradford A Jameso. 5-HT(1B) receptors play a prominent role in the proliferation of T-lymphocytes. Journal of neuroimmunology. vol 181. issue 1-2. 2007-02-06. PMID:17011639. |
as a whole, our data suggest that other serotonergic receptors may contribute to the proliferative signals, but the 5-ht(1b) receptor plays the most dominant role. |
2007-02-06 |
2023-08-12 |
human |
| Paul J Fletcher, Judy Sinyard, Guy A Higgin. The effects of the 5-HT(2C) receptor antagonist SB242084 on locomotor activity induced by selective, or mixed, indirect serotonergic and dopaminergic agonists. Psychopharmacology. vol 187. issue 4. 2007-02-02. PMID:16832658. |
the effects of the 5-ht(2c) receptor antagonist sb242084 on locomotor activity induced by selective, or mixed, indirect serotonergic and dopaminergic agonists. |
2007-02-02 |
2023-08-12 |
Not clear |
| Bin Liang, Mustapha Moussaif, Chih-Jen Kuan, J Jay Gargus, Ji Ying Sz. Serotonin targets the DAF-16/FOXO signaling pathway to modulate stress responses. Cell metabolism. vol 4. issue 6. 2007-02-02. PMID:17141627. |
genetic analyses imply that daf-2 is a downstream target of 5ht signaling and that distinct serotonergic neurons act through distinct 5ht receptors to influence distinct daf-16-mediated stress responses. |
2007-02-02 |
2023-08-12 |
caenorhabditis_elegans |
| Kishore M Gadde, Harry Ryan Wagner, Kathryn M Connor, Mariko S Fous. Escitalopram treatment of trichotillomania. International clinical psychopharmacology. vol 22. issue 1. 2007-02-02. PMID:17159458. |
with the understanding that serotonergic drugs might curb compulsive hair pulling, we conducted a preliminary investigation examining the effectiveness of escitalopram, a potent and selective serotonin uptake inhibitor, in the treatment of trichotillomania. |
2007-02-02 |
2023-08-12 |
Not clear |
| Shih-Jen Tsa. The P11, tPA/plasminogen system and brain-derived neurotrophic factor: Implications for the pathogenesis of major depression and the therapeutic mechanism of antidepressants. Medical hypotheses. vol 68. issue 1. 2007-01-30. PMID:16890384. |
evidence from animal and human studies suggests that a disturbance in serotonergic (5-ht) activity and/or brain-derived neurotrophic factor (bdnf) signaling may be implicated in the pathogenesis of mdd. |
2007-01-30 |
2023-08-12 |
mouse |
| Ann M Thompso. "Non-serotonergic" lateral superior olivary neurons of the neonatal mouse contain serotonin. Brain research. vol 1122. issue 1. 2007-01-30. PMID:17034765. |
in mutant mice which have high serotonin (5-ht) levels perinatally, neurons in the lateral superior olive (lso, which are not serotonergic), contain 5-ht transiently in the neonatal period of development. |
2007-01-30 |
2023-08-12 |
mouse |
| Laura Gray, Elizabeth Scarr, Brian Dea. Serotonin 1a receptor and associated G-protein activation in schizophrenia and bipolar disorder. Psychiatry research. vol 143. issue 2-3. 2007-01-29. PMID:16831468. |
abnormalities in the serotonergic signalling system, including the serotonin 1a receptor, have been implicated in the pathogenesis of schizophrenia and bipolar 1 disorder. |
2007-01-29 |
2023-08-12 |
human |
| Roland W Freudenmann, Carlos Schönfeldt-Lecuona, Manfred Spitzer, Leopold Hermle, Georg Grö. Electroconvulsive therapy in the treatment of depression in a former ecstasy user. Journal of psychopharmacology (Oxford, England). vol 20. issue 6. 2007-01-26. PMID:16891342. |
depression in former ecstasy users may not respond to selective serotonin reuptake inhibitors (ssris) possibly due to damaged serotonergic synapses following long-term heavy ecstasy use. |
2007-01-26 |
2023-08-12 |
Not clear |
| Romain Meeusen, Philip Watson, Hiroshi Hasegawa, Bart Roelands, Maria F Piacentin. Central fatigue: the serotonin hypothesis and beyond. Sports medicine (Auckland, N.Z.). vol 36. issue 10. 2007-01-25. PMID:17004850. |
several nutritional and pharmacological studies have attempted to manipulate central serotonergic activity during exercise, but this work has yet to provide robust evidence for a significant role of serotonin in the fatigue process. |
2007-01-25 |
2023-08-12 |
Not clear |
| Vanthida Huang, Justine S Gortne. Risk of serotonin syndrome with concomitant administration of linezolid and serotonin agonists. Pharmacotherapy. vol 26. issue 12. 2007-01-25. PMID:17125439. |
a literature search revealed 13 cases of serotonin syndrome occurring with the concomitant use of linezolid and drugs possessing serotonergic properties. |
2007-01-25 |
2023-08-12 |
Not clear |
| Vanthida Huang, Justine S Gortne. Risk of serotonin syndrome with concomitant administration of linezolid and serotonin agonists. Pharmacotherapy. vol 26. issue 12. 2007-01-25. PMID:17125439. |
to direct clinical management of this potential drug interaction, we reviewed reports of serotonin syndrome to determine relevant drug interactions with linezolid and serotonergic drugs and to characterize similarities and differences in the reported cases. |
2007-01-25 |
2023-08-12 |
Not clear |
| Aihua Li, Shawn Zhou, Eugene Natti. Simultaneous inhibition of caudal medullary raphe and retrotrapezoid nucleus decreases breathing and the CO2 response in conscious rats. The Journal of physiology. vol 577. issue Pt 1. 2007-01-23. PMID:16825298. |
inhibition of caudal mr serotonergic neurons with the 5-ht(1a) receptor agonist (r)-(+)-8-hydroxy-2(di-n-propylamino)tetralin (8-oh-dpat), with simultaneous dialysis of acsf in or near to the rtn, causes hypoventilation but has no significant effect on the co(2) response. |
2007-01-23 |
2023-08-12 |
rat |
| R A Prosser, H-M Lee, A Wehne. Serotonergic pre-treatments block in vitro serotonergic phase shifts of the mouse suprachiasmatic nucleus circadian clock. Neuroscience. vol 142. issue 2. 2007-01-23. PMID:16876330. |
previous studies report clear differences in the ability of serotonergic stimuli to phase-shift the scn clock when applied directly to the scn either in vivo or in vitro: while mice and rat circadian clocks are readily phase-shifted by serotonin (5-ht) or 5-ht agonists applied in vitro, hamster and mice circadian clocks respond inconsistently to 5-ht agonists injected directly into the scn in vivo. |
2007-01-23 |
2023-08-12 |
mouse |
| R A Prosser, H-M Lee, A Wehne. Serotonergic pre-treatments block in vitro serotonergic phase shifts of the mouse suprachiasmatic nucleus circadian clock. Neuroscience. vol 142. issue 2. 2007-01-23. PMID:16876330. |
together these data support the hypothesis that scn clock sensitivity to serotonergic phase modulation is affected by the amount of prior serotonin signaling present in the scn, and that this signaling alters the density of surface 5-ht receptors on scn clock neurons. |
2007-01-23 |
2023-08-12 |
mouse |
| Patricia Campos-Bedolla, Mario H Vargas, Eduardo Calixto, Patricia Segura, Nicandro Mendoza-Patiño, Alejandra Figueroa, Edgar Flores-Soto, Carlos Barajas-López, Luis M Montañ. Alpha-methyl-5-HT, a 5-HT2 receptor agonist, stimulates beta2-adrenoceptors in guinea pig airway smooth muscle. Pharmacological research. vol 54. issue 6. 2007-01-23. PMID:17079161. |
alpha-methyl-5-ht is widely used as a high-affinity 5-ht(2) receptors agonist, though some studies have postulated that this drug also activates other serotonergic receptors. |
2007-01-23 |
2023-08-12 |
Not clear |
| Biao Wang, Farid F Cheha. Deletion of the serotonin 2c receptor from transgenic mice overexpressing leptin does not affect their lipodystrophy but exacerbates their diet-induced obesity. Biochemical and biophysical research communications. vol 351. issue 2. 2007-01-19. PMID:17064660. |
projections of serotonergic neurons onto pomc neurons suggest that leptin and serotonin converge onto pomc neurons to regulate body weight. |
2007-01-19 |
2023-08-12 |
mouse |
| Camilla I Svensson, Thao K Tran, Bethany Fitzsimmons, Tony L Yaksh, Xiao-Ying Hu. Descending serotonergic facilitation of spinal ERK activation and pain behavior. FEBS letters. vol 580. issue 28-29. 2007-01-19. PMID:17113581. |
depletion of spinal 5-ht by intrathecal (it) 5,7-dht, a serotonergic neurotoxin, profoundly reduced formalin evoked flinching and the increase in p-erk1/2. |
2007-01-19 |
2023-08-12 |
rat |
| O Trummer, H Köppel, T C Wascher, G Grünbacher, M Gutjahr, O Stanger, S Ramschak-Schwarzer, B O Boehm, B R Winkelmann, W März, W Renne. The serotonin transporter gene polymorphism is not associated with smoking behavior. The pharmacogenomics journal. vol 6. issue 6. 2007-01-18. PMID:16702982. |
nicotine increases serotonin release in the brain and symptoms of nicotine withdrawal may be modulated by diminished serotonergic neurotransmission. |
2007-01-18 |
2023-08-12 |
human |
| Rebeca Martínez-Turrillas, Sonia Moyano, Joaquín Del Río, Diana Frechill. Differential effects of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") on BDNF mRNA expression in rat frontal cortex and hippocampus. Neuroscience letters. vol 402. issue 1-2. 2007-01-16. PMID:16644117. |
the serotonergic neurotoxin 3,4-methylenedioxymethamphetamine (mdma, "ecstasy") produces rapid serotonin (5-ht) depletion in different areas of the forebrain after acute administration to rats and other animal species. |
2007-01-16 |
2023-08-12 |
rat |