| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Agneta Ekman, Charlotta Sundblad-Elverfors, Mikael Landén, Tomas Eriksson, Elias Eriksso. Low density and high affinity of platelet [3H]paroxetine binding in women with bulimia nervosa. Psychiatry research. vol 142. issue 2-3. 2007-01-12. PMID:16690136. |
as an indirect measure of brain serotonergic activity, the binding of tritiated ligands to platelet serotonin transporters has been studied in bulimia nervosa as well as in other putatively serotonin-related psychiatric disorders. |
2007-01-12 |
2023-08-12 |
Not clear |
| George I Papakostas, Maurizio Fav. A metaanalysis of clinical trials comparing moclobemide with selective serotonin reuptake inhibitors for the treatment of major depressive disorder. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 51. issue 12. 2007-01-10. PMID:17168253. |
to compare response rates among patients with major depressive disorder (mdd) treated with either moclobemide, an antidepressant thought to simultaneously enhance both noradrenergic and serotonergic neurotransmission, or selective serotonin reuptake inhibitors (ssris). |
2007-01-10 |
2023-08-12 |
Not clear |
| Tao Xie, Liqiong Tong, Michael W McLane, George Hatzidimitriou, Jie Yuan, Una McCann, George Ricaurt. Loss of serotonin transporter protein after MDMA and other ring-substituted amphetamines. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 12. 2007-01-05. PMID:16452989. |
in the same animals, tryptophan hydroxylase (tph)-ir axon density was comparably reduced, indicating that serotonergic deficits after substituted amphetamines differ from those in sert-null animals, which have normal tph levels but, in the absence of sert, develop apparent neuroadaptive changes in 5-ht metabolism. |
2007-01-05 |
2023-08-12 |
Not clear |
| Tao Xie, Liqiong Tong, Michael W McLane, George Hatzidimitriou, Jie Yuan, Una McCann, George Ricaurt. Loss of serotonin transporter protein after MDMA and other ring-substituted amphetamines. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 12. 2007-01-05. PMID:16452989. |
together, these results suggest that lasting serotonergic deficits after mdma and related drugs are unlikely to represent neuroadaptive metabolic responses to changes in sert trafficking, and favor the view that substituted amphetamines have the potential to produce a distal axotomy of brain 5-ht neurons. |
2007-01-05 |
2023-08-12 |
Not clear |
| Fuad Lechin, Bertha van der Dij. Central nervous system circuitry and peripheral neural sympathetic activity responsible for essential hypertension. Current neurovascular research. vol 3. issue 4. 2007-01-05. PMID:17109626. |
we postulated that eh depends on the predominance of the binomial a5 noradrenergic (na) nucleus + median raphe serotonergic (5-ht) nucleus over the (a6)-na + dorsal raphe-5ht nuclei. |
2007-01-05 |
2023-08-12 |
Not clear |
| G Soydan, E Tekes, M Tunce. Investigation of serotonin receptors in the isolated penile bulb of rats. International journal of impotence research. vol 18. issue 6. 2007-01-04. PMID:16528294. |
these results suggest the existence of alpha(1)-adrenergic, 5-ht(1a) and 5-ht(2a) serotonergic receptors in the penile bulb of rats, which are responsible for 5-ht-induced contraction. |
2007-01-04 |
2023-08-12 |
rat |
| G Soydan, E Tekes, M Tunce. Investigation of serotonin receptors in the isolated penile bulb of rats. International journal of impotence research. vol 18. issue 6. 2007-01-04. PMID:16528294. |
additionally, a serotonergic receptor resembling a 5-ht(4)-type plays a role in the relaxation. |
2007-01-04 |
2023-08-12 |
rat |
| Stéphane Marinesco, Nimalee Wickremasinghe, Thomas J Care. Regulation of behavioral and synaptic plasticity by serotonin release within local modulatory fields in the CNS of Aplysia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 49. 2006-12-29. PMID:17151271. |
in aplysia, serotonergic neurons are widely activated during sensitization training, but the effects of exogenous serotonin (5-ht) on reflex circuits vary, inducing short- or long-term synaptic facilitation or synaptic inhibition, depending on the site of application. |
2006-12-29 |
2023-08-12 |
aplysia |
| Ashwin A Patkar, Paolo Mannelli, Kevin P Hill, Kathleen Peindl, Chi-Un Pae, Tong H Le. Relationship of prolactin response to meta-chlorophenylpiperazine with severity of drug use in cocaine dependence. Human psychopharmacology. vol 21. issue 6. 2006-12-22. PMID:16915581. |
serotonergic (5-ht) mechanisms appear to mediate central effects of cocaine. |
2006-12-22 |
2023-08-12 |
Not clear |
| Enza Palazzo, Vito de Novellis, Stefania Petrosino, Ida Marabese, Daniela Vita, Catia Giordano, Vincenzo Di Marzo, Giuseppe Salvatore Mangoni, Francesco Rossi, Sabatino Maion. Neuropathic pain and the endocannabinoid system in the dorsal raphe: pharmacological treatment and interactions with the serotonergic system. The European journal of neuroscience. vol 24. issue 7. 2006-12-21. PMID:17040473. |
furthermore, as well as thermal and mechanical hyperalgesia, cci caused serotonergic hyperactivity (as shown by the increase of basal activity of serotonergic neurones, extracellular serotonin levels and expression of 5-ht1a receptor gene). |
2006-12-21 |
2023-08-12 |
rat |
| Motoko Honda, Mitsuo Tanabe, Hideki On. Spinal cord injury-specific depression of monosynaptic spinal reflex transmission by l-5-hydroxytryptophan results from loss of the 5-HT uptake system and not 5-HT receptor supersensitivity. Experimental neurology. vol 202. issue 1. 2006-12-20. PMID:16806182. |
we studied changes in the spinal segmental reflex and serotonergic (5-ht) responses in rats after spinal cord injury (sci) produced by the weight-dropping method at the t8 level. |
2006-12-20 |
2023-08-12 |
rat |
| René Hummerich, Oliver Schulze, Thomas Rädler, Pal Mikecz, Matthias Reimold, Winfried Brenner, Malte Clausen, Patrick Schloss, Ralph Bucher. Inhibition of serotonin transport by (+)McN5652 is noncompetitive. Nuclear medicine and biology. vol 33. issue 3. 2006-12-18. PMID:16631080. |
imaging of the serotonergic innervation of the brain using positron emission tomography (pet) with the serotonin transporter (sert) ligand [11c] (+)mcn5652 might be affected by serotonin in the synaptic cleft if there is relevant interaction between [11c] (+)mcn5652 and serotonin at the sert. |
2006-12-18 |
2023-08-12 |
Not clear |
| Elisabeth Friess, Tania Kuempfel, Sieglinde Modell, Juliane Winkelmann, Florian Holsboer, Marcus Ising, Claudia Trenkwalde. Paroxetine treatment improves motor symptoms in patients with multiple system atrophy. Parkinsonism & related disorders. vol 12. issue 7. 2006-12-15. PMID:16769235. |
in view of the putative role of serotonergic neurotransmission in basal ganglia circuitry we investigated the effects of paroxetine (pxt) as a selective serotonin reuptake inhibitor (ssri) on the motor performance in n=19 patients clinically diagnosed as msa using a double-blind placebo-controlled randomized study design. |
2006-12-15 |
2023-08-12 |
Not clear |
| Meg Van Bogaert, Ronald Oosting, Miklos Toth, Lucianne Groenink, Ruud van Oorschot, Berend Olivie. Effects of genetic background and null mutation of 5-HT1A receptors on basal and stress-induced body temperature: modulation by serotonergic and GABAA-ergic drugs. European journal of pharmacology. vol 550. issue 1-3. 2006-12-15. PMID:17022970. |
serotonergic drugs alter these responses and here, we studied the role of 5-ht(1a) receptors in stress-induced hyperthermia by using 5-ht(1a) receptor knockout mice. |
2006-12-15 |
2023-08-12 |
mouse |
| K Audenaert, K Peremans, I Goethals, C van Heeringe. Functional imaging, serotonin and the suicidal brain. Acta neurologica Belgica. vol 106. issue 3. 2006-12-12. PMID:17091615. |
the involvement of the serotonergic system in the pathophysiology of suicidal behaviour has been established through indirect and direct research on serotonin and its metabolites and on serotonin transporters and receptors. |
2006-12-12 |
2023-08-12 |
Not clear |
| Nashat Abumaria, Rafal Rygula, Ursula Havemann-Reinecke, Eckart Rüther, Walter Bodemer, Christian Roos, Gabriele Flügg. Identification of genes regulated by chronic social stress in the rat dorsal raphe nucleus. Cellular and molecular neurobiology. vol 26. issue 2. 2006-12-11. PMID:16763781. |
changes in the serotonergic (5-ht) system are suspected to play a role in stress-induced neuropathologies and neurochemical measures indicate that serotonergic neurons in the dorsal raphe nucleus (drn) are activated during stress. |
2006-12-11 |
2023-08-12 |
rat |
| Laura M Hurle. Different serotonin receptor agonists have distinct effects on sound-evoked responses in inferior colliculus. Journal of neurophysiology. vol 96. issue 5. 2006-12-06. PMID:16870843. |
to determine whether activation of different types of serotonin receptors is a source of the variability in serotonergic effects, four selective agonists of serotonin receptors in the serotonin (5-ht) 1 and 5-ht2 families were iontophoretically applied to ic neurons, which were monitored for changes in their responses to auditory stimuli. |
2006-12-06 |
2023-08-12 |
Not clear |
| Kyoko Nishi, Dorotea Mück-Seler, Shu Hasegawa, Arata Watanabe, Mirko Diksi. Acute effects of moclobemide and deprenyl on 5-HT synthesis rates in the rat brain: An autoradiographic study. Brain research bulletin. vol 70. issue 4-6. 2006-12-05. PMID:17027772. |
the mechanism(s) of mao inhibitors' action on 5-ht synthesis in the raphe nuclei are probably related to an increase in the extraneuronal 5-ht concentration and also to the interaction between the serotonergic and catecholaminergic neurons. |
2006-12-05 |
2023-08-12 |
rat |
| Nicola Antonio Colabufo, Francesco Berardi, Roberto Perrone, Simona Rapposelli, Maria Digiacomo, Aldo Balsam. Arylmethyloxyphenyl derivatives: small molecules displaying P-glycoprotein inhibition. Journal of medicinal chemistry. vol 49. issue 22. 2006-12-05. PMID:17064079. |
some arylmethyloxyphenyl derivatives were prepared as simplified structures of analogous arylpiperazines with high affinity toward dopaminergic d(2) and serotonergic 5-ht(1a) receptors and inhibiting p-glycoprotein (p-gp). |
2006-12-05 |
2023-08-12 |
Not clear |
| M Metzger, L R G Britto, C A B Toled. Monoaminergic markers in the optic tectum of the domestic chick. Neuroscience. vol 141. issue 4. 2006-12-04. PMID:16781819. |
as a prerequisite to understand a possible functional role of the monoaminergic neurotransmitters, the serotonergic, noradrenergic, and dopaminergic innervation of the optic tectum as well as the distribution of serotonin 2a receptors, the dopamine- and camp-regulated phosphoprotein darpp-32 and calbindin d-28k was studied in domestic chicks by immunohistochemical techniques. |
2006-12-04 |
2023-08-12 |
chicken |