| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ester Aso, Thibault Renoir, Guadalupe Mengod, Catherine Ledent, Michel Hamon, Rafael Maldonado, Laurence Lanfumey, Olga Valverd. Lack of CB1 receptor activity impairs serotonergic negative feedback. Journal of neurochemistry. vol 109. issue 3. 2009-06-09. PMID:19302195. |
these results reveal that the lack of cb(1) receptor induces a facilitation of the activity of serotonergic neurons in the drn by altering different components of the 5-ht feedback as well as an increase in 5-ht extracellular levels in the prefrontal cortex in mice. |
2009-06-09 |
2023-08-12 |
mouse |
| E Martínez-García, B García-Iglesias, J A Terró. Effect of central serotonin depletion on 5-HT receptor-mediated vasomotor responses in the middle meningeal artery of anaesthetized rats. Autonomic & autacoid pharmacology. vol 29. issue 1-2. 2009-06-08. PMID:19302555. |
1 it has been hypothesized that craniovascular 5-ht receptors mediating dilatation of cranial vessels undergo sensitization on decreased serotonergic transmission in migraine. |
2009-06-08 |
2023-08-12 |
rat |
| Aleksandra Rajewska-Rager, Monika Dmitrzak-Weglarz, Paweł Kapelski, Maria Skibińska, Magdalena Kaczmarkiewicz-Fass, Joanna Hause. [Association between polymorphisms of ins/del in the 5-HTT gene and T102C in the 5HTR2A gene and the drug response for escitalopram and nortriptyline in depressed patients]. Psychiatria polska. vol 42. issue 6. 2009-06-04. PMID:19441667. |
the role of the serotonin receptor 5ht2a and serotonin transporter 5httlpr polymorphisms was suggested in the pathogenesis of depression and the therapeutic response to serotonergic drugs. |
2009-06-04 |
2023-08-12 |
Not clear |
| Yehonala Gudlowski, Seza Ozgürdal, Henning Witthaus, Jürgen Gallinat, Marta Hauser, Christine Winter, Idun Uhl, Andreas Heinz, Georg Jucke. Serotonergic dysfunction in the prodromal, first-episode and chronic course of schizophrenia as assessed by the loudness dependence of auditory evoked activity. Schizophrenia research. vol 109. issue 1-3. 2009-06-03. PMID:19268544. |
recent studies revealing evidence of increased serotonergic neurotransmission in schizophrenia has generated substantial interest in the role of serotonin in its pathophysiology. |
2009-06-03 |
2023-08-12 |
human |
| Chandra C Cardoso, Kelly R Lobato, Ricardo W Binfaré, Priscilla K Ferreira, Angelo O Rosa, Adair Roberto S Santos, Ana Lúcia S Rodrigue. Evidence for the involvement of the monoaminergic system in the antidepressant-like effect of magnesium. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 2. 2009-06-02. PMID:19059299. |
moreover, the administration of sub-effective doses of fluoxetine (10 mg/kg, i.p., serotonin reuptake inhibitor), imipramine (5 mg/kg, i.p., a mixed serotonergic noradrenergic reuptake inhibitor), bupropion (1 mg/kg, i.p., dopamine reuptake inhibitor) was able to potentiate the action of sub-effective doses of magnesium chloride. |
2009-06-02 |
2023-08-12 |
mouse |
| Chandra C Cardoso, Kelly R Lobato, Ricardo W Binfaré, Priscilla K Ferreira, Angelo O Rosa, Adair Roberto S Santos, Ana Lúcia S Rodrigue. Evidence for the involvement of the monoaminergic system in the antidepressant-like effect of magnesium. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 2. 2009-06-02. PMID:19059299. |
in conclusion, the present study provides evidence indicating that the antidepressant-like effect of magnesium in the fst is dependent on its interaction with the serotonergic (5-ht(1a) and 5-ht(2a/2c) receptors), noradrenergic (alpha(1)- and alpha(2)- receptors) and dopaminergic (dopamine d(1) and d(2) receptors) systems. |
2009-06-02 |
2023-08-12 |
mouse |
| Renato Leonardo Freitas, Célio Marcos dos Reis Ferreira, Maria Angélica Castiblanco Urbina, Andrés Uribe Mariño, Andressa Daiane Carvalho, Giuseppe Butera, Ana Maria de Oliveira, Norberto Cysne Coimbr. 5-HT1A/1B, 5-HT6, and 5-HT7 serotonergic receptors recruitment in tonic-clonic seizure-induced antinociception: role of dorsal raphe nucleus. Experimental neurology. vol 217. issue 1. 2009-05-26. PMID:19416688. |
the present work investigated the involvement of 5-ht(1a/1b), 5-ht(6), and 5-ht(7) serotonergic receptors through peripheral pretreatment with methiothepin at doses of 0.5, 1.0, 2.0 and 3.0 mg/kg in the organization of the post-ictal antinociception elicited by pharmacologically (with pentylenetetrazole at 64 mg/kg)-induced tonic-clonic seizures. |
2009-05-26 |
2023-08-12 |
Not clear |
| Renato Leonardo Freitas, Célio Marcos dos Reis Ferreira, Maria Angélica Castiblanco Urbina, Andrés Uribe Mariño, Andressa Daiane Carvalho, Giuseppe Butera, Ana Maria de Oliveira, Norberto Cysne Coimbr. 5-HT1A/1B, 5-HT6, and 5-HT7 serotonergic receptors recruitment in tonic-clonic seizure-induced antinociception: role of dorsal raphe nucleus. Experimental neurology. vol 217. issue 1. 2009-05-26. PMID:19416688. |
however, when the same 5-hydroxytryptamine receptors antagonist was microinjected (at 1.0, 3.0 and 5.0 microg/0.2 microl) in the dorsal raphe nucleus, a mesencephalic structure rich in serotonergic neurons and 5-ht receptors, the post-ictal hypo-analgesia was consistently antagonized. |
2009-05-26 |
2023-08-12 |
Not clear |
| Renato Leonardo Freitas, Célio Marcos dos Reis Ferreira, Maria Angélica Castiblanco Urbina, Andrés Uribe Mariño, Andressa Daiane Carvalho, Giuseppe Butera, Ana Maria de Oliveira, Norberto Cysne Coimbr. 5-HT1A/1B, 5-HT6, and 5-HT7 serotonergic receptors recruitment in tonic-clonic seizure-induced antinociception: role of dorsal raphe nucleus. Experimental neurology. vol 217. issue 1. 2009-05-26. PMID:19416688. |
the present findings suggest a dual effect of methiothepin, characterized by a disinhibitory effect on the post-ictal antinociception when peripherally administered (possibly due to an antagonism of pre-synaptic 5-ht(1a) serotonergic autoreceptors in the pain endogenous inhibitory system) and an inhibitory effect (possibly due to a drn post-synaptic 5-ht(1b), 5-ht(6), and 5-ht(7) serotonergic receptors blockade) when centrally administered. |
2009-05-26 |
2023-08-12 |
Not clear |
| Vesna Hercigonja Novkovic, Vlasta Rudan, Nela Pivac, Gordana Nedic, Dorotea Muck-Sele. Platelet serotonin concentration in children with attention-deficit/hyperactivity disorder. Neuropsychobiology. vol 59. issue 1. 2009-05-22. PMID:19221444. |
the neurobiology of adhd is still not clear, but is assumed to be related to disturbances in catecholaminergic and serotonergic (5-hydroxytryptamine, 5-ht) systems. |
2009-05-22 |
2023-08-12 |
Not clear |
| Richard B Rothman, Christina M Dersch, Subramaniam Ananthan, John S Partill. Studies of the biogenic amine transporters. 13. Identification of "agonist" and "antagonist" allosteric modulators of amphetamine-induced dopamine release. The Journal of pharmacology and experimental therapeutics. vol 329. issue 2. 2009-05-22. PMID:19244097. |
sori-9804 and sori-20040 did not attenuate d-amphetamine-induced release of [(3)h]5-hydroxytryptamine from serotonergic, or [(3)h]mpp(+) from noradrenergic, nerve terminals. |
2009-05-22 |
2023-08-12 |
Not clear |
| Francis Rodriguez Bambico, Nhu-Tram Nguyen, Gabriella Gobb. Decline in serotonergic firing activity and desensitization of 5-HT1A autoreceptors after chronic unpredictable stress. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 19. issue 3. 2009-05-20. PMID:19147333. |
chronic stressful life events are risk factors for contracting depression, the pathophysiology of which is strongly associated with impairments in serotonergic (5-ht) neurotransmission. |
2009-05-20 |
2023-08-12 |
rat |
| M E Pum, J P Huston, C P Mülle. The role of cortical serotonin in anxiety and locomotor activity in Wistar rats. Behavioral neuroscience. vol 123. issue 2. 2009-05-18. PMID:19331468. |
the present series of studies used local injections of the serotonergic neurotoxin, 5,7-dihydroxytryptamine (5,7-dht), into the medial prefrontal cortex (mpfc), entorhinal cortex (ec), or occipital cortex (occc) of rats to chronically reduce 5-ht neurotransmission in these brain areas. |
2009-05-18 |
2023-08-12 |
rat |
| Jan Kalbitzer, Vibe G Frokjaer, David Erritzoe, Claus Svarer, Paul Cumming, Finn A Nielsen, Sayed H Hashemi, William F C Baaré, Jacob Madsen, Steen G Hasselbalch, Morten L Kringelbach, Erik L Mortensen, Gitte M Knudse. The personality trait openness is related to cerebral 5-HTT levels. NeuroImage. vol 45. issue 2. 2009-05-13. PMID:19135154. |
we hypothesized that the personality trait has an association with a biomarker of serotonergic transmission, the plasma membrane serotonin transporter (5-htt). |
2009-05-13 |
2023-08-12 |
human |
| Samuel Pombo, Pilar de Quinhones Levy, Manuel Bicho, António Barbosa, Fátima Ismail, Neves Cardos. [Association of the functional serotonin transporter promoter polymorphism (5-HTTLPR) with externalizing and internalizing aggressivity and alcohol abuse]. Acta medica portuguesa. vol 21. issue 6. 2009-05-05. PMID:19331786. |
the pathogenesis of alcoholism and anti-social behaviour has been connected to serotonergic system dysfunction, given support to examine the association with 44-basepair insertion/deletion polymorphism of serotonin gene transporter (5-htt). |
2009-05-05 |
2023-08-12 |
human |
| René Hurlemann, Thomas E Schlaepfer, Andreas Matusch, Harald Reich, Nadim J Shah, Karl Zilles, Wolfgang Maier, Andreas Baue. Reduced 5-HT(2A) receptor signaling following selective bilateral amygdala damage. Social cognitive and affective neuroscience. vol 4. issue 1. 2009-05-01. PMID:19015089. |
neurobiological evidence implicates the amygdala as well as serotonergic (serotonin, 5-ht) signaling via postsynaptic 5-ht(2a) receptors as essential substrates of anxiety behaviors. |
2009-05-01 |
2023-08-12 |
human |
| Kheira Benzekhroufa, Beihui Liu, Feige Tang, Anja G Teschemacher, Sergey Kasparo. Adenoviral vectors for highly selective gene expression in central serotonergic neurons reveal quantal characteristics of serotonin release in the rat brain. BMC biotechnology. vol 9. 2009-05-01. PMID:19298646. |
adenoviral vectors for highly selective gene expression in central serotonergic neurons reveal quantal characteristics of serotonin release in the rat brain. |
2009-05-01 |
2023-08-12 |
rat |
| Kheira Benzekhroufa, Beihui Liu, Feige Tang, Anja G Teschemacher, Sergey Kasparo. Adenoviral vectors for highly selective gene expression in central serotonergic neurons reveal quantal characteristics of serotonin release in the rat brain. BMC biotechnology. vol 9. 2009-05-01. PMID:19298646. |
5-hydroxytryptamine (5 ht, serotonin) is one of the key neuromodulators in mammalian brain, but many fundamental properties of serotonergic neurones and 5 ht release remain unknown. |
2009-05-01 |
2023-08-12 |
rat |
| Stephan C Bischoff, Reiner Mailer, Oliver Pabst, Gisela Weier, Wanda Sedlik, Zhishan Li, Jason J Chen, Dennis L Murphy, Michael D Gersho. Role of serotonin in intestinal inflammation: knockout of serotonin reuptake transporter exacerbates 2,4,6-trinitrobenzene sulfonic acid colitis in mice. American journal of physiology. Gastrointestinal and liver physiology. vol 296. issue 3. 2009-04-28. PMID:19095763. |
we tested the hypotheses that 5-ht plays a role in regulating intestinal inflammation and that the potentiation of serotonergic signaling that results from sert deletion is proinflammatory. |
2009-04-28 |
2023-08-12 |
mouse |
| Paul L Soto, Jonathan L Kat. Fluoxetine does not alter the ability of dopamine D(1)- and D(2)-like agonists to substitute for cocaine in squirrel monkeys. Pharmacology, biochemistry, and behavior. vol 92. issue 2. 2009-04-27. PMID:19101584. |
an interaction between increased serotonergic and dopaminergic actions produced by blockade of serotonin and dopamine reuptake, is one possible mechanism for the enhancement. |
2009-04-27 |
2023-08-12 |
monkey |