| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Sutovská, G Nosálová, J Sutovský, S Franová, L Prisenznáková, P Cape. Possible mechanisms of dose-dependent cough suppressive effect of Althaea officinalis rhamnogalacturonan in guinea pigs test system. International journal of biological macromolecules. vol 45. issue 1. 2009-08-10. PMID:19447256. |
from this point of view it seems that the cough suppression effect of the polymer is associated with the serotonergic 5-ht(2) receptor's function. |
2009-08-10 |
2023-08-12 |
Not clear |
| Elodie Pradines, Damien Loubet, Sophie Mouillet-Richard, Philippe Manivet, Jean-Marie Launay, Odile Kellermann, Benoît Schneide. Cellular prion protein coupling to TACE-dependent TNF-alpha shedding controls neurotransmitter catabolism in neuronal cells. Journal of neurochemistry. vol 110. issue 3. 2009-08-07. PMID:19457070. |
by taking advantage of a neuroectodermal cell line (1c11) endowed with the capacity to differentiate into serotonergic (1c11(5-ht)) or noradrenergic (1c11(ne)) neurons, we assessed the contribution of prp(c) to bioaminergic cell functions. |
2009-08-07 |
2023-08-12 |
Not clear |
| Xenia Borue, Stephanie Cooper, Jay Hirsh, Barry Condron, B Jill Vento. Quantitative evaluation of serotonin release and clearance in Drosophila. Journal of neuroscience methods. vol 179. issue 2. 2009-08-04. PMID:19428541. |
this study shows that the dynamics of serotonin release and reuptake in drosophila are analogous to those in mammals, making this simple organism more useful for the study of the basic physiological mechanisms of serotonergic signaling. |
2009-08-04 |
2023-08-12 |
drosophila_melanogaster |
| Andrew K Evans, Jasper L T Heerkens, Christopher A Lowr. Acoustic stimulation in vivo and corticotropin-releasing factor in vitro increase tryptophan hydroxylase activity in the rat caudal dorsal raphe nucleus. Neuroscience letters. vol 455. issue 1. 2009-07-31. PMID:19429102. |
exposure of rats to unpredictable loud sound pulses increases activity of the rate-limiting enzyme for serotonin synthesis, tryptophan hydroxylase (tph), in the median raphe nucleus (mnr) and a mesolimbocortical serotonergic system. |
2009-07-31 |
2023-08-12 |
rat |
| John J Dougherty, Robert A Nichol. Cross-regulation between colocalized nicotinic acetylcholine and 5-HT3 serotonin receptors on presynaptic nerve terminals. Acta pharmacologica Sinica. vol 30. issue 6. 2009-07-31. PMID:19498419. |
the present study was aimed at addressing whether nicotinic acetylcholine receptors and 5-ht(3) serotonin receptors interact on the same presynaptic terminal, suggesting a convergence of cholinergic and serotonergic regulation. |
2009-07-31 |
2023-08-12 |
Not clear |
| Elaine L Bearer, Xiaowei Zhang, Davit Janvelyan, Benoit Boulat, Russell E Jacob. Reward circuitry is perturbed in the absence of the serotonin transporter. NeuroImage. vol 46. issue 4. 2009-07-29. PMID:19306930. |
the serotonin transporter (sert) modulates the entire serotonergic system in the brain and influences both the dopaminergic and norepinephrinergic systems. |
2009-07-29 |
2023-08-12 |
mouse |
| Fu-Quan Huo, Tao Chen, Bo-Chang Lv, Jing Wang, Ting Zhang, Chao-Ling Qu, Yun-Qing Li, Jing-Shi Tan. Synaptic connections between GABAergic elements and serotonergic terminals or projecting neurons in the ventrolateral orbital cortex. Cerebral cortex (New York, N.Y. : 1991). vol 19. issue 6. 2009-07-28. PMID:18980950. |
results indicate that the majority (93%) of gabaergic neurons in the vlo also express the 5-ht(1a) (5-hydroxytryptamine 1a) receptor, and serotonergic terminals originating from the dr nucleus made symmetrical synapses with gabaergic neuronal cell bodies and dendrites within the vlo. |
2009-07-28 |
2023-08-12 |
Not clear |
| Khanh Q Nguyen, Yoshihiro Tohyama, Arata Watanabe, Shu Hasegawa, Ivan Skelin, Mirko Diksi. Acute effects of combining citalopram and pindolol on regional brain serotonin synthesis in sham operated and olfactory bulbectomized rats. Neurochemistry international. vol 54. issue 3-4. 2009-07-28. PMID:19073228. |
the underlying mechanism is thought to involve acute unrestricting of 5-ht release and, consequently, relatively enhanced 5-ht turnover throughout the forebrain serotonergic networks. |
2009-07-28 |
2023-08-12 |
human |
| Khanh Q Nguyen, Yoshihiro Tohyama, Arata Watanabe, Shu Hasegawa, Ivan Skelin, Mirko Diksi. Acute effects of combining citalopram and pindolol on regional brain serotonin synthesis in sham operated and olfactory bulbectomized rats. Neurochemistry international. vol 54. issue 3-4. 2009-07-28. PMID:19073228. |
the effect of this combination on 5-ht turnover in sham operated or obx rats can be assessed at the level of 5-ht synthesis, a very important presynaptic step in serotonergic neurotransmission, using the alpha-[(14)c]methyl-l-tryptophan autoradiography method. |
2009-07-28 |
2023-08-12 |
human |
| Khanh Q Nguyen, Yoshihiro Tohyama, Arata Watanabe, Shu Hasegawa, Ivan Skelin, Mirko Diksi. Acute effects of combining citalopram and pindolol on regional brain serotonin synthesis in sham operated and olfactory bulbectomized rats. Neurochemistry international. vol 54. issue 3-4. 2009-07-28. PMID:19073228. |
pindolol acceleration and augmentation of ssri antidepressant therapy for human depression may be mediated by attenuation of 5-ht(1a/b) autoreceptor feedback, permitting unhindered ssri effects on serotonergic terminals. |
2009-07-28 |
2023-08-12 |
human |
| Kyoko Nishi, Kazuya Kanemaru, Shu Hasegawa, Arata Watanabe, Mirko Diksi. Both acute and chronic buspirone treatments have different effects on regional 5-HT synthesis in Flinders Sensitive Line rats (a rat model of depression) than in control rats. Neurochemistry international. vol 54. issue 3-4. 2009-07-28. PMID:19084042. |
the data suggest that with respect to 5-ht synthesis, frl rats differ from spd rats (a natural control; normal rats) and, as such, indicate that when the effects related to the serotonergic system (e.g., influence of serotonergic drugs) are studied in the fsl rats and compared to those in the frl rats, any conclusions drawn may not reflect differences relative to a normal rat. |
2009-07-28 |
2023-08-12 |
rat |
| Thorsten Lau, Sandra Horschitz, Dusan Bartsch, Patrick Schlos. Monitoring mouse serotonin transporter internalization in stem cell-derived serotonergic neurons by confocal laser scanning microscopy. Neurochemistry international. vol 54. issue 3-4. 2009-07-28. PMID:19121357. |
monitoring mouse serotonin transporter internalization in stem cell-derived serotonergic neurons by confocal laser scanning microscopy. |
2009-07-28 |
2023-08-12 |
mouse |
| Thorsten Lau, Sandra Horschitz, Dusan Bartsch, Patrick Schlos. Monitoring mouse serotonin transporter internalization in stem cell-derived serotonergic neurons by confocal laser scanning microscopy. Neurochemistry international. vol 54. issue 3-4. 2009-07-28. PMID:19121357. |
in the central nervous system serotonergic neurotransmission is terminated by the rapid removal of serotonin (5-hydroxytryptamine, 5ht) out of the extra-cellular space back into the presynaptic neuron. |
2009-07-28 |
2023-08-12 |
mouse |
| Kyoko Nishi, Kazuya Kanemaru, Mirko Diksi. A genetic rat model of depression, Flinders sensitive line, has a lower density of 5-HT(1A) receptors, but a higher density of 5-HT(1B) receptors, compared to control rats. Neurochemistry international. vol 54. issue 5-6. 2009-07-28. PMID:19121358. |
deficiencies in brain serotonergic neurotransmission, which is in part associated with the alteration of brain serotonin (5-ht) receptors, have been proposed as part of a neurochemical imbalance in affective disorders, including depression. |
2009-07-28 |
2023-08-12 |
human |
| Kazuya Kanemaru, Kyoko Nishi, Shu Hasegawa, Mirko Diksi. Chronic citalopram treatment elevates serotonin synthesis in flinders sensitive and flinders resistant lines of rats, with no significant effect on Sprague-Dawley rats. Neurochemistry international. vol 54. issue 5-6. 2009-07-28. PMID:19418630. |
the influence of citalopram on regional 5-hydroxytryptamine (serotonin, 5-ht) synthesis, one of the most important presynaptic parameters of serotonergic neurotransmission, was studied. |
2009-07-28 |
2023-08-12 |
rat |
| Emil F Coccaro, Royce J Lee, Richard J Kavouss. A double-blind, randomized, placebo-controlled trial of fluoxetine in patients with intermittent explosive disorder. The Journal of clinical psychiatry. vol 70. issue 5. 2009-07-22. PMID:19389333. |
since central serotonergic (5-ht) system dysfunction is related to impulsive aggressive behavior, pharmacologic enhancement of 5-ht activity should reduce impulsive aggressive behavior in individuals with ied. |
2009-07-22 |
2023-08-12 |
Not clear |
| Manoj Kumar, Sanjeev K Kaushalya, Pierre Gressens, Sudipta Maiti, Shyamala Man. Optimized derivation and functional characterization of 5-HT neurons from human embryonic stem cells. Stem cells and development. vol 18. issue 4. 2009-07-20. PMID:18800863. |
the ability to study the characteristics of serotonin release from human serotonergic neurons is valuable both in terms of understanding disease pathology and in trying to understand how drugs that affect the serotonergic system alter neurotransmitter release. |
2009-07-20 |
2023-08-12 |
human |
| Manoj Kumar, Sanjeev K Kaushalya, Pierre Gressens, Sudipta Maiti, Shyamala Man. Optimized derivation and functional characterization of 5-HT neurons from human embryonic stem cells. Stem cells and development. vol 18. issue 4. 2009-07-20. PMID:18800863. |
these serotonergic neurons expressed both serotonin and the neuron-specific tryptophan hydroxylase enzyme. |
2009-07-20 |
2023-08-12 |
human |
| Myriam Ermonval, Daniel Petit, Aurélien Le Duc, Odile Kellermann, Paul-François Galle. Glycosylation-related genes are variably expressed depending on the differentiation state of a bioaminergic neuronal cell line: implication for the cellular prion protein. Glycoconjugate journal. vol 26. issue 4. 2009-07-20. PMID:18937066. |
using the 1c11 neuronal bioaminergic differentiation model and a glycomics approach, we show here a correlation between differential prp(c) n-glycosylations in 1c11(5-ht) serotonergic and 1c11(ne) noradrenergic cells compared to their 1c11 precursor cells and a variation of the glycogenome expression status in these cells. |
2009-07-20 |
2023-08-12 |
Not clear |
| Matthias M Herth, Markus Piel, Fabian Debus, Ulrich Schmitt, Hartmut Lüddens, Frank Rösc. Preliminary in vivo and ex vivo evaluation of the 5-HT2A imaging probe [(18)F]MH.MZ. Nuclear medicine and biology. vol 36. issue 4. 2009-07-20. PMID:19423013. |
the 5-ht(2a) receptor is one of the most interesting targets within the serotonergic system because it is involved in a number of important physiological processes and diseases. |
2009-07-20 |
2023-08-12 |
Not clear |