| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Marazziti, F Mungai, I Masala, S Baroni, L Vivarelli, F Ambrogi, M Catena Dell'Osso, G Consoli, G Massimetti, L Dell'Oss. Normalisation of immune cell imbalance after pharmacological treatments of patients suffering from obsessive-compulsive disorder. Journal of psychopharmacology (Oxford, England). vol 23. issue 5. 2009-09-14. PMID:18755814. |
the objective of this study was to examine the possible effects of 12 months of treatment with different serotonergic drugs, such as clomipramine and selective serotonin reuptake inhibitors (ssris) on peripheral immunological cells of 18 ocd patients. |
2009-09-14 |
2023-08-12 |
human |
| Ahmet Dogrul, Michael H Ossipov, Frank Porrec. Differential mediation of descending pain facilitation and inhibition by spinal 5HT-3 and 5HT-7 receptors. Brain research. vol 1280. 2009-09-14. PMID:19427839. |
noxious stimuli can activate serotonergic neurons in the rvm and accelerate the turnover of 5-ht in the spinal cord. |
2009-09-14 |
2023-08-12 |
rat |
| Ahmet Dogrul, Michael H Ossipov, Frank Porrec. Differential mediation of descending pain facilitation and inhibition by spinal 5HT-3 and 5HT-7 receptors. Brain research. vol 1280. 2009-09-14. PMID:19427839. |
while numerous studies suggest a bidirectional role for serotonergic transmission at the spinal level, the subtypes of the 5-ht receptors that are associated with descending facilitation or inhibition have not been clearly determined. |
2009-09-14 |
2023-08-12 |
rat |
| Jonathan A Oler, Andrew S Fox, Steven E Shelton, Bradley T Christian, Dhanabalan Murali, Terrence R Oakes, Richard J Davidson, Ned H Kali. Serotonin transporter availability in the amygdala and bed nucleus of the stria terminalis predicts anxious temperament and brain glucose metabolic activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 32. 2009-09-08. PMID:19675230. |
the serotonin transporter (5-htt) plays a critical role in regulating serotonergic neurotransmission and is implicated in the pathophysiology of anxiety and affective disorders. |
2009-09-08 |
2023-08-12 |
monkey |
| Chiung-Chun Huang, Ying-Ching Liang, Cheng-Che Lee, Mei-Ying Wu, Kuei-Sen Hs. Repeated cocaine administration decreases 5-HT(2A) receptor-mediated serotonergic enhancement of synaptic activity in rat medial prefrontal cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 8. 2009-09-02. PMID:19212317. |
repeated cocaine administration decreases 5-ht(2a) receptor-mediated serotonergic enhancement of synaptic activity in rat medial prefrontal cortex. |
2009-09-02 |
2023-08-12 |
rat |
| Chiung-Chun Huang, Ying-Ching Liang, Cheng-Che Lee, Mei-Ying Wu, Kuei-Sen Hs. Repeated cocaine administration decreases 5-HT(2A) receptor-mediated serotonergic enhancement of synaptic activity in rat medial prefrontal cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 8. 2009-09-02. PMID:19212317. |
the mpfc receives a dense serotonergic (5-hydroxytryptamine, 5-ht) innervation from raphe nuclei and 5-ht exerts complex actions on mpfc pyramidal neurons. |
2009-09-02 |
2023-08-12 |
rat |
| Felipe Corchs, David J Nutt, Sean Hood, Marcio Berni. Serotonin and sensitivity to trauma-related exposure in selective serotonin reuptake inhibitors-recovered posttraumatic stress disorder. Biological psychiatry. vol 66. issue 1. 2009-08-31. PMID:19268914. |
serotonergic (5ht) attenuation of stress sensitivity is postulated from ssris' effects in other anxiety disorders, and we studied this in ptsd. |
2009-08-31 |
2023-08-12 |
Not clear |
| John Chen, Barry G Condro. Drosophila serotonergic varicosities are not distributed in a regular manner. The Journal of comparative neurology. vol 515. issue 4. 2009-08-31. PMID:19459220. |
here we examine the spatial pattern of serotonergic varicosities, the synaptic sites of serotonin release in the central nervous system (cns). |
2009-08-31 |
2023-08-12 |
xenopus_laevis |
| Pablo Vázquez-Borsetti, Roser Cortés, Francesc Artiga. Pyramidal neurons in rat prefrontal cortex projecting to ventral tegmental area and dorsal raphe nucleus express 5-HT2A receptors. Cerebral cortex (New York, N.Y. : 1991). vol 19. issue 7. 2009-08-26. PMID:19029064. |
thus, 5-ht(2a) receptor activation/blockade in pfc may have downstream effects on dopaminergic and serotonergic systems via direct descending pathways. |
2009-08-26 |
2023-08-12 |
rat |
| M A Cooper, M S Grober, C R Nicholas, K L Huhma. Aggressive encounters alter the activation of serotonergic neurons and the expression of 5-HT1A mRNA in the hamster dorsal raphe nucleus. Neuroscience. vol 161. issue 3. 2009-08-24. PMID:19362123. |
serotonergic (5-ht) neurons in the dorsal raphe nucleus (drn) have been implicated in stress-induced changes in behavior. |
2009-08-24 |
2023-08-12 |
Not clear |
| Christopher A Lowry, Matthew W Hale, Kathleen A Burke, Kenneth J Renner, Frank L Moor. Fluoxetine potentiates the effects of corticotropin-releasing factor on locomotor activity and serotonergic systems in the roughskin newt, Taricha granulosa. Hormones and behavior. vol 56. issue 1. 2009-08-21. PMID:19409390. |
we hypothesized that this crf-induced increase in locomotor activity involves a central effect of crf on serotonergic neurons, based on known stimulatory actions of serotonin (5-hydroxytryptamine, 5-ht) on spinal motor neurons and the central pattern generator for locomotor activity in vertebrates. |
2009-08-21 |
2023-08-12 |
Not clear |
| Marc Cuesta, Daniel Clesse, Paul Pévet, Etienne Challe. New light on the serotonergic paradox in the rat circadian system. Journal of neurochemistry. vol 110. issue 1. 2009-08-21. PMID:19457131. |
serotonergic agonists and serotonin reuptake inhibitors (e.g., fluoxetine) have a non-photic influence (shifting effects during daytime and attenuation of photic resetting during nighttime) on hamsters' and mice' main clock. |
2009-08-21 |
2023-08-12 |
mouse |
| Dallas R Donohoe, Raymond A Jarvis, Kathrine Weeks, Eric J Aamodt, Donard S Dwye. Behavioral adaptation in C. elegans produced by antipsychotic drugs requires serotonin and is associated with calcium signaling and calcineurin inhibition. Neuroscience research. vol 64. issue 3. 2009-08-20. PMID:19447297. |
this rebound response is absent or diminished in mutant strains that lack tryptophan hydroxylase (tph-1) or the serotonin receptors ser-7 and ser-1, and is blocked by serotonin antagonists, which implicates serotonergic mechanisms in this adaptive response. |
2009-08-20 |
2023-08-12 |
caenorhabditis_elegans |
| Georgina Perez-Garcia, Alfredo Menese. Memory time-course: mRNA 5-HT1A and 5-HT7 receptors. Behavioural brain research. vol 202. issue 1. 2009-08-19. PMID:19447286. |
notably, high levels of efficient memory were maintained even when serotonergic tone, via either 5-ht(1a) or 5-ht(7) receptor, was down- or up-regulated. |
2009-08-19 |
2023-08-12 |
Not clear |
| Olga Dergacheva, Harriet Kamendi, Xin Wang, Ramon Manchon Pinol, Julie Frank, Heather Jameson, Christopher Gorini, David Mendelowit. The role of 5-HT3 and other excitatory receptors in central cardiorespiratory responses to hypoxia: implications for sudden infant death syndrome. Pediatric research. vol 65. issue 6. 2009-08-17. PMID:19247214. |
although brainstem serotonergic (5-ht) systems are involved in the protective responses to hypoxia, abnormalities of 5-ht function are strongly implicated in sids, and the neurochemical mechanisms by which 5-ht receptors influence brainstem cardiorespiratory responses to hypoxia remains unclear. |
2009-08-17 |
2023-08-12 |
Not clear |
| Arindam Dalal, Mrinal K Podda. Short-term erythrosine B-induced inhibition of the brain regional serotonergic activity suppresses motor activity (exploratory behavior) of young adult mammals. Pharmacology, biochemistry, and behavior. vol 92. issue 4. 2009-08-14. PMID:19264092. |
of erythrosine administration to young adult male rats reduced motor activity (ma) maximally at 2 h and brain regional (medulla-pons, hippocampus and hypothalamus) serotonergic activity (measuring steady-state levels of 5-ht and 5-hiaa, pargyline-induced 5-ht accumulation and 5-hiaa declination rate and 5-ht receptor binding) under similar experimental condition. |
2009-08-14 |
2023-08-12 |
rat |
| David Bräuer, Alexander Strobel, Tilman Hensch, Kersten Diers, Klaus-Peter Lesch, Burkhard Brock. Genetic variation of serotonin receptor function affects prepulse inhibition of the startle. Journal of neural transmission (Vienna, Austria : 1996). vol 116. issue 5. 2009-08-14. PMID:19352591. |
our results may indicate that a higher 5-htr2a expression together with a reduced 5-htr1a autoreceptor expression and consequently, elevated firing rates of serotonergic neurons results in elevated 5-htr2a activation by serotonin which could potently attenuate ppi. |
2009-08-14 |
2023-08-12 |
human |
| Christine Firk, C Rob Marku. Mood and cortisol responses following tryptophan-rich hydrolyzed protein and acute stress in healthy subjects with high and low cognitive reactivity to depression. Clinical nutrition (Edinburgh, Scotland). vol 28. issue 3. 2009-08-13. PMID:19345451. |
it is suggested that stress particularly in subjects with high cognitive reactivity (cr), a psychological vulnerability marker of depression, may increase or even induce serotonergic vulnerability, which in turn may lead to reduced serotonin (5-ht) function, decreased stress coping and an increased risk to develop depressive symptoms. |
2009-08-13 |
2023-08-12 |
human |
| Stephen J Kish, Paul S Fitzmaurice, Isabelle Boileau, Gregory A Schmunk, Lee-Cyn Ang, Yoshiaki Furukawa, Li-Jan Chang, Dennis J Wickham, Allan Sherwin, Junchao Ton. Brain serotonin transporter in human methamphetamine users. Psychopharmacology. vol 202. issue 4. 2009-08-11. PMID:18841348. |
however, animal data also indicate that ma can damage brain serotonin neurones, and it has been suggested that cognitive problems and aggression in ma users might be explained by serotonergic damage. |
2009-08-11 |
2023-08-12 |
human |
| Stefan Wüst, Robert Kumsta, Jens Treutlein, Josef Frank, Sonja Entringer, Thomas G Schulze, Marcella Rietsche. Sex-specific association between the 5-HTT gene-linked polymorphic region and basal cortisol secretion. Psychoneuroendocrinology. vol 34. issue 7. 2009-08-11. PMID:19249159. |
a key regulator of serotonergic neurotransmission is the serotonin transporter (5-htt) and a common 5htt gene promoter polymorphism, termed 5httlpr, is associated with phenotypes related to anxiety and depression. |
2009-08-11 |
2023-08-12 |
Not clear |