| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cristina Miguelez, Teresa Morera-Herreras, Maria Torrecilla, Jose A Ruiz-Ortega, Luisa Uged. Interaction between the 5-HT system and the basal ganglia: functional implication and therapeutic perspective in Parkinson's disease. Frontiers in neural circuits. vol 8. 2014-09-24. PMID:24672433. |
the largest population of serotonergic neurons is located in the midbrain, specifically in the raphe nuclei. |
2014-09-24 |
2023-08-12 |
Not clear |
| R C Drugan, P T Hibl, K J Kelly, K F Dady, M W Hale, C A Lowr. Prior cold water swim stress alters immobility in the forced swim test and associated activation of serotonergic neurons in the rat dorsal raphe nucleus. Neuroscience. vol 253. 2014-06-19. PMID:23999122. |
rats were transcardially perfused with fixative 2h following the onset of the swim on day 2 for analysis of c-fos expression in midbrain serotonergic neurons. |
2014-06-19 |
2023-08-12 |
rat |
| Tetsuji Terashima, Kenshu Shirakawa, Masao Maekawa, Naoki Furukawa, Shigeki Yamaguchi, Yuuichi Hor. Differential expression of NMDA receptors in serotonergic and/or GABAergic neurons in the midbrain periaqueductal gray of the mouse. Neuroscience letters. vol 528. issue 1. 2014-05-02. PMID:22975137. |
differential expression of nmda receptors in serotonergic and/or gabaergic neurons in the midbrain periaqueductal gray of the mouse. |
2014-05-02 |
2023-08-12 |
mouse |
| M R Williams, R Marsh, C D Macdonald, J Jain, R K B Pearce, S R Hirsch, O Ansorge, S M Gentleman, M Maie. Neuropathological changes in the nucleus basalis in schizophrenia. European archives of psychiatry and clinical neuroscience. vol 263. issue 6. 2014-03-21. PMID:23229688. |
the nucleus basalis is a collection of large cholinergic neurons in the basal forebrain receiving information from the midbrain and limbic system, projecting to the cortex and involved with attention, learning and memory, and receives regulation from serotonergic inputs. |
2014-03-21 |
2023-08-12 |
Not clear |
| Orna Issler, Roderick N Carter, Evan D Paul, Paul At Kelly, Henry J Olverman, Adi Neufeld-Cohen, Yael Kuperman, Christopher A Lowry, Jonathan R Seckl, Alon Chen, Pauline M Jamieso. Increased anxiety in corticotropin-releasing factor type 2 receptor-null mice requires recent acute stress exposure and is associated with dysregulated serotonergic activity in limbic brain areas. Biology of mood & anxiety disorders. vol 4. issue 1. 2014-03-12. PMID:24447313. |
they are abundant in the midbrain raphe nuclei, where they regulate serotonergic neuronal activity and have been demonstrated to mediate behavioural consequences of stress. |
2014-03-12 |
2023-08-12 |
mouse |
| Cynthia L Bethea, Kenny Phu, Arubala P Reddy, Judy L Camero. The effect of short moderate stress on the midbrain corticotropin-releasing factor system in a macaque model of functional hypothalamic amenorrhea. Fertility and sterility. vol 100. issue 4. 2014-03-11. PMID:23849846. |
to study the effect of moderate stress on corticotropin-releasing factor (crf) components in the serotonergic midbrain region in a monkey model of functional hypothalamic amenorrhea. |
2014-03-11 |
2023-08-12 |
monkey |
| Ul'yana A Boyarskikh, Natalya P Bondar, Maxim L Filipenko, Natalia N Kudryavtsev. Downregulation of serotonergic gene expression in the Raphe nuclei of the midbrain under chronic social defeat stress in male mice. Molecular neurobiology. vol 48. issue 1. 2014-02-12. PMID:23392607. |
downregulation of serotonergic gene expression in the raphe nuclei of the midbrain under chronic social defeat stress in male mice. |
2014-02-12 |
2023-08-12 |
mouse |
| Ul'yana A Boyarskikh, Natalya P Bondar, Maxim L Filipenko, Natalia N Kudryavtsev. Downregulation of serotonergic gene expression in the Raphe nuclei of the midbrain under chronic social defeat stress in male mice. Molecular neurobiology. vol 48. issue 1. 2014-02-12. PMID:23392607. |
the study aimed to analyze mrna levels of the serotonergic genes in the raphe nuclei of midbrain that may be associated with chronic social defeats consistently shown by male mice in special experimental settings. |
2014-02-12 |
2023-08-12 |
mouse |
| Lisa L Matragrano, Meredith M LeBlanc, Anjani Chitrapu, Zane E Blanton, Donna L Mane. Testosterone alters genomic responses to song and monoaminergic innervation of auditory areas in a seasonally breeding songbird. Developmental neurobiology. vol 73. issue 6. 2014-01-21. PMID:23362219. |
testosterone treatment reduced serotonergic fiber density in the auditory forebrain, thalamus, and midbrain, and although it increased the number of noradrenergic neurons detected in the locus coeruleus, it reduced noradrenergic fiber density in the auditory midbrain. |
2014-01-21 |
2023-08-12 |
Not clear |
| Hyo-Jin Jeong, Karen Lam, Vanessa A Mitchell, Christopher W Vaugha. Serotonergic modulation of neuronal activity in rat midbrain periaqueductal gray. Journal of neurophysiology. vol 109. issue 11. 2013-12-16. PMID:23515792. |
serotonergic modulation of neuronal activity in rat midbrain periaqueductal gray. |
2013-12-16 |
2023-08-12 |
rat |
| L M Neckers, L Bertilsson, E Cost. The action of fenfluramine andp-chloramphetamine on serotonergic mechanisms: A comparative study in rat brain nuclei. Neurochemical research. vol 1. issue 1. 2013-11-26. PMID:24271241. |
other reports have shown that a single injection of fenfluramine or pca causes cytopathological changes in a serotonergic midbrain nucleus which was termed b9 by dahlstrom and fuxe (1). |
2013-11-26 |
2023-08-12 |
rat |
| Nina C Donner, Christopher A Lowr. Sex differences in anxiety and emotional behavior. Pflugers Archiv : European journal of physiology. vol 465. issue 5. 2013-11-14. PMID:23588380. |
we discuss how these serotonergic circuits may be controlled by reproductive steroid hormone-dependent modulation of crfr1 and crfr2 expression in the midbrain dorsal raphe nucleus and by estrous stage-dependent alterations of γ-aminobutyric acid (gabaergic) neurotransmission in the periaqueductal gray, ultimately leading to sex differences in emotional behavior. |
2013-11-14 |
2023-08-12 |
human |
| Tanja Hochstrasser, Lindsay A Hohsfield, Barbara Sperner-Unterweger, Christian Humpe. β-Amyloid induced effects on cholinergic, serotonergic, and dopaminergic neurons is differentially counteracted by anti-inflammatory drugs. Journal of neuroscience research. vol 91. issue 1. 2013-07-18. PMID:22996751. |
the aim of the present study was to investigate the effects of aβ(1-42) on cholinergic neurons of the nucleus basalis of meynert (which degenerate in ad), on serotonergic neurons of the dorsal raphe nucleus (which play a role in depression), and on dopaminergic neurons of the ventral mesencephalon (which degenerate in pd) in rat organotypic brain slices. |
2013-07-18 |
2023-08-12 |
rat |
| F G Graef. New perspective on the pathophysiology of panic: merging serotonin and opioids in the periaqueductal gray. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 45. issue 4. 2013-07-03. PMID:22437485. |
the first assumes that panic patients have deficient serotonergic inhibition of neurons localized in the dorsal periaqueductal gray matter of the midbrain that organize defensive reactions to cope with proximal threats and of sympathomotor control areas of the rostral ventrolateral medulla that generate most of the neurovegetative symptoms of the panic attack. |
2013-07-03 |
2023-08-12 |
human |
| Gilda Baccini, Boris Mlinar, Enrica Audero, Cornelius Thilo Gross, Renato Corradett. Impaired chemosensitivity of mouse dorsal raphe serotonergic neurons overexpressing serotonin 1A (Htr1a) receptors. PloS one. vol 7. issue 9. 2013-02-26. PMID:23028768. |
since midbrain serotonergic neurons are chemosensitive and are implicated in arousal we hypothesized that their chemosensitivity might be impaired in htr1a(ro) mice. |
2013-02-26 |
2023-08-12 |
mouse |
| Adi Neufeld-Cohen, Paul A T Kelly, Evan D Paul, Roderick N Carter, Elizabeth Skinner, Henry J Olverman, Joan M Vaughan, Orna Issler, Yael Kuperman, Christopher A Lowry, Wylie W Vale, Jonathan R Seckl, Alon Chen, Pauline M Jamieso. Chronic activation of corticotropin-releasing factor type 2 receptors reveals a key role for 5-HT1A receptor responsiveness in mediating behavioral and serotonergic responses to stressful challenge. Biological psychiatry. vol 72. issue 6. 2013-01-22. PMID:22704666. |
crfr2 in the midbrain raphé nuclei modulate serotonergic activity of this key source of serotonin (5-ht) forebrain innervation. |
2013-01-22 |
2023-08-12 |
Not clear |
| Anayansi Molina-Hernández, Néstor Fabián Díaz, José-Antonio Arias-Montañ. Histamine in brain development. Journal of neurochemistry. vol 122. issue 5. 2012-10-31. PMID:22776024. |
some relevant findings are the existence of a transient histaminergic neuronal system during brain development, which includes serotonergic neurons in the midbrain and the rhombencephalon that coexpress histamine; the high levels of histamine found in several areas of the embryo nervous system at the neurogenic stage; the presence of histaminergic fibers and the expression of histamine receptors in various areas of the developing brain; and the neurogenic and proliferative effects on neural stem cells following histamine h(1) - and h(2) -receptor activation, respectively. |
2012-10-31 |
2023-08-12 |
Not clear |
| Matthew W Hale, Anantha Shekhar, Christopher A Lowr. Stress-related serotonergic systems: implications for symptomatology of anxiety and affective disorders. Cellular and molecular neurobiology. vol 32. issue 5. 2012-10-17. PMID:22484834. |
previous studies have suggested that serotonergic neurons in the midbrain raphe complex have a functional topographic organization. |
2012-10-17 |
2023-08-12 |
Not clear |
| Hidenori Aizawa, Ryunosuke Amo, Hitoshi Okamot. Phylogeny and ontogeny of the habenular structure. Frontiers in neuroscience. vol 5. 2012-10-02. PMID:22203792. |
habenula is an epithalamic nucleus connecting the forebrain with the ventral midbrain and hindbrain that plays a pivotal role in decision making by regulating dopaminergic and serotonergic activities. |
2012-10-02 |
2023-08-12 |
human |
| Ying Huang, Lei Zhang, Ning-Ning Song, Ze-Lan Hu, Jia-Yin Chen, Yu-Qiang Din. Distribution of Satb1 in the central nervous system of adult mice. Neuroscience research. vol 71. issue 1. 2012-05-22. PMID:21658419. |
double immunostaining showed that satb1 was expressed in midbrain dopaminergic neurons, but not in cholinergic or serotonergic neurons. |
2012-05-22 |
2023-08-12 |
mouse |