| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sahel Kumar, Zsofia Gal, Xenia Gonda, Robin J Huse, Gabriella Juhasz, Gyorgy Bagdy, Peter Petschne. Transcriptomic changes following chronic administration of selective serotonin reuptake inhibitors: a review of animal studies. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. vol 21. issue 1. 2019-04-26. PMID:30962407. |
in contrast, tryptophan hydroxylase 2 appeared to be downregulated in serotonergic nuclei, and upregulated in the midbrain regions. |
2019-04-26 |
2023-08-13 |
Not clear |
| Enaam Chleilat, Lena Skatulla, Belal Rahhal, Manal T Hussein, Melanie Feuerstein, Kerstin Krieglstein, Eleni Rouss. TGF-β Signaling Regulates Development of Midbrain Dopaminergic and Hindbrain Serotonergic Neuron Subgroups. Neuroscience. vol 381. 2019-04-05. PMID:29689292. |
molecular and functional diversity within midbrain dopaminergic (mda) and hindbrain serotonergic (5-ht) neurons has emerged as a relevant feature that could underlie selective vulnerability of neurons in clinical disorders. |
2019-04-05 |
2023-08-13 |
Not clear |
| Erik Södersten, Konstantinos Toskas, Vilma Rraklli, Katarina Tiklova, Åsa K Björklund, Markus Ringnér, Thomas Perlmann, Johan Holmber. A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons. Nature communications. vol 9. issue 1. 2018-12-11. PMID:29581424. |
here, using a strategy that allows for chip-seq combined with rna-seq in small neuronal populations in vivo, we present a comparative analysis of permissive and repressive histone modifications in adult midbrain dopaminergic neurons, raphe nuclei serotonergic neurons, and embryonic neural progenitors. |
2018-12-11 |
2023-08-13 |
Not clear |
| M Allie Holschbach, Erika M Vitale, Joseph S Lonstei. Serotonin-specific lesions of the dorsal raphe disrupt maternal aggression and caregiving in postpartum rats. Behavioural brain research. vol 348. 2018-11-05. PMID:29653128. |
postpartum anxiety may rely more on other neurochemical systems or different midbrain serotonergic cell populations. |
2018-11-05 |
2023-08-13 |
rat |
| Cheng Xue Du, Jian Liu, Yuan Guo, Li Zhang, Qiao Jun Zhan. Lesions of the lateral habenula improve working memory performance in hemiparkinsonian rats. Neuroscience letters. vol 662. 2018-06-29. PMID:29054431. |
the lateral habenula (lhb) is an important structure involved in various brain functions, because it controls the activity of dopaminergic and serotonergic systems in the midbrain. |
2018-06-29 |
2023-08-13 |
rat |
| Akihiro Mouri, Yukihiro Noda, Minae Niwa, Yurie Matsumoto, Takayoshi Mamiya, Atsumi Nitta, Kiyofumi Yamada, Shoei Furukawa, Tatsunori Iwamura, Toshitaka Nabeshim. The involvement of brain-derived neurotrophic factor in 3,4-methylenedioxymethamphetamine-induced place preference and behavioral sensitization. Behavioural brain research. vol 329. 2018-03-15. PMID:28472632. |
these results suggest that bdnf is implicated in mdma-induced dependence and psychosis by activating the midbrain serotonergic and dopaminergic neurons. |
2018-03-15 |
2023-08-13 |
mouse |
| Joshua G Davimes, Abdulaziz N Alagaili, Nigel C Bennett, Osama B Mohammed, Adhil Bhagwandin, Paul R Manger, Nadine Gravet. Neurochemical organization and morphology of the sleep related nuclei in the brain of the Arabian oryx, Oryx leucoryx. Journal of chemical neuroanatomy. vol 81. 2018-02-06. PMID:28163217. |
the nuclei delineated include those revealed immunohistochemically as belonging to the cholinergic, catecholaminergic, serotonergic and orexinergic systems within the basal forebrain, hypothalamus, midbrain and pons. |
2018-02-06 |
2023-08-13 |
Not clear |
| Karl-Jürgen Bär, Feliberto de la Cruz, Andy Schumann, Stefanie Koehler, Heinrich Sauer, Hugo Critchley, Gerd Wagne. Functional connectivity and network analysis of midbrain and brainstem nuclei. NeuroImage. vol 134. 2018-01-23. PMID:27046112. |
by means of univariate functional connectivity and graph-based analysis, we show that dopaminergic midbrain centers and the serotonergic dorsal raphe nucleus (drn) are functionally integrated with the default mode network (dmn), whereas the remaining serotonergic raphe nuclei and the noradrenergic locus coeruleus are functionally integrated with the executive-control network (ecn). |
2018-01-23 |
2023-08-13 |
human |
| M Allie Holschbach, Joseph S Lonstei. Motherhood and infant contact regulate neuroplasticity in the serotonergic midbrain dorsal raphe. Psychoneuroendocrinology. vol 76. 2017-12-12. PMID:27898359. |
motherhood and infant contact regulate neuroplasticity in the serotonergic midbrain dorsal raphe. |
2017-12-12 |
2023-08-13 |
rat |
| M Allie Holschbach, Joseph S Lonstei. Motherhood and infant contact regulate neuroplasticity in the serotonergic midbrain dorsal raphe. Psychoneuroendocrinology. vol 76. 2017-12-12. PMID:27898359. |
our results demonstrate for the first time that cytogenesis occurs in the midbrain dr of any adult mammal, that dr plasticity is influenced by female reproductive state and maternal experience, and that this plasticity is accompanied by changes in dr serotonergic function. |
2017-12-12 |
2023-08-13 |
rat |
| b' J Gasull-Cam\\xc3\\xb3s, M Tarr\\xc3\\xa9s-Gatius, F Artigas, A Casta\\xc3\\xb1\\xc3\\xa. Glial GLT-1 blockade in infralimbic cortex as a new strategy to evoke rapid antidepressant-like effects in rats. Translational psychiatry. vol 7. issue 2. 2017-11-16. PMID:28221365.' |
the dhk-evoked antidepressant-like responses appear to be mediated by an ampa-r-driven enhancement of serotonergic activity, as (i) they were prevented by nbqx 2,3-dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide disodium salt) and mimicked by s-ampa; (ii) dhk and s-ampa elevated similarly extracellular glutamate in il and prl, although extracellular 5-ht and c-fos expression in the midbrain dorsal raphe increased only when these agents were applied in il; and (iii) dhk antidepressant-like responses were prevented by 5-ht synthesis inhibition and mimicked by citalopram microinfusion in il. |
2017-11-16 |
2023-08-13 |
rat |
| Frederico G Graef. Translational approach to the pathophysiology of panic disorder: Focus on serotonin and endogenous opioids. Neuroscience and biobehavioral reviews. vol 76. issue Pt A. 2017-10-30. PMID:28073587. |
the first suggests that panic patients have deficient serotonergic inhibition of neurons localized in the dorsal periaqueductal gray matter of the midbrain that organizes defensive reactions to cope with proximal threats as well as of sympathomotor control areas of the rostral ventrolateral medulla that generate neurovegetative symptoms of the panic attack. |
2017-10-30 |
2023-08-13 |
human |
| Vincent van de Ven, Marleen Wingen, Kim P C Kuypers, Johannes G Ramaekers, Elia Formisan. Escitalopram Decreases Cross-Regional Functional Connectivity within the Default-Mode Network. PloS one. vol 8. issue 6. 2017-10-11. PMID:23826388. |
the serotonergic (5-ht) neurotransmitter system projects to dmn regions from midbrain efferents, and manipulation of this system could thus reveal insights into the neurobiological mechanisms of dmn functioning. |
2017-10-11 |
2023-08-12 |
human |
| Sebastian Pablo Fernandez, Bruno Cauli, Carolina Cabezas, Aude Muzerelle, Jean-Christophe Poncer, Patricia Gaspa. Multiscale single-cell analysis reveals unique phenotypes of raphe 5-HT neurons projecting to the forebrain. Brain structure & function. vol 221. issue 8. 2017-10-10. PMID:26608830. |
overall, these findings allow to define correlated anatomical and physiological identities of serotonin raphe neurons that help understanding how discrete raphe cells subpopulations account for the heterogeneous activities of the midbrain serotonergic system. |
2017-10-10 |
2023-08-13 |
mouse |
| Susan E Maloney, Eakta Khangura, Joseph D Doughert. The RNA-binding protein Celf6 is highly expressed in diencephalic nuclei and neuromodulatory cell populations of the mouse brain. Brain structure & function. vol 221. issue 4. 2017-10-03. PMID:25682262. |
the greatest protein expression was observed in distinct nuclei of the diencephalon and neuromodulatory cell populations of the midbrain and hindbrain, with clear expression in dopaminergic, noradrenergic, histaminergic, serotonergic and cholinergic populations, and a variety of presumptive peptidergic cells of the hypothalamus. |
2017-10-03 |
2023-08-13 |
mouse |
| N N Kudryavtseva, D A Smagin, I L Kovalenko, A G Galyamina, G B Vishnivetskaya, V N Babenko, Yu L Orlo. [Serotonergic genes in the development of anxiety/depression-like state and pathology of aggressive behavior in male mice: RNA-seq data]. Molekuliarnaia biologiia. vol 51. issue 2. 2017-08-14. PMID:28537235. |
using the data of whole transcriptome analysis (rna-seq), the changes in the expression of serotonergic genes involved in the synthesis, inactivation, and reception of serotonin, as well as of the creb1 (transcription factor) gene and the bdnf (brain-derived neurotrophic factor) gene were detected in the striatum (str), ventral tegmental area (vta), midbrain raphe nuclei (mrn), hypothalamus (hyp), and hippocampus (hip) of defeated and aggressive male mice. |
2017-08-14 |
2023-08-13 |
mouse |
| Nozomi Asaoka, Hiroyuki Kawai, Naoya Nishitani, Haruko Kinoshita, Norihiro Shibui, Kazuki Nagayasu, Hisashi Shirakawa, Shuji Kanek. A new designer drug 5F-ADB activates midbrain dopaminergic neurons but not serotonergic neurons. The Journal of toxicological sciences. vol 41. issue 6. 2017-04-11. PMID:27853110. |
a new designer drug 5f-adb activates midbrain dopaminergic neurons but not serotonergic neurons. |
2017-04-11 |
2023-08-13 |
Not clear |
| Nozomi Asaoka, Hiroyuki Kawai, Naoya Nishitani, Haruko Kinoshita, Norihiro Shibui, Kazuki Nagayasu, Hisashi Shirakawa, Shuji Kanek. A new designer drug 5F-ADB activates midbrain dopaminergic neurons but not serotonergic neurons. The Journal of toxicological sciences. vol 41. issue 6. 2017-04-11. PMID:27853110. |
to investigate the neuronal mechanisms underlying its toxicity, we examined the effects of 5f-adb on midbrain dopaminergic and serotonergic systems, which modulate various basic brain functions such as those in reward-related behavior. |
2017-04-11 |
2023-08-13 |
Not clear |
| Ilya Ayzenberg, Ilias Nastos, Katrin Strassburger-Krogias, Mark Obermann, Ralf Gold, Christos Krogia. Hypoechogenicity of brainstem raphe nuclei is associated with increased attack frequency in episodic migraine. Cephalalgia : an international journal of headache. vol 36. issue 8. 2017-03-02. PMID:26566936. |
postulating that migraine may constitute a "chronic low serotonin syndrome," we aimed to evaluate the echogenicity of midbrain structures, including serotonergic brn in episodic migraine. |
2017-03-02 |
2023-08-13 |
Not clear |
| Tsukasa Ishiguro, Hiromi Sakata-Haga, Yoshihiro Fuku. A 5-HT2A/2C receptor agonist, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane, mitigates developmental neurotoxicity of ethanol to serotonergic neurons. Congenital anomalies. vol 56. issue 4. 2017-02-06. PMID:26714672. |
prenatal ethanol exposure causes the reduction of serotonergic (5-htergic) neurons in the midbrain raphe nuclei. |
2017-02-06 |
2023-08-13 |
rat |