| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chang-Hong Wang, Cong Liu, En-Zhao Cong, Gai-Ling Xu, Ting-Ting Lv, Ying-Li Zhang, Qiu-Fen Ning, Ji-Kang Wang, Hui-Yao Nie, Yan L. Association of tryptophan hydroxylase-2 polymorphisms with oppositional defiant disorder in a Chinese Han population. Behavioral and brain functions : BBF. vol 12. issue 1. 2017-01-23. PMID:27871272. |
the enzyme tryptophan hydroxylase-2 (tph-2) synthesizes 5-ht in serotonergic neurons of the midbrain raphe. |
2017-01-23 |
2023-08-13 |
Not clear |
| Sarah M Keesom, Laura M Hurle. Socially induced serotonergic fluctuations in the male auditory midbrain correlate with female behavior during courtship. Journal of neurophysiology. vol 115. issue 4. 2016-12-19. PMID:26792882. |
socially induced serotonergic fluctuations in the male auditory midbrain correlate with female behavior during courtship. |
2016-12-19 |
2023-08-13 |
mouse |
| Sarah M Keesom, Laura M Hurle. Socially induced serotonergic fluctuations in the male auditory midbrain correlate with female behavior during courtship. Journal of neurophysiology. vol 115. issue 4. 2016-12-19. PMID:26792882. |
we addressed this issue by using voltammetry to monitor serotonergic fluctuations in an auditory midbrain nucleus, the inferior colliculus (ic), of male mice (mus musculus) paired with females, and by concurrently measuring behaviors of both social partners. |
2016-12-19 |
2023-08-13 |
mouse |
| Brice Le François, Jeremy Soo, Anne M Millar, Mireille Daigle, Anne-Marie Le Guisquet, Samuel Leman, Frédéric Minier, Catherine Belzung, Paul R Alber. Chronic mild stress and antidepressant treatment alter 5-HT1A receptor expression by modifying DNA methylation of a conserved Sp4 site. Neurobiology of disease. vol 82. 2016-08-24. PMID:26188176. |
in prefrontal cortex (pfc) and midbrain tissue, ucms increased 5-ht1a rna and protein levels, changes that are expected to decrease the brain serotonergic activity. |
2016-08-24 |
2023-08-13 |
mouse |
| Qiong Zhan, Gordon F Buchanan, Joshua E Motelow, John Andrews, Petr Vitkovskiy, William C Chen, Florian Serout, Abhijeet Gummadavelli, Adam Kundishora, Moran Furman, Wei Li, Xiao Bo, George B Richerson, Hal Blumenfel. Impaired Serotonergic Brainstem Function during and after Seizures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 9. 2016-08-16. PMID:26937010. |
in contrast, firing of midbrain raphe serotonergic neurons was more variable, with a mixture of increases and decreases. |
2016-08-16 |
2023-08-13 |
rat |
| Claudia Böhm, Maria Pangalos, Dietmar Schmitz, Jochen Wintere. Serotonin Attenuates Feedback Excitation onto O-LM Interneurons. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 11. 2016-07-18. PMID:26021702. |
in the hippocampus, serotonin (5-ht) is released by ascending serotonergic fibers from the midbrain raphe nuclei, thereby mediating numerous modulatory functions on various neuronal subtypes. |
2016-07-18 |
2023-08-13 |
rat |
| Laura Lahti, Maarja Haugas, Laura Tikker, Mikko Airavaara, Merja H Voutilainen, Jenni Anttila, Suman Kumar, Caisa Inkinen, Marjo Salminen, Juha Partane. Differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei. Development (Cambridge, England). vol 143. issue 3. 2016-07-11. PMID:26718003. |
local inhibitory gabaergic and excitatory glutamatergic neurons are important for midbrain dopaminergic and hindbrain serotonergic pathways controlling motivation, mood, and voluntary movements. |
2016-07-11 |
2023-08-13 |
Not clear |
| Galina T Shishkina, Tatyana S Kalinina, Veta V Bulygina, Dmitry A Lanshakov, Ekaterina V Babluk, Nikolay N Dygal. Anti-Apoptotic Protein Bcl-xL Expression in the Midbrain Raphe Region Is Sensitive to Stress and Glucocorticoids. PloS one. vol 10. issue 12. 2016-06-20. PMID:26624017. |
in order to determine whether stressful events may influence the expression of anti-apoptotic protein bcl-xl in the midbrain and specifically in the midbrain serotonergic (5-ht) neurons involved in neurobehavioral responses to adverse stimuli, adult male rats were subjected to short-term or chronic forced swim stress. |
2016-06-20 |
2023-08-13 |
rat |
| Noah H Green, Chad R Jackson, Hideki Iwamoto, Michael C Tackenberg, Douglas G McMaho. Photoperiod programs dorsal raphe serotonergic neurons and affective behaviors. Current biology : CB. vol 25. issue 10. 2016-04-21. PMID:25959961. |
the serotonergic raphe nuclei of the midbrain are principal centers from which serotonin neurons project to innervate cortical and sub-cortical structures. |
2016-04-21 |
2023-08-13 |
mouse |
| N N Kudryavtsev. [Serotonergic Control of Aggressive Behavior: Novel Approaches--New Interpretations (Review)]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 65. issue 5. 2016-03-24. PMID:26859999. |
it has been shown that mrna levels of the serotonergic genes in the midbrain raphe nuclei are reduced in aggressive males. |
2016-03-24 |
2023-08-13 |
mouse |
| Willemieke M Kouwenhoven, Jesse V Veenvliet, Johannes A van Hooft, L P van der Heide, Marten P Smid. Engrailed 1 shapes the dopaminergic and serotonergic landscape through proper isthmic organizer maintenance and function. Biology open. vol 5. issue 3. 2016-03-16. PMID:26879466. |
the isthmic organizer (iso) is a signaling center that specifies the correct and distinct embryonic development of the dopaminergic midbrain and serotonergic hindbrain. |
2016-03-16 |
2023-08-13 |
mouse |
| Willemieke M Kouwenhoven, Jesse V Veenvliet, Johannes A van Hooft, L P van der Heide, Marten P Smid. Engrailed 1 shapes the dopaminergic and serotonergic landscape through proper isthmic organizer maintenance and function. Biology open. vol 5. issue 3. 2016-03-16. PMID:26879466. |
erroneous composition of dopaminergic neurons in the midbrain or serotonergic neurons in the hindbrain is associated with severe pathologies such as parkinson's disease, depression or autism. |
2016-03-16 |
2023-08-13 |
mouse |
| Shelby E R Wauson, Kwaku Sarkodie, Lindsey M Schuette, Paul J Curri. Midbrain raphe 5-HT1A receptor activation alters the effects of ghrelin on appetite and performance in the elevated plus maze. Journal of psychopharmacology (Oxford, England). vol 29. issue 7. 2016-03-11. PMID:25922422. |
prior research suggests that midbrain serotonergic signaling and hypothalamic ghrelinergic signaling both play critical roles in appetitive and emotional behaviors. |
2016-03-11 |
2023-08-13 |
rat |
| S Ma, A L Gundlac. Ascending control of arousal and motivation: role of nucleus incertus and its peptide neuromodulators in behavioural responses to stress. Journal of neuroendocrinology. vol 27. issue 6. 2016-03-01. PMID:25612218. |
established modulators of arousal include the cholinergic, serotonergic, noradrenergic and dopaminergic networks originating in the pons and midbrain. |
2016-03-01 |
2023-08-13 |
Not clear |
| Juho Joutsa, Jarkko Johansson, Marko Seppänen, Tommi Noponen, Valtteri Kaasine. Dorsal-to-Ventral Shift in Midbrain Dopaminergic Projections and Increased Thalamic/Raphe Serotonergic Function in Early Parkinson Disease. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 56. issue 7. 2015-09-22. PMID:25952735. |
dorsal-to-ventral shift in midbrain dopaminergic projections and increased thalamic/raphe serotonergic function in early parkinson disease. |
2015-09-22 |
2023-08-13 |
Not clear |
| Prem Prakash Tripathi, Yuri Bozz. The role of dopaminergic and serotonergic systems in neurodevelopmental disorders: a focus on epilepsy and seizure susceptibility. BioImpacts : BI. vol 5. issue 2. 2015-07-20. PMID:26191504. |
dopaminergic and serotonergic neurons, located in midbrain and hindbrain regions respectively, diffusely innervate several forebrain areas including limbic system, contributing in regulating several physiological functions. |
2015-07-20 |
2023-08-13 |
Not clear |
| Newton S Canteras, Frederico G Graef. Executive and modulatory neural circuits of defensive reactions: implications for panic disorder. Neuroscience and biobehavioral reviews. vol 46 Pt 3. 2015-07-17. PMID:24709069. |
the present review covers two independent approaches, a neuroanatomical and a pharmacological (focused on serotonergic transmission), which converge in highlighting the critical role of the hypothalamus and midbrain periaqueductal gray matter in the generation of panic attacks and in the mechanism of action of current antipanic medication. |
2015-07-17 |
2023-08-13 |
Not clear |
| Julian Macoveanu, Patrick M Fisher, Mette E Haahr, Vibe G Frokjaer, Gitte M Knudsen, Hartwig R Siebne. Effects of selective serotonin reuptake inhibition on neural activity related to risky decisions and monetary rewards in healthy males. NeuroImage. vol 99. 2015-04-13. PMID:24857827. |
this midbrain cluster included the raphe nuclei from which serotonergic modulatory projections originate to both cortical and subcortical regions. |
2015-04-13 |
2023-08-13 |
human |
| Andreas Hahn, Daniela Haeusler, Christoph Kraus, Anna S Höflich, Georg S Kranz, Pia Baldinger, Markus Savli, Markus Mitterhauser, Wolfgang Wadsak, Georgios Karanikas, Siegfried Kasper, Rupert Lanzenberge. Attenuated serotonin transporter association between dorsal raphe and ventral striatum in major depression. Human brain mapping. vol 35. issue 8. 2015-02-27. PMID:24443158. |
in addition, sert bpnd was extracted from the dorsal raphe nucleus (drn) as an indicator of midbrain serotonergic neurotransmission. |
2015-02-27 |
2023-08-12 |
human |
| Iskra Pollak Dorocic, Daniel Fürth, Yang Xuan, Yvonne Johansson, Laura Pozzi, Gilad Silberberg, Marie Carlén, Konstantinos Meleti. A whole-brain atlas of inputs to serotonergic neurons of the dorsal and median raphe nuclei. Neuron. vol 83. issue 3. 2014-12-29. PMID:25102561. |
we identified discrete inputs onto serotonergic neurons from forebrain and brainstem neurons, with specific inputs from hypothalamus, cortex, basal ganglia, and midbrain, displaying a greater than anticipated complexity and diversity in cell-type-specific connectivity. |
2014-12-29 |
2023-08-13 |
Not clear |