| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R A Armstrong, P L Lantos, N J Cairn. Progressive supranuclear palsy (PSP): a quantitative study of the pathological changes in cortical and subcortical regions of eight cases. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 12. 2008-05-28. PMID:17680229. |
loss of purkinje cells was evident in the cerebellum. |
2008-05-28 |
2023-08-12 |
Not clear |
| Kunihiko Obata, Moritoshi Hirono, Nobuko Kume, Yoshiya Kawaguchi, Shigeyoshi Itohara, Yuchio Yanagaw. GABA and synaptic inhibition of mouse cerebellum lacking glutamate decarboxylase 67. Biochemical and biophysical research communications. vol 370. issue 3. 2008-05-22. PMID:18384748. |
however, the morphology of purkinje cells and the density of synaptic terminals in the cerebellar cortex appeared unaffected, suggesting that gaba does not participate in cerebellar development substantially. |
2008-05-22 |
2023-08-12 |
mouse |
| Satoru Ota, Kuniaki Tsuchiya, Midori Anno, Kazuhiro Niizato, Haruhiko Akiyam. Distribution of cerebello-olivary degeneration in idiopathic late cortical cerebellar atrophy: clinicopathological study of four autopsy cases. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 28. issue 1. 2008-05-21. PMID:18181834. |
in all four cases, the most obvious pathological finding throughout the cerebellum was loss of purkinje cells, but the rarefaction of granular cell layers was observed only where loss of purkinje cells was very severe, and thinning of the molecular layer was seen only where the rarefaction of granular cell layers was moderate to severe. |
2008-05-21 |
2023-08-12 |
Not clear |
| Robert Stallmach, Sergio M Gloo. Neurobin/TMPRSS11c, a novel type II transmembrane serine protease that cleaves fibroblast growth factor-2 in vitro. The Biochemical journal. vol 412. issue 1. 2008-05-21. PMID:18215125. |
histochemical analysis of brain sections revealed distinct staining of purkinje neurons of the cerebellum. |
2008-05-21 |
2023-08-12 |
mouse |
| Milena Laure-Kamionowska, Danuta Maślińsk. Astroglia and microglia in cerebellar neuronal migration disturbances. Folia neuropathologica. vol 45. issue 4. 2008-05-20. PMID:18176894. |
in the cerebellar cortical malformations astrocytes were grouped near the purkinje cells. |
2008-05-20 |
2023-08-12 |
Not clear |
| N Spassky, Y-G Han, A Aguilar, L Strehl, L Besse, C Laclef, M Romaguera Ros, J M Garcia-Verdugo, A Alvarez-Buyll. Primary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool. Developmental biology. vol 317. issue 1. 2008-05-19. PMID:18353302. |
sonic hedgehog (shh) secreted by developing purkinje cells is essential for the expansion of gcps and for cerebellar morphogenesis. |
2008-05-19 |
2023-08-12 |
mouse |
| Barbara Carletti, Ian Martin Williams, Ketty Leto, Kazunori Nakajima, Lorenzo Magrassi, Ferdinando Ross. Time constraints and positional cues in the developing cerebellum regulate Purkinje cell placement in the cortical architecture. Developmental biology. vol 317. issue 1. 2008-05-19. PMID:18384765. |
to elucidate the mechanisms that regulate neuronal placement and integration in the cerebellar circuitry, we assessed the fate of purkinje cells transplanted to embryonic, juvenile and adult hosts, asking how architectural changes of the developing cortex influence their anatomical incorporation. |
2008-05-19 |
2023-08-12 |
Not clear |
| Barbara Carletti, Ian Martin Williams, Ketty Leto, Kazunori Nakajima, Lorenzo Magrassi, Ferdinando Ross. Time constraints and positional cues in the developing cerebellum regulate Purkinje cell placement in the cortical architecture. Developmental biology. vol 317. issue 1. 2008-05-19. PMID:18384765. |
therefore, although the cerebellar milieu remains receptive for purkinje cells even after the end of development, correct placement of donor neurons depends on the timing of their migration, related to cerebellar developmental dynamics and granule cell layering. |
2008-05-19 |
2023-08-12 |
Not clear |
| Tomoya Nakamachi, Hirokazu Ohtaki, Sachiko Yofu, Kenji Dohi, Jun Watanabe, Daisuke Hayashi, Ryosuke Matsuno, Naoko Nonaka, Kazuo Itabashi, Seiji Shiod. Pituitary adenylate cyclase-activating polypeptide (PACAP) type 1 receptor (PAC1R) co-localizes with activity-dependent neuroprotective protein (ADNP) in the mouse brains. Regulatory peptides. vol 145. issue 1-3. 2008-05-06. PMID:17942168. |
adnp-immunoreactive cells in the cerebellum were found to surround purkinje cells and showed gfap immunoreactivity. |
2008-05-06 |
2023-08-12 |
mouse |
| Carolina Aguado, José Colón, Francisco Ciruela, Falk Schlaudraff, Maria José Cabañero, Cydne Perry, Masahiko Watanabe, Birgit Liss, Kevin Wickman, Rafael Lujá. Cell type-specific subunit composition of G protein-gated potassium channels in the cerebellum. Journal of neurochemistry. vol 105. issue 2. 2008-05-06. PMID:18088366. |
a high degree of molecular diversity in the cerebellar girk channel repertoire is suggested by labeling seen in less abundant neuron populations, including purkinje neurons (girk1/girk2/girk3), basket cells (girk1/girk3), golgi cells (girk2/girk4), stellate cells (girk3), and unipolar brush cells (girk2/girk3). |
2008-05-06 |
2023-08-12 |
mouse |
| Eriko Fujita, Yuko Tanabe, Akira Shiota, Masatsugu Ueda, Kiyotaka Suwa, Mariko Y Momoi, Takashi Momo. Ultrasonic vocalization impairment of Foxp2 (R552H) knockin mice related to speech-language disorder and abnormality of Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 8. 2008-04-29. PMID:18287060. |
homozygous foxp2 (r552h)-ki mice showed reduced weight, immature development of the cerebellum with incompletely folded folia, purkinje cells with poor dendritic arbors and less synaptophysin immunoreactivity, and achieved crisis stage for survival 3 weeks after birth. |
2008-04-29 |
2023-08-12 |
mouse |
| Eriko Fujita, Yuko Tanabe, Akira Shiota, Masatsugu Ueda, Kiyotaka Suwa, Mariko Y Momoi, Takashi Momo. Ultrasonic vocalization impairment of Foxp2 (R552H) knockin mice related to speech-language disorder and abnormality of Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 8. 2008-04-29. PMID:18287060. |
in addition to the immature development of the cerebellum, foxp2 (r552h) nuclear aggregates may further compromise the function of the purkinje cells and cerebral neurons of the homozygous mice, resulting in their death. |
2008-04-29 |
2023-08-12 |
mouse |
| Karel Zitterbart, Iva Zavrelova, Jitka Kadlecova, Renata Spesna, Adela Kratochvilova, Zdenek Pavelka, Jaroslav Sterb. p73 expression in medulloblastoma: TAp73/DeltaNp73 transcript detection and possible association of p73alpha/DeltaNp73 immunoreactivity with survival. Acta neuropathologica. vol 114. issue 6. 2008-04-25. PMID:17912537. |
in normal cerebellum, positive staining for p73alpha and deltanp73 was observed in the purkinje cells of newborns, not adult samples, which supports the developmental role of tp73 during organogenesis of the human cerebellum. |
2008-04-25 |
2023-08-12 |
human |
| Kye-Young Kim, Sachiyo Kawamoto, Jianjun Bao, James R Sellers, Robert S Adelstei. The B2 alternatively spliced isoform of nonmuscle myosin II-B lacks actin-activated MgATPase activity and in vitro motility. Biochemical and biophysical research communications. vol 369. issue 1. 2008-04-17. PMID:18060863. |
nm ii-b2 is expressed in the purkinje cells of the cerebellum as well as in other neuronal cells [x. ma, s. kawamoto, j. uribe, r.s. |
2008-04-17 |
2023-08-12 |
mouse |
| Shinji Ohara, Naoko Iijima, Kensuke Hayashida, Takashi Oide, Satoshi Kata. Autopsy case of opsoclonus-myoclonus-ataxia and cerebellar cognitive affective syndrome associated with small cell carcinoma of the lung. Movement disorders : official journal of the Movement Disorder Society. vol 22. issue 9. 2008-04-16. PMID:17534981. |
neuropathologically, only the cerebellum was affected, with diffuse loss of purkinje cells and dentate neurons, suggesting that the paraneoplastic cerebellar involvement may be responsible for the cognitive affective symptoms in our patient. |
2008-04-16 |
2023-08-12 |
Not clear |
| M D Glitsc. Calcium influx through N-methyl-D-aspartate receptors triggers GABA release at interneuron-Purkinje cell synapse in rat cerebellum. Neuroscience. vol 151. issue 2. 2008-04-15. PMID:18055124. |
it was shown that activation of n-methyl-d-aspartate (nmda) receptors on presynaptic interneurons led to increases in gaba release from these neurons onto postsynaptic purkinje cells in rat cerebellum in the presence of tetrodotoxin (ttx), suggesting a presynaptic location for the underlying nmda receptors. |
2008-04-15 |
2023-08-12 |
rat |
| Sarah Donald, Trevor Humby, Ian Fyfe, Anne Segonds-Pichon, Simon A Walker, Simon R Andrews, W John Coadwell, Piers Emson, Lawrence S Wilkinson, Heidi C E Welc. P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 11. 2008-04-15. PMID:18334636. |
we show here that, whereas p-rex1 expression within the brain is widespread, p-rex2 is specifically expressed in the purkinje neurons of the cerebellum. |
2008-04-15 |
2023-08-12 |
mouse |
| Pauline Cavelier, Ann M Lohof, Etienne Lonchamp, Huguette Beekenkamp, Jean Mariani, Jean-Louis Boss. Participation of low-threshold Ca2+ spike in the Purkinje cells complex spike. Neuroreport. vol 19. issue 3. 2008-04-09. PMID:18303570. |
in purkinje cells from cerebellar slice cultures, low-threshold ca spike (lts) gives rise to complex bursts in the soma that resemble the complex spike induced by climbing fibers stimulation. |
2008-04-09 |
2023-08-12 |
Not clear |
| Fa-Ren Zhang, Li-Hua Tao, Zhong-Ying Shen, Zhuo Lv, Li-Yan Xu, En-Min L. Fascin expression in human embryonic, fetal, and normal adult tissue. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 56. issue 2. 2008-04-03. PMID:17998567. |
in later developmental stages and in adults, purkinje cells of the cerebellum and glandular epithelium of the gastrointestinal tract showed no expression. |
2008-04-03 |
2023-08-12 |
human |
| Tomohiko Okuda, Koichi Kokame, Toshiyuki Miyat. Differential expression patterns of NDRG family proteins in the central nervous system. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 56. issue 2. 2008-04-03. PMID:17998568. |
in the cerebellum, ndrg1 and ndrg4 were localized in purkinje cells and ndrg2 in bergmann glial cells. |
2008-04-03 |
2023-08-12 |
mouse |