| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Janet C Rucker, R John Leigh, Lance M Optican, Edward L Keller, Jean A Bu Ttner-Enneve. Ocular motor anatomy in a case of interrupted saccades. Progress in brain research. vol 171. 2009-01-15. PMID:18718354. |
purkinje cells were absent and gliosis of the granular cell layer was present in the dorsal cerebellar vermis. |
2009-01-15 |
2023-08-12 |
Not clear |
| Shannon L Macauley, Richard L Sidman, Edward H Schuchman, Tatyana Taksir, Gregory R Stewar. Neuropathology of the acid sphingomyelinase knockout mouse model of Niemann-Pick A disease including structure-function studies associated with cerebellar Purkinje cell degeneration. Experimental neurology. vol 214. issue 2. 2009-01-07. PMID:18778708. |
of particular interest was the degeneration of purkinje cells (pc) within the cerebellum, beginning by 7 weeks of age in parasagittal bands and culminating with near complete degeneration of this cell type by 20 weeks. |
2009-01-07 |
2023-08-12 |
mouse |
| Kiyohiko Takayama, Takashi Torashima, Hajime Horiuchi, Hirokazu Hira. Purkinje-cell-preferential transduction by lentiviral vectors with the murine stem cell virus promoter. Neuroscience letters. vol 443. issue 1. 2009-01-05. PMID:18675313. |
viral-vector-mediated gene delivery into purkinje cells is a promising method for exploring the pathophysiology of the cerebellum; however, it is generally difficult to achieve sufficiently high levels of gene expression in purkinje cells using viral vectors with a cell-type-specific promoter because of the weakness of transcriptional activity. |
2009-01-05 |
2023-08-12 |
mouse |
| Ann Massie, Lieselotte Cnops, Ilse Smolders, Robert McCullumsmith, Ron Kooijman, Shin Kwak, Lutgarde Arckens, Yvette Michott. High-affinity Na+/K+-dependent glutamate transporter EAAT4 is expressed throughout the rat fore- and midbrain. The Journal of comparative neurology. vol 511. issue 2. 2008-12-22. PMID:18770868. |
excitatory amino acid transporter 4 (eaat4), a member of the high-affinity na+/k+-dependent glutamate transporter family, is highly enriched in purkinje cells of the cerebellum, although it is not restricted to these cells. |
2008-12-22 |
2023-08-12 |
mouse |
| Sacha Ferdinandusse, Anna W M Zomer, Jasper C Komen, Christina E van den Brink, Melissa Thanos, Frank P T Hamers, Ronald J A Wanders, Paul T van der Saag, Bwee Tien Poll-The, Pedro Brite. Ataxia with loss of Purkinje cells in a mouse model for Refsum disease. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 46. 2008-12-17. PMID:19004801. |
in addition, a loss of purkinje cells in the cerebellum was observed. |
2008-12-17 |
2023-08-12 |
mouse |
| Daniel Z Wetmore, Eran A Mukamel, Mark J Schnitze. Lock-and-key mechanisms of cerebellar memory recall based on rebound currents. Journal of neurophysiology. vol 100. issue 4. 2008-12-05. PMID:17671105. |
we explored this idea through computational studies of two cerebellar behaviors and examined whether deep cerebellar and vestibular nuclei neurons can filter signals from purkinje cells that would otherwise drive inappropriate motor responses. |
2008-12-05 |
2023-08-12 |
Not clear |
| Gregory D Ford, Byron D Ford, Ernest C Steele, Alicia Gates, Darryl Hood, Mika A B Matthews, Sophia Mirza, Peter R MacLeis. Analysis of transcriptional profiles and functional clustering of global cerebellar gene expression in PCD3J mice. Biochemical and biophysical research communications. vol 377. issue 2. 2008-12-05. PMID:18930027. |
to identify the molecular mechanisms that lead to the death of purkinje neurons in pcd mice, we used affymetrix microarray technology to compare cerebellar gene expression profiles in pcd3j mutant mice 14 days of age (prior to purkinje cell loss) to unaffected littermates. |
2008-12-05 |
2023-08-12 |
mouse |
| Lalitha R Belur, William F Kaemmerer, R Scott McIvor, Walter C Lo. Adeno-associated virus type 2 vectors: transduction and long-term expression in cerebellar Purkinje cells in vivo is mediated by the fibroblast growth factor receptor 1 : bFGFR-1 mediates AAV2 transduction of Purkinje cells. Archives of virology. vol 153. issue 11. 2008-12-02. PMID:18937030. |
these results provide new information on fibroblast growth factor receptor-1 involvement in aav2-mediated transduction of purkinje cells and have important implications for aav-mediated treatment of various cerebellar disorders. |
2008-12-02 |
2023-08-12 |
Not clear |
| Masato Mashimo, Tetsuya Hirabayashi, Toshihiko Murayama, Takao Shimiz. Cytosolic PLA2(alpha) activation in Purkinje neurons and its role in AMPA-receptor trafficking. Journal of cell science. vol 121. issue Pt 18. 2008-12-01. PMID:18713832. |
however, the subcellular distribution and activation of cpla(2)alpha in purkinje cells and the role of arachidonic acid in cerebellar ltd have not been fully elucidated. |
2008-12-01 |
2023-08-12 |
Not clear |
| C A Bourke, E C Bunker, R I Reece, S J Whittake. Cerebellar ataxia in sheep grazing pastures infested with Romulea rosea (onion grass or Guildford grass). Australian veterinary journal. vol 86. issue 9. 2008-11-17. PMID:18782418. |
the most significant changes were found in the cerebellum, where there were decreased numbers of purkinje cells, increased numbers of glial cells, scattered vacuoles and occasional swollen axons. |
2008-11-17 |
2023-08-12 |
cattle |
| Mustapha Bennay, Julia Langer, Silke D Meier, Karl W Kafitz, Christine R Ros. Sodium signals in cerebellar Purkinje neurons and Bergmann glial cells evoked by glutamatergic synaptic transmission. Glia. vol 56. issue 10. 2008-11-10. PMID:18442095. |
in the present study, we combined somatic whole-cell patch-clamp recordings with quantitative na+ imaging in fine cellular branches of cerebellar bergmann glial cells and in dendrites of purkinje neurons to analyze intracellular na+ signals close to activated synapses. |
2008-11-10 |
2023-08-12 |
Not clear |
| Javier F Medina, Stephen G Lisberge. Links from complex spikes to local plasticity and motor learning in the cerebellum of awake-behaving monkeys. Nature neuroscience. vol 11. issue 10. 2008-11-06. PMID:18806784. |
the hypothesis of cerebellar learning proposes that complex spikes in purkinje cells engage mechanisms of plasticity in the cerebellar cortex; in turn, changes in the cerebellum depress the simple-spike response of purkinje cells to a given stimulus and cause the adaptive modification of a motor behavior. |
2008-11-06 |
2023-08-12 |
monkey |
| Mitsuko Hamamura, Naotsugu Hirata, Kazuhiko Sawada, Takahide Shuto, Takao Shimazoe, Yoshihiro Terada, Yasuyuki Fukumak. Reversal of the expression pattern of Aldolase C mRNA in Purkinje cells and Ube 1x mRNA in Golgi cells by a dopamine D1 receptor agonist injections in the methamphetamine sensitized-rat cerebellum. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 7. 2008-11-05. PMID:18299792. |
reversal of the expression pattern of aldolase c mrna in purkinje cells and ube 1x mrna in golgi cells by a dopamine d1 receptor agonist injections in the methamphetamine sensitized-rat cerebellum. |
2008-11-05 |
2023-08-12 |
rat |
| K-K Tai, N Nguyen, L Pham, D D Truon. Ketogenic diet prevents cardiac arrest-induced cerebral ischemic neurodegeneration. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 7. 2008-11-05. PMID:18478178. |
they also showed signs of neurodegeneration in the purkinje cells of the cerebellum and in the thalamic reticular nucleus, the number of fj positive neurons in the cerebellum was 55+/-27 (n=4), the number of fj positive neurons in the thalamic reticular nucleus was 22+/-5 (n=4). |
2008-11-05 |
2023-08-12 |
rat |
| Yueping Zhang, Phil F Han, Victor Z Ha. Local circuitry in the anterior caudal lobe of the mormyrid cerebellum: a study of intracellular recording and labeling. The Journal of comparative neurology. vol 509. issue 1. 2008-11-04. PMID:18418897. |
thus, the anterior caudal lobe of the mormyrid cerebellum is different from the mammalian cerebellum in having different subtypes of purkinje cells and local termination of many purkinje cell axons. |
2008-11-04 |
2023-08-12 |
Not clear |
| Augusto D Luchessi, Tavane D Cambiaghi, Adilson S Alves, Lucas T Parreiras-E-Silva, Luiz R G Britto, Claudio M Costa-Neto, Rui Cur. Insights on eukaryotic translation initiation factor 5A (eIF5A) in the brain and aging. Brain research. vol 1228. 2008-11-03. PMID:18606156. |
a high content of eif5a in the soma and dendrites of purkinje cells, key neurons in the control of motor long-term memory in the cerebellum, was observed. |
2008-11-03 |
2023-08-12 |
rat |
| Ursula Höfle, Juan M Blanco, Elena Crespo, Victoria Naranjo, Miguel Angel Jiménez-Clavero, Azucena Sanchez, José de la Fuente, Christian Gortaza. West Nile virus in the endangered Spanish imperial eagle. Veterinary microbiology. vol 129. issue 1-2. 2008-10-30. PMID:18155367. |
immunohistochemistry detected wnv antigen in purkinje cells in the cerebellum, epithelial cells of the gizzard and duodenum, perivascular inflammatory cells, and in kupffer-cells and hepatocytes. |
2008-10-30 |
2023-08-12 |
Not clear |
| Leonardo Sacconi, Jonathan Mapelli, Daniela Gandolfi, Jacopo Lotti, Rodney P O'Connor, Egidio D'Angelo, Francesco S Pavon. Optical recording of electrical activity in intact neuronal networks with random access second-harmonic generation microscopy. Optics express. vol 16. issue 19. 2008-10-30. PMID:18795028. |
the rash microscope, in combination with bulk loading of tissue with fm4-64 dye, was used to simultaneously record electrical activity from clusters of purkinje cells in acute cerebellar slices. |
2008-10-30 |
2023-08-12 |
Not clear |
| J Larsson, M Forsberg, K Brännvall, X-Q Zhang, M Enarsson, F Hedborg, K Forsberg-Nilsso. Nuclear receptor binding protein 2 is induced during neural progenitor differentiation and affects cell survival. Molecular and cellular neurosciences. vol 39. issue 1. 2008-10-29. PMID:18619852. |
in the adult brain, purkinje cells of the cerebellum and neurons in the ca3 region of the hippocampus were main sites of nrbp2 expression. |
2008-10-29 |
2023-08-12 |
mouse |
| Kazushi Miya, Ran Inoue, Yoshimi Takata, Manabu Abe, Rie Natsume, Kenji Sakimura, Kazuhisa Hongou, Toshio Miyawaki, Hisashi Mor. Serine racemase is predominantly localized in neurons in mouse brain. The Journal of comparative neurology. vol 510. issue 6. 2008-10-27. PMID:18698599. |
furthermore, in the adult cerebellum, we detected weak but significant sr signals in gabaergic purkinje cells. |
2008-10-27 |
2023-08-12 |
mouse |